2.3.1.241	Arthritis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21088052&form=6&db=m	Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production.	causal interaction,therapeutic application,unassigned	1,1,0	
2.3.1.241	Exanthema	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19390612&form=6&db=m	Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy.	causal interaction,diagnostic usage,ongoing research,therapeutic application	3,1,3,1	
2.3.1.241	Hepatitis B	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18982519&form=6&db=m	Enhancement of T-helper type I immune responses against hepatitis B surface antigen by LPS derivatives adjuvanted liposomes delivery system.	diagnostic usage,ongoing research,unassigned	3,2,0	
2.3.1.241	Infections	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20439476&form=6&db=m	The structure of Neisseria meningitidis lipid A determines outcome in experimental meningococcal disease.	ongoing research,therapeutic application,unassigned	2,2,0	
2.3.1.241	Influenza, Human	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19059296&form=6&db=m	Incorporation of LpxL1, a detoxified lipopolysaccharide adjuvant, in influenza H5N1 virosomes increases vaccine immunogenicity.	causal interaction,diagnostic usage,ongoing research,therapeutic application	1,3,2,3	
2.3.1.241	Meningitis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22261040&form=6&db=m	Invasive meningococcal capsular group y disease, England and Wales, 2007-2009.	causal interaction,diagnostic usage,unassigned	1,2,0	
2.3.1.241	Meningitis, Meningococcal	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19390612&form=6&db=m	Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy.	causal interaction,diagnostic usage,ongoing research,therapeutic application	3,1,3,1	
2.3.1.241	Meningococcal Infections	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28024455&form=6&db=m	The Neisseria meningitidis lpxL1 mutant induces less tissue factor expression and activity in primary human monocytes and monocyte-derived microvesicles than the wild type meningococcus.	ongoing research,unassigned	1,0	
2.3.1.241	Meningococcal Infections	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29313733&form=6&db=m	Whole-blood incubation with the Neisseria meningitidis lpxL1 mutant induces less pro-inflammatory cytokines than the wild type, and IL-10 reduces the MyD88-dependent cytokines.	therapeutic application,unassigned	1,0	
2.3.1.241	Neoplasms	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11553534&form=6&db=m	Modification of lipid A biosynthesis in Neisseria meningitidis lpxL mutants: influence on lipopolysaccharide structure, toxicity, and adjuvant activity.	diagnostic usage,therapeutic application,unassigned	1,2,0	
2.3.1.241	Neoplasms	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15972495&form=6&db=m	Characterization of native outer membrane vesicles from lpxL mutant strains of Neisseria meningitidis for use in parenteral vaccination.	unassigned	-	
2.3.1.241	Pneumonia	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22261040&form=6&db=m	Invasive meningococcal capsular group y disease, England and Wales, 2007-2009.	causal interaction,diagnostic usage,unassigned	1,2,0	
2.3.1.241	Tetanus	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24351756&form=6&db=m	Neisseria meningitidis native outer membrane vesicles containing different lipopolysaccharide glycoforms as adjuvants for meningococcal and nonmeningococcal antigens.	ongoing research,therapeutic application,unassigned	2,1,0	
2.3.1.241	Whooping Cough	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17967899&form=6&db=m	A novel secondary acyl chain in the lipopolysaccharide of Bordetella pertussis required for efficient infection of human macrophages.	causal interaction,unassigned	1,0