3.3.2.6 Aberrant Crypt Foci http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14690793&form=6&db=m Effects of green tea and high-fat diet on arachidonic acid metabolism and aberrant crypt foci formation in an azoxymethane-induced colon carcinogenesis mouse model. causal interaction,unassigned 3,0 3.3.2.6 Acne Vulgaris http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33592148&form=6&db=m Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 Acute Coronary Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19578513&form=6&db=m Biomarkers and Bioassays for Cardiovascular Diseases: Present and Future. causal interaction,diagnostic usage,therapeutic application,unassigned 2,1,1,0 3.3.2.6 Acute Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15805137&form=6&db=m Nuclear localization of leukotriene A4 hydrolase in type II alveolar epithelial cells in normal and fibrotic lung. causal interaction,ongoing research,unassigned 4,4,0 3.3.2.6 Acute Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27126280&form=6&db=m Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H. therapeutic application,unassigned 1,0 3.3.2.6 Acute Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28218840&form=6&db=m Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis. causal interaction,therapeutic application,unassigned 4,1,0 3.3.2.6 Acute Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32679453&form=6&db=m Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury. causal interaction,therapeutic application,unassigned 3,3,0 3.3.2.6 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12865451&form=6&db=m Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 3.3.2.6 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15134534&form=6&db=m Leukotriene A4 hydrolase as a target for cancer prevention and therapy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 3.3.2.6 Anthrax http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8973585&form=6&db=m The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by leukotriene A4 hydrolase and metallopeptidase inhibitors. causal interaction,ongoing research,therapeutic application,unassigned 2,3,1,0 3.3.2.6 Arthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24701582&form=6&db=m The Interrelationship between Leukotriene B4 and Leukotriene-A4-Hydrolase in Collagen/Adjuvant-Induced Arthritis in Rats. ongoing research,unassigned 2,0 3.3.2.6 Aspergillosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30745237&form=6&db=m Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase. therapeutic application,unassigned 1,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11069563&form=6&db=m Studies on linkage and association of atopy with the chromosomal region 12q13-24. unassigned - 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15715933&form=6&db=m Changes of 5-lipoxygenase pathway and proinflammatory mediators in cerebral cortex and lung tissue of sensitized rats. causal interaction,ongoing research,unassigned 1,1,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18547289&form=6&db=m The role of LTA4H and ALOX5AP polymorphism in asthma and allergy susceptibility. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19876785&form=6&db=m Modulation of inflammatory disease by inhibitors of leukotriene A4 hydrolase. causal interaction,unassigned 3,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20067482&form=6&db=m The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,1,1 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20810156&form=6&db=m ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. diagnostic usage,ongoing research,therapeutic application,unassigned 1,3,1,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23167751&form=6&db=m Leukotriene B4 receptor locus gene characterisation and association studies in asthma. causal interaction,unassigned 4,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23831697&form=6&db=m Quantitation of leukotriene B(4) in human sputum as a biomarker using UPLC-MS/MS. ongoing research,therapeutic application,unassigned 2,4,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25018015&form=6&db=m Effects of JNJ-40929837, a leukotriene A4 hydrolase inhibitor, in a bronchial allergen challenge model of asthma. ongoing research,therapeutic application,unassigned 2,2,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29749828&form=6&db=m Candidate gene analysis of asthma in a population of Arab descent: a case-control study in Jordan. diagnostic usage,unassigned 2,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30135247&form=6&db=m An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30352167&form=6&db=m Leukotriene A4 Hydrolase Activation and Leukotriene B4 Production by Eosinophils in Severe Asthma. unassigned - 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30433812&form=6&db=m Eosinophils Express LTA4 Hydrolase and Synthesize LTB4; Important for Asthma Pathogenesis? therapeutic application,unassigned 1,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31178722&form=6&db=m Pharmacogenetic Factors Affecting Asthma Treatment Response. Potential Implications for Drug Therapy. therapeutic application,unassigned 1,0 3.3.2.6 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32185106&form=6&db=m Molecular docking and network connections of active compounds from the classical herbal formula Ding Chuan Tang. causal interaction,therapeutic application,unassigned 2,1,0 3.3.2.6 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16698924&form=6&db=m Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19130089&form=6&db=m Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. causal interaction,ongoing research,unassigned 4,2,0 3.3.2.6 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23153620&form=6&db=m Leukotriene A4 hydrolase haplotype, diet and atherosclerosis: a twin study. ongoing research,therapeutic application,unassigned 2,1,0 3.3.2.6 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25721704&form=6&db=m Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: The Athero-Express Genomics Study. causal interaction,unassigned 3,0 3.3.2.6 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26714527&form=6&db=m [Study on the association between leukotriene A4 hydrolase gene polymorphism and ischemic stroke]. diagnostic usage,ongoing research,unassigned 3,1,0 3.3.2.6 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29413439&form=6&db=m Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis: Integrated Quantification of Plaque Inflammation, Permeability, and Burden During Treatment With a Leukotriene A4 Hydrolase Inhibitor. ongoing research,therapeutic application,unassigned 1,4,0 3.3.2.6 Blister http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33047366&form=6&db=m Distinct compartmentalization of immune cells and mediators characterizes bullous pemphigoid disease. unassigned - 3.3.2.6 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12865451&form=6&db=m Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 3.3.2.6 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15134534&form=6&db=m Leukotriene A4 hydrolase as a target for cancer prevention and therapy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 3.3.2.6 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16632477&form=6&db=m Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors. causal interaction,ongoing research,therapeutic application,unassigned 3,1,3,0 3.3.2.6 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28575166&form=6&db=m LTA4H regulates cell cycle and skin carcinogenesis. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,2,4 3.3.2.6 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34051272&form=6&db=m Bestatin Cream Impairs Solar Simulated Light?Driven Skin Inflammation and Skin Carcinogenesis in Mice. causal interaction,ongoing research,unassigned 2,4,0 3.3.2.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31287215&form=6&db=m Mass Spectrometric Analysis Identifies AIMP1 and LTA4H as FSCN1-Binding Proteins in Laryngeal Squamous Cell Carcinoma. diagnostic usage,unassigned 2,0 3.3.2.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34051272&form=6&db=m Bestatin Cream Impairs Solar Simulated Light?Driven Skin Inflammation and Skin Carcinogenesis in Mice. causal interaction,ongoing research,unassigned 2,4,0 3.3.2.6 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34051272&form=6&db=m Bestatin Cream Impairs Solar Simulated Light?Driven Skin Inflammation and Skin Carcinogenesis in Mice. causal interaction,ongoing research,unassigned 2,4,0 3.3.2.6 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18323512&form=6&db=m Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations. causal interaction,unassigned 4,0 3.3.2.6 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19130089&form=6&db=m Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. causal interaction,ongoing research,unassigned 4,2,0 3.3.2.6 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19876785&form=6&db=m Modulation of inflammatory disease by inhibitors of leukotriene A4 hydrolase. causal interaction,unassigned 3,0 3.3.2.6 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24366255&form=6&db=m Expression Analysis of Leukotriene-Inflammatory Gene Interaction Network in Patients with Coronary Artery Disease. causal interaction,diagnostic usage,unassigned 4,2,0 3.3.2.6 Chemical and Drug Induced Liver Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30363837&form=6&db=m Adjunctive dexamethasone for the treatment of HIV-uninfected adults with tuberculous meningitis stratified by Leukotriene A4 hydrolase genotype (LAST ACT): Study protocol for a randomised double blind placebo controlled non-inferiority trial. causal interaction,therapeutic application,unassigned 1,4,0 3.3.2.6 Coinfection http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8269937&form=6&db=m Coupling of recombinant 5-lipoxygenase and leukotriene A4 hydrolase activities and transcellular metabolism of leukotriene A4 in Sf9 insect cells. ongoing research,therapeutic application,unassigned 4,1,0 3.3.2.6 Colitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18157165&form=6&db=m Attenuation of inflammation and cytokine production in rat colitis by a novel selective inhibitor of leukotriene A4 hydrolase. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 Colitis, Ulcerative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33592148&form=6&db=m Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19531649&form=6&db=m [6]-Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase. causal interaction,therapeutic application,unassigned 1,4,0 3.3.2.6 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28065501&form=6&db=m Synthesis, docking, cytotoxicity, and LTA4H inhibitory activity of new gingerol derivatives as potential colorectal cancer therapy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,3 3.3.2.6 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28065501&form=6&db=m Synthesis, docking, cytotoxicity, and LTA4H inhibitory activity of new gingerol derivatives as potential colorectal cancer therapy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,3 3.3.2.6 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31085102&form=6&db=m Inhibition of LTA4H by bestatin in human and mouse colorectal cancer. causal interaction,ongoing research,unassigned 3,3,0 3.3.2.6 Coronary Artery Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19130089&form=6&db=m Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. causal interaction,ongoing research,unassigned 4,2,0 3.3.2.6 Crohn Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31093505&form=6&db=m The Polymorphism rs17525495 of LTA4H Is Associated with Susceptibility of Crohn's Disease instead of Intestinal Tuberculosis in a Chinese Han Population. diagnostic usage,unassigned 3,0 3.3.2.6 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27806191&form=6&db=m Phase I Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis. ongoing research,unassigned 4,0 3.3.2.6 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34538755&form=6&db=m Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis. ongoing research,therapeutic application,unassigned 3,4,0 3.3.2.6 Dermatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9617756&form=6&db=m Effects of SA6541, a leukotriene A4 hydrolase inhibitor, and indomethacin on carrageenan-induced murine dermatitis. ongoing research,therapeutic application,unassigned 4,4,0 3.3.2.6 Dermatitis, Allergic Contact http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33037399&form=6&db=m Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation. ongoing research,therapeutic application,unassigned 2,1,0 3.3.2.6 Dermatitis, Atopic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8967787&form=6&db=m Leukotriene A4 hydrolase in peripheral leukocytes of patients with atopic dermatitis. causal interaction,diagnostic usage,therapeutic application,unassigned 4,2,1,0 3.3.2.6 Dermatitis, Contact http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25959240&form=6&db=m Leukotriene B?-leukotriene B? receptor axis promotes oxazolone-induced contact dermatitis by directing skin homing of neutrophils and CD8? T cells. ongoing research,unassigned 1,0 3.3.2.6 Gastroesophageal Reflux http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22777338&form=6&db=m Diagnostic Utility of Major Basic Protein, Eotaxin-3, and Leukotriene Enzyme Staining in Eosinophilic Esophagitis. diagnostic usage,therapeutic application,unassigned 4,1,0 3.3.2.6 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19919819&form=6&db=m 5-lipoxygenase pathway promotes cell proliferation in human glioma cell lines. causal interaction,ongoing research,therapeutic application,unassigned 3,4,2,0 3.3.2.6 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10337029&form=6&db=m Gene expression of 5-lipoxygenase and LTA4 hydrolase in renal tissue of nephrotic syndrome patients. diagnostic usage,ongoing research,unassigned 1,4,0 3.3.2.6 Hidradenitis Suppurativa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33592148&form=6&db=m Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 HIV Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28419368&form=6&db=m Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,3,0 3.3.2.6 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25902778&form=6&db=m Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk. causal interaction,diagnostic usage,unassigned 4,2,0 3.3.2.6 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18547289&form=6&db=m The role of LTA4H and ALOX5AP polymorphism in asthma and allergy susceptibility. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2 3.3.2.6 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23986401&form=6&db=m Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension. causal interaction,unassigned 4,0 3.3.2.6 Idiopathic Pulmonary Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15805137&form=6&db=m Nuclear localization of leukotriene A4 hydrolase in type II alveolar epithelial cells in normal and fibrotic lung. causal interaction,ongoing research,unassigned 4,4,0 3.3.2.6 Idiopathic Pulmonary Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28218840&form=6&db=m Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis. causal interaction,therapeutic application,unassigned 4,1,0 3.3.2.6 Idiopathic Pulmonary Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32679453&form=6&db=m Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury. causal interaction,therapeutic application,unassigned 3,3,0 3.3.2.6 Immune Reconstitution Inflammatory Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27643598&form=6&db=m Role of LTA4H Polymorphism in Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome Occurrence and Clinical Severity in Patients Infected with HIV. causal interaction,ongoing research,unassigned 1,2,0 3.3.2.6 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20211140&form=6&db=m The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. causal interaction,therapeutic application,unassigned 4,1,0 3.3.2.6 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20227659&form=6&db=m Mycobacterial infections and the inflammatory seesaw. unassigned - 3.3.2.6 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21112816&form=6&db=m Association analysis of the LTA4H gene polymorphisms and pulmonary tuberculosis in 9115 subjects. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,4,2 3.3.2.6 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28658259&form=6&db=m Neutrophil derived LTB4 induces macrophage aggregation in response to encapsulated Streptococcus iniae infection. unassigned - 3.3.2.6 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30745237&form=6&db=m Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase. therapeutic application,unassigned 1,0 3.3.2.6 Inflammatory Bowel Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17230539&form=6&db=m Colonic expression of leukotriene-pathway enzymes in inflammatory bowel diseases. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,2,0 3.3.2.6 Inflammatory Bowel Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18157165&form=6&db=m Attenuation of inflammation and cytokine production in rat colitis by a novel selective inhibitor of leukotriene A4 hydrolase. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 Ischemic Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18323512&form=6&db=m Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations. causal interaction,unassigned 4,0 3.3.2.6 Ischemic Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25215090&form=6&db=m Association of ALOX5, LTA4H and LTC4S gene polymorphisms with ischemic stroke risk in a cohort of Chinese in east China. causal interaction,ongoing research,unassigned 4,2,0 3.3.2.6 Ischemic Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26714527&form=6&db=m [Study on the association between leukotriene A4 hydrolase gene polymorphism and ischemic stroke]. diagnostic usage,ongoing research,unassigned 3,1,0 3.3.2.6 Leprosy, Multibacillary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20211140&form=6&db=m The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. causal interaction,therapeutic application,unassigned 4,1,0 3.3.2.6 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8630722&form=6&db=m Inhibition of leukotriene synthesis by azelastine. ongoing research,unassigned 4,0 3.3.2.6 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11451962&form=6&db=m Co-localization of leukotriene a4 hydrolase with 5-lipoxygenase in nuclei of alveolar macrophages and rat basophilic leukemia cells but not neutrophils. ongoing research,unassigned 2,0 3.3.2.6 leukotriene-a4 hydrolase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32844470&form=6&db=m Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis. causal interaction,unassigned 4,0 3.3.2.6 Lung Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25636538&form=6&db=m MMP generated matrikines. causal interaction,unassigned 4,0 3.3.2.6 Lung Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27730172&form=6&db=m Genetic regulation of expression of leukotriene A4 hydrolase. causal interaction,therapeutic application,unassigned 4,3,0 3.3.2.6 Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29180335&form=6&db=m [Pathogenic role of leukotriene B4 in pulmonary microvascular endothelial cell hyper- permeability induced by one lung ventilation in rabbits]. therapeutic application,unassigned 1,0 3.3.2.6 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8918363&form=6&db=m Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,3 3.3.2.6 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26959888&form=6&db=m Germline genetics of cancer of unknown primary (CUP) and its specific subtypes. unassigned - 3.3.2.6 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9209681&form=6&db=m Human melanoma cells generate leukotrienes B4 and C4 from leukotriene A4. diagnostic usage,ongoing research,unassigned 3,4,0 3.3.2.6 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24653816&form=6&db=m Tissue-based microarray expression of genes predictive of metastasis in uveal melanoma and differentially expressed in metastatic uveal melanoma. causal interaction,diagnostic usage,unassigned 1,3,0 3.3.2.6 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28074614&form=6&db=m Mutation analysis and gene expression profiling of ocular melanomas in cats. causal interaction,unassigned 3,0 3.3.2.6 Meningitis, Bacterial http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25799317&form=6&db=m LTA4H genotype is associated with susceptibility to bacterial meningitis but is not a critical determinant of outcome. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,4,0 3.3.2.6 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16282974&form=6&db=m A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,2,0 3.3.2.6 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18547289&form=6&db=m The role of LTA4H and ALOX5AP polymorphism in asthma and allergy susceptibility. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2 3.3.2.6 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19578513&form=6&db=m Biomarkers and Bioassays for Cardiovascular Diseases: Present and Future. causal interaction,diagnostic usage,therapeutic application,unassigned 2,1,1,0 3.3.2.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24653816&form=6&db=m Tissue-based microarray expression of genes predictive of metastasis in uveal melanoma and differentially expressed in metastatic uveal melanoma. causal interaction,diagnostic usage,unassigned 1,3,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8615763&form=6&db=m The human leukotriene A4 hydrolase gene is expressed in two alternatively spliced mRNA forms. causal interaction,ongoing research,unassigned 1,4,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8918363&form=6&db=m Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,3 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9608670&form=6&db=m Leukotriene B4. causal interaction,unassigned 4,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12865451&form=6&db=m Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15134534&form=6&db=m Leukotriene A4 hydrolase as a target for cancer prevention and therapy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17298411&form=6&db=m Immune regulatory functions of human beta-defensin-2 in odontoblast-like cells. ongoing research,unassigned 1,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18591367&form=6&db=m Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,2,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19531649&form=6&db=m [6]-Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase. causal interaction,therapeutic application,unassigned 1,4,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20952510&form=6&db=m Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A4 hydrolase. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,4,2 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24366255&form=6&db=m Expression Analysis of Leukotriene-Inflammatory Gene Interaction Network in Patients with Coronary Artery Disease. causal interaction,diagnostic usage,unassigned 4,2,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24385243&form=6&db=m Positioning of aminopeptidase inhibitors in next generation cancer therapy. causal interaction,therapeutic application,unassigned 4,4,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25239251&form=6&db=m Gene polymorphisms in patients with pulmonary tuberculosis from Mozambique. causal interaction,ongoing research,unassigned 2,3,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28575166&form=6&db=m LTA4H regulates cell cycle and skin carcinogenesis. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,2,4 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30058075&form=6&db=m Leukotriene A4 hydrolase: an emerging target of natural products for cancer chemoprevention and chemotherapy. causal interaction,therapeutic application,unassigned 4,4,0 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31229286&form=6&db=m Potential for a localized immune response by the ruminal epithelium in nonpregnant heifers following a short-term subacute ruminal acidosis challenge. unassigned - 3.3.2.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33658385&form=6&db=m Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone. causal interaction,unassigned 4,0 3.3.2.6 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10337029&form=6&db=m Gene expression of 5-lipoxygenase and LTA4 hydrolase in renal tissue of nephrotic syndrome patients. diagnostic usage,ongoing research,unassigned 1,4,0 3.3.2.6 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14986086&form=6&db=m 5-Lipoxygenase and leukotriene A4 hydrolase expression in primary nephrotic syndrome. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 3.3.2.6 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18591367&form=6&db=m Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,2,0 3.3.2.6 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32844470&form=6&db=m Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis. causal interaction,unassigned 4,0 3.3.2.6 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20952510&form=6&db=m Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A4 hydrolase. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,4,2 3.3.2.6 Pneumonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27730172&form=6&db=m Genetic regulation of expression of leukotriene A4 hydrolase. causal interaction,therapeutic application,unassigned 4,3,0 3.3.2.6 Pneumonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29682967&form=6&db=m In Vivo Two-Photon Fluorescence Imaging of the Activity of the Inflammatory Biomarker LTA4H in a Mouse Pneumonia Model. causal interaction,diagnostic usage,therapeutic application,unassigned 1,4,4,0 3.3.2.6 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21308720&form=6&db=m Associations between arachidonic acid metabolism gene polymorphisms and prostate cancer risk. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,3,2,1 3.3.2.6 Pruritus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23902965&form=6&db=m Potential new therapeutic targets for pathological pruritus. unassigned - 3.3.2.6 Psoriasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8982402&form=6&db=m Cyclosporin A down-regulates the LTA4 hydrolase level in human keratinocyte cultures. therapeutic application,unassigned 4,0 3.3.2.6 Psoriasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9413890&form=6&db=m Significance of leukotriene-A4 hydrolase in the pathogenesis of psoriasis. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 3.3.2.6 Pulmonary Arterial Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23986401&form=6&db=m Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension. causal interaction,unassigned 4,0 3.3.2.6 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21502100&form=6&db=m Leukotriene A4 hydrolase: an anti-inflammatory role for a proinflammatory enzyme. therapeutic application,unassigned 1,0 3.3.2.6 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22206291&form=6&db=m The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers. therapeutic application,unassigned 1,0 3.3.2.6 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27232150&form=6&db=m Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation. causal interaction,therapeutic application,unassigned 3,4,0 3.3.2.6 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31751136&form=6&db=m Effect of Modifier Structure on the Activation of Leukotriene A4 Hydrolase Aminopeptidase Activity. causal interaction,unassigned 1,0 3.3.2.6 Pulmonary Emphysema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21983441&form=6&db=m Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysema. ongoing research,unassigned 1,0 3.3.2.6 Skin Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28575166&form=6&db=m LTA4H regulates cell cycle and skin carcinogenesis. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,2,4 3.3.2.6 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31287215&form=6&db=m Mass Spectrometric Analysis Identifies AIMP1 and LTA4H as FSCN1-Binding Proteins in Laryngeal Squamous Cell Carcinoma. diagnostic usage,unassigned 2,0 3.3.2.6 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18318662&form=6&db=m Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population. unassigned - 3.3.2.6 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26714527&form=6&db=m [Study on the association between leukotriene A4 hydrolase gene polymorphism and ischemic stroke]. diagnostic usage,ongoing research,unassigned 3,1,0 3.3.2.6 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20211140&form=6&db=m The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. causal interaction,therapeutic application,unassigned 4,1,0 3.3.2.6 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23874453&form=6&db=m An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. unassigned - 3.3.2.6 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25257262&form=6&db=m Relationship between human LTA4H polymorphisms and extra-pulmonary tuberculosis in an ethnic Han Chinese population in Eastern China. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 3.3.2.6 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31093505&form=6&db=m The Polymorphism rs17525495 of LTA4H Is Associated with Susceptibility of Crohn's Disease instead of Intestinal Tuberculosis in a Chinese Han Population. diagnostic usage,unassigned 3,0 3.3.2.6 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31817174&form=6&db=m Association of Leukotriene A4 Hydrolase with Tuberculosis Susceptibility Using Genomic Data in Portugal. causal interaction,unassigned 2,0 3.3.2.6 Tuberculosis, Lymph Node http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25257262&form=6&db=m Relationship between human LTA4H polymorphisms and extra-pulmonary tuberculosis in an ethnic Han Chinese population in Eastern China. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25257262&form=6&db=m Relationship between human LTA4H polymorphisms and extra-pulmonary tuberculosis in an ethnic Han Chinese population in Eastern China. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25799317&form=6&db=m LTA4H genotype is associated with susceptibility to bacterial meningitis but is not a critical determinant of outcome. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,4,0 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28419315&form=6&db=m Clinical Parameters, Routine Inflammatory Markers, and LTA4H Genotype as Predictors of Mortality Among 608 Patients With Tuberculous Meningitis in Indonesia. diagnostic usage,therapeutic application,unassigned 4,1,0 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28419367&form=6&db=m Evaluating the Impact of LTA4H Genotype and Immune Status on Survival From Tuberculous Meningitis. diagnostic usage,ongoing research,unassigned 3,2,0 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28419368&form=6&db=m Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,3,0 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30273246&form=6&db=m Tuberculosis of the Central Nervous System. causal interaction,therapeutic application,unassigned 4,1,0 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30363837&form=6&db=m Adjunctive dexamethasone for the treatment of HIV-uninfected adults with tuberculous meningitis stratified by Leukotriene A4 hydrolase genotype (LAST ACT): Study protocol for a randomised double blind placebo controlled non-inferiority trial. causal interaction,therapeutic application,unassigned 1,4,0 3.3.2.6 Tuberculosis, Meningeal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33416499&form=6&db=m A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis. diagnostic usage,unassigned 3,0 3.3.2.6 Tuberculosis, Osteoarticular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25257262&form=6&db=m Relationship between human LTA4H polymorphisms and extra-pulmonary tuberculosis in an ethnic Han Chinese population in Eastern China. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 3.3.2.6 Tuberculosis, Pleural http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25257262&form=6&db=m Relationship between human LTA4H polymorphisms and extra-pulmonary tuberculosis in an ethnic Han Chinese population in Eastern China. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 3.3.2.6 Tuberculosis, Pulmonary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21112816&form=6&db=m Association analysis of the LTA4H gene polymorphisms and pulmonary tuberculosis in 9115 subjects. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,4,2 3.3.2.6 Tuberculosis, Pulmonary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25239251&form=6&db=m Gene polymorphisms in patients with pulmonary tuberculosis from Mozambique. causal interaction,ongoing research,unassigned 2,3,0 3.3.2.6 Tuberculosis, Pulmonary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25257262&form=6&db=m Relationship between human LTA4H polymorphisms and extra-pulmonary tuberculosis in an ethnic Han Chinese population in Eastern China. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1