3.1.1.79 Arthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19239908&form=6&db=m Cyclooxygenase-2 inhibition reverts the decrease in adiponectin levels and attenuates the loss of white adipose tissue during chronic inflammation. diagnostic usage,ongoing research,unassigned 3,3,0 3.1.1.79 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10064727&form=6&db=m Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages. ongoing research,unassigned 2,0 3.1.1.79 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12036961&form=6&db=m Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase. ongoing research,therapeutic application,unassigned 4,1,0 3.1.1.79 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14643795&form=6&db=m Reduced atherosclerosis in hormone-sensitive lipase transgenic mice overexpressing cholesterol acceptors. ongoing research,unassigned 1,0 3.1.1.79 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21111707&form=6&db=m Abrogation of neutral cholesterol ester hydrolytic activity causes adrenal enlargement. unassigned - 3.1.1.79 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29906613&form=6&db=m Fatty acid-binding protein 5 (FABP5) promotes lipolysis of lipid droplets, de novo fatty acid (FA) synthesis and activation of nuclear factor-kappa B (NF-?B) signaling in cancer cells. causal interaction,ongoing research,unassigned 3,1,0 3.1.1.79 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10393105&form=6&db=m Metabolic characteristics of a human hepatoma cell line stably transfected with hormone-sensitive lipase. ongoing research,unassigned 4,0 3.1.1.79 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14745166&form=6&db=m Comparison of the changes in lipid metabolism between hepatoma-bearing and lipopolysaccharide-treated rats. diagnostic usage,unassigned 1,0 3.1.1.79 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20628900&form=6&db=m Effects of sulfur amino acids, L: -methionine, L: -cystine and L: -cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes. ongoing research,unassigned 3,0 3.1.1.79 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28515323&form=6&db=m ?-Adrenergic induction of lipolysis in hepatocytes is inhibited by ethanol exposure. diagnostic usage,ongoing research,unassigned 3,1,0 3.1.1.79 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25300978&form=6&db=m Inborn errors of cytoplasmic triglyceride metabolism. unassigned - 3.1.1.79 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26663986&form=6&db=m Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans. diagnostic usage,unassigned 1,0 3.1.1.79 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7695773&form=6&db=m Expression of hormone-sensitive lipase in the human colon adenocarcinoma cell line HT29. causal interaction,ongoing research,unassigned 1,4,0 3.1.1.79 Dandruff http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27130210&form=6&db=m Secreted lipases from Malassezia globosa: recombinant expression and determination of their substrate specificities. unassigned - 3.1.1.79 Dermatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27130210&form=6&db=m Secreted lipases from Malassezia globosa: recombinant expression and determination of their substrate specificities. unassigned - 3.1.1.79 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9867220&form=6&db=m The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity. ongoing research,unassigned 4,0 3.1.1.79 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12139017&form=6&db=m Cyclipostins, novel hormone-sensitive lipase inhibitors from Streptomyces sp. DSM 13381. II. Isolation, structure elucidation and biological properties. causal interaction,therapeutic application,unassigned 3,2,0 3.1.1.79 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15609025&form=6&db=m Hormone-sensitive lipase is reduced in the adipose tissue of patients with type 2 diabetes mellitus: influence of IL-6 infusion. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,4,0 3.1.1.79 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30773997&form=6&db=m Bioactive compounds in plant materials for the prevention of diabetesand obesity. unassigned - 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9519728&form=6&db=m Human hormone-sensitive lipase: genetic mapping, identification of a new dinucleotide repeat, and association with obesity and NIDDM. causal interaction,ongoing research,unassigned 2,2,0 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11718066&form=6&db=m [Multivariate logistic regression analysis on the risk factors of type 2 diabetes mellitus] diagnostic usage,ongoing research,unassigned 3,3,0 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12711310&form=6&db=m Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding. causal interaction,unassigned 3,0 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14711311&form=6&db=m Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. causal interaction,therapeutic application,unassigned 1,4,0 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15609025&form=6&db=m Hormone-sensitive lipase is reduced in the adipose tissue of patients with type 2 diabetes mellitus: influence of IL-6 infusion. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,4,0 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16162821&form=6&db=m Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose. unassigned - 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17765364&form=6&db=m Effects of monounsaturated vs. saturated fat on postprandial lipemia and adipose tissue lipases in type 2 diabetes. ongoing research,unassigned 4,0 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24848981&form=6&db=m Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes. causal interaction,unassigned 3,0 3.1.1.79 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30773997&form=6&db=m Bioactive compounds in plant materials for the prevention of diabetesand obesity. unassigned - 3.1.1.79 Diabetic Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18413675&form=6&db=m Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice. causal interaction,therapeutic application,unassigned 3,3,0 3.1.1.79 Dyslipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30695359&form=6&db=m [Diagnosis of Secondary Hyperlipidemia due to Diabetes]. causal interaction,unassigned 4,0 3.1.1.79 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12638006&form=6&db=m Fold prediction and comparative modeling of Bdm1: a probable alpha/beta hydrolase associated with hot water epilepsy. therapeutic application,unassigned 1,0 3.1.1.79 Fatty Liver http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23688034&form=6&db=m Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver. causal interaction,therapeutic application,unassigned 1,1,0 3.1.1.79 Fatty Liver http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29232702&form=6&db=m Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice. causal interaction,ongoing research,unassigned 4,1,0 3.1.1.79 Fatty Liver http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33692445&form=6&db=m Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,2,0 3.1.1.79 Glucose Intolerance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1542265&form=6&db=m Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,3,2 3.1.1.79 Glucose Intolerance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14711311&form=6&db=m Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. causal interaction,therapeutic application,unassigned 1,4,0 3.1.1.79 HIV-Associated Lipodystrophy Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19707470&form=6&db=m Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome. ongoing research,unassigned 1,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11316346&form=6&db=m The adipose tissue phenotype of hormone-sensitive lipase deficiency in mice. causal interaction,ongoing research,unassigned 4,4,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11564684&form=6&db=m Infertility and testicular defects in hormone-sensitive lipase-deficient mice. causal interaction,therapeutic application,unassigned 4,1,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11717312&form=6&db=m Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. causal interaction,ongoing research,unassigned 4,2,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11809748&form=6&db=m Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle. causal interaction,ongoing research,unassigned 3,2,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12193545&form=6&db=m Hormone-sensitive lipase deficiency in mice causes lipid storage in the adrenal cortex and impaired corticosterone response to corticotropin stimulation. causal interaction,ongoing research,unassigned 3,2,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12840660&form=6&db=m Letting lipids go: hormone-sensitive lipase. causal interaction,therapeutic application,unassigned 4,3,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15142983&form=6&db=m Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact. ongoing research,unassigned 2,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19619509&form=6&db=m Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice. causal interaction,ongoing research,unassigned 4,4,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23369366&form=6&db=m Hormone-sensitive lipase deficiency disturbs the fatty acid composition of mouse testis. unassigned - 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25100058&form=6&db=m Hormone-sensitive lipase deficiency in humans. causal interaction,unassigned 4,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27355565&form=6&db=m Hormone-sensitive lipase deficiency disturbs lipid composition of plasma membrane microdomains from mouse testis. ongoing research,unassigned 2,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27920259&form=6&db=m Hormone-sensitive lipase deficiency alters gene expression and cholesterol content of mouse testis. causal interaction,ongoing research,unassigned 3,2,0 3.1.1.79 hormone-sensitive lipase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34461308&form=6&db=m Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis. causal interaction,therapeutic application,unassigned 4,1,0 3.1.1.79 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26111885&form=6&db=m FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity. causal interaction,unassigned 1,0 3.1.1.79 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8397127&form=6&db=m Chronic exposure of rat fat cells to insulin enhances lipolysis and activation of partially purified hormone-sensitive lipase. causal interaction,unassigned 3,0 3.1.1.79 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15522994&form=6&db=m Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. causal interaction,unassigned 4,0 3.1.1.79 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16421341&form=6&db=m Muscle type-dependent responses to insulin in intramyocellular triglyceride turnover in obese rats. causal interaction,diagnostic usage,therapeutic application,unassigned 4,2,3,0 3.1.1.79 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26111885&form=6&db=m FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity. causal interaction,unassigned 1,0 3.1.1.79 Hyperlipidemia, Familial Combined http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9351402&form=6&db=m Adipose tissue lipoprotein lipase and hormone-sensitive lipase. Contrasting findings in familial combined hyperlipidemia and insulin resistance syndrome. ongoing research,therapeutic application,unassigned 2,1,0 3.1.1.79 Hyperlipidemia, Familial Combined http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11932285&form=6&db=m In vivo modulation of plasma free fatty acids in patients with familial combined hyperlipidemia using lipid-lowering medication. therapeutic application,unassigned 1,0 3.1.1.79 Hyperlipidemia, Familial Combined http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11979403&form=6&db=m C3, hormone-sensitive lipase, and peroxisome proliferator-activated receptor gamma expression in adipose tissue of familial combined hyperlipidemia patients. causal interaction,ongoing research,unassigned 3,4,0 3.1.1.79 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9351402&form=6&db=m Adipose tissue lipoprotein lipase and hormone-sensitive lipase. Contrasting findings in familial combined hyperlipidemia and insulin resistance syndrome. ongoing research,therapeutic application,unassigned 2,1,0 3.1.1.79 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11932285&form=6&db=m In vivo modulation of plasma free fatty acids in patients with familial combined hyperlipidemia using lipid-lowering medication. therapeutic application,unassigned 1,0 3.1.1.79 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11979403&form=6&db=m C3, hormone-sensitive lipase, and peroxisome proliferator-activated receptor gamma expression in adipose tissue of familial combined hyperlipidemia patients. causal interaction,ongoing research,unassigned 3,4,0 3.1.1.79 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17765364&form=6&db=m Effects of monounsaturated vs. saturated fat on postprandial lipemia and adipose tissue lipases in type 2 diabetes. ongoing research,unassigned 4,0 3.1.1.79 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20628900&form=6&db=m Effects of sulfur amino acids, L: -methionine, L: -cystine and L: -cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes. ongoing research,unassigned 3,0 3.1.1.79 Hyperlipidemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26111885&form=6&db=m FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity. causal interaction,unassigned 1,0 3.1.1.79 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2459&form=6&db=m Adrenergic binding sites and enzyme activities in the heart of hyperthyroid rats. causal interaction,diagnostic usage,unassigned 4,3,0 3.1.1.79 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8989252&form=6&db=m Catecholamine-induced adipocyte lipolysis in human hyperthyroidism. diagnostic usage,unassigned 3,0 3.1.1.79 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17389707&form=6&db=m The atrial natriuretic peptide- and catecholamine-induced lipolysis and expression of related genes in adipose tissue in hypothyroid and hyperthyroid patients. causal interaction,ongoing research,therapeutic application,unassigned 3,2,4,0 3.1.1.79 Hypertriglyceridemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25300978&form=6&db=m Inborn errors of cytoplasmic triglyceride metabolism. unassigned - 3.1.1.79 Hypothyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8157718&form=6&db=m Adrenergic regulation of lipolysis in fat cells from hyperthyroid and hypothyroid patients. causal interaction,therapeutic application,unassigned 1,1,0 3.1.1.79 Ichthyosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25300978&form=6&db=m Inborn errors of cytoplasmic triglyceride metabolism. unassigned - 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12101309&form=6&db=m Legionella pneumophila genes that encode lipase and phospholipase C activities. causal interaction,therapeutic application,unassigned 1,1,0 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15842622&form=6&db=m A secreted lipase of Fusarium graminearum is a virulence factor required for infection of cereals. causal interaction,unassigned 2,0 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16126835&form=6&db=m Secretome analysis reveals an Arabidopsis lipase involved in defense against Alternaria brassicicola. diagnostic usage,unassigned 1,0 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17555271&form=6&db=m RAS2 regulates growth and pathogenesis in Fusarium graminearum. therapeutic application,unassigned 1,0 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21565242&form=6&db=m Overexpression of Rv3097c in Mycobacterium bovis BCG abolished the efficacy of BCG vaccine to protect against Mycobacterium tuberculosis infection in mice. ongoing research,therapeutic application,unassigned 1,2,0 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23236531&form=6&db=m Clofazimine modulates the expression of lipid metabolism proteins in Mycobacterium leprae-infected macrophages. unassigned - 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24781155&form=6&db=m Resistance of callose synthase activity to free fatty acid inhibition as an indicator of Fusarium head blight resistance in wheat. causal interaction,therapeutic application,unassigned 2,1,0 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25763484&form=6&db=m Resistance of callose synthase activity to free fatty acid inhibition as an indicator of Fusarium head blight resistance in wheat. causal interaction,therapeutic application,unassigned 2,1,0 3.1.1.79 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=100546381&form=6&db=m The secreted lipase FGL1 is sufficient to restore the initial infection step to the apathogenic Fusarium graminearum MAP kinase disruption mutant ?gpmk1 unassigned - 3.1.1.79 Infertility http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30937958&form=6&db=m The N-terminal His-tag affects the triglyceride lipase activity of hormone-sensitive lipase in testis. ongoing research,unassigned 2,0 3.1.1.79 Infertility, Male http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10639158&form=6&db=m Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity. causal interaction,unassigned 4,0 3.1.1.79 Infertility, Male http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15292223&form=6&db=m The testicular form of hormone-sensitive lipase HSLtes confers rescue of male infertility in HSL-deficient mice. ongoing research,unassigned 3,0 3.1.1.79 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2205696&form=6&db=m Hepatic steatosis during convalescence from influenza B infection in ferrets with postprandial hyperinsulinemia. unassigned - 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9100587&form=6&db=m Impaired adipocyte lipolysis in nonobese women with the polycystic ovary syndrome: a possible link to insulin resistance? causal interaction,therapeutic application,unassigned 4,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9351402&form=6&db=m Adipose tissue lipoprotein lipase and hormone-sensitive lipase. Contrasting findings in familial combined hyperlipidemia and insulin resistance syndrome. ongoing research,therapeutic application,unassigned 2,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11714847&form=6&db=m Two novel prevalent polymorphisms in the hormone-sensitive lipase gene have no effect on insulin sensitivity of lipolysis and glucose disposal. ongoing research,therapeutic application,unassigned 3,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11932285&form=6&db=m In vivo modulation of plasma free fatty acids in patients with familial combined hyperlipidemia using lipid-lowering medication. therapeutic application,unassigned 1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12835327&form=6&db=m Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact. ongoing research,unassigned 4,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15026062&form=6&db=m Carbazates as potent inhibitors of hormone-sensitive lipase. causal interaction,therapeutic application,unassigned 4,3,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15701680&form=6&db=m Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart. ongoing research,therapeutic application,unassigned 4,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16162821&form=6&db=m Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose. unassigned - 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16269451&form=6&db=m Peroxisome proliferator-activated receptor-gamma transcriptionally up-regulates hormone-sensitive lipase via the involvement of specificity protein-1. unassigned - 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16362285&form=6&db=m The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,2,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16456093&form=6&db=m Peroxisome proliferator-activated receptor-alpha,gamma-agonist improves insulin sensitivity and prevents loss of left ventricular function in obese dyslipidemic mice. causal interaction,unassigned 1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17318625&form=6&db=m Atrial natriuretic peptide inhibits the production of adipokines and cytokines linked to inflammation and insulin resistance in human subcutaneous adipose tissue. ongoing research,unassigned 1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17356053&form=6&db=m Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. diagnostic usage,ongoing research,unassigned 1,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19785415&form=6&db=m Omics Analyses Reveal a Potential Link between Hormone-Sensitive Lipase and Polyamine Metabolism. unassigned - 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21291723&form=6&db=m Male hypogonadism: The unrecognized cardiovascular risk factor. causal interaction,unassigned 4,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22551950&form=6&db=m Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome. therapeutic application,unassigned 1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23471217&form=6&db=m High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle. causal interaction,diagnostic usage,therapeutic application,unassigned 1,3,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23688034&form=6&db=m Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver. causal interaction,therapeutic application,unassigned 1,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25904554&form=6&db=m Antiobesity Effect of a Small Molecule Repressor of ROR?. causal interaction,therapeutic application,unassigned 1,4,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26111885&form=6&db=m FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity. causal interaction,unassigned 1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30695359&form=6&db=m [Diagnosis of Secondary Hyperlipidemia due to Diabetes]. causal interaction,unassigned 4,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32255390&form=6&db=m The 1975 type Japanese diet improves the gut microbial flora and inhibits visceral fat accumulation in mice. ongoing research,therapeutic application,unassigned 2,1,0 3.1.1.79 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32694809&form=6&db=m Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity. causal interaction,ongoing research,unassigned 3,3,0 3.1.1.79 Ketosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22296673&form=6&db=m Concentrations of Plasma Metabolites, Hormones, and mRNA Abundance of Adipose Leptin and Hormone-Sensitive Lipase in Ketotic and Nonketotic Dairy Cows. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,3,0 3.1.1.79 Lipidoses http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10668812&form=6&db=m Metabolic and hormonal alterations in cats with hepatic lipidosis. causal interaction,unassigned 3,0 3.1.1.79 Lipodystrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33692445&form=6&db=m Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,2,0 3.1.1.79 Lipoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1261213&form=6&db=m Lipoprotein lipase and hormone-sensitive lipase activities in human subcutaneous lipomas: comparison with normal subcutaneous adipose tissue. diagnostic usage,ongoing research,unassigned 4,4,0 3.1.1.79 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30580553&form=6&db=m n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. ongoing research,unassigned 1,0 3.1.1.79 Liver Diseases, Alcoholic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30580553&form=6&db=m n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. ongoing research,unassigned 1,0 3.1.1.79 Lymphoma, B-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26829127&form=6&db=m Trace Mineral Overload Induced Hepatic Oxidative Damage and Apoptosis in Pigs with Long-Term High-Level Dietary Mineral Exposure. unassigned - 3.1.1.79 Marek Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15890938&form=6&db=m vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus. causal interaction,unassigned 1,0 3.1.1.79 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10889791&form=6&db=m Genetics of the metabolic syndrome. unassigned - 3.1.1.79 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14711311&form=6&db=m Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. causal interaction,therapeutic application,unassigned 1,4,0 3.1.1.79 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22551950&form=6&db=m Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome. therapeutic application,unassigned 1,0 3.1.1.79 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26996629&form=6&db=m Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. ongoing research,unassigned 4,0 3.1.1.79 Muscular Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30239846&form=6&db=m The alleviative effects and related mechanisms of taurine supplementation on growth performance and carcass characteristics in broilers exposed to chronic heat stress. causal interaction,diagnostic usage,therapeutic application,unassigned 1,3,1,0 3.1.1.79 Muscular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25300978&form=6&db=m Inborn errors of cytoplasmic triglyceride metabolism. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8194485&form=6&db=m Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase. diagnostic usage,unassigned 1,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8422428&form=6&db=m Increased expression of the mRNA for hormone-sensitive lipase in adipose tissue of cancer patients. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8557225&form=6&db=m Aberrations in normal systemic lipid metabolism in ovarian cancer patients. causal interaction,diagnostic usage,unassigned 1,2,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9726225&form=6&db=m Depot-related gene expression in human subcutaneous and omental adipocytes. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10334320&form=6&db=m A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q. causal interaction,unassigned 1,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10880355&form=6&db=m The human breast carcinoma cell line HBL-100 acquires exogenous cholesterol from high-density lipoprotein via CLA-1 (CD-36 and LIMPII analogous 1)-mediated selective cholesteryl ester uptake. therapeutic application,unassigned 1,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10889786&form=6&db=m Obesity--a genetic disease of adipose tissue? causal interaction,unassigned 2,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14745722&form=6&db=m Normal and pathological human testes express hormone-sensitive lipase and the lipid receptors CLA-1/SR-BI and CD36. diagnostic usage,ongoing research,unassigned 3,4,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15168125&form=6&db=m Cancer cachexia. causal interaction,diagnostic usage,unassigned 4,2,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16219442&form=6&db=m Activity and tissue-specific expression of lipases and tumor-necrosis factor alpha in lean and obese cats. diagnostic usage,ongoing research,unassigned 3,2,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17563763&form=6&db=m Obesity and polymorphisms in genes regulating human adipose tissue. causal interaction,therapeutic application,unassigned 3,1,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18360779&form=6&db=m An unannotated alpha/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18372237&form=6&db=m Adipose tissue loss in adjuvant arthritis is associated with a decrease in lipogenesis, but not with an increase in lipolysis. diagnostic usage,unassigned 3,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18467379&form=6&db=m Effect of dermcidin, an antimicrobial peptide, on body fat mobilization in normal mice. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18685378&form=6&db=m Mechanisms to explain wasting of muscle and fat in cancer cachexia. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19239908&form=6&db=m Cyclooxygenase-2 inhibition reverts the decrease in adiponectin levels and attenuates the loss of white adipose tissue during chronic inflammation. diagnostic usage,ongoing research,unassigned 3,3,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19427183&form=6&db=m Phosphorylated glucosamine inhibits adipogenesis in 3T3-L1 adipocytes. diagnostic usage,ongoing research,unassigned 1,3,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19680725&form=6&db=m 1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydroxyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin Inhibits Adipocyte Differentiation of 3T3-L1 Fibroblasts. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19793082&form=6&db=m High expression of the evolutionarily conserved alpha/beta hydrolase domain containing 6 (ABHD6) in Ewing tumors. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20426789&form=6&db=m Role of beta1-adrenoceptor in increased lipolysis in cancer cachexia. causal interaction,unassigned 3,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21969372&form=6&db=m Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-? (TNF-?)-induced lipolysis in adipocytes. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24737494&form=6&db=m Regulation of adipocytes lipolysis by n-3 HUFA in grass carp (Ctenopharyngodon idellus) in vitro and in vivo. causal interaction,unassigned 3,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26443339&form=6&db=m Wheat gluten intake increases weight gain and adiposity associated with reduced thermogenesis and energy expenditure in an animal model of obesity. causal interaction,unassigned 1,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28124996&form=6&db=m Expression of Lipid Metabolism-Related Proteins Differs between Invasive Lobular Carcinoma and Invasive Ductal Carcinoma. diagnostic usage,ongoing research,unassigned 3,2,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28830524&form=6&db=m Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer. diagnostic usage,ongoing research,unassigned 1,3,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30580553&form=6&db=m n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. ongoing research,unassigned 1,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30773997&form=6&db=m Bioactive compounds in plant materials for the prevention of diabetesand obesity. unassigned - 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31845180&form=6&db=m Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes. ongoing research,unassigned 1,0 3.1.1.79 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33188080&form=6&db=m Fats and Mets, KRAS-Driven Lipid Dysregulation Affects Metastatic Potential in Pancreatic Cancer. causal interaction,ongoing research,unassigned 2,1,0 3.1.1.79 Non-alcoholic Fatty Liver Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30580553&form=6&db=m n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. ongoing research,unassigned 1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7489032&form=6&db=m The hormone-sensitive lipase (LIPE) gene located on chromosome 19q13.1-->13.2 is not duplicated on 19p13.3. causal interaction,unassigned 3,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8858214&form=6&db=m Adipocyte lipolysis in normal weight subjects with obesity among first-degree relatives. causal interaction,unassigned 4,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9519728&form=6&db=m Human hormone-sensitive lipase: genetic mapping, identification of a new dinucleotide repeat, and association with obesity and NIDDM. causal interaction,ongoing research,unassigned 2,2,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10409579&form=6&db=m Effect of diet on fat cell size and hormone-sensitive lipase activity. diagnostic usage,ongoing research,unassigned 2,4,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10553009&form=6&db=m Decreased expression and function of adipocyte hormone-sensitive lipase in subcutaneous fat cells of obese subjects. causal interaction,ongoing research,unassigned 4,1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10639158&form=6&db=m Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity. causal interaction,unassigned 4,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10946012&form=6&db=m Expression of nitric oxide synthases in subcutaneous adipose tissue of nonobese and obese humans. causal interaction,therapeutic application,unassigned 3,1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11246809&form=6&db=m Millennium fat-cell lipolysis reveals unsuspected novel tracks. unassigned - 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11574428&form=6&db=m A common hormone-sensitive lipase i6 gene polymorphism is associated with decreased human adipocyte lipolytic function. causal interaction,unassigned 3,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11730161&form=6&db=m Genetic variance and lipolysis regulation: implications for obesity. ongoing research,unassigned 3,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12840660&form=6&db=m Letting lipids go: hormone-sensitive lipase. causal interaction,therapeutic application,unassigned 4,3,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12954598&form=6&db=m Resistance to high-fat diet-induced obesity and altered expression of adipose-specific genes in HSL-deficient mice. diagnostic usage,ongoing research,unassigned 4,4,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13680127&form=6&db=m Fatty acid metabolism and insulin secretion in pancreatic beta cells. unassigned - 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14559324&form=6&db=m Inhibitory effects of grape seed extract on lipases. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,2,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14752112&form=6&db=m Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice. ongoing research,unassigned 2,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15498253&form=6&db=m [Expression of hormone-sensitive lipase mRNA in diet-induced obesity resistant rats] ongoing research,unassigned 2,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15701680&form=6&db=m Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart. ongoing research,therapeutic application,unassigned 4,1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15826474&form=6&db=m Adiponectin expression and adipose tissue lipolytic activity in lean and obese women. causal interaction,unassigned 2,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15961788&form=6&db=m Human hormone-sensitive lipase (HSL): expression in white fat corrects the white adipose phenotype of HSL-deficient mice. causal interaction,unassigned 2,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16938460&form=6&db=m Importance of TNFalpha and neutral lipases in human adipose tissue lipolysis. causal interaction,therapeutic application,unassigned 3,1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17327373&form=6&db=m Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis. unassigned - 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18398140&form=6&db=m Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation. causal interaction,diagnostic usage,therapeutic application,unassigned 3,2,1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19823091&form=6&db=m Zinc-alpha2-glycoprotein in cachexia and obesity. causal interaction,unassigned 3,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20017959&form=6&db=m Depot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obese. causal interaction,unassigned 1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20641056&form=6&db=m Effect of pu-erh tea on body fat and lipid profiles in rats with diet-induced obesity. causal interaction,diagnostic usage,unassigned 2,3,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20843949&form=6&db=m Skeletal Muscle Lipase Content and Activity in Obesity and Type 2 Diabetes. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22972182&form=6&db=m Effect of Physical Training on the Adipose Tissue of Diet-induced Obesity Mice: Interaction Between Reactive Oxygen Species and Lipolysis. causal interaction,unassigned 4,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23688034&form=6&db=m Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver. causal interaction,therapeutic application,unassigned 1,1,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25904554&form=6&db=m Antiobesity Effect of a Small Molecule Repressor of ROR?. causal interaction,therapeutic application,unassigned 1,4,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26996629&form=6&db=m Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. ongoing research,unassigned 4,0 3.1.1.79 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30463291&form=6&db=m Ishige okamurae Extract Suppresses Obesity and Hepatic Steatosis in High Fat Diet-Induced Obese Mice. causal interaction,unassigned 1,0 3.1.1.79 Obesity, Abdominal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9867220&form=6&db=m The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity. ongoing research,unassigned 4,0 3.1.1.79 Overweight http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18249203&form=6&db=m Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene. unassigned - 3.1.1.79 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30086728&form=6&db=m Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice. causal interaction,unassigned 4,0 3.1.1.79 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33188080&form=6&db=m Fats and Mets, KRAS-Driven Lipid Dysregulation Affects Metastatic Potential in Pancreatic Cancer. causal interaction,ongoing research,unassigned 2,1,0 3.1.1.79 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9784238&form=6&db=m Phenytoin alters transcript levels of hormone-sensitive lipase in muscle from horses with hyperkalemic periodic paralysis. ongoing research,unassigned 1,0 3.1.1.79 Paralysis, Hyperkalemic Periodic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9784238&form=6&db=m Phenytoin alters transcript levels of hormone-sensitive lipase in muscle from horses with hyperkalemic periodic paralysis. ongoing research,unassigned 1,0 3.1.1.79 Polycystic Ovary Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19423542&form=6&db=m Omental adipose tissue overexpression of fatty acid transporter CD36 and decreased expression of hormone-sensitive lipase in insulin-resistant women with polycystic ovary syndrome. causal interaction,ongoing research,unassigned 2,1,0 3.1.1.79 Pulmonary Emphysema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19250629&form=6&db=m Age-related pulmonary emphysema in mice lacking alpha/beta hydrolase domain containing 2 gene. ongoing research,therapeutic application,unassigned 4,1,0 3.1.1.79 Sarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19793082&form=6&db=m High expression of the evolutionarily conserved alpha/beta hydrolase domain containing 6 (ABHD6) in Ewing tumors. unassigned - 3.1.1.79 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=179104&form=6&db=m Mechanism of actions of adrenaline and ACTH in fat mobilization. unassigned - 3.1.1.79 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6271720&form=6&db=m Effect of nutritional status on swine adipose tissue lipolytic activities. diagnostic usage,ongoing research,unassigned 2,2,0 3.1.1.79 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16354661&form=6&db=m A Novel Lipase Belonging to the Hormone-sensitive Lipase Family Induced under Starvation to Utilize Stored Triacylglycerol in Mycobacterium tuberculosis. unassigned - 3.1.1.79 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20706869&form=6&db=m Effect of starvation on activities and mRNA expression of lipoprotein lipase and hormone-sensitive lipase in tilapia (Oreochromis niloticus x O. areus). diagnostic usage,ongoing research,unassigned 3,3,0 3.1.1.79 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16325466&form=6&db=m Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases. ongoing research,unassigned 4,0 3.1.1.79 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16354661&form=6&db=m A Novel Lipase Belonging to the Hormone-sensitive Lipase Family Induced under Starvation to Utilize Stored Triacylglycerol in Mycobacterium tuberculosis. unassigned - 3.1.1.79 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21565242&form=6&db=m Overexpression of Rv3097c in Mycobacterium bovis BCG abolished the efficacy of BCG vaccine to protect against Mycobacterium tuberculosis infection in mice. ongoing research,therapeutic application,unassigned 1,2,0 3.1.1.79 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23029536&form=6&db=m MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth. ongoing research,unassigned 2,0