3.4.21.47 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8640847&form=6&db=m Characterisation of the complement-regulatory proteins decay-accelerating factor (DAF, CD55) and membrane cofactor protein (MCP, CD46) on a human colonic adenocarcinoma cell line. ongoing research,unassigned 4,0 3.4.21.47 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6538270&form=6&db=m HLA-linked complement markers in Alzheimer's and Parkinson's disease: C4 variant (C4B2) a possible marker for senile dementia of the Alzheimer type. diagnostic usage,ongoing research,unassigned 3,3,0 3.4.21.47 Arthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3462903&form=6&db=m Genetic markers in rheumatoid arthritis. causal interaction,unassigned 4,0 3.4.21.47 Arthritis, Juvenile http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3861185&form=6&db=m [Genetic study of properdin factor B in juvenile rheumatoid arthritis] unassigned - 3.4.21.47 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=808229&form=6&db=m Depressed synovial fluid levels of properdin and properdin factor B in patients with rheumatoid arthritis. diagnostic usage,unassigned 3,0 3.4.21.47 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=849359&form=6&db=m Correlation between levels of breakdown products of C3, C4, and properdin factor B in synovial fluids from patients with rheumatoid arthritis. causal interaction,diagnostic usage,unassigned 3,3,0 3.4.21.47 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1563983&form=6&db=m Properdin factor B and complement factor C4 allotypes in rheumatoid arthritis: results of a follow-up study. causal interaction,ongoing research,unassigned 2,1,0 3.4.21.47 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3495479&form=6&db=m Bf and C3 polymorphisms in rheumatoid arthritis. unassigned - 3.4.21.47 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3876434&form=6&db=m Genetic variants of properdin factor B (Bf) in rheumatoid arthritis. causal interaction,ongoing research,unassigned 2,1,0 3.4.21.47 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=309715&form=6&db=m T and B lymphocytes, immunoglobulins and complement components in bronchial asthma. unassigned - 3.4.21.47 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=872357&form=6&db=m Inactivation of heamolytic complement by house dust allergen in the serum of children with atopic diseases. causal interaction,diagnostic usage,unassigned 2,2,0 3.4.21.47 Atypical Hemolytic Uremic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28637873&form=6&db=m Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation. ongoing research,unassigned 2,0 3.4.21.47 Atypical Hemolytic Uremic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29370420&form=6&db=m C3 glomerulonephritis secondary to mutations in factors H and I: rapid recurrence in deceased donor kidney transplant effectively treated with eculizumab. causal interaction,unassigned 4,0 3.4.21.47 Bacteremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=47148&form=6&db=m Activation of the properdin pathway of complement in patients with gram-negative of bacteremia. causal interaction,diagnostic usage,unassigned 3,4,0 3.4.21.47 Bacterial Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7258825&form=6&db=m The role of immune complexes in the pathogenesis of pleural effusions. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,1,0 3.4.21.47 Caplan Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6577907&form=6&db=m HLA-A, B and DR antigens and properdin factor B allotypes in Caplan's syndrome. unassigned - 3.4.21.47 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13921595&form=6&db=m Further studies on cytolysis of Ehrlich ascites tumor cells brought into contact with normal human serum. The nature of the heat-labile factor. diagnostic usage,ongoing research,unassigned 3,4,0 3.4.21.47 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=427802&form=6&db=m Soluble factors from liver and hepatomas which inhibit [3H]thymidine incorporation into DNA of Novikoff hepatoma cells. causal interaction,unassigned 1,0 3.4.21.47 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1700167&form=6&db=m [A clinical study of complements as a marker of a hepatocellular carcinoma] diagnostic usage,unassigned 2,0 3.4.21.47 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2454720&form=6&db=m Complements as new diagnostic tools of hepatocellular carcinoma in cirrhotic patients. diagnostic usage,unassigned 4,0 3.4.21.47 Celiac Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6901543&form=6&db=m Properdin factor B and glyoxalase 1 polymorphism in celiac disease. diagnostic usage,ongoing research,unassigned 3,2,0 3.4.21.47 Colitis, Ulcerative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=604196&form=6&db=m Humoral immune system in inflammatory bowel disease: I. Complement levels. unassigned - 3.4.21.47 Colitis, Ulcerative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6450718&form=6&db=m Complement inhibitors and immunoconglutinins in ulcerative colitis and Crohn's disease. diagnostic usage,unassigned 2,0 3.4.21.47 Connective Tissue Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7258825&form=6&db=m The role of immune complexes in the pathogenesis of pleural effusions. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,1,0 3.4.21.47 Crohn Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=604196&form=6&db=m Humoral immune system in inflammatory bowel disease: I. Complement levels. unassigned - 3.4.21.47 Crohn Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6450718&form=6&db=m Complement inhibitors and immunoconglutinins in ulcerative colitis and Crohn's disease. diagnostic usage,unassigned 2,0 3.4.21.47 Dermatitis, Atopic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=872357&form=6&db=m Inactivation of heamolytic complement by house dust allergen in the serum of children with atopic diseases. causal interaction,diagnostic usage,unassigned 2,2,0 3.4.21.47 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=478186&form=6&db=m Genetic susceptibility to diabetes mellitus: the distribution of properdin factor B (Bf) and glyoxalase (GLO) phenotypes. diagnostic usage,unassigned 3,0 3.4.21.47 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3644938&form=6&db=m Genetic polymorphism of properdin factor B (BF) in Chinese patients with two types of diabetes mellitus. diagnostic usage,ongoing research,unassigned 3,2,0 3.4.21.47 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6594040&form=6&db=m Genetic heterogeneity of insulin-dependent (type I) diabetes mellitus: evidence from a study of extended haplotypes. therapeutic application,unassigned 1,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=87677&form=6&db=m Genetic marker for insulin-dependent diabetes mellitus. unassigned - 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=89438&form=6&db=m Insulin-dependent diabetes mellitus and properdin factor B. diagnostic usage,ongoing research,unassigned 3,3,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2340795&form=6&db=m Immunogenetics of early-onset insulin-dependent diabetes mellitus among the Japanese: HLA, Gm, BF, GLO, and organ-specific autoantibodies--the J.D.S. study. diagnostic usage,ongoing research,unassigned 2,4,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6117683&form=6&db=m Close genetic linkage between diabetes mellitus and kidd blood group. diagnostic usage,unassigned 4,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6416912&form=6&db=m Association studies between Type 1 (insulin-dependent) diabetes and 27 genetic markers: lack of association between Type 1 diabetes and Kidd blood group. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,3,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6580815&form=6&db=m The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity. diagnostic usage,therapeutic application,unassigned 2,1,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6952765&form=6&db=m The HLAB*18,BF*F1 in haplotype in type 1 diabetes. diagnostic usage,ongoing research,unassigned 4,4,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7009418&form=6&db=m BF types and the mode of inheritance of insulin-dependent diabetes mellitus (IDDM). unassigned - 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7014302&form=6&db=m Lymphocytotoxic antibodies and histocompatibility antigens in juvenile-onset diabetes mellitus. causal interaction,diagnostic usage,unassigned 3,1,0 3.4.21.47 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7859638&form=6&db=m A multicenter study on HLA and autoimmunity in Japanese patients with early-onset insulin-dependent diabetes mellitus (IDDM): the JDS Study. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,3,0 3.4.21.47 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22338105&form=6&db=m Elevated Properdin and Enhanced Complement Activation in First-Degree Relatives of South Asian Subjects With Type 2 Diabetes. causal interaction,ongoing research,unassigned 3,1,0 3.4.21.47 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=49134&form=6&db=m A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura. diagnostic usage,unassigned 4,0 3.4.21.47 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2394034&form=6&db=m Human anti-idiotypic antibody responses to autoantibody against the alternative pathway C3 convertase. diagnostic usage,ongoing research,therapeutic application,unassigned 4,3,1,0 3.4.21.47 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4630981&form=6&db=m Properdin anc C3 proactivator: alternate pathway components in human glomerulonephritis. unassigned - 3.4.21.47 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6553695&form=6&db=m An inherited defect in the C3 convertase, C3b,Bb, associated with glomerulonephritis. unassigned - 3.4.21.47 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19190809&form=6&db=m Hereditary and acquired complement dysregulation in membranoproliferative glomerulonephritis. unassigned - 3.4.21.47 Glomerulonephritis, IGA http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3272818&form=6&db=m Factor B subtypes in Japanese patients with IgA nephropathy and with idiopathic membranous nephropathy. ongoing research,unassigned 2,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1141431&form=6&db=m Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis. diagnostic usage,unassigned 4,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1149337&form=6&db=m Clearances of complement components, C3 proactivator and other serum proteins in chronic membranoproliferative glomerulonephritis (CMPGN). diagnostic usage,unassigned 2,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1541054&form=6&db=m Study of the idiotypic response to autoantibody to the alternative pathway C3/C5 convertase in normal individuals, patients with membranoproliferative glomerulonephritis, and experimental animals. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1697516&form=6&db=m Production of IgG and IgM autoantibody to the alternative pathway C3 convertase in normal individuals and patients with membranoproliferative glomerulonephritis. diagnostic usage,unassigned 2,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2143128&form=6&db=m Two types of C3 nephritic factor: properdin-dependent C3NeF and properdin-independent C3NeF. causal interaction,diagnostic usage,therapeutic application,unassigned 2,1,1,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2329415&form=6&db=m Autoantibody to complement neoantigens in membranoproliferative glomerulonephritis. ongoing research,unassigned 4,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2394034&form=6&db=m Human anti-idiotypic antibody responses to autoantibody against the alternative pathway C3 convertase. diagnostic usage,ongoing research,therapeutic application,unassigned 4,3,1,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4094159&form=6&db=m [Direct detection C3bBb stabilizing activity in sera from hypocomplementaemic membranoproliferative glomerulonephritis (MPGN) and complement profiles of C3NeF positive cases] diagnostic usage,ongoing research,unassigned 3,1,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7151338&form=6&db=m Biological significance of the C3 nephritic factor in membranoproliferative glomerulonephritis. diagnostic usage,ongoing research,unassigned 2,1,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7970124&form=6&db=m Selective disappearance of C3NeF IgG autoantibody in the plasma of a patient with membranoproliferative glomerulonephritis following renal transplantation. diagnostic usage,unassigned 2,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8395463&form=6&db=m Nucleotide sequence of a human autoantibody to the alternative pathway C3/C5 convertase (C3NeF). unassigned - 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8445254&form=6&db=m A novel ELISA assay for the detection of C3 nephritic factor. ongoing research,unassigned 3,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17024390&form=6&db=m MPGN II--genetically determined by defective complement regulation? causal interaction,unassigned 1,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19190809&form=6&db=m Hereditary and acquired complement dysregulation in membranoproliferative glomerulonephritis. unassigned - 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19640589&form=6&db=m Autoimmune forms of thrombotic microangiopathy and membranoproliferative glomerulonephritis: Indications for a disease spectrum and common pathogenic principles. unassigned - 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30929851&form=6&db=m C5 Convertase Blockade in Membranoproliferative Glomerulonephritis: A Single-Arm Clinical Trial. diagnostic usage,ongoing research,therapeutic application,unassigned 1,3,2,0 3.4.21.47 Glomerulonephritis, Membranoproliferative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32050203&form=6&db=m Morphofunctional Effects of C5 Convertase Blockade in Immune Complex-Mediated Membranoproliferative Glomerulonephritis: Report of Two Cases with Evidence of Terminal Complement Activation. unassigned - 3.4.21.47 Glomerulonephritis, Membranous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3272818&form=6&db=m Factor B subtypes in Japanese patients with IgA nephropathy and with idiopathic membranous nephropathy. ongoing research,unassigned 2,0 3.4.21.47 Glomerulonephritis, Membranous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6905503&form=6&db=m Properdin factor B alleles in patients with idiopathic membranous nephropathy. therapeutic application,unassigned 1,0 3.4.21.47 Glucose Intolerance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22338105&form=6&db=m Elevated Properdin and Enhanced Complement Activation in First-Degree Relatives of South Asian Subjects With Type 2 Diabetes. causal interaction,ongoing research,unassigned 3,1,0 3.4.21.47 Graves Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6572032&form=6&db=m Properdin factor B (Bf) and glyoxalase in Graves' disease. diagnostic usage,ongoing research,unassigned 1,1,0 3.4.21.47 Guillain-Barre Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6920298&form=6&db=m Complement factors and acute phase reactants in the Guillain-Barré syndrome. diagnostic usage,ongoing research,unassigned 3,1,0 3.4.21.47 Hemoglobinuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2956607&form=6&db=m Regulation of the activity of platelet-bound C3 convertase of the alternative pathway of complement by platelet factor H. ongoing research,unassigned 1,0 3.4.21.47 Hemoglobinuria, Paroxysmal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2956607&form=6&db=m Regulation of the activity of platelet-bound C3 convertase of the alternative pathway of complement by platelet factor H. ongoing research,unassigned 1,0 3.4.21.47 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7948818&form=6&db=m Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,3,0 3.4.21.47 Hereditary Complement Deficiency Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18667363&form=6&db=m Serum bactericidal activity against Neisseria meningitidis in patients with C3 nephritic factors is dependent on IgG allotypes. causal interaction,unassigned 3,0 3.4.21.47 HIV Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1823312&form=6&db=m Bf S gene frequency in Nigerians with HIV infection. causal interaction,diagnostic usage,unassigned 4,2,0 3.4.21.47 Hodgkin Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1791312&form=6&db=m Serum levels of ceruloplasmin, properdin factor B and copper in lymphoma patients. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 3.4.21.47 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=872357&form=6&db=m Inactivation of heamolytic complement by house dust allergen in the serum of children with atopic diseases. causal interaction,diagnostic usage,unassigned 2,2,0 3.4.21.47 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2364549&form=6&db=m The complements and immunoglobulins in different media of healthy pregnant women and in pregnant women with increased blood pressure. diagnostic usage,unassigned 1,0 3.4.21.47 IgA Vasculitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=49134&form=6&db=m A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura. diagnostic usage,unassigned 4,0 3.4.21.47 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=458893&form=6&db=m Fresh-frozen plasma vs. plasma protein derivative as adjunctive therapy for patients with massive burns. therapeutic application,unassigned 2,0 3.4.21.47 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=793541&form=6&db=m Consumptive opsoninopathy: possible pathogenesis in lethal and opportunistic infections. diagnostic usage,unassigned 3,0 3.4.21.47 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19660812&form=6&db=m Stringent regulation of complement lectin pathway C3/C5 convertase by C4b-binding protein (C4BP). unassigned - 3.4.21.47 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20837143&form=6&db=m Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway. causal interaction,therapeutic application,unassigned 4,1,0 3.4.21.47 Inflammatory Bowel Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2509&form=6&db=m The alternate complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein. unassigned - 3.4.21.47 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19871167&form=6&db=m THE QUANTITATIVE DETERMINATION OF INFLUENZA VIRUS AND ANTIBODIES BY MEANS OF RED CELL AGGLUTINATION. ongoing research,unassigned 2,0 3.4.21.47 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22338105&form=6&db=m Elevated Properdin and Enhanced Complement Activation in First-Degree Relatives of South Asian Subjects With Type 2 Diabetes. causal interaction,ongoing research,unassigned 3,1,0 3.4.21.47 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26895476&form=6&db=m Complement gene variants determine the risk of immunoglobulin-associated MPGN and C3 glomerulopathy and predict long-term renal outcome. causal interaction,unassigned 3,0 3.4.21.47 Lichen Sclerosus et Atrophicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6554993&form=6&db=m HLA antigens and Bf allotypes in lichen sclerosus et atrophicus. therapeutic application,unassigned 1,0 3.4.21.47 Lipodystrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=845257&form=6&db=m Metabolism of the fifth component of complement, and its relation to metabolism of the third component, in patients with complement activation. diagnostic usage,unassigned 1,0 3.4.21.47 Lipodystrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2143128&form=6&db=m Two types of C3 nephritic factor: properdin-dependent C3NeF and properdin-independent C3NeF. causal interaction,diagnostic usage,therapeutic application,unassigned 2,1,1,0 3.4.21.47 Liver Cirrhosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1141431&form=6&db=m Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis. diagnostic usage,unassigned 4,0 3.4.21.47 Liver Cirrhosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1700167&form=6&db=m [A clinical study of complements as a marker of a hepatocellular carcinoma] diagnostic usage,unassigned 2,0 3.4.21.47 Liver Cirrhosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2454720&form=6&db=m Complements as new diagnostic tools of hepatocellular carcinoma in cirrhotic patients. diagnostic usage,unassigned 4,0 3.4.21.47 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2791806&form=6&db=m Role of serum complement, immunoglobulins, and cell-mediated immune system in the pathogenesis of spontaneous bacterial peritonitis (SBP). diagnostic usage,ongoing research,unassigned 4,4,0 3.4.21.47 Liver Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7948818&form=6&db=m Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,3,0 3.4.21.47 Liver Failure, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7948818&form=6&db=m Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,3,0 3.4.21.47 Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14672751&form=6&db=m Effect of complement fragment 1 esterase inhibition on survival of human decay-accelerating factor pig lungs perfused with human blood. unassigned - 3.4.21.47 Lupus Erythematosus, Systemic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=49134&form=6&db=m A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura. diagnostic usage,unassigned 4,0 3.4.21.47 Lupus Erythematosus, Systemic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1096924&form=6&db=m Dermal-epidermal deposition of complement components and properdin in systemic lupus erythematosus. diagnostic usage,ongoing research,unassigned 3,2,0 3.4.21.47 Lupus Erythematosus, Systemic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3159752&form=6&db=m A circulating inhibitor of fluid-phase amplification. C3 convertase formation in systemic lupus erythematosus. diagnostic usage,therapeutic application,unassigned 4,2,0 3.4.21.47 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1791312&form=6&db=m Serum levels of ceruloplasmin, properdin factor B and copper in lymphoma patients. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 3.4.21.47 Lymphoma, Non-Hodgkin http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1791312&form=6&db=m Serum levels of ceruloplasmin, properdin factor B and copper in lymphoma patients. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 3.4.21.47 Malaria, Cerebral http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22689574&form=6&db=m The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria. therapeutic application,unassigned 1,0 3.4.21.47 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=593653&form=6&db=m Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes. unassigned - 3.4.21.47 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6917774&form=6&db=m Associations of properdin factor B with melanoma. diagnostic usage,ongoing research,unassigned 3,4,0 3.4.21.47 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6950410&form=6&db=m Induction of immune cytolysis: tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase. unassigned - 3.4.21.47 Meningococcal Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18667363&form=6&db=m Serum bactericidal activity against Neisseria meningitidis in patients with C3 nephritic factors is dependent on IgG allotypes. causal interaction,unassigned 3,0 3.4.21.47 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=91230&form=6&db=m Strong linkage disequilibrium between HLA-Dw2 and and BfS in multiple sclerosis and in the normal population. unassigned - 3.4.21.47 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=973802&form=6&db=m Disease markers in acute multiple sclerosis. causal interaction,diagnostic usage,unassigned 4,2,0 3.4.21.47 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6558078&form=6&db=m HLA-Dw1 and BfF as protective markers in multiple sclerosis. diagnostic usage,ongoing research,unassigned 2,2,0 3.4.21.47 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3916662&form=6&db=m Complement and cancer: activation of the alternative pathway as a theoretical base for immunotherapy. unassigned - 3.4.21.47 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13921595&form=6&db=m Further studies on cytolysis of Ehrlich ascites tumor cells brought into contact with normal human serum. The nature of the heat-labile factor. diagnostic usage,ongoing research,unassigned 3,4,0 3.4.21.47 Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=49134&form=6&db=m A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura. diagnostic usage,unassigned 4,0 3.4.21.47 Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=845257&form=6&db=m Metabolism of the fifth component of complement, and its relation to metabolism of the third component, in patients with complement activation. diagnostic usage,unassigned 1,0 3.4.21.47 Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1141431&form=6&db=m Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis. diagnostic usage,unassigned 4,0 3.4.21.47 Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4693654&form=6&db=m Hypocomplementemia of membranoproliferative nephritis. Dependence of the nephritic factor reaction on properdin factor B. diagnostic usage,unassigned 1,0 3.4.21.47 Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10412868&form=6&db=m The alternative pathway C3 convertase and glomerular deposits. unassigned - 3.4.21.47 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=49134&form=6&db=m A study of complement components C3, C5, C6, C7, C8 and C9 in chronic membranoproliferative glomerulonephritis, systemic lupus erythematosus, poststreptococcal nephritis, idiopathic nephrotic syndrome and anaphylactoid purpura. diagnostic usage,unassigned 4,0 3.4.21.47 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3877619&form=6&db=m T-cell subsets and response to mitogens in patients with steroid responsive nephrotic syndrome. ongoing research,therapeutic application,unassigned 1,1,0 3.4.21.47 Osteoarthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=849359&form=6&db=m Correlation between levels of breakdown products of C3, C4, and properdin factor B in synovial fluids from patients with rheumatoid arthritis. causal interaction,diagnostic usage,unassigned 3,3,0 3.4.21.47 Otitis Media http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=143103&form=6&db=m Chronic serous otitis media: an immune complex disease. unassigned - 3.4.21.47 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6538270&form=6&db=m HLA-linked complement markers in Alzheimer's and Parkinson's disease: C4 variant (C4B2) a possible marker for senile dementia of the Alzheimer type. diagnostic usage,ongoing research,unassigned 3,3,0 3.4.21.47 Periodontal Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=338883&form=6&db=m Gingival fluid and serum in periodontal diseases. II. Evidence for cleavage of complement components C3, C3 proactivator (factor B) and C4 in gingival fluid. diagnostic usage,unassigned 1,0 3.4.21.47 Periodontal Pocket http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=338883&form=6&db=m Gingival fluid and serum in periodontal diseases. II. Evidence for cleavage of complement components C3, C3 proactivator (factor B) and C4 in gingival fluid. diagnostic usage,unassigned 1,0 3.4.21.47 Periodontitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3641478&form=6&db=m Association between HLA-A9 and rapidly progressive periodontitis. diagnostic usage,ongoing research,unassigned 3,1,0 3.4.21.47 Pleural Effusion http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6603298&form=6&db=m High levels of complement breakdown products in tuberculous pleural effusions. causal interaction,diagnostic usage,unassigned 1,4,0 3.4.21.47 Pleuropneumonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3592376&form=6&db=m Role of haemophilus pleuropneumoniae lipopolysaccharide endotoxin in the pathogenesis of porcine Haemophilus pleuropneumonia. causal interaction,therapeutic application,unassigned 3,1,0 3.4.21.47 Pneumococcal Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1279001&form=6&db=m Complement system in pneumococcal infections. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 3.4.21.47 Postpartum Thyroiditis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8640296&form=6&db=m Major histocompatibility complex class II and complement polymorphisms in postpartum thyroiditis. ongoing research,unassigned 2,0 3.4.21.47 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6103487&form=6&db=m Properdin factor B alleles in pre-eclampsia. unassigned - 3.4.21.47 Precursor Cell Lymphoblastic Leukemia-Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6958349&form=6&db=m Properdin factor B and acute lymphocytic leukemia (ALL). diagnostic usage,ongoing research,unassigned 1,3,0 3.4.21.47 Psoriasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3312341&form=6&db=m Properdin factor B allotypes in Japanese patients with psoriasis. diagnostic usage,ongoing research,unassigned 2,4,0 3.4.21.47 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22903675&form=6&db=m How immune complexes from certain IgG NAbs and any F(ab')? can mediate excessive complement activation. unassigned - 3.4.21.47 Spinocerebellar Degenerations http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6937161&form=6&db=m Hereditary ataxia and the sixth chromosome. diagnostic usage,ongoing research,unassigned 2,3,0 3.4.21.47 Urogenital Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6156074&form=6&db=m Transferrin, C3 complement, haptoglobin, plasminogen and alpha 2-microglobulin in patients with urogenital tumors. causal interaction,diagnostic usage,unassigned 2,2,0 3.4.21.47 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7005726&form=6&db=m [Significance of immunocomplexes and complement in renal transplantation. Preliminary data] causal interaction,unassigned 3,0 3.4.21.47 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7948818&form=6&db=m Role of fibronectin and complement in immunopathogenesis of acute and subacute hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,3,0 3.4.21.47 Whooping Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1951767&form=6&db=m Oxygen pressure-dependent control of carbonic anhydrase synthesis in chick embryonic erythrocytes. ongoing research,unassigned 1,0 3.4.21.47 Xanthomatosis, Cerebrotendinous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6574616&form=6&db=m Study of a family with Cerebrotendinous Xanthomatosis. No HLA linkage, but an informative recombination between HLA-B and Bf. ongoing research,unassigned 2,0