1.2.1.59 6-phosphofructokinase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6449564&form=6&db=m Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease). causal interaction,ongoing research,unassigned 4,1,0 1.2.1.59 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=954168&form=6&db=m Effects of treatment with pyruvate and tromethamine in experimental myocardial ischemia. unassigned - 1.2.1.59 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8620602&form=6&db=m Binding of cytosolic proteins to myofibrils in ischemic rat hearts. unassigned - 1.2.1.59 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10915225&form=6&db=m Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones. ongoing research,unassigned 2,0 1.2.1.59 Acidosis, Lactic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19571378&form=6&db=m Regulation of glyceraldehyde 3-phosphate dehydrogenase expression by metformin in HepG2 cells. causal interaction,unassigned 3,0 1.2.1.59 Acquired Immunodeficiency Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15191658&form=6&db=m [Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference] causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Acquired Immunodeficiency Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32079455&form=6&db=m Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block. ongoing research,unassigned 2,0 1.2.1.59 ACTH-Secreting Pituitary Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10768834&form=6&db=m Decreased expression of corticotropin-releasing factor-binding protein mRNA in ACTH-secreting pituitary adenomas. ongoing research,unassigned 2,0 1.2.1.59 ACTH-Secreting Pituitary Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10902805&form=6&db=m Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion. unassigned - 1.2.1.59 Acute Kidney Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19923797&form=6&db=m The modifier protein of glyceraldehyde-3-phosphate dehydrogenase reduces free radical-mediated renal damage in a rat model of acute kidney injury. ongoing research,unassigned 4,0 1.2.1.59 Acute Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24902773&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice. causal interaction,therapeutic application,unassigned 2,3,0 1.2.1.59 Acute Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28753256&form=6&db=m A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation. causal interaction,ongoing research,therapeutic application,unassigned 3,3,2,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2765128&form=6&db=m Increased expression of glycolysis-associated genes in oncogene-transformed and growth-accelerated states. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2879649&form=6&db=m Sequential histochemical and morphometric studies on preneoplastic and neoplastic lesions induced in rat colon by 1,2-dimethylhydrazine. unassigned - 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3180054&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8481901&form=6&db=m Association of glyceraldehyde-3-phosphate dehydrogenase expression with cell motility and metastatic potential of rat prostatic adenocarcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17884296&form=6&db=m Inactivation of metabolic enzymes by photo-treatment with zinc meta N-methylpyridylporphyrin. therapeutic application,unassigned 1,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20193080&form=6&db=m Simultaneous down-regulation of tumor suppressor genes RBSP3/CTDSPL, NPRL2/G21 and RASSF1A in primary non-small cell lung cancer. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20872808&form=6&db=m CD133 mRNA expression and microsatellite instability in colorectal carcinoma. diagnostic usage,ongoing research,unassigned 4,1,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23124112&form=6&db=m UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells. unassigned - 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25625240&form=6&db=m Colon cancer stem cell markers CD44 and CD133 in patients with colorectal cancer and synchronous hepatic metastases. diagnostic usage,unassigned 4,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28962872&form=6&db=m UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism. causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30581507&form=6&db=m Correlation study of GAPDH, Bcl-2, and Bax protein immunoexpression in patients with colorectal adenocarcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,3 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14963017&form=6&db=m The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis. causal interaction,unassigned 4,0 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17540040&form=6&db=m Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18927512&form=6&db=m The cytotoxic ribonuclease onconase targets RNA interference (siRNA). ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19144146&form=6&db=m Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,4 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25844669&form=6&db=m Inferring genome-wide functional modulatory network: a case study on NF-?B/RelA transcription factor. causal interaction,unassigned 1,0 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31421831&form=6&db=m Guanylate binding protein 1 (GBP-1) promotes cell motility and invasiveness of lung adenocarcinoma. causal interaction,unassigned 4,0 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31774373&form=6&db=m LncRNA MALAT1 regulates trophoblast cells migration and invasion via miR-206/IGF-1 axis. diagnostic usage,unassigned 3,0 1.2.1.59 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33029490&form=6&db=m Aberrant Methylation and Differential Expression of SLC2A1, TNS4, GAPDH, ATP8A2, and CASZ1 Are Associated with the Prognosis of Lung Adenocarcinoma. causal interaction,diagnostic usage,unassigned 3,2,0 1.2.1.59 Adenolymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32365590&form=6&db=m Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,3,1 1.2.1.59 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1848480&form=6&db=m Histochemical profile of mouse hepatocellular adenomas and carcinomas induced by a single dose of diethylnitrosamine. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10328219&form=6&db=m Rapid screening of specific changes in mRNA in thyroid carcinomas by sequence specific-differential display: decreased expression of acid ceramidase mRNA in malignant and benign thyroid tumors. causal interaction,diagnostic usage,unassigned 4,4,0 1.2.1.59 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11231991&form=6&db=m Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas. causal interaction,diagnostic usage,unassigned 4,1,0 1.2.1.59 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12364475&form=6&db=m Determination of galectin-3 messenger ribonucleic Acid overexpression in papillary thyroid cancer by quantitative reverse transcription-polymerase chain reaction. causal interaction,diagnostic usage,unassigned 3,1,0 1.2.1.59 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12553051&form=6&db=m Selection of an internal control gene for quantitation of mRNA in colonic tissues. causal interaction,ongoing research,unassigned 4,3,0 1.2.1.59 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27561203&form=6&db=m Selection and validation of reliable reference genes for RT-qPCR analysis in a large cohort of pituitary adenomas. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Adenoma, Bile Duct http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1704820&form=6&db=m Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet. unassigned - 1.2.1.59 Adenoma, Liver Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1704820&form=6&db=m Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet. unassigned - 1.2.1.59 Adenoma, Oxyphilic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32365590&form=6&db=m Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,3,1 1.2.1.59 Adenomatous Polyposis Coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33404293&form=6&db=m BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes. ongoing research,unassigned 1,0 1.2.1.59 Albinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24424828&form=6&db=m Correlations between photosynthetic enzymes, CO2-fixation and plastid structure in an albino mutant of Zea mays L. causal interaction,unassigned 1,0 1.2.1.59 Alkalosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10915225&form=6&db=m Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones. ongoing research,unassigned 2,0 1.2.1.59 alpha-Thalassemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15668518&form=6&db=m A New 5' Terminal Murine GAPDH Exon Identified Using 5'RACE LaNe. diagnostic usage,unassigned 3,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7891898&form=6&db=m Isolation of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) cDNA from the distal half of mouse chromosome 16: further indication of a link between Alzheimer's disease and glycolysis. causal interaction,ongoing research,unassigned 4,2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8614562&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase is over-expressed during apoptotic death of neuronal cultures and is recognized by a monoclonal antibody against amyloid plaques from Alzheimer's brain. causal interaction,unassigned 4,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9779656&form=6&db=m Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11208907&form=6&db=m Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12428732&form=6&db=m Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders? causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12503091&form=6&db=m Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts. causal interaction,ongoing research,unassigned 4,2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14559355&form=6&db=m Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15094325&form=6&db=m Disclosure of a pro-apoptotic glyceraldehyde-3-phosphate dehydrogenase promoter: anti-dementia drugs depress its activation in apoptosis. ongoing research,unassigned 2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15486605&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15746184&form=6&db=m Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein. diagnostic usage,unassigned 1,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16186172&form=6&db=m Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease. causal interaction,unassigned 4,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16832079&form=6&db=m Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease. unassigned - 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17324518&form=6&db=m Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease. causal interaction,ongoing research,unassigned 4,2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18725330&form=6&db=m Non-native glyceraldehyde-3-phosphate dehydrogenase can be an intrinsic component of amyloid structures. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20006611&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase tetramer dissociation and amyloid fibril formation induced by negatively charged membranes. causal interaction,unassigned 3,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20164570&form=6&db=m Oxidatively Modified Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Alzheimer's Disease: Many Pathways to Neurodegeneration. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20864222&form=6&db=m Association and heterogeneity at the GAPDH locus in Alzheimer's disease. causal interaction,unassigned 4,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25022884&form=6&db=m A Proteomic Approach for the Involvement of the GAPDH in Alzheimer Disease in the Blood of Moroccan FAD Cases. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,2,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25246025&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease. causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26359500&form=6&db=m Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-? Amyloidogenesis in Alzheimer Disease. unassigned - 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28087189&form=6&db=m Assessment of GAPDH expression by quantitative real time PCR in blood of Moroccan AD cases. unassigned - 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30254002&form=6&db=m Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31223056&form=6&db=m MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. unassigned - 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32075509&form=6&db=m AMPK activation does not enhance autophagy in neurons in contrast to MTORC1 inhibition: different impact on ?-amyloid clearance. unassigned - 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32469899&form=6&db=m An investigation of the correlation between the S-glutathionylated GAPDH levels in blood and Alzheimer's disease progression. therapeutic application,unassigned 1,0 1.2.1.59 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34341704&form=6&db=m Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-? Aggregation and Cytotoxicity. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18706911&form=6&db=m GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis. causal interaction,unassigned 3,0 1.2.1.59 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18814324&form=6&db=m Determination of protein and RNA expression levels of common housekeeping genes in a mouse model of neurodegeneration. diagnostic usage,unassigned 2,0 1.2.1.59 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23819039&form=6&db=m Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis. causal interaction,ongoing research,unassigned 2,1,0 1.2.1.59 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Anaphylaxis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21624762&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a major allergen in rambutan-induced anaphylaxis. therapeutic application,unassigned 1,0 1.2.1.59 Anemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1395049&form=6&db=m Increased membrane activity of glyceraldehyde 3-phosphate dehydrogenase in erythrocytes of patients with homozygous sickle cell anaemia. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Anemia, Sickle Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1395049&form=6&db=m Increased membrane activity of glyceraldehyde 3-phosphate dehydrogenase in erythrocytes of patients with homozygous sickle cell anaemia. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Anthrax http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20727989&form=6&db=m Surface localized and extracellular Glyceraldehyde-3-phosphate dehydrogenase of Bacillus anthracis is a plasminogen binding protein. ongoing research,unassigned 3,0 1.2.1.59 Arthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1862748&form=6&db=m Oxidation of articular cartilage glyceraldehyde-3-phosphate dehydrogenase (G3PDH) occurs in vivo during carrageenin-induced arthritis. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Arthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24493325&form=6&db=m Gapdh Gene Expression Is Modulated by Inflammatory Arthritis and Is not Suitable for qPCR Normalization. causal interaction,unassigned 3,0 1.2.1.59 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30208760&form=6&db=m Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1. unassigned - 1.2.1.59 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33258403&form=6&db=m Silencing long non-coding RNA NEAT1 attenuates rheumatoid arthritis via the MAPK/ERK signalling pathway by downregulating microRNA-129 and microRNA-204. diagnostic usage,unassigned 1,0 1.2.1.59 Asthenozoospermia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27080476&form=6&db=m Sperm glyceraldehyde 3-phosphate dehydrogenase gene expression in asthenozoospermic spermatozoa. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11415932&form=6&db=m Eotaxin-3 but not eotaxin gene expression is upregulated in asthmatics 24 hours after allergen challenge. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12200519&form=6&db=m beta-Actin and GAPDH housekeeping gene expression in asthmatic airways is variable and not suitable for normalising mRNA levels. causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25659933&form=6&db=m Novel insights in mammalian catalase heme maturation: Effect of NO and thioredoxin-1. causal interaction,ongoing research,therapeutic application,unassigned 3,1,3,0 1.2.1.59 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26051416&form=6&db=m Reference genes for real-time qPCR in leukocytes from asthmatic patients before and after anti-asthma treatment. ongoing research,therapeutic application,unassigned 1,4,0 1.2.1.59 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17597534&form=6&db=m GAPDH is not regulated in human glioblastoma under hypoxic conditions. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,2 1.2.1.59 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20849807&form=6&db=m Selection of reference genes for gene expression studies in astrocytomas. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 1.2.1.59 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25862007&form=6&db=m Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28589519&form=6&db=m Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma. diagnostic usage,unassigned 2,0 1.2.1.59 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30259794&form=6&db=m ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR. diagnostic usage,ongoing research,unassigned 2,2,0 1.2.1.59 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31322210&form=6&db=m E3 ubiquitin ligase siah?1 nuclear accumulation is critical for homocysteine?induced impairment of C6 astroglioma cells. ongoing research,unassigned 4,0 1.2.1.59 Ataxia Telangiectasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31983282&form=6&db=m DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Atherosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24851941&form=6&db=m Expression Profile and Subcellular Localization of GAPDH in the Smooth Muscle Cells of Human Atherosclerotic Plaque: An Immunohistochemical and Ultrastructural Study with Biological Therapeutic Perspectives. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Atrial Fibrillation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29036603&form=6&db=m Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart. ongoing research,unassigned 4,0 1.2.1.59 Autoimmune Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28503176&form=6&db=m Impact of Autoantibodies against Glycolytic Enzymes on Pathogenicity of Autoimmune Retinopathy and Other Autoimmune Disorders. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Autoimmune Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29072876&form=6&db=m Identification of Glyceraldehyde-3-Phosphate and Alcohol Dehydrogenases as Autoantigens in Doberman Hepatitis. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Autoimmune Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33850276&form=6&db=m Natural product 1,2,3,4,6-penta-O-galloyl-?-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase. therapeutic application,unassigned 2,0 1.2.1.59 Avitaminosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8405398&form=6&db=m Vitamin B6 deficiency causes activation of RNA polymerase and general enhancement of gene expression in rat liver. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Azoospermia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12121569&form=6&db=m Quantification of cyclin A1 and glyceraldehyde-3-phosphate dehydrogenase expression in testicular biopsies of infertile patients by fluorescence real-time RT-PCR. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Bacterial Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16843500&form=6&db=m Bacterial endotoxin lipopolysaccharide induces up-regulation of glyceraldehyde-3-phosphate dehydrogenase in rat liver and lungs. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Bacterial Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21220029&form=6&db=m Determination of internal controls for quantitative real time RT-PCR analysis of the effect of Edwardsiella tarda infection on gene expression in turbot (Scophthalmus maximus). diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Bacterial Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22114550&form=6&db=m Inhibition of IL-10 production by maternal antibodies against Group B Streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment. causal interaction,ongoing research,therapeutic application,unassigned 4,1,1,0 1.2.1.59 Bacterial Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28699725&form=6&db=m Evaluation of candidate reference genes for quantitative expression studies in Asian seabass (Lates calcarifer) during ontogenesis and in tissues of healthy and infected fishes. ongoing research,unassigned 3,0 1.2.1.59 beta-Thalassemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15310273&form=6&db=m Analysis of Erythrocyte and Platelet Membrane Proteins in Various Forms of beta-Thalassemia. diagnostic usage,unassigned 1,0 1.2.1.59 Blast Crisis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23150808&form=6&db=m Gene Expression upon Proliferation and Differentiation of Hematopoietic Cells with Ph Chromosome ex vivo. ongoing research,unassigned 3,0 1.2.1.59 Bluetongue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20300993&form=6&db=m Simultaneous detection of bluetongue virus RNA, internal control GAPDH mRNA, and external control synthetic RNA by multiplex real-time PCR. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Brain Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33070462&form=6&db=m Structural change and degradation of cytoskeleton due to the acrolein conjugation with vimentin and actin during brain infarction. causal interaction,unassigned 3,0 1.2.1.59 Brain Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29171745&form=6&db=m Retracted: Resveratrol inhibits oesophageal adenocarcinoma cell proliferation via AMP-activated protein kinase signaling ongoing research,unassigned 2,0 1.2.1.59 Brain Injuries, Traumatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18611280&form=6&db=m Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury. unassigned - 1.2.1.59 Brain Injuries, Traumatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30225299&form=6&db=m Hydrocortisone 21-hemisuccinate did not prevent exogenous GAPDH-induced apoptosis in human neuroblastoma cells. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Brain Injuries, Traumatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31319723&form=6&db=m Inhibition of EphA/Ephrin-A signaling using genetic and pharmacologic approaches improves recovery following traumatic brain injury in mice. unassigned - 1.2.1.59 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23360709&form=6&db=m Disruption of the GluR2/GAPDH complex protects against ischemia-induced neuronal damage. ongoing research,therapeutic application,unassigned 1,1,0 1.2.1.59 Brain Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4279092&form=6&db=m [Enzymes in cerebrospinal fluid (HK, TIM, GAPDH, PGK, enolase, PK, LDH, GPT, ChE) in normal samples, in brain neoplasms and other neurologic diseases] diagnostic usage,unassigned 1,0 1.2.1.59 Brain Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23255924&form=6&db=m Expression of ?-adrenergic receptors in pediatric malignant brain tumors. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7511406&form=6&db=m Comparative expression of fibroblast growth factor mRNAs in benign and malignant breast disease. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7781931&form=6&db=m Measurement of mRNA levels in tumor xenografts with quantitative autoradiography and in situ hybridization. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8202196&form=6&db=m Enzymes of carbohydrate metabolism in human breast carcinoma: relationship with serum hormones. diagnostic usage,unassigned 1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10885609&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase gene expression in human breast cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12119004&form=6&db=m Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1. causal interaction,ongoing research,unassigned 1,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12498774&form=6&db=m Enhanced gene expression in breast cancer cells in vitro and tumors in vivo. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12921788&form=6&db=m Glycolaldehyde induces apoptosis in a human breast cancer cell line. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16204465&form=6&db=m Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16326072&form=6&db=m Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,2,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17108228&form=6&db=m Concentrations of circulating RNA from healthy donors and cancer patients estimated by different methods. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17347775&form=6&db=m Quantitative detection of circulating epithelial cells by Q-RT-PCR. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17391528&form=6&db=m Estrogen receptor alpha (ER alpha) mRNA copy numbers in immunohistochemically ER alpha-positive-, and negative breast cancer tissues. diagnostic usage,unassigned 1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18076071&form=6&db=m Nitroxyl inhibits breast tumor growth and angiogenesis. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,3,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18421914&form=6&db=m [Breast cancer diagnostics based on extracellular DNA and RNA circulating in blood] diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18629778&form=6&db=m Parallel assessment of circulatory cell-free DNA by PCR and nucleosomes by ELISA in breast tumors. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19544972&form=6&db=m Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20664973&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a surface associated antigen on human breast cancer cell lines MACL-1 and MGSO-3. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,4 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21338575&form=6&db=m Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. ongoing research,unassigned 4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22318550&form=6&db=m Gene expression and pathologic response to neoadjuvant chemotherapy in breast cancer. diagnostic usage,ongoing research,unassigned 1,2,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22552268&form=6&db=m Identification of potential prognostic biomarkers for node-negative breast tumours by proteomic analysis: a multicentric 2004 national PHRC study. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22847419&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,2,1 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22874552&form=6&db=m LAMP2A overexpression in breast tumors promotes cancer cell survival via chaperone-mediated autophagy. causal interaction,ongoing research,therapeutic application,unassigned 3,1,1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23331018&form=6&db=m Proteomics using mammospheres as a model system to identify proteins deregulated in breast cancer stem cells. unassigned - 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24924632&form=6&db=m Fatty acid-bearing albumin but not fatty acid-depleted albumin induces HIF-1 activation in human renal proximal tubular epithelial cell line HK-2. unassigned - 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24970821&form=6&db=m RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth. unassigned - 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25445497&form=6&db=m Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25479875&form=6&db=m Single-cell multiple gene expression analysis based on single-molecule-detection microarray assay for multi-DNA determination. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25620657&form=6&db=m Autophagy-related prognostic signature for breast cancer. causal interaction,diagnostic usage,ongoing research,unassigned 2,4,3,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27099857&form=6&db=m Alteration of GLIS3 gene expression pattern in patients with breast cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,4,4,4 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27194954&form=6&db=m A microfluidic approach to parallelized transcriptional profiling of single cells. ongoing research,unassigned 4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28332571&form=6&db=m Profiling protein expression in circulating tumour cells using microfluidic western blotting. unassigned - 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28476800&form=6&db=m Heterogeneous Cell Types in Single-cell-derived Clones of MCF7 and MDA-MB-231 Cells. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28686014&form=6&db=m Efficient Dual siRNA and Drug Delivery Using Engineered Lipoproteoplexes. therapeutic application,unassigned 1,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30174558&form=6&db=m Cytosolic and Transmembrane Protein Extraction Methods of Breast and Ovarian Cancer Cells: A Comparative Study. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30311703&form=6&db=m Shortening of apparent transverse relaxation time of inorganic phosphate as a breast cancer biomarker. unassigned - 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32724387&form=6&db=m AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33630196&form=6&db=m Overexpression of Stat3 increases circulating cfDNA in breast cancer. diagnostic usage,unassigned 4,0 1.2.1.59 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34073074&form=6&db=m Tissue-Specific Warburg Effect in Breast Cancer and Cancer-Associated Adipose Tissue-Relationship between AMPK and Glycolysis. causal interaction,unassigned 3,0 1.2.1.59 Brucellosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20876984&form=6&db=m Brucella abortus L7/L12 recombinant protein induces strong Th1 response in acute brucellosis patients. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,2 1.2.1.59 Bulbo-Spinal Atrophy, X-Linked http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8872471&form=6&db=m Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 1.2.1.59 Bulbo-Spinal Atrophy, X-Linked http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Burkitt Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7615095&form=6&db=m The mode of actions of glyceraldehyde-3-phosphate dehydrogenase identified as an immunoglobulin production stimulating factor. ongoing research,unassigned 4,0 1.2.1.59 ca2+/calmodulin-dependent protein kinase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32485269&form=6&db=m Hypomorphic CAMKK2 in EA.hy926 endothelial cells causes abnormal transferrin trafficking, iron homeostasis and glucose metabolism. causal interaction,unassigned 4,0 1.2.1.59 Candidiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9573088&form=6&db=m The cell wall-associated glyceraldehyde-3-phosphate dehydrogenase of Candida albicans is also a fibronectin and laminin binding protein. causal interaction,unassigned 1,0 1.2.1.59 Candidiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10219595&form=6&db=m Clinical strains of Candida albicans express the surface antigen glyceraldehyde 3-phosphate dehydrogenase in vitro and in infected tissues. causal interaction,ongoing research,unassigned 1,2,0 1.2.1.59 Candidiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16779630&form=6&db=m Evaluation of the usefulness of anti-glyceraldehyde-3-phosphate dehydrogenase antibodies as a treatment for invasive candidiasis in a murine model. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 1.2.1.59 Candidiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18725625&form=6&db=m Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis. ongoing research,unassigned 2,0 1.2.1.59 Candidiasis, Invasive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16779630&form=6&db=m Evaluation of the usefulness of anti-glyceraldehyde-3-phosphate dehydrogenase antibodies as a treatment for invasive candidiasis in a murine model. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2765128&form=6&db=m Increased expression of glycolysis-associated genes in oncogene-transformed and growth-accelerated states. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3089988&form=6&db=m Similarity between glyceraldehyde-3-phosphate dehydrogenase and a 37,000-dalton protein which is abundantly expressed in human lung cancers. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7612002&form=6&db=m Transcriptional regulation of glyceraldehyde-3-phosphate dehydrogenase by 2,3,7,8-tetrachlorodibenzo-p-dioxin. causal interaction,diagnostic usage,unassigned 1,3,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9468581&form=6&db=m Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,3 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12438266&form=6&db=m The bioenergetic signature of cancer: a marker of tumor progression. causal interaction,ongoing research,unassigned 1,4,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17072346&form=6&db=m GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. causal interaction,therapeutic application,unassigned 1,3,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18317805&form=6&db=m Selection of reference genes for real-time PCR in human hepatocellular carcinoma tissues. causal interaction,diagnostic usage,unassigned 1,4,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19779498&form=6&db=m Novel roles for GAPDH in cell death and carcinogenesis. causal interaction,unassigned 2,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21895736&form=6&db=m GAPDH: A common enzyme with uncommon functions. causal interaction,unassigned 1,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22964488&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,4,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23331018&form=6&db=m Proteomics using mammospheres as a model system to identify proteins deregulated in breast cancer stem cells. unassigned - 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23445303&form=6&db=m Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a therapeutic target. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,4 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28387968&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase. causal interaction,ongoing research,unassigned 3,4,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30209795&form=6&db=m Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases. causal interaction,ongoing research,unassigned 3,2,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31658047&form=6&db=m Novel protein and immune response markers of human serous tubal intraepithelial carcinoma of the ovary. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32646244&form=6&db=m Moonlighting glyceraldehyde-3-phosphate dehydrogenase: posttranslational modification, protein and nucleic acid interactions in normal cells and in human pathology. causal interaction,ongoing research,unassigned 3,1,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33615312&form=6&db=m Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review. causal interaction,unassigned 1,0 1.2.1.59 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34249897&form=6&db=m Sperm-Specific Glycolysis Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Regulated by Transcription Factor SOX10 to Promote Uveal Melanoma Tumorigenesis. causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1848480&form=6&db=m Histochemical profile of mouse hepatocellular adenomas and carcinomas induced by a single dose of diethylnitrosamine. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2876545&form=6&db=m Correlative histochemical studies on preneoplastic and neoplastic lesions in the kidney of rats treated with nitrosamines. causal interaction,unassigned 1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2879649&form=6&db=m Sequential histochemical and morphometric studies on preneoplastic and neoplastic lesions induced in rat colon by 1,2-dimethylhydrazine. unassigned - 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3675570&form=6&db=m Reversible oxidation of glyceraldehyde 3-phosphate dehydrogenase thiols in human lung carcinoma cells by hydrogen peroxide. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4030504&form=6&db=m Specific inhibition of glyceraldehyde-3-phosphate dehydrogenase by koningic acid (heptelidic acid). ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6456251&form=6&db=m Interaction of cytotoxic antibiotic dactylarin with glycolytic thiol enzymes in Ehrlich ascites carcinoma cells. unassigned - 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6591771&form=6&db=m Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis. unassigned - 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7524903&form=6&db=m Expression of human prostatic acid phosphatase and prostate specific antigen genes in neoplastic and benign tissues. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7671226&form=6&db=m Alteration of glyceraldehyde-3-phosphate dehydrogenase activity and messenger RNA content by androgen in human prostate carcinoma cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9018118&form=6&db=m Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9826470&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,4 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10328219&form=6&db=m Rapid screening of specific changes in mRNA in thyroid carcinomas by sequence specific-differential display: decreased expression of acid ceramidase mRNA in malignant and benign thyroid tumors. causal interaction,diagnostic usage,unassigned 4,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10336623&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase from Ehrlich ascites carcinoma cells its possible role in the high glycolysis of malignant cells. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10645776&form=6&db=m Antisense oligodeoxynucleotide of glyceraldehyde-3-phosphate dehydrogenase gene inhibits cell proliferation and induces apoptosis in human cervical carcinoma cell lines. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,4 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10897012&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11076659&form=6&db=m Gene expression profiles in thyroid carcinomas. diagnostic usage,ongoing research,unassigned 2,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11732997&form=6&db=m Identification of a critical lysine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cell. Comparison with the rabbit muscle enzyme. diagnostic usage,ongoing research,therapeutic application,unassigned 2,3,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12036445&form=6&db=m The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12438266&form=6&db=m The bioenergetic signature of cancer: a marker of tumor progression. causal interaction,ongoing research,unassigned 1,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12926130&form=6&db=m RT-PCR amplification of RNA extracted from formalin-fixed, paraffin-embedded oral cancer sections: analysis of p53 pathway. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17190429&form=6&db=m [Quantitative analysis of epidermal growth factor receptor mRNA in laryngeal carcinoma by reverse transcription-real time polymerase chain reaction with TagMan probe] diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19372559&form=6&db=m Chromatin-associated proteins HMGB1/2 and PDIA3 trigger cellular response to chemotherapy-induced DNA damage. ongoing research,unassigned 3,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19628630&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines. causal interaction,ongoing research,therapeutic application,unassigned 3,4,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19650912&form=6&db=m Reference gene selection for head and neck squamous cell carcinoma gene expression studies. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20450584&form=6&db=m [Proteomic identification and comparison of differentiation-related proteins in gastric carcinoma cell lines] diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21749859&form=6&db=m Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells. causal interaction,ongoing research,unassigned 3,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22470562&form=6&db=m Oxidative stress in HPV-driven viral carcinogenesis: redox proteomics analysis of HPV-16 dysplastic and neoplastic tissues. causal interaction,unassigned 1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22668015&form=6&db=m Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,3 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22896902&form=6&db=m Evidence for the presence of a critical histidine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cells. diagnostic usage,unassigned 3,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23445303&form=6&db=m Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a therapeutic target. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,4 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24457517&form=6&db=m Identification of reference genes for qRT-PCR in human lung squamous-cell carcinoma by RNA-Seq. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25434674&form=6&db=m Identification of suitable reference genes for investigating gene expression in human gallbladder carcinoma using reverse transcription quantitative polymerase chain reaction. diagnostic usage,unassigned 1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25691059&form=6&db=m Cell-specific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25944651&form=6&db=m Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26452026&form=6&db=m High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma. causal interaction,diagnostic usage,unassigned 1,3,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26911935&form=6&db=m Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27889881&form=6&db=m Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma. diagnostic usage,unassigned 1,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29467444&form=6&db=m Evaluation of digital real-time PCR assay as a molecular diagnostic tool for single-cell analysis. diagnostic usage,ongoing research,unassigned 4,2,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31522588&form=6&db=m Circ_0015756 promotes proliferation, invasion and migration by microRNA-7-dependent inhibition of FAK in hepatocellular carcinoma. unassigned - 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32365590&form=6&db=m Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,3,1 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32543008&form=6&db=m Elevated GAPDH Expression is Associated with the Proliferation and Invasion of Lung and Esophageal Squamous Cell Carcinomas. causal interaction,unassigned 4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32923135&form=6&db=m Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,2,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32944178&form=6&db=m miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas. ongoing research,unassigned 2,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33092235&form=6&db=m Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34115239&form=6&db=m Exploring polyps to colon carcinoma voyage: can blocking the crossroad halt the sequence? causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Carcinoma, Basal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32944178&form=6&db=m miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas. ongoing research,unassigned 2,0 1.2.1.59 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4332723&form=6&db=m Properties of the glyceraldehyde-3-phosphate dehydrogenase from Ehrlich ascites tumor cells. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7584597&form=6&db=m Interaction of calcyclin and its cyanogen bromide fragments with annexin II and glyceraldehyde 3-phosphate dehydrogenase. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2839830&form=6&db=m Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8666326&form=6&db=m Comparison of glyceraldehyde-3-phosphate dehydrogenase and 28s-ribosomal RNA gene expression in human hepatocellular carcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9468581&form=6&db=m Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,3 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9472111&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase mRNA expression in hepatocellular carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,2,1 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11882413&form=6&db=m High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19144146&form=6&db=m Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,4 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19534685&form=6&db=m Targets of 3-Bromopyruvate, a New, Energy Depleting, Anticancer Agent. causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22189680&form=6&db=m p53 is not necessary for nuclear translocation of GAPDH during NO-induced apoptosis. causal interaction,unassigned 1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22357885&form=6&db=m Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,3,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22964488&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,4,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23811755&form=6&db=m Evaluation of potential reference genes for qRT-PCR studies in human hepatoma cell lines treated with TNF-?. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,3 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24840721&form=6&db=m Cationic lipid nanodisks as an siRNA delivery vehicle. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26136865&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28258188&form=6&db=m Lysine post-translational modification of glyceraldehyde-3-phosphate dehydrogenase regulates hepatic and systemic metabolism. therapeutic application,unassigned 1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28387968&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase. causal interaction,ongoing research,unassigned 3,4,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28479730&form=6&db=m Anti-hepatocarcinogenic and Anti-oxidant Effects of Mangrove Plant Scyphiphora hydrophyllacea. unassigned - 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30786811&form=6&db=m The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31239764&form=6&db=m Nuclear GAPDH is vital for hypoxia-induced hepatic stellate cell apoptosis and is indicative of aggressive hepatocellular carcinoma behavior. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31522588&form=6&db=m Circ_0015756 promotes proliferation, invasion and migration by microRNA-7-dependent inhibition of FAK in hepatocellular carcinoma. unassigned - 1.2.1.59 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31564201&form=6&db=m Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway. diagnostic usage,unassigned 3,0 1.2.1.59 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16319328&form=6&db=m Choice of endogenous control for gene expression in nonsmall cell lung cancer. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21749859&form=6&db=m Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells. causal interaction,ongoing research,unassigned 3,4,0 1.2.1.59 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31232177&form=6&db=m Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPK? signaling in STK11 mutant lung cancer. ongoing research,unassigned 1,0 1.2.1.59 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31448672&form=6&db=m PAQR3 suppresses the growth of non-small cell lung cancer cells via modulation of EGFR-mediated autophagy. ongoing research,unassigned 1,0 1.2.1.59 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32923135&form=6&db=m Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,2,0 1.2.1.59 Carcinoma, Ovarian Epithelial http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17442564&form=6&db=m Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Carcinoma, Ovarian Epithelial http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19331211&form=6&db=m Association of metastin/a G-protein-coupled receptor signaling and Down syndrome critical region 1 in epithelial ovarian cancer. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Carcinoma, Papillary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10328219&form=6&db=m Rapid screening of specific changes in mRNA in thyroid carcinomas by sequence specific-differential display: decreased expression of acid ceramidase mRNA in malignant and benign thyroid tumors. causal interaction,diagnostic usage,unassigned 4,4,0 1.2.1.59 Carcinoma, Papillary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12364475&form=6&db=m Determination of galectin-3 messenger ribonucleic Acid overexpression in papillary thyroid cancer by quantitative reverse transcription-polymerase chain reaction. causal interaction,diagnostic usage,unassigned 3,1,0 1.2.1.59 Carcinoma, Renal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10897012&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Carcinoma, Renal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31522588&form=6&db=m Circ_0015756 promotes proliferation, invasion and migration by microRNA-7-dependent inhibition of FAK in hepatocellular carcinoma. unassigned - 1.2.1.59 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19650912&form=6&db=m Reference gene selection for head and neck squamous cell carcinoma gene expression studies. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22668015&form=6&db=m Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,3 1.2.1.59 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25944651&form=6&db=m Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 1.2.1.59 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26452026&form=6&db=m High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma. causal interaction,diagnostic usage,unassigned 1,3,0 1.2.1.59 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27889881&form=6&db=m Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma. diagnostic usage,unassigned 1,0 1.2.1.59 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32543008&form=6&db=m Elevated GAPDH Expression is Associated with the Proliferation and Invasion of Lung and Esophageal Squamous Cell Carcinomas. causal interaction,unassigned 4,0 1.2.1.59 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32944178&form=6&db=m miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas. ongoing research,unassigned 2,0 1.2.1.59 Carcinoma, Transitional Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9018118&form=6&db=m Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33329019&form=6&db=m Identification of Potentially Relevant Genes for Excessive Exercise-Induced Pathological Cardiac Hypertrophy in Zebrafish. unassigned - 1.2.1.59 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9788826&form=6&db=m Differential expression of tissue inhibitors of metalloproteinases in the failing human heart. ongoing research,unassigned 3,0 1.2.1.59 Cardiomyopathy, Alcoholic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28962519&form=6&db=m From the Cover: Alcohol Inhibition of the Enzymatic Activity of Glyceraldehyde 3-Phosphate Dehydrogenase Impairs Cardiac Glucose Utilization, Contributing to Alcoholic Cardiomyopathy. causal interaction,unassigned 1,0 1.2.1.59 Cardiomyopathy, Dilated http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9788826&form=6&db=m Differential expression of tissue inhibitors of metalloproteinases in the failing human heart. ongoing research,unassigned 3,0 1.2.1.59 Cardiomyopathy, Dilated http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10189359&form=6&db=m Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium. diagnostic usage,ongoing research,unassigned 1,2,0 1.2.1.59 Cardiotoxicity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30413070&form=6&db=m Toxicity Evaluation and Biomarker Selection with Validated Reference Gene in Embryonic Zebrafish Exposed to Mitoxantrone. diagnostic usage,unassigned 3,0 1.2.1.59 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22940604&form=6&db=m Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1. causal interaction,unassigned 1,0 1.2.1.59 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9196396&form=6&db=m Changes in calpain II mRNA in young rat lens during maturation and cataract formation. causal interaction,diagnostic usage,ongoing research,unassigned 2,1,3,0 1.2.1.59 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15183105&form=6&db=m Revival of inactive glyceraldehyde 3-phosphate dehydrogenase in human cataract lenses by reduction. ongoing research,unassigned 1,0 1.2.1.59 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17093401&form=6&db=m Thioredoxin, thioredoxin reductase, and alpha-crystallin revive inactivated glyceraldehyde 3-phosphate dehydrogenase in human aged and cataract lens extracts. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,2,1 1.2.1.59 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21436267&form=6&db=m Proteomic analysis of human age-related nuclear cataracts and normal lens nuclei. unassigned - 1.2.1.59 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25614994&form=6&db=m "Moonlighting" GAPDH Protein Localizes with AMPA Receptor GluA2 and L1 Axonal Cell Adhesion Molecule at Fiber Cell Borders in the Lens. ongoing research,unassigned 3,0 1.2.1.59 Central Nervous System Protozoal Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27426132&form=6&db=m Expression, purification, enzymatic characterization and crystallization of glyceraldehyde-3-phosphate dehydrogenase from Naegleria gruberi, the first one from phylum Percolozoa. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Chagas Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9580189&form=6&db=m Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase: structure, catalytic mechanism and targeted inhibitor design. therapeutic application,unassigned 1,0 1.2.1.59 Chagas Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14635721&form=6&db=m 3D QSAR studies on binding affinities of coumarin natural products for glycosomal GAPDH of Trypanosoma cruzi. ongoing research,unassigned 2,0 1.2.1.59 Chagas Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16297925&form=6&db=m Development and characterization of an immobilized enzyme reactor (IMER) based on human glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies. causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Chagas Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19254846&form=6&db=m Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Chagas Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21138769&form=6&db=m Expression, purification and kinetic characterization of His-tagged glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Chagas Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24358945&form=6&db=m Integration of methods in cheminformatics and biocalorimetry for the design of trypanosomatid enzyme inhibitors. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Cholesteatoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32915926&form=6&db=m Extensive qPCR analysis reveals altered gene expression in middle ear mucosa from cholesteatoma patients. ongoing research,unassigned 2,0 1.2.1.59 Chordoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28695047&form=6&db=m Validation of reference genes in human chordoma. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,1,0 1.2.1.59 Choriocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16467170&form=6&db=m Nuclear beta-catenin and Ki-67 expression in choriocarcinoma and its pre-malignant form. diagnostic usage,unassigned 4,0 1.2.1.59 Choriocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24375405&form=6&db=m Transglutaminase 2-dependent deamidation of glyceraldehyde-3-phosphate dehydrogenase promotes trophoblastic cell fusion. ongoing research,unassigned 4,0 1.2.1.59 Coinfection http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23084627&form=6&db=m Immune response of turbot (Scophthalmus maximus L.) to a broad spectrum vaccine candidate, recombinant glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda. causal interaction,therapeutic application,unassigned 2,4,0 1.2.1.59 Coinfection http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26697991&form=6&db=m Molecular characterization of native Australian trypanosomes in quokka (Setonix brachyurus) populations from Western Australia. unassigned - 1.2.1.59 Coinfection http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29624743&form=6&db=m Absence of interaction between porcine endogenous retrovirus and porcine cytomegalovirus in pig-to-baboon renal xenotransplantation in vivo. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Coinfection http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34133917&form=6&db=m Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 1.2.1.59 Colitis, Ulcerative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23282302&form=6&db=m Enhanced intramucosal cytotoxic lymphocyte gene expression in ulcerative colitis. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 1.2.1.59 Colitis, Ulcerative http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32424999&form=6&db=m Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,2 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3180054&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11282488&form=6&db=m Simple quantitative assay of alpha-fetoprotein mRNA in liver tissue using the real-time detection polymerase chain reaction assay - its application for clinical use. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12553051&form=6&db=m Selection of an internal control gene for quantitation of mRNA in colonic tissues. causal interaction,ongoing research,unassigned 4,3,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19144146&form=6&db=m Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,4 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22350014&form=6&db=m Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25944804&form=6&db=m Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,3,4 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27339468&form=6&db=m Serum availability affects expression of common house-keeping genes in colon adenocarcinoma cell lines: implications for quantitative real-time PCR studies. ongoing research,unassigned 2,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27878251&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression. causal interaction,ongoing research,unassigned 4,1,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28184026&form=6&db=m Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin. causal interaction,ongoing research,therapeutic application,unassigned 1,1,1,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30666129&form=6&db=m Celastrol inhibits colorectal cancer through TGF-?1/Smad signaling. ongoing research,unassigned 4,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30949321&form=6&db=m Gene expression profile analysis of colon cancer grade II into grade III transition by using system biology. diagnostic usage,ongoing research,unassigned 1,2,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31901813&form=6&db=m Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells. ongoing research,unassigned 4,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32539222&form=6&db=m Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage. ongoing research,therapeutic application,unassigned 3,2,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33092235&form=6&db=m Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33723275&form=6&db=m Gossypol decreased cell viability and down-regulated the expression of a number of genes in human colon cancer cells. therapeutic application,unassigned 1,0 1.2.1.59 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33758077&form=6&db=m AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer. therapeutic application,unassigned 2,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12181091&form=6&db=m [Expression of osteopontin mRNA and its protein in colorectal cancer and liver metastatic tissues] diagnostic usage,ongoing research,unassigned 2,4,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17652962&form=6&db=m Increased translocator protein (TSPO) mRNA levels in colon but not in rectum carcinoma. diagnostic usage,ongoing research,therapeutic application,unassigned 2,3,1,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20122155&form=6&db=m Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer. unassigned - 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20859286&form=6&db=m Is GAPDH a relevant housekeeping gene for normalisation in colorectal cancer experiments? unassigned - 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22350014&form=6&db=m Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22991145&form=6&db=m Comprehensive fluorogenic derivatization-liquid chromatography/tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26541605&form=6&db=m Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. unassigned - 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26586769&form=6&db=m Vitamin C Targets GAPDH to Kill KRAS- and BRAF-Mutant Cancer Cells. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29067439&form=6&db=m Apolipoprotein M increases the expression of vitamin D receptor mRNA in colorectal cancer cells detected with duplex fluorescence reverse transcription-quantitative polymerase chain reaction. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29780883&form=6&db=m Vitamin C, a Multi-Tasking Molecule, Finds a Molecular Target in Killing Cancer Cells. unassigned - 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30581507&form=6&db=m Correlation study of GAPDH, Bcl-2, and Bax protein immunoexpression in patients with colorectal adenocarcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,3 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31901813&form=6&db=m Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells. ongoing research,unassigned 4,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32424999&form=6&db=m Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,2 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33092235&form=6&db=m Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33345684&form=6&db=m Ropivacaine inhibits the proliferation and migration of colorectal cancer cells through ITGB1. unassigned - 1.2.1.59 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33398999&form=6&db=m Antitumor Activity of Asperphenin B by Induction of Apoptosis and Regulation of Glyceraldehyde-3-phosphate Dehydrogenase in Human Colorectal Cancer Cells. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Congenital Hypothyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5080320&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase activity in developing brain during experimental cretinism. ongoing research,unassigned 2,0 1.2.1.59 Connective Tissue Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15262899&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase is a novel autoantigen leading autoimmune responses to proliferating cell nuclear antigen multiprotein complexes in lupus patients. causal interaction,unassigned 1,0 1.2.1.59 Contracture http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2381520&form=6&db=m Metabolic myopathy produced by acute inhibition of glyceraldehyde-3-phosphate dehydrogenase with ortho-iodosobenzoic acid. causal interaction,ongoing research,therapeutic application,unassigned 2,4,2,0 1.2.1.59 Contracture http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3225621&form=6&db=m Metabolic myopathy produced by dinitrofluorobenzene inhibition of creatine phosphokinase. ongoing research,therapeutic application,unassigned 2,2,0 1.2.1.59 COVID-19 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33185982&form=6&db=m Interferon-stimulated gene products as regulators of central carbon metabolism. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 COVID-19 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33539530&form=6&db=m Diseasome and comorbidities complexities of SARS-CoV-2 infection with common malignant diseases. therapeutic application,unassigned 1,0 1.2.1.59 Crohn Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24859296&form=6&db=m Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies. unassigned - 1.2.1.59 Crohn Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32424999&form=6&db=m Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,2 1.2.1.59 Cryptosporidiosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34208228&form=6&db=m Cryptosporidiosis Modulates the Gut Microbiome and Metabolism in a Murine Infection Model. unassigned - 1.2.1.59 Cystadenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27141900&form=6&db=m [Study of the genes correlated with cyst calcification in patients with cystic echinococcosis]. diagnostic usage,ongoing research,unassigned 2,1,0 1.2.1.59 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9124353&form=6&db=m Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation. diagnostic usage,unassigned 3,0 1.2.1.59 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25092993&form=6&db=m Decreased basal chloride secretion and altered cystic fibrosis transmembrane conductance regulatory protein, Villin, GLUT5 protein expression in jejunum from leptin-deficient mice. ongoing research,unassigned 3,0 1.2.1.59 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10072900&form=6&db=m Effect of mebendazole and praziquantel on glucosephosphate isomerase and glyceraldehydephosphate dehydrogenase in Echinococcus granulosus cyst wall harbored in mice. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,2,2,1 1.2.1.59 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23058231&form=6&db=m Differential dissolved protein expression throughout the life cycle of Giardia lamblia. unassigned - 1.2.1.59 Dehydration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7948905&form=6&db=m Dehydration and ABA increase mRNA levels and enzyme activity of cytosolic GAPDH in the resurrection plant Craterostigma plantagineum. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Dehydration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16878554&form=6&db=m [Activity of NADP-dependent glyceraldehyde-phosphate dehydrogenase and phosphoenolpyruvate carboxylase in wheat leaves under water stress] causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Dehydration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24987730&form=6&db=m Validation of novel reference genes for reverse transcription quantitative real-time PCR in drought-stressed sugarcane. ongoing research,unassigned 2,0 1.2.1.59 Dehydration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33368595&form=6&db=m Mind the GAP: Purification and characterization of urea resistant GAPDH during extreme dehydration. ongoing research,unassigned 2,0 1.2.1.59 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19885726&form=6&db=m Recombinant dengue virus-like particles from Pichia pastoris: efficient production and immunological properties. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26378175&form=6&db=m Dengue Virus NS1 Protein Modulates Cellular Energy Metabolism by Increasing Glyceraldehyde-3-Phosphate Dehydrogenase Activity. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28548037&form=6&db=m Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 1.2.1.59 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30071880&form=6&db=m Endogenous gene selection for relative quantification PCR and IL6 transcript levels in the PBMC's of severe and non-severe dengue cases. diagnostic usage,ongoing research,therapeutic application,unassigned 1,3,1,0 1.2.1.59 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30351952&form=6&db=m Host Proteins Identified in Extracellular Viral Particles as Targets for Broad-Spectrum Antiviral Inhibitors. therapeutic application,unassigned 3,0 1.2.1.59 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30804377&form=6&db=m Dengue virus nonstructural 3 protein interacts directly with human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and reduces its glycolytic activity. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33890542&form=6&db=m HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons. unassigned - 1.2.1.59 Dermatitis, Atopic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15014952&form=6&db=m Relative importance of IL-4 and IL-13 in lesional skin of atopic dermatitis. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Dermatitis, Atopic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18824265&form=6&db=m Reference genes for canine skin when using quantitative real-time PCR. ongoing research,unassigned 4,0 1.2.1.59 Dermatitis, Contact http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10416274&form=6&db=m Quantitative polymerase chain reaction using an external control mRNA for determination of gene expression in a heterogeneous cell population. causal interaction,ongoing research,unassigned 1,3,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12527413&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes. causal interaction,unassigned 1,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12716756&form=6&db=m Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos. causal interaction,unassigned 4,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15633931&form=6&db=m [Molecular pathophysiology of late complications diabetes mellitus--hyperglycemia-induced changes] causal interaction,unassigned 2,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15962096&form=6&db=m The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16037232&form=6&db=m Methylglyoxal can modify GAPDH activity and structure. causal interaction,unassigned 1,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17934141&form=6&db=m Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress. causal interaction,unassigned 1,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18448829&form=6&db=m Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes. causal interaction,unassigned 4,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18852331&form=6&db=m Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy. causal interaction,unassigned 4,0 1.2.1.59 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27372863&form=6&db=m Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance. causal interaction,therapeutic application,unassigned 1,4,0 1.2.1.59 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11237753&form=6&db=m Fudenine, a C-terminal truncated rat homologue of mouse prominin, is blood glucose-regulated and can up-regulate the expression of GAPDH. causal interaction,unassigned 4,0 1.2.1.59 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25970163&form=6&db=m The Shepherds' Tale: A Genome-Wide Study across 9 Dog Breeds Implicates Two Loci in the Regulation of Fructosamine Serum Concentration in Belgian Shepherds. causal interaction,unassigned 4,0 1.2.1.59 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26255202&form=6&db=m Oxidation of glyceraldehyde-3-phosphate dehydrogenase decreases sperm motility in diabetes mellitus. causal interaction,ongoing research,unassigned 1,1,0 1.2.1.59 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12527413&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes. causal interaction,unassigned 1,0 1.2.1.59 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10028053&form=6&db=m Metabolism of [1,3-(13)C]glycerol-1,2,3-tris(methylsuccinate) and glycerol-1,2,3-tris(methyl[2,3-(13)C]succinate) in hepatocytes from Goto-Kakizaki rats. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12527413&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes. causal interaction,unassigned 1,0 1.2.1.59 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20408053&form=6&db=m Assessment of cell-free DNA with microvascular complication of type II diabetes mellitus, using PCR and ELISA. causal interaction,diagnostic usage,unassigned 3,4,0 1.2.1.59 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20964553&form=6&db=m Succination of proteins in diabetes. causal interaction,ongoing research,unassigned 2,1,0 1.2.1.59 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25189828&form=6&db=m [Contribution to the study of glyceraldehyde-3-phosphate dehydrogenase in patients with type 2 diabetes]. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 1.2.1.59 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28608282&form=6&db=m Poly(ADP-ribosylated) proteins in mononuclear cells from patients with type 2 diabetes identified by proteomic studies. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Diabetic Angiopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19210748&form=6&db=m Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction. causal interaction,unassigned 3,0 1.2.1.59 Diabetic Nephropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19997558&form=6&db=m Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications. causal interaction,unassigned 3,0 1.2.1.59 Diabetic Retinopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15111614&form=6&db=m Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells. causal interaction,unassigned 2,0 1.2.1.59 Diabetic Retinopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18852331&form=6&db=m Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy. causal interaction,unassigned 4,0 1.2.1.59 Diabetic Retinopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19875652&form=6&db=m Glyceraldehyde 3 phosphate dehydrogenase in retinal microvasculature: Implications for the development and progression of diabetic retinopathy. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Diabetic Retinopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20408053&form=6&db=m Assessment of cell-free DNA with microvascular complication of type II diabetes mellitus, using PCR and ELISA. causal interaction,diagnostic usage,unassigned 3,4,0 1.2.1.59 Diabetic Retinopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25176140&form=6&db=m High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Dirofilariasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27198784&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase and galectin from Dirofilaria immitis participate in heartworm disease endarteritis via plasminogen/plasmin system. ongoing research,unassigned 2,0 1.2.1.59 Distemper http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11960638&form=6&db=m Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7891898&form=6&db=m Isolation of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) cDNA from the distal half of mouse chromosome 16: further indication of a link between Alzheimer's disease and glycolysis. causal interaction,ongoing research,unassigned 4,2,0 1.2.1.59 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10025719&form=6&db=m Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down's syndrome. diagnostic usage,unassigned 3,0 1.2.1.59 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16144565&form=6&db=m [Application of real-time fluorescence quantitative polymerase chain reaction techniques for prenatal diagnosis of Down syndrome] diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17681920&form=6&db=m [Rapid diagnosis of Down's syndrome by multiplex real-time fluorescence relative quantitative PCR] diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19439973&form=6&db=m Sensitivity of DCSR3/GAPDH Ratio Using Quantitative Real-Time PCR in the Rapid Prenatal Diagnosis for Down Syndrome. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Dupuytren Contracture http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8893764&form=6&db=m Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Dwarfism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19675149&form=6&db=m Plastidial glyceraldehyde-3-phosphate dehydrogenase deficiency leads to altered root development and affects the sugar and amino Acid balance in Arabidopsis. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Dysentery, Bacillary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32880588&form=6&db=m Characterization and structure of glyceraldehyde-3-phosphate dehydrogenase type 1 from Escherichia coli. causal interaction,therapeutic application,unassigned 1,4,0 1.2.1.59 Encephalitis, Japanese http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19368702&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3' ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein. causal interaction,therapeutic application,unassigned 2,1,0 1.2.1.59 Encephalitis, Tick-Borne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25389513&form=6&db=m Cloning and Expression of Recombinant Tick-Borne Encephalitis Virus-like Particles in Pichia pastoris. ongoing research,unassigned 3,0 1.2.1.59 Encephalomyelitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30208760&form=6&db=m Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1. unassigned - 1.2.1.59 Encephalomyelitis, Autoimmune, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30208760&form=6&db=m Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1. unassigned - 1.2.1.59 Endarteritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27198784&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase and galectin from Dirofilaria immitis participate in heartworm disease endarteritis via plasminogen/plasmin system. ongoing research,unassigned 2,0 1.2.1.59 Endocarditis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11269731&form=6&db=m pH-regulated secretion of a glyceraldehyde-3-phosphate dehydrogenase from Streptococcus gordonii FSS2: purification, characterization, and cloning of the gene encoding this enzyme. ongoing research,unassigned 3,0 1.2.1.59 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17875279&form=6&db=m [Dual role for the glycolytic enzyme GAPDH in GABAergic neurotransmission and in human epilepsy] ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20191118&form=6&db=m Quantitative characterization of regional differences in the GABAA-receptor alpha1-subunit mRNA expression in the rat brain. unassigned - 1.2.1.59 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29489588&form=6&db=m Disruption of the GluA2/GAPDH complex using TAT-GluA2NT1-3-2 peptide protects against AMPAR-mediated excitotoxicity after epilepsy. unassigned - 1.2.1.59 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31759082&form=6&db=m Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease. therapeutic application,unassigned 1,0 1.2.1.59 Epilepsy, Absence http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28719803&form=6&db=m Elevated sterol regulatory elementary binding protein 1 and GluA2 levels in the hippocampal nuclear fraction of Genetic Absence Epilepsy Rats from Strasbourg. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 1.2.1.59 Esophageal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24527027&form=6&db=m Overexpression of FOXO3, MYD88, and GAPDH Identified by Suppression Subtractive Hybridization in Esophageal Cancer Is Associated with Autophagy. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Esophageal Squamous Cell Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27889881&form=6&db=m Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma. diagnostic usage,unassigned 1,0 1.2.1.59 Eye Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33058314&form=6&db=m Chlamydia trachomatis glyceraldehyde 3-phosphate dehydrogenase: Enzyme kinetics, high-resolution crystal structure, and plasminogen binding. causal interaction,ongoing research,therapeutic application,unassigned 1,1,1,0 1.2.1.59 Fallopian Tube Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18708368&form=6&db=m The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,4,0 1.2.1.59 Fascioliasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30706165&form=6&db=m Identification and characterization of glyceraldehyde 3-phosphate dehydrogenase from Fasciola gigantica. therapeutic application,unassigned 4,0 1.2.1.59 Fatty Liver http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20814553&form=6&db=m Rat strain differences in susceptibility to alcohol-induced chronic liver injury and hepatic insulin resistance. unassigned - 1.2.1.59 Fatty Liver http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21426453&form=6&db=m Peroxisome proliferator-activated receptor agonist treatment of alcohol-induced hepatic insulin resistance. unassigned - 1.2.1.59 Fatty Liver http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Fetal Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12716756&form=6&db=m Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos. causal interaction,unassigned 4,0 1.2.1.59 Fetal Growth Retardation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18684503&form=6&db=m GAPDH, 18S rRNA and YWHAZ are suitable endogenous reference genes for relative gene expression studies in placental tissues from human idiopathic fetal growth restriction. ongoing research,unassigned 2,0 1.2.1.59 Fibroma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8893764&form=6&db=m Regulation of proliferation and platelet-derived growth factor expression in palmar fibromatosis (Dupuytren contracture) by mechanical strain. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Fibrosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33497388&form=6&db=m The characterization of exosomes from fibrosarcoma cell and the useful usage of Dynamic Light Scattering (DLS) for their evaluation. ongoing research,unassigned 2,0 1.2.1.59 Filariasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26320419&form=6&db=m DNA vaccine encoding the moonlighting protein Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH) leads to partial protection in a mouse model of human filariasis. causal interaction,ongoing research,therapeutic application,unassigned 3,3,4,0 1.2.1.59 Foot Rot http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23722658&form=6&db=m Reference gene selection for quantitative PCR studies in sheep neutrophils. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Friedreich Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9779656&form=6&db=m Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 1.2.1.59 Ganglioneuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2121331&form=6&db=m Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues. causal interaction,diagnostic usage,unassigned 3,4,0 1.2.1.59 Ganglioneuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12576454&form=6&db=m Real-time analysis of tyrosine hydroxylase gene expression: a sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma. diagnostic usage,ongoing research,therapeutic application,unassigned 4,2,1,0 1.2.1.59 Ganglioneuroma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12576454&form=6&db=m Real-time analysis of tyrosine hydroxylase gene expression: a sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma. diagnostic usage,ongoing research,therapeutic application,unassigned 4,2,1,0 1.2.1.59 Gastric Fistula http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8568687&form=6&db=m Expression of immediate early genes in rat gastric myenteric neurones: a physiological response to feeding. unassigned - 1.2.1.59 Gastritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30425814&form=6&db=m Comparative study of gastric cancer and chronic gastritis via network analysis. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Gastroschisis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9126188&form=6&db=m Enterocytic gene expression is altered in experimental gastroschisis. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,2,0 1.2.1.59 Glaucoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15486605&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15138583&form=6&db=m Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17597534&form=6&db=m GAPDH is not regulated in human glioblastoma under hypoxic conditions. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,2 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19144146&form=6&db=m Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,4 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20022592&form=6&db=m A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. ongoing research,unassigned 4,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24352760&form=6&db=m Expression of insulin-like growth factor binding protein-2 (IGFBP-2) gene in negative and positive human cytomegalovirus glioblastoma multiforme tissues. ongoing research,unassigned 1,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25862007&form=6&db=m Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26713364&form=6&db=m Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH. causal interaction,ongoing research,therapeutic application,unassigned 4,3,3,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28165521&form=6&db=m High-selectivity cytology via lab-on-a-disc western blotting of individual cells. ongoing research,unassigned 2,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28780604&form=6&db=m MiR-338-5p Promotes Glioma Cell Invasion by Regulating TSHZ3 and MMP2. causal interaction,ongoing research,unassigned 1,1,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30025493&form=6&db=m Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. ongoing research,unassigned 1,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30259794&form=6&db=m ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR. diagnostic usage,ongoing research,unassigned 2,2,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33546324&form=6&db=m Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress. causal interaction,ongoing research,therapeutic application,unassigned 2,3,3,0 1.2.1.59 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33996900&form=6&db=m Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and Neuroblastoma Cells. unassigned - 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11876468&form=6&db=m Quantitative reverse transcription-PCR measurement of tissue factor mRNA in glioma. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15138583&form=6&db=m Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17196947&form=6&db=m Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22614725&form=6&db=m On the Relevance of Glycolysis Process on Brain Gliomas. causal interaction,unassigned 1,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25862007&form=6&db=m Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26032618&form=6&db=m Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26563451&form=6&db=m Hydrogen Peroxide-Induced Oxidative Stress Activates Proteasomal Trypsin-Like Activity in Human U373 Glioma Cells. ongoing research,unassigned 4,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26713364&form=6&db=m Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH. causal interaction,ongoing research,therapeutic application,unassigned 4,3,3,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28780604&form=6&db=m MiR-338-5p Promotes Glioma Cell Invasion by Regulating TSHZ3 and MMP2. causal interaction,ongoing research,unassigned 1,1,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30200472&form=6&db=m HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell. ongoing research,unassigned 2,0 1.2.1.59 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30259794&form=6&db=m ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR. diagnostic usage,ongoing research,unassigned 2,2,0 1.2.1.59 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8712219&form=6&db=m Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23302723&form=6&db=m Bacterial infection-related glomerulonephritis in adults. causal interaction,unassigned 1,0 1.2.1.59 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31496514&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase of Mycoplasma pneumoniae induces infection-related glomerulonephritis?. diagnostic usage,unassigned 1,0 1.2.1.59 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32019767&form=6&db=m CLCN5 5'UTR isoforms in human kidneys: differential expression analysis between controls and patients with glomerulonephritis. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Glomerulonephritis, IGA http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8712219&form=6&db=m Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 Glomerulonephritis, Membranous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8712219&form=6&db=m Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 Glomerulonephritis, Membranous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15954921&form=6&db=m Th2 cytokines increase and stimulate B cells to produce IgG4 in idiopathic membranous nephropathy. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Glomerulosclerosis, Focal Segmental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8712219&form=6&db=m Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (nad(p)+) (phosphorylating) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1244916&form=6&db=m Study of a kindred with hereditary spherocytosis and glyceraldehyde-3-phosphate dehydrogenase deficiency. causal interaction,unassigned 2,0 1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (nad(p)+) (phosphorylating) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6460465&form=6&db=m A simple screening procedure for glucose phosphate isomerase, phosphofructokinase, aldolase and glyceraldehyde-3-phosphate dehydrogenase deficiencies. diagnostic usage,unassigned 1,0 1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (nad(p)+) (phosphorylating) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25603270&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase is required for efficient repair of cytotoxic DNA lesions in Escherichia coli. causal interaction,unassigned 4,0 1.2.1.59 glycogen phosphorylase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6449564&form=6&db=m Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease). causal interaction,ongoing research,unassigned 4,1,0 1.2.1.59 Glycogen Storage Disease Type V http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6449564&form=6&db=m Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease). causal interaction,ongoing research,unassigned 4,1,0 1.2.1.59 Glycosuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27655796&form=6&db=m Thyroid hormone treatment decreases hepatic glucose production and renal reabsorption of glucose in alloxan-induced diabetic Wistar rats. ongoing research,unassigned 1,0 1.2.1.59 Goiter http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24900955&form=6&db=m Validation of reference genes for normalization gene expression in reverse transcription quantitative PCR in human normal thyroid and goiter tissue. ongoing research,unassigned 1,0 1.2.1.59 Goiter, Nodular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33035689&form=6&db=m Diagnostic value of circulating cell-free mtDNA in patients with suspected thyroid cancer: ND4/ND1 ratio as a new potential plasma marker. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Granuloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31669534&form=6&db=m Effects of regulatory T cells on glyceraldehyde-3-phosphate dehydrogenase vaccine efficacy against Schistosoma japonicum. causal interaction,unassigned 4,0 1.2.1.59 Granulomatous Disease, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7929187&form=6&db=m S-thiolation of glyceraldehyde-3-phosphate dehydrogenase induced by the phagocytosis-associated respiratory burst in blood monocytes. ongoing research,unassigned 1,0 1.2.1.59 Hearing Loss, Noise-Induced http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32331439&form=6&db=m Associations of Genetic Variation in Glyceraldehyde 3-Phosphate Dehydrogenase Gene with Noise-Induced Hearing Loss in a Chinese Population: A Case-Control Study. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 1.2.1.59 Heart Arrest http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18505597&form=6&db=m Selection of reference genes for quantitative real-time PCR in a rat asphyxial cardiac arrest model. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,2,0 1.2.1.59 Heart Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23527007&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Heart Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26279122&form=6&db=m GAPDH-silence preserves H9C2 cells from acute hypoxia and reoxygenation injury. causal interaction,therapeutic application,unassigned 1,4,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8603506&form=6&db=m Reduced gene expression of vascular endothelial NO synthase and cyclooxygenase-1 in heart failure. causal interaction,diagnostic usage,therapeutic application,unassigned 3,2,1,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9302352&form=6&db=m Angiotensin receptor type 1 mRNA in human right ventricular endomyocardial biopsies: downregulation in heart failure. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10630620&form=6&db=m Reduced activity of enzymes coupling ATP-generating with ATP-consuming processes in the failing myocardium. causal interaction,unassigned 1,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11008069&form=6&db=m Expression of proinflammatory cytokines in the failing human heart: comparison of recent-onset and end-stage congestive heart failure. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,1,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18922030&form=6&db=m Proteomic analysis of left ventricular remodeling in an experimental model of heart failure. ongoing research,unassigned 1,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20331858&form=6&db=m Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies. ongoing research,unassigned 4,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23527007&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28390990&form=6&db=m Selection of reference genes for gene expression studies in heart failure for left and right ventricles. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29036603&form=6&db=m Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart. ongoing research,unassigned 4,0 1.2.1.59 Hemochromatosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14563638&form=6&db=m Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10814569&form=6&db=m Specific interaction between the hepatitis delta virus RNA and glyceraldehyde 3-phosphate dehydrogenase: an enhancement on ribozyme catalysis. ongoing research,therapeutic application,unassigned 3,2,0 1.2.1.59 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15191658&form=6&db=m [Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference] causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19464723&form=6&db=m The hepatitis delta virus RNA genome interacts with eEF1A1, p54(nrb), hnRNP-L, GAPDH and ASF/SF2. therapeutic application,unassigned 1,0 1.2.1.59 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22964488&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,4,0 1.2.1.59 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24337968&form=6&db=m Redox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitis. causal interaction,ongoing research,unassigned 1,2,0 1.2.1.59 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29915506&form=6&db=m Evaluation of hepatocyte-derived microRNA-122 for diagnosis of acute and chronic hepatitis of dogs. causal interaction,diagnostic usage,unassigned 4,4,0 1.2.1.59 Hepatitis A http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8662893&form=6&db=m Specific interaction of glyceraldehyde 3-phosphate dehydrogenase with the 5'-nontranslated RNA of hepatitis A virus. causal interaction,therapeutic application,unassigned 1,2,0 1.2.1.59 Hepatitis A http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10864658&form=6&db=m Functional significance of the interaction of hepatitis A virus RNA with glyceraldehyde 3-phosphate dehydrogenase (GAPDH): opposing effects of GAPDH and polypyrimidine tract binding protein on internal ribosome entry site function. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Hepatitis A http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12560573&form=6&db=m Interaction of glyceraldehyde-3-phosphate dehydrogenase with secondary and tertiary RNA structural elements of the hepatitis A virus 3' translated and non-translated regions. unassigned - 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1366913&form=6&db=m A yeast system for stable expression of hepatitis B surface antigen. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1937046&form=6&db=m Production of hepatitis B virion-like particles in yeast. ongoing research,unassigned 2,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9680129&form=6&db=m Phosphorylation of the hepatitis B virus core protein by glyceraldehyde-3-phosphate dehydrogenase protein kinase activity. unassigned - 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9705254&form=6&db=m Identification of glyceraldehyde-3-phosphate dehydrogenase as a cellular protein that binds to the hepatitis B virus posttranscriptional regulatory element. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,1,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11882413&form=6&db=m High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12802503&form=6&db=m Evaluation of Aspergillus niger as host for virus-like particle production, using the hepatitis B surface antigen as a model. ongoing research,therapeutic application,unassigned 1,1,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15639938&form=6&db=m [Optimization of cDNA microarray fabrication] diagnostic usage,unassigned 1,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17136304&form=6&db=m Expression of hepatitis B surface antigen in Saccharomyces cerevisiae utilizing glyceraldeyhyde-3-phosphate dehydrogenase promoter of Pichia pastoris. ongoing research,unassigned 2,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18584754&form=6&db=m Controlled fed-batch fermentation of recombinant Saccharomyces cerevisiae to produce hepatitis B surface antigen. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19225715&form=6&db=m Role of glyceraldehyde-3-phosphate dehydrogenase binding to hepatitis B virus posttranscriptional regulatory element in regulating expression of HBV surface antigen. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26136865&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33251461&form=6&db=m PCR Multiplexing Based on a Single Fluorescent Channel Using Dynamic Melting Curve Analysis. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=100103566&form=6&db=m Expression of hepatitis B surface antigen in Saccharomyces cerevisiae utilizing glyceraldeyhyde-3-phosphate dehydrogenase promoter of Pichia pastoris ongoing research,unassigned 2,0 1.2.1.59 Hepatitis B, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Hepatitis C http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10567641&form=6&db=m Human hepatic glyceraldehyde-3-phosphate dehydrogenase binds to the poly(U) tract of the 3' non-coding region of hepatitis C virus genomic RNA. ongoing research,unassigned 2,0 1.2.1.59 Hepatitis C http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28548037&form=6&db=m Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 1.2.1.59 Hepatitis C http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33890542&form=6&db=m HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons. unassigned - 1.2.1.59 Hepatitis C, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Hepatitis, Alcoholic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21913943&form=6&db=m Housekeeping gene variability in the liver of alcoholic patients. causal interaction,diagnostic usage,unassigned 3,3,0 1.2.1.59 Hepatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11282488&form=6&db=m Simple quantitative assay of alpha-fetoprotein mRNA in liver tissue using the real-time detection polymerase chain reaction assay - its application for clinical use. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Hepatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11882413&form=6&db=m High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Hepatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Hepatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29915506&form=6&db=m Evaluation of hepatocyte-derived microRNA-122 for diagnosis of acute and chronic hepatitis of dogs. causal interaction,diagnostic usage,unassigned 4,4,0 1.2.1.59 Hernias, Diaphragmatic, Congenital http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16626602&form=6&db=m Circulating cell-free fetal messenger RNA levels after fetoscopic interventions of complicated pregnancies. causal interaction,diagnostic usage,unassigned 4,4,0 1.2.1.59 Hodgkin Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1774960&form=6&db=m Expression of housekeeping genes in Hodgkin's disease lymph nodes. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9702787&form=6&db=m Neuronal death in cultured murine cortical cells is induced by inhibition of GAPDH and triosephosphate isomerase. causal interaction,unassigned 2,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9778585&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts. causal interaction,unassigned 2,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9779656&form=6&db=m Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11208907&form=6&db=m Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12008025&form=6&db=m Alteration of nuclear glyceraldehyde-3-phosphate dehydrogenase structure in Huntington's disease fibroblasts. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,1,1 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12428732&form=6&db=m Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders? causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12691731&form=6&db=m Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington's disease. ongoing research,unassigned 1,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15486605&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23819039&form=6&db=m Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis. causal interaction,ongoing research,unassigned 2,1,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25625921&form=6&db=m GAPDH binders as potential drugs for the therapy of polyglutamine diseases: Design of a new screening assay. causal interaction,unassigned 2,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26268247&form=6&db=m Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. unassigned - 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26662373&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase augments the intercellular transmission and toxicity of polyglutamine aggregates in a cell model of Huntington disease. ongoing research,unassigned 2,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30254002&form=6&db=m Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34369082&form=6&db=m DNM3OS regulates GAPDH expression and influences the molecular pathogenesis of Huntington's disease. unassigned - 1.2.1.59 Hypercholesterolemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22273152&form=6&db=m Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats. unassigned - 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7968588&form=6&db=m Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice. causal interaction,ongoing research,unassigned 1,3,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11050244&form=6&db=m Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. diagnostic usage,unassigned 3,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15111614&form=6&db=m Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells. causal interaction,unassigned 2,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16619259&form=6&db=m Chronic hyperglycemia modulates osteoblast gene expression through osmotic and non-osmotic pathways. causal interaction,ongoing research,unassigned 2,1,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17184177&form=6&db=m Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its complications. causal interaction,ongoing research,unassigned 4,1,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18852331&form=6&db=m Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy. causal interaction,unassigned 4,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19875652&form=6&db=m Glyceraldehyde 3 phosphate dehydrogenase in retinal microvasculature: Implications for the development and progression of diabetic retinopathy. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22124463&form=6&db=m Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin. causal interaction,unassigned 4,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22493144&form=6&db=m Tissue-specific selection of stable reference genes for real-time PCR normalization in an obese rat model. ongoing research,unassigned 1,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22940604&form=6&db=m Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1. causal interaction,unassigned 1,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25176140&form=6&db=m High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25450812&form=6&db=m Type 2 diabetes mellitus: Role of melatonin and oxidative stress. unassigned - 1.2.1.59 Hyperglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27650728&form=6&db=m Easy-to-use strategy for reference gene selection in quantitative real-time PCR experiments. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14672171&form=6&db=m The housekeeping genes GAPDH and cyclophilin are regulated by metabolic state in the liver of dairy cows. causal interaction,unassigned 4,0 1.2.1.59 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34149169&form=6&db=m Immunomodulatory effect of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in allergic conditions in vitro and in vivo. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,1,0 1.2.1.59 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8722442&form=6&db=m Influence of pressure overload and ACE inhibitor therapy on constitutive protein mRNA expression in the spontaneously hypertensive rat. causal interaction,therapeutic application,unassigned 2,4,0 1.2.1.59 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29171745&form=6&db=m Retracted: Resveratrol inhibits oesophageal adenocarcinoma cell proliferation via AMP-activated protein kinase signaling ongoing research,unassigned 2,0 1.2.1.59 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31518162&form=6&db=m Dietary capsaicin-mediated attenuation of hypertension in a rat model of renovascular hypertension. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Hypertension, Pulmonary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23801767&form=6&db=m GAPDH is critical for superior efficacy of female bone marrow-derived mesenchymal stem cells on pulmonary hypertension. unassigned - 1.2.1.59 Hypotension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8521087&form=6&db=m [Does nitric oxide stress exist?] causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Infarction, Middle Cerebral Artery http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11891433&form=6&db=m Induction of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression in rat brain after focal ischemia/reperfusion. causal interaction,ongoing research,unassigned 1,3,0 1.2.1.59 Infarction, Middle Cerebral Artery http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16721606&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase versus toluidine blue as a marker for infarct volume estimation following permanent middle cerebral artery occlusion in mice. diagnostic usage,therapeutic application,unassigned 2,2,0 1.2.1.59 Infarction, Middle Cerebral Artery http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29938598&form=6&db=m Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke. unassigned - 1.2.1.59 Infarction, Middle Cerebral Artery http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32722981&form=6&db=m BNIP3L/NIX degradation leads to mitophagy deficiency in ischemic brains. unassigned - 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=664114&form=6&db=m Effect of acute infectious disease on human isometric muscle endurance. causal interaction,unassigned 3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2173551&form=6&db=m Effects of a diabetogenic strain of encephalomyocarditis (EMC) virus on protein synthesis in mouse islets of Langerhans. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8411369&form=6&db=m Differential effects of rabies and borna disease viruses on immediate-early- and late-response gene expression in brain tissues. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8639754&form=6&db=m Accumulation of cytosolic glyceraldehyde-3-phosphate dehydrogenase RNA under biological stress conditions and elicitor treatments in potato. unassigned - 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9820153&form=6&db=m Translational control of viral and host protein synthesis during the course of herpes simplex virus type 1 infection: evidence that initiation of translation is the limiting step. causal interaction,diagnostic usage,unassigned 2,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10219595&form=6&db=m Clinical strains of Candida albicans express the surface antigen glyceraldehyde 3-phosphate dehydrogenase in vitro and in infected tissues. causal interaction,ongoing research,unassigned 1,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10531467&form=6&db=m Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10708446&form=6&db=m The lymphocytic choriomeningitis virus RING protein Z associates with eukaryotic initiation factor 4E and selectively represses translation in a RING-dependent manner. ongoing research,unassigned 3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11595231&form=6&db=m Immunisation with Salmonella typhimurium-delivered glyceraldehyde-3-phosphate dehydrogenase protects mice against challenge infection with Echinococcus multilocularis eggs. ongoing research,therapeutic application,unassigned 1,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11960638&form=6&db=m Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14529956&form=6&db=m Quantitative detection for low levels of Helicobacter pylori infection in experimentally infected mice by real-time PCR. diagnostic usage,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15081603&form=6&db=m Real time PCR for monitoring regulation of host gene expression in herpes simplex virus type 1-infected human diploid cells. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15331749&form=6&db=m Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores. causal interaction,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15780579&form=6&db=m Mucosal immunisation with novel Streptococcus pneumoniae protein antigens enhances bacterial clearance in an acute mouse lung infection model. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16034203&form=6&db=m Vaccine efficacy of recombinant GAPDH of Edwardsiella tarda against Edwardsiellosis. causal interaction,therapeutic application,unassigned 1,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16159698&form=6&db=m Evaluation of the suitability of six host genes as internal control in real-time RT-PCR assays in chicken embryo cell cultures infected with infectious bursal disease virus. ongoing research,unassigned 2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16368993&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase of Paracoccidioides brasiliensis is a cell surface protein involved in fungal adhesion to extracellular matrix proteins and interaction with cells. causal interaction,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16779630&form=6&db=m Evaluation of the usefulness of anti-glyceraldehyde-3-phosphate dehydrogenase antibodies as a treatment for invasive candidiasis in a murine model. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17449317&form=6&db=m Role of secreted glyceraldehyde-3-phosphate dehydrogenase in the infection mechanism of enterohemorrhagic and enteropathogenic Escherichia coli: interaction of the extracellular enzyme with human plasminogen and fibrinogen. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17629116&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda has protective antigenicity against Vibrio anguillarum in Japanese flounder. causal interaction,therapeutic application,unassigned 2,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18448541&form=6&db=m Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19368702&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3' ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein. causal interaction,therapeutic application,unassigned 2,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21246232&form=6&db=m Surface Display of Aeromonas hydrophila GAPDH in Attenuated Vibrio anguillarum to Develop a Noval Multivalent Vector Vaccine. unassigned - 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21637421&form=6&db=m Evaluation of reference genes for real-time PCR studies of Brazilian Somalis sheep infected by gastrointestinal nematodes. ongoing research,unassigned 2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21925148&form=6&db=m Systematic selection of housekeeping genes for gene expression normalization in chicken embryo fibroblasts infected with Newcastle disease virus. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,2,1 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22017642&form=6&db=m Secreted glyceraldehyde-3-phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture. therapeutic application,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22114550&form=6&db=m Inhibition of IL-10 production by maternal antibodies against Group B Streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment. causal interaction,ongoing research,therapeutic application,unassigned 4,1,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22395020&form=6&db=m Validation of reference genes for expression analysis in the salivary gland and the intestine of Rhodnius prolixus (Hemiptera, Reduviidae) under different experimental conditions by quantitative real-time PCR. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22492233&form=6&db=m Changes in the contents of metabolites and enzyme activities in rice plants responding to Rhizoctonia solani Kuhn infection: activation of glycolysis and connection to phenylpropanoid pathway. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22985345&form=6&db=m VACCINE-INDUCED PROTECTION AGAINST MURINE SCHISTOSOMIASIS MANSONI WITH LARVAL EXCRETORY-SECRETORY ANTIGENS AND PAPAIN OR TYPE-2 CYTOKINES. therapeutic application,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23000128&form=6&db=m Construction and immune effect of Haemophilus parasuis DNA vaccine encoding glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in mice. ongoing research,therapeutic application,unassigned 3,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23125352&form=6&db=m Role of cytosolic glyceraldehyde-3-phosphate dehydrogenase in visceral organ infection by Leishmania donovani. causal interaction,ongoing research,unassigned 1,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23237566&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase negatively regulates human immunodeficiency virus type 1 infection. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,4,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23332158&form=6&db=m NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-?B activation. therapeutic application,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23507306&form=6&db=m Cloning and heterologous overexpression of three gap genes encoding different glyceraldehyde-3-phosphate dehydrogenases from the plant pathogenic bacterium Pseudomonas syringae pv. tomato strain DC3000. causal interaction,unassigned 3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23568215&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase, an immunogenic Streptococcus equi ssp. zooepidemicus adhesion protein and protective antigen. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23579085&form=6&db=m An improved infectivity assay combining cell culture with real-time PCR for rapid quantification of human adenoviruses 41 and semi-quantification of human adenovirus in sewage. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23954326&form=6&db=m Selection of reference genes for gene expression studies in virus-infected monocots using quantitative real-time PCR. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24128375&form=6&db=m Proteome profiling of the dimorphic fungus Penicillium marneffei extracellular proteins and identification of glyceraldehyde-3-phosphate dehydrogenase as an important adhesion factor for conidial attachment. causal interaction,therapeutic application,unassigned 2,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24492602&form=6&db=m Immunoprotection of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Lactococcus garvieae against Lactococcosis in tilapia. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25852696&form=6&db=m Induction of Protective Immune Responses Against Schistosomiasis haematobium in Hamsters and Mice Using Cysteine Peptidase-Based Vaccine. therapeutic application,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26092250&form=6&db=m Dengue virus NS1 protein interacts with the ribosomal protein RPL18: this interaction is required for viral translation and replication in Huh-7 cells. diagnostic usage,ongoing research,unassigned 1,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26094646&form=6&db=m Relative expression analysis of IL-5 and IL-6 genes in tropical sheep breed Pelibuey infected with Haemonchus contortus. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26136865&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26238194&form=6&db=m Identification and selection of normalization controls for quantitative transcript analysis in Blumeria graminis. ongoing research,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26378175&form=6&db=m Dengue Virus NS1 Protein Modulates Cellular Energy Metabolism by Increasing Glyceraldehyde-3-Phosphate Dehydrogenase Activity. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26497487&form=6&db=m Assessment of reference gene stability in Rice stripe virus and Rice black streaked dwarf virus infection rice by quantitative Real-time PCR. diagnostic usage,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26673420&form=6&db=m A Safe and Stable Neonatal Vaccine Targeting GAPDH Confers Protection against Group B Streptococcus Infections in Adult Susceptible Mice. therapeutic application,unassigned 2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26886224&form=6&db=m A Panel of Stably Expressed Reference Genes for Real-Time qPCR Gene Expression Studies of Mallards (Anas platyrhynchos). diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27001537&form=6&db=m Excreted cytoplasmic proteins contribute to pathogenicity in Staphylococcus aureus. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,3,2,1 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27332725&form=6&db=m InterFeriNg with Acet?lation: Stress-Levels of Acetate Improve Memory T Cell Function. causal interaction,unassigned 3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27387501&form=6&db=m Citrobacter rodentium NleB Protein Inhibits Tumor Necrosis Factor (TNF) Receptor-associated Factor 3 (TRAF3) Ubiquitination to Reduce Host Type I Interferon Production. therapeutic application,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27448823&form=6&db=m Evaluation and validation of reference gene stability during Marek's disease virus (MDV) infection. causal interaction,unassigned 3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28301553&form=6&db=m Multiplex PCR as a tool for the diagnosis of Leishmania spp. kDNA and the gapdh housekeeping gene of mammal hosts. therapeutic application,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28346516&form=6&db=m Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase. ongoing research,therapeutic application,unassigned 2,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28548037&form=6&db=m Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28655566&form=6&db=m Determination of suitable reference genes for RT-qPCR analysis of murine Cytomegalovirus in vivo and in vitro. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28689086&form=6&db=m Validation of reference genes for quantifying changes in gene expression in virus-infected tobacco. diagnostic usage,therapeutic application,unassigned 2,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29847601&form=6&db=m Identification of immunogenic proteins and evaluation of recombinant PDHA1 and GAPDH as potential vaccine candidates against Streptococcus iniae infection in flounder (Paralichthys olivaceus). therapeutic application,unassigned 3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30456380&form=6&db=m Identification of Plasmodium GAPDH epitopes for generation of antibodies that inhibit malaria infection. causal interaction,ongoing research,therapeutic application,unassigned 1,1,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30640524&form=6&db=m Trafficking of a multifunctional protein by endosomal micro-autophagy: linking two independent unconventional secretory pathways. unassigned - 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30766520&form=6&db=m ?-Actin: Not a Suitable Internal Control of Hepatic Fibrosis Caused by Schistosoma japonicum. causal interaction,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31168702&form=6&db=m Anti-CTLA-4 monoclonal antibody improves efficacy of the glyceraldehyde-3-phosphate dehydrogenase protein vaccine against Schistosoma japonicum in mice. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31773146&form=6&db=m Selection and Validation of Suitable Reference Genes for RT-qPCR Analysis in Apolygus lucorum (Hemiptera: Miridae). diagnostic usage,ongoing research,therapeutic application,unassigned 2,2,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32442683&form=6&db=m Hypoxia promotes Chlamydia trachomatis L2/434/Bu growth in immortal human epithelial cells via activation of the PI3K-AKT pathway and maintenance of a balanced NAD+/NADH ratio. ongoing research,unassigned 2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32444639&form=6&db=m Identification of Reference Genes in Chicken Intraepithelial Lymphocyte Natural Killer Cells Infected with Very-virulent Infectious Bursal Disease Virus. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33275816&form=6&db=m Validation of superior reference genes for qRT-PCR and Western blot analyses in marine Emiliania huxleyi-virus model system. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33430251&form=6&db=m Different Modulatory Effects of Four Methicillin-Resistant Staphylococcus aureus Clones on MG-63 Osteoblast-Like Cells. causal interaction,ongoing research,unassigned 1,3,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33459133&form=6&db=m Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy. ongoing research,unassigned 2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33597592&form=6&db=m Development and validation of a multiplex qPCR assay for detection and relative quantification of HPV16 and HPV18 E6 and E7 oncogenes. causal interaction,diagnostic usage,unassigned 3,4,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33857623&form=6&db=m Development of species-specific IgM antibodies and elevation of mucosal immune response in Labeo rohita using recombinant bicistronic nano DNA vaccine priming. therapeutic application,unassigned 1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33890146&form=6&db=m Cytoskeletal Alteration Is an Early Cellular Response in Pulmonary Epithelium Infected with Aspergillus fumigatus Rather than Scedosporium apiospermum. unassigned - 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34160254&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity. causal interaction,ongoing research,therapeutic application,unassigned 4,2,2,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34313529&form=6&db=m Rice black-streaked dwarf virus P10 promotes phosphorylation of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) to induce autophagy in Laodelphax striatellus. causal interaction,therapeutic application,unassigned 2,1,0 1.2.1.59 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34534548&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression. unassigned - 1.2.1.59 Infertility http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11225901&form=6&db=m Approaches to post-testicular contraception. causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Infertility http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19675149&form=6&db=m Plastidial glyceraldehyde-3-phosphate dehydrogenase deficiency leads to altered root development and affects the sugar and amino Acid balance in Arabidopsis. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Infertility http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26846113&form=6&db=m Anti-GAPDHS antibodies: a biomarker of immune infertility. unassigned - 1.2.1.59 Infertility, Male http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20107025&form=6&db=m The plastidial glyceraldehyde-3-phosphate dehydrogenase is critical for viable pollen development in Arabidopsis. unassigned - 1.2.1.59 Infertility, Male http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20409345&form=6&db=m Genome-wide profiling of gene expression in the epididymis of alpha-chlorohydrin-induced infertile rats using an oligonucleotide microarray. therapeutic application,unassigned 1,0 1.2.1.59 Inflammatory Bowel Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9895376&form=6&db=m 5-aminosalicylic acid prevents oxidant mediated damage of glyceraldehyde-3-phosphate dehydrogenase in colon epithelial cells. causal interaction,unassigned 3,0 1.2.1.59 Inflammatory Bowel Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30917710&form=6&db=m The Effect of IL-26 on TNF-?-Induced CXCL8 Responses by Colonic Epithelial Cell Lines. unassigned - 1.2.1.59 Inflammatory Bowel Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32424999&form=6&db=m Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,2 1.2.1.59 Inflammatory Bowel Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32525764&form=6&db=m Elucidation of colon-protective efficacy of diosgenin in experimental TNBS-induced colitis: inhibition of NF-?B/IkB-? and Bax/Caspase-1 signaling pathways. unassigned - 1.2.1.59 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18291599&form=6&db=m On the mechanism of phenotypic conversion of human cervical adenocarcinoma HeLa cells surviving infection by influenza B virus: Potential implications for biological management of adenocarcinomas. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18598722&form=6&db=m Typing (A/B) and subtyping (H1/H3/H5) of influenza A viruses by multiplex real-time RT-PCR assays. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23043930&form=6&db=m 18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells. ongoing research,unassigned 3,0 1.2.1.59 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34133917&form=6&db=m Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 1.2.1.59 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16128592&form=6&db=m Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance. causal interaction,ongoing research,unassigned 1,1,0 1.2.1.59 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17115034&form=6&db=m Forward chemical genetic approach identifies new role for GAPDH in insulin signaling. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31231489&form=6&db=m Expression of the receptor of advanced glycation end-products (RAGE) and membranal location in peripheral blood mononuclear cells (PBMC) in obesity and insulin resistance. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33256145&form=6&db=m Redox-Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy. causal interaction,diagnostic usage,therapeutic application,unassigned 2,1,1,0 1.2.1.59 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34466413&form=6&db=m Association Between First Episode Schizophrenia, Metabolic Syndrome and Insulin Resistance-Related Proteins in Female Balb/C Mice. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15668518&form=6&db=m A New 5' Terminal Murine GAPDH Exon Identified Using 5'RACE LaNe. diagnostic usage,unassigned 3,0 1.2.1.59 Intestinal Volvulus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15955451&form=6&db=m Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH). therapeutic application,unassigned 1,0 1.2.1.59 Intestinal Volvulus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26320419&form=6&db=m DNA vaccine encoding the moonlighting protein Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH) leads to partial protection in a mouse model of human filariasis. causal interaction,ongoing research,therapeutic application,unassigned 3,3,4,0 1.2.1.59 Iron Deficiencies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7867783&form=6&db=m The effect of iron status on glyceraldehyde 3-phosphate dehydrogenase expression in rat liver. unassigned - 1.2.1.59 Ischemic Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29938598&form=6&db=m Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke. unassigned - 1.2.1.59 Keratoconus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16015083&form=6&db=m Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patients. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Kidney Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21634111&form=6&db=m [Novel reference gene RPN1 for normalization of quantitative data in lung and kidney cancer]. diagnostic usage,ongoing research,unassigned 2,1,0 1.2.1.59 Kidney Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Kidney Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24450150&form=6&db=m [Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans]. diagnostic usage,unassigned 3,0 1.2.1.59 Laryngeal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28225552&form=6&db=m Potential clinical significance of perioperative levels of mRNA in plasma from patients with cancer of the larynx or hypopharynx. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Leiomyoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12904697&form=6&db=m mRNA-expression of often used house-keeping genes and the relation between RNA and DNA are sex steroid-dependent parameters in human myometrium and fibroids. causal interaction,ongoing research,unassigned 1,2,0 1.2.1.59 Leiomyoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24423317&form=6&db=m Expression of a mitochondrial progesterone receptor (PR-M) in leiomyomata and association with increased mitochondrial membrane potential. diagnostic usage,unassigned 2,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8834064&form=6&db=m Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs. ongoing research,unassigned 2,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9749576&form=6&db=m Structure/function in neuroprotection and apoptosis. causal interaction,unassigned 1,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15748441&form=6&db=m [RT-PCR detecting NUP98-HOX fusion gene in leukemia] diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15854547&form=6&db=m [Significance of dynamic detection of WT1 expression on monitoring minimal residual disease in leukemia patients following allogeneic bone marrow transplantation] diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15860112&form=6&db=m Characterization of an immortalized oviduct cell line from the cynomolgus monkey (Macaca fascicularis). causal interaction,diagnostic usage,unassigned 3,3,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16920200&form=6&db=m Urea-nuclease treatment of concentrated retrovirions preserves viral RNA and removes polymerase chain reaction-amplifiable cellular RNA and DNA. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20119960&form=6&db=m Digital quantification of gene expression using emulsion PCR. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23155364&form=6&db=m Quantification of BCR-ABL mRNA in plasma/serum of patients with chronic myelogenous leukemia. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,4,0 1.2.1.59 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29490943&form=6&db=m Loss of Pax5 exploits Sca1-BCR-ABLp190 susceptibility to confer the metabolic shift essential for pB-ALL. unassigned - 1.2.1.59 Leukemia, Myelogenous, Chronic, BCR-ABL Positive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19747091&form=6&db=m Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,4,0 1.2.1.59 Leukemia, Myelogenous, Chronic, BCR-ABL Positive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23150808&form=6&db=m Gene Expression upon Proliferation and Differentiation of Hematopoietic Cells with Ph Chromosome ex vivo. ongoing research,unassigned 3,0 1.2.1.59 Leukemia, Myelogenous, Chronic, BCR-ABL Positive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23155364&form=6&db=m Quantification of BCR-ABL mRNA in plasma/serum of patients with chronic myelogenous leukemia. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,4,0 1.2.1.59 Leukemia, Myelogenous, Chronic, BCR-ABL Positive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30929559&form=6&db=m GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia. causal interaction,therapeutic application,unassigned 3,2,0 1.2.1.59 Listeriosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24600592&form=6&db=m Cellular vaccines in listeriosis: role of the Listeria antigen GAPDH. causal interaction,ongoing research,therapeutic application,unassigned 1,1,4,0 1.2.1.59 Listeriosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33194812&form=6&db=m Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase. unassigned - 1.2.1.59 Liver Cirrhosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9428231&form=6&db=m Down-regulation of hepatic and renal 11 beta-hydroxysteroid dehydrogenase in rats with liver cirrhosis. causal interaction,ongoing research,unassigned 1,3,0 1.2.1.59 Liver Cirrhosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11882413&form=6&db=m High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Liver Cirrhosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26136865&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 1.2.1.59 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9551681&form=6&db=m Mycobacterial DNA not detected in liver sections from patients with primary biliary cirrhosis. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11882413&form=6&db=m High serum glyceraldehyde-3-phosphate dehydrogenase levels in patients with liver cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22006949&form=6&db=m Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation. causal interaction,ongoing research,unassigned 2,1,0 1.2.1.59 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034126&form=6&db=m Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 1.2.1.59 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32597296&form=6&db=m The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB. ongoing research,unassigned 1,0 1.2.1.59 Liver Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19036168&form=6&db=m Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR. causal interaction,unassigned 1,0 1.2.1.59 Liver Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Liver Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30232003&form=6&db=m CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer. causal interaction,ongoing research,therapeutic application,unassigned 4,4,1,0 1.2.1.59 Liver Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32801756&form=6&db=m Analysis of Key Genes Regulating the Warburg Effect in Patients with Gastrointestinal Cancers and Selective Inhibition of This Metabolic Pathway in Liver Cancer Cells. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 1.2.1.59 Lung Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18671841&form=6&db=m PSMB2 and RPL32 are suitable denominators to normalize gene expression profiles in bronchoalveolar cells. ongoing research,unassigned 2,0 1.2.1.59 Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30770755&form=6&db=m Identification of differentially expressed proteins in the injured lung from zinc chloride smoke inhalation based on proteomics analysis. unassigned - 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3089988&form=6&db=m Similarity between glyceraldehyde-3-phosphate dehydrogenase and a 37,000-dalton protein which is abundantly expressed in human lung cancers. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3664468&form=6&db=m Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16319328&form=6&db=m Choice of endogenous control for gene expression in nonsmall cell lung cancer. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19800890&form=6&db=m Direct Binding of Glyceraldehyde 3-Phosphate Dehydrogenase to Telomeric DNA Protects Telomeres against Chemotherapy-Induced Rapid Degradation. causal interaction,ongoing research,therapeutic application,unassigned 4,1,4,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20142997&form=6&db=m Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20193080&form=6&db=m Simultaneous down-regulation of tumor suppressor genes RBSP3/CTDSPL, NPRL2/G21 and RASSF1A in primary non-small cell lung cancer. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20682026&form=6&db=m A sequence-based approach to identify reference genes for gene expression analysis. therapeutic application,unassigned 1,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21503779&form=6&db=m Gene expression of somatostatin receptor subtypes SSTR2a, SSTR3 and SSTR5 in peripheral blood of neuroendocrine lung cancer affected patients. diagnostic usage,ongoing research,therapeutic application,unassigned 4,4,1,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21749859&form=6&db=m Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells. causal interaction,ongoing research,unassigned 3,4,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23620736&form=6&db=m The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (GACC) genes correlates with cancer stage and poor survival in patients with solid tumors. causal interaction,diagnostic usage,unassigned 4,2,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23988223&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24450150&form=6&db=m [Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans]. diagnostic usage,unassigned 3,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27802291&form=6&db=m ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology. diagnostic usage,unassigned 1,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31232177&form=6&db=m Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPK? signaling in STK11 mutant lung cancer. ongoing research,unassigned 1,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31257027&form=6&db=m BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,1,3,1 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31448672&form=6&db=m PAQR3 suppresses the growth of non-small cell lung cancer cells via modulation of EGFR-mediated autophagy. ongoing research,unassigned 1,0 1.2.1.59 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31567534&form=6&db=m Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,2,0 1.2.1.59 Lyme Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8557349&form=6&db=m A glyceraldehyde-3-phosphate dehydrogenase homolog in Borrelia burgdorferi and Borrelia hermsii. ongoing research,unassigned 2,0 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8220138&form=6&db=m Investigation of the expression of housekeeping genes in non-Hodgkin's lymphoma. causal interaction,unassigned 1,0 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14655758&form=6&db=m Molecular characterization of BCL6 breakpoints in primary diffuse large B-cell lymphomas of the central nervous system identifies GAPD as novel translocation partner. unassigned - 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23597945&form=6&db=m Tumor hypoxia and metabolism -- towards novel anticancer approaches. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,4,0 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25394713&form=6&db=m GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-?B-dependent induction of HIF-1? causal interaction,diagnostic usage,unassigned 2,4,0 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29658582&form=6&db=m Sirt1/Nrf2 signalling pathway prevents cognitive impairment in diabetic rats through anti?oxidative stress induced by miRNA?23b?3p expression. diagnostic usage,ongoing research,unassigned 2,1,0 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31447347&form=6&db=m GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-?B-Dependent Mechanism. diagnostic usage,unassigned 3,0 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32442224&form=6&db=m Glycolytic biomarkers predict transformation in patients with follicular lymphoma. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,3,0 1.2.1.59 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33838689&form=6&db=m Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway. ongoing research,unassigned 4,0 1.2.1.59 Lymphoma, B-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29582634&form=6&db=m Characterization of Apoptosis in a Breast Cancer Cell Line after IL-10 Silencing diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Lymphoma, B-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33838689&form=6&db=m Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway. ongoing research,unassigned 4,0 1.2.1.59 Lymphoma, Non-Hodgkin http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25394713&form=6&db=m GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-?B-dependent induction of HIF-1? causal interaction,diagnostic usage,unassigned 2,4,0 1.2.1.59 Lymphoma, T-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25608858&form=6&db=m Glutathione-garlic sulfur conjugates: slow hydrogen sulfide releasing agents for therapeutic applications. ongoing research,unassigned 3,0 1.2.1.59 Lymphoma, T-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31447347&form=6&db=m GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-?B-Dependent Mechanism. diagnostic usage,unassigned 3,0 1.2.1.59 Macular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8690030&form=6&db=m Studies on the mechanism of early onset macular degeneration in cynomolgus (Macaca fascicularis) monkeys. I. Abnormal concentrations of two proteins in the retina. causal interaction,diagnostic usage,unassigned 4,2,0 1.2.1.59 Macular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8795458&form=6&db=m Studies on the mechanism of early onset macular degeneration in cynomolgus monkeys. II. Suppression of metallothionein synthesis in the retina in oxidative stress. unassigned - 1.2.1.59 Malaria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14646080&form=6&db=m Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase. causal interaction,therapeutic application,unassigned 2,4,0 1.2.1.59 Malaria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25137375&form=6&db=m Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Malaria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26761615&form=6&db=m Direct RNA detection without nucleic acid purification and PCR: Combining sandwich hybridization with signal amplification based on branched hybridization chain reaction. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Malaria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27551151&form=6&db=m Identification of GAPDH on the surface of Plasmodium sporozoites as a new candidate for targeting malaria liver invasion. causal interaction,unassigned 2,0 1.2.1.59 Malaria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28552792&form=6&db=m Plasmodium glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target. causal interaction,diagnostic usage,therapeutic application,unassigned 2,2,4,0 1.2.1.59 Malaria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30456380&form=6&db=m Identification of Plasmodium GAPDH epitopes for generation of antibodies that inhibit malaria infection. causal interaction,ongoing research,therapeutic application,unassigned 1,1,2,0 1.2.1.59 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9831264&form=6&db=m Prolactin receptor gene expression and foetal adipose tissue. ongoing research,unassigned 2,0 1.2.1.59 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14672171&form=6&db=m The housekeeping genes GAPDH and cyclophilin are regulated by metabolic state in the liver of dairy cows. causal interaction,unassigned 4,0 1.2.1.59 Marek Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27448823&form=6&db=m Evaluation and validation of reference gene stability during Marek's disease virus (MDV) infection. causal interaction,unassigned 3,0 1.2.1.59 Mastitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15066729&form=6&db=m Characterization of two proteins of Staphylococcus aureus isolated from bovine clinical mastitis with homology to glyceraldehyde-3-phosphate dehydrogenase. diagnostic usage,ongoing research,therapeutic application,unassigned 2,4,2,0 1.2.1.59 Mastitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21524534&form=6&db=m Technical note: Validation of candidate reference genes for normalization of quantitative PCR in bovine mammary epithelial cells responding to inflammatory stimuli. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10596911&form=6&db=m Sensitivity to extrinsically supplied interferon and the endogenous expression of interferon in melanoma cell lines. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11139316&form=6&db=m Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases. ongoing research,unassigned 2,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11476540&form=6&db=m Ribosomal 18S RNA prevails over glyceraldehyde-3-phosphate dehydrogenase and beta-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12538475&form=6&db=m Detecting homozygous deletions in the CDKN2A(p16(INK4a))/ARF(p14(ARF)) gene in urinary bladder cancer using real-time quantitative PCR. ongoing research,unassigned 4,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12544092&form=6&db=m Gene expression profiling of melanocytic lesions. causal interaction,unassigned 1,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18554498&form=6&db=m The normalization of gene expression data in melanoma: investigating the use of glyceraldehyde 3-phosphate dehydrogenase and 18S ribosomal RNA as internal reference genes for quantitative real-time PCR. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20051782&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase expression is altered by hypoxia in melanoma cells and primary human melanocytes. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20977885&form=6&db=m Isolation of tumorigenic circulating melanoma cells. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23026046&form=6&db=m Sperm-specific glyceraldehyde-3-phosphate dehydrogenase is expressed in melanoma cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25550585&form=6&db=m Deregulation of glyceraldehyde-3-phosphate dehydrogenase expression during tumor progression of human cutaneous melanoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,1 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28168807&form=6&db=m Hypoxia-induced HIF1? targets in melanocytes reveal a molecular profile associated with poor melanoma prognosis. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30537064&form=6&db=m Prognostic implications of markers of the metabolic phenotype in human cutaneous melanoma. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31567589&form=6&db=m Identification of robust reference genes for studies of gene expression in FFPE melanoma samples and melanoma cell lines. therapeutic application,unassigned 1,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32021677&form=6&db=m The Highlighted Role of GAPDH and Nitric-Oxide Synthase Regulator Activity in Proton Beam Irradiated Melanoma BLM Cells. causal interaction,ongoing research,unassigned 2,2,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33140730&form=6&db=m [Expression of sperm-specific glyceraldehyde-3-phosphate dehydrogenase in melanoma cells changes their energy metabolism]. causal interaction,ongoing research,unassigned 1,4,0 1.2.1.59 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34249897&form=6&db=m Sperm-Specific Glycolysis Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Regulated by Transcription Factor SOX10 to Promote Uveal Melanoma Tumorigenesis. causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Melanoma, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25397718&form=6&db=m Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Memory Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34341704&form=6&db=m Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-? Aggregation and Cytotoxicity. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Meningioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21806841&form=6&db=m Selection of suitable reference genes for quantitative real-time polymerase chain reaction in human meningiomas and arachnoidea. diagnostic usage,unassigned 1,0 1.2.1.59 Meningioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26413777&form=6&db=m VEGF-A mRNA measurement in meningiomas using a new simplified approach: branched DNA and chemiluminescence. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Meningioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29079997&form=6&db=m Validation of Reference Genes for Expression Studies in Human Meningiomas under Different Experimental Settings. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Meningitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20441576&form=6&db=m Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes. ongoing research,unassigned 1,0 1.2.1.59 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15770658&form=6&db=m New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. unassigned - 1.2.1.59 Microphthalmos http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9710594&form=6&db=m Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter. unassigned - 1.2.1.59 Microvascular Angina http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22419929&form=6&db=m Altered transcriptional activity of gene encoding GAPDH in peripheral blood mononuclear cells from patients with cardiac syndrome X - an important part in pathology of microvascular angina? ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Motor Neuron Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21044297&form=6&db=m Effects of gene therapy on muscle 18S rRNA expression in mouse model of ALS. ongoing research,unassigned 1,0 1.2.1.59 Movement Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27859598&form=6&db=m Reduction of GAPDH in lenses of Parkinson's disease patients: A possible new biomarker. causal interaction,therapeutic application,unassigned 3,2,0 1.2.1.59 Mucopolysaccharidoses http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29916295&form=6&db=m Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Multiple Myeloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31242129&form=6&db=m MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4. diagnostic usage,unassigned 1,0 1.2.1.59 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20610654&form=6&db=m Inhibition of glyceraldehyde-3-phosphate dehydrogenase activity by antibodies present in the cerebrospinal fluid of patients with multiple sclerosis. causal interaction,diagnostic usage,unassigned 1,2,0 1.2.1.59 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26395032&form=6&db=m Identification of Suitable Reference Genes for Peripheral Blood Mononuclear Cell Subset Studies in Multiple Sclerosis. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 1.2.1.59 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30208760&form=6&db=m Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1. unassigned - 1.2.1.59 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31759082&form=6&db=m Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease. therapeutic application,unassigned 1,0 1.2.1.59 Muscle Spasticity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21930674&form=6&db=m Tail muscle parvalbumin content is decreased in chronic sacral spinal cord injured rats with spasticity. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 1.2.1.59 Muscular Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21354103&form=6&db=m Proteomic analysis of muscle affected by motor neuron degeneration: The wobbler mouse model of amyotrophic lateral sclerosis. diagnostic usage,unassigned 1,0 1.2.1.59 Muscular Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Muscular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2381520&form=6&db=m Metabolic myopathy produced by acute inhibition of glyceraldehyde-3-phosphate dehydrogenase with ortho-iodosobenzoic acid. causal interaction,ongoing research,therapeutic application,unassigned 2,4,2,0 1.2.1.59 Mycoses http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25501189&form=6&db=m Selection of optimized candidate reference genes for qRT-PCR normalization in rice (Oryza sativa L.) during Magnaporthe oryzae infection and drought. unassigned - 1.2.1.59 Mycoses http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27392023&form=6&db=m Evaluation of Reference Genes for Reverse Transcription Quantitative PCR Studies of Physiological Responses in the Ghost Moth, Thitarodes armoricanus (Lepidoptera, Hepialidae). diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8974068&form=6&db=m Decreased expression of cardiac sarcoplasmic reticulum Ca(2+)-pump ATPase in congestive heart failure due to myocardial infarction. causal interaction,diagnostic usage,therapeutic application,unassigned 1,2,2,0 1.2.1.59 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11321512&form=6&db=m Relation between expression of TNF alpha, iNOS, VEGF mRNA and development of heart failure after experimental myocardial infarction in rats. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 1.2.1.59 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23389042&form=6&db=m Validation of reference genes for the determination of platelet transcript level in healthy individuals and in patients with the history of myocardial infarction. diagnostic usage,unassigned 2,0 1.2.1.59 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32934949&form=6&db=m Increased Expression Level of Long Noncoding RNA H19 in Plasma of Patients with Myocardial Infarction. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23527007&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Myocarditis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26021171&form=6&db=m [Selection of reference genes for transcription analysis for myocarditis studies]. ongoing research,therapeutic application,unassigned 1,1,0 1.2.1.59 Myoclonic Epilepsies, Progressive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9587422&form=6&db=m Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: a possible mechanism contributing to CAG-triplet diseases. unassigned - 1.2.1.59 Myoclonic Epilepsies, Progressive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12722924&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase and endothelin-1 immunoreactivity is associated with cerebral white matter damage in dentatorubral-pallidoluysian atrophy. causal interaction,unassigned 3,0 1.2.1.59 nad(p)h oxidase (h2o2-forming) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16778134&form=6&db=m Novel effect of oxidized low-density lipoprotein: cellular ATP depletion via downregulation of glyceraldehyde-3-phosphate dehydrogenase. unassigned - 1.2.1.59 Nasal Polyps http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12930694&form=6&db=m [Relationship between expressions of GATA-3 and interleukin-5 in nasal polyps] causal interaction,diagnostic usage,ongoing research,unassigned 1,4,3,0 1.2.1.59 Nasal Polyps http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19015448&form=6&db=m Expression of neutrophil gelatinase-associated lipocalin in nasal polyps. diagnostic usage,unassigned 3,0 1.2.1.59 Nasopharyngeal Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32627648&form=6&db=m MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 2,1,1,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8650074&form=6&db=m There are multiple forms of glyceraldehyde-3-phosphate dehydrogenase in prostate cancer cells and normal prostate tissue. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11139316&form=6&db=m Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases. ongoing research,unassigned 2,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15181008&form=6&db=m Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines. ongoing research,unassigned 2,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21827717&form=6&db=m Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22350014&form=6&db=m Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25625240&form=6&db=m Colon cancer stem cell markers CD44 and CD133 in patients with colorectal cancer and synchronous hepatic metastases. diagnostic usage,unassigned 4,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27878251&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression. causal interaction,ongoing research,unassigned 4,1,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30209795&form=6&db=m Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases. causal interaction,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31257027&form=6&db=m BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,1,3,1 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31564201&form=6&db=m Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31700673&form=6&db=m Single-cell protein profiling in microchambers with barcoded beads. unassigned - 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31796664&form=6&db=m Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,1,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33379345&form=6&db=m Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33575432&form=6&db=m Human-specific GAPDH qRT-PCR is an accurate and sensitive method of xenograft metastasis quantification. unassigned - 1.2.1.59 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33615312&form=6&db=m Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review. causal interaction,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1131821&form=6&db=m Enzyme activities at the surface of intact Ehrlich tumor cells with albumin in the isotonic assay medium. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2050029&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase and other enzymatic activity in normal mouse lung and in lung tumors. ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2105842&form=6&db=m Isolation and characterization of complementary DNA clones corresponding to genes induced in mouse epidermis in vivo by tumor promoters. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,1,3 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2121331&form=6&db=m Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues. causal interaction,diagnostic usage,unassigned 3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2736253&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase is a microtubule binding protein in a human colon tumor cell line. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3180054&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4332723&form=6&db=m Properties of the glyceraldehyde-3-phosphate dehydrogenase from Ehrlich ascites tumor cells. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6295653&form=6&db=m Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7584597&form=6&db=m Interaction of calcyclin and its cyanogen bromide fragments with annexin II and glyceraldehyde 3-phosphate dehydrogenase. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7590662&form=6&db=m Differential display and integrin alpha 6 messenger RNA overexpression in hepatocellular carcinoma. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7671226&form=6&db=m Alteration of glyceraldehyde-3-phosphate dehydrogenase activity and messenger RNA content by androgen in human prostate carcinoma cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8481901&form=6&db=m Association of glyceraldehyde-3-phosphate dehydrogenase expression with cell motility and metastatic potential of rat prostatic adenocarcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8533007&form=6&db=m Protein thiol modification and apoptotic cell death as cGMP-independent nitric oxide (NO) signaling pathways. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8636981&form=6&db=m Enhancement of hammerhead ribozyme catalysis by glyceraldehyde-3-phosphate dehydrogenase. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8650074&form=6&db=m There are multiple forms of glyceraldehyde-3-phosphate dehydrogenase in prostate cancer cells and normal prostate tissue. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8801721&form=6&db=m A reverse transcription-quantitative competitive polymerase chain reaction (RT-qcPCR) technique to measure cytokine gene expression in domestic mammals. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9144370&form=6&db=m Modulatory effect of mycobacterium cell wall extract (Regressin) on lymphocyte blastogenic activity and macrophage cytokine gene transcription in swine. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9203508&form=6&db=m Quantitation of vascular endothelial growth factor mRNA levels in human breast tumors and metastatic lymph nodes. causal interaction,diagnostic usage,ongoing research,unassigned 2,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9368510&form=6&db=m Retinoic acid receptors alpha, beta and gamma, and cellular retinol binding protein-I expression in breast fibrocystic disease and cancer. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9450641&form=6&db=m Inactivation of glyceraldehyde-3-phosphate dehydrogenase of human malignant cells by methylglyoxal. causal interaction,ongoing research,unassigned 1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9468581&form=6&db=m Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,3 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9570831&form=6&db=m Quantitation of estrogen receptor mRNA copy numbers in breast cancer cell lines and tumors. diagnostic usage,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9661888&form=6&db=m Detection and quantitation of circulating cancer cells in the peripheral blood of lung cancer patients. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9826470&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10364451&form=6&db=m Direct comparison of GAPDH, beta-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia. ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10471520&form=6&db=m Quantitative PCR analysis of c-erb B-2 (HER2/neu) gene amplification and comparison with p185(HER2/neu) protein expression in breast cancer drill biopsies. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10544038&form=6&db=m Reduced mRNA expression of the DNA demethylase, MBD2, in human colorectal and stomach cancers. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10607405&form=6&db=m Upregulation of glyceraldehyde-3-phosphate dehydrogenase mRNA in the spleen of tumor-bearing mice. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10645776&form=6&db=m Antisense oligodeoxynucleotide of glyceraldehyde-3-phosphate dehydrogenase gene inhibits cell proliferation and induces apoptosis in human cervical carcinoma cell lines. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10718379&form=6&db=m Role of endogenous nitric oxide in TNF-alpha and IL-1beta generation in hepatic ischemia-repefusion. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10720061&form=6&db=m Cytokine profiles in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathy. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10873024&form=6&db=m Treatment of inflammatory bowel disease in a rodent model with the intestinal growth factor glucagon-like peptide-2. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10885609&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase gene expression in human breast cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10897012&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10902805&form=6&db=m Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11011077&form=6&db=m HCV RNA levels in hepatocellular carcinomas and adjacent non-tumorous livers. causal interaction,diagnostic usage,unassigned 1,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11051224&form=6&db=m Telomerase RNA as a detection marker in the serum of breast cancer patients. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11059752&form=6&db=m Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11076659&form=6&db=m Gene expression profiles in thyroid carcinomas. diagnostic usage,ongoing research,unassigned 2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11113367&form=6&db=m Expression of vascular endothelial growth factor isoforms and platelet-derived endothelial cell growth factor in bladder cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11212261&form=6&db=m Expression of estrogen receptor (ER) subtypes and ERbeta isoforms in colon cancer. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11231991&form=6&db=m Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas. causal interaction,diagnostic usage,unassigned 4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11476540&form=6&db=m Ribosomal 18S RNA prevails over glyceraldehyde-3-phosphate dehydrogenase and beta-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11526511&form=6&db=m Alterations of repeated sequences in 5' upstream and coding regions in colorectal tumors from patients with hereditary nonpolyposis colorectal cancer and Turcot syndrome. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11782386&form=6&db=m Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization. diagnostic usage,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11848476&form=6&db=m Transcriptional profiling of cell lines derived from an orthotopic pancreatic tumor model reveals metastasis-associated genes. causal interaction,diagnostic usage,unassigned 1,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11940202&form=6&db=m Overexpression of osteopontin in hepatocellular carcinoma. causal interaction,diagnostic usage,unassigned 4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11955624&form=6&db=m Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11960638&form=6&db=m Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12168836&form=6&db=m High bad and bcl-xL gene expression and combined bad, bcl-xL, bax and bcl-2 mRNA levels: molecular predictors for survival of stage 2 soft tissue sarcoma patients. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,2,2 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12496918&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in late pathological stage human prostate cancer. diagnostic usage,ongoing research,therapeutic application,unassigned 4,4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12498774&form=6&db=m Enhanced gene expression in breast cancer cells in vitro and tumors in vivo. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12553051&form=6&db=m Selection of an internal control gene for quantitation of mRNA in colonic tissues. causal interaction,ongoing research,unassigned 4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14534714&form=6&db=m Protein and gene expression of tumor-associated antigen RCAS1 in esophageal squamous cell carcinoma. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14579739&form=6&db=m Selection of candidate housekeeping controls in tomato plants using EST data. diagnostic usage,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14730345&form=6&db=m Thioredoxin, a regulator of gene expression. causal interaction,diagnostic usage,unassigned 1,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15079082&form=6&db=m Identification of GAPDH as a protein target of the saframycin antiproliferative agents. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15133843&form=6&db=m Construction of human liver cancer vascular endothelium cDNA expression library and screening of the endothelium-associated antigen genes. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15181008&form=6&db=m Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines. ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15533718&form=6&db=m Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. causal interaction,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15565546&form=6&db=m Identification of various exon combinations of the ews/fli1 translocation: an optimized RT-PCR method for paraffin embedded tissue -- a report by the CWS-study group. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15614045&form=6&db=m Persistence of multiple tumor-specific T-cell clones is associated with complete tumor regression in a melanoma patient receiving adoptive cell transfer therapy. ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15867372&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase binds to the AU-Rich 3' untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells: possible role in CSF-1 posttranscriptional regulation and tumor phenotype. causal interaction,ongoing research,unassigned 2,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15914584&form=6&db=m Potassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal disease. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16231708&form=6&db=m Cytokine mRNA quantification in duodenal mucosa from dogs with chronic enteropathies by real-time reverse transcriptase polymerase chain reaction. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16319328&form=6&db=m Choice of endogenous control for gene expression in nonsmall cell lung cancer. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16392037&form=6&db=m Quantitation of O6-methylguanine-DNA methyltransferase gene messenger RNA in gliomas by means of real-time RT-PCR and clinical response to nitrosoureas. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16515701&form=6&db=m The Effect of Bisphosphonates on gene expression: GAPDH as a housekeeping or a new target gene? causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16524844&form=6&db=m Partial volume rat lung irradiation: Temporal fluctuations of in-field and out-of-field DNA damage and inflammatory cytokines following irradiation. diagnostic usage,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16638860&form=6&db=m Reduced plasma RNA integrity in nasopharyngeal carcinoma patients. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16963713&form=6&db=m Cytokine gene signatures in neural tissue of horses with equine protozoal myeloencephalitis or equine herpes type 1 myeloencephalopathy. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17074177&form=6&db=m [Selection and quantitative detection of target genes in oral squamous cell carcinoma] causal interaction,diagnostic usage,ongoing research,unassigned 3,4,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17114915&form=6&db=m Dissociation between tumor shrinkage and hormonal response during somatostatin analog treatment in an acromegalic patient: preferential expression of somatostatin receptor subtype 3. diagnostic usage,ongoing research,unassigned 4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17190429&form=6&db=m [Quantitative analysis of epidermal growth factor receptor mRNA in laryngeal carcinoma by reverse transcription-real time polymerase chain reaction with TagMan probe] diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17373842&form=6&db=m HDM2-binding partners: interaction with translation elongation factor EF1alpha. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17381682&form=6&db=m Development of a microarray for studying porcine cytokine production in blood mononuclear cells and intestinal biopsies. diagnostic usage,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17390034&form=6&db=m Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17540040&form=6&db=m Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17540725&form=6&db=m Involvement of glyceraldehyde-3-phosphate dehydrogenase in tumor necrosis factor-related apoptosis-inducing ligand-mediated death of thyroid cancer cells. causal interaction,ongoing research,therapeutic application,unassigned 1,4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17597534&form=6&db=m GAPDH is not regulated in human glioblastoma under hypoxic conditions. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,2 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17609619&form=6&db=m High level of ezrin mRNA expression in an osteosarcoma biopsy sample with lung metastasis. causal interaction,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17652962&form=6&db=m Increased translocator protein (TSPO) mRNA levels in colon but not in rectum carcinoma. diagnostic usage,ongoing research,therapeutic application,unassigned 2,3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17695449&form=6&db=m Expression of MMP-10 in lung cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18076071&form=6&db=m Nitroxyl inhibits breast tumor growth and angiogenesis. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18088474&form=6&db=m [Monitoring IgH levels in patients with B-cell malignancy by real-time quantitative PCR after hematopoietic stem cell transplantation and its significance] diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18158066&form=6&db=m Higher tumor to benign ratio of the androgen receptor mRNA expression associates with prostate cancer progression after radical prostatectomy. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18191230&form=6&db=m Quantitative real-time RT-PCR measurement of cytokine mRNA expression in the skin of normal cats and cats with allergic skin disease. ongoing research,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18252827&form=6&db=m Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18515332&form=6&db=m Decreased expression of cytochromes P450 1A2, 2E1, and 3A4 and drug transporters Na+-taurocholate-cotransporting polypeptide, organic cation transporter 1, and organic anion-transporting peptide-C correlates with the progression of liver fibrosis in chronic hepatitis C patients. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18651557&form=6&db=m Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,2,1 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18708368&form=6&db=m The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18765550&form=6&db=m Molecular diagnosis of sentinel lymph node metastases in cervical cancer using squamous cell carcinoma antigen. diagnostic usage,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18771724&form=6&db=m Covalent modification of proteins by green tea polyphenol (-)-epigallocatechin-3-gallate through autoxidation. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18974881&form=6&db=m A novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19036168&form=6&db=m Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR. causal interaction,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19144146&form=6&db=m Absence of GAPDH regulation in tumor-cells of different origin under hypoxic conditions in - vitro. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19161537&form=6&db=m Expression of CPEB, GAPDH and U6snRNA in cervical and ovarian tissue during cancer development. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19318579&form=6&db=m Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells. causal interaction,ongoing research,unassigned 1,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19368977&form=6&db=m Development and validation of cytokine quantitative, real time RT-PCR assays for characterization of Asian elephant immune responses. diagnostic usage,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19628630&form=6&db=m Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines. causal interaction,ongoing research,therapeutic application,unassigned 3,4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19650912&form=6&db=m Reference gene selection for head and neck squamous cell carcinoma gene expression studies. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19701498&form=6&db=m Cancer abolishes the tissue type-specific differences in the phenotype of energetic metabolism. diagnostic usage,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19747091&form=6&db=m Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19903463&form=6&db=m Molecular analysis and prognostic impact of the novel apoptotic gene BCL2L12 in gastric cancer. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19937139&form=6&db=m Glyceraldehyde-3-phosphate, a glycolytic intermediate, plays a key role in controlling cell fate via inhibition of caspase activity. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20044597&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20122155&form=6&db=m Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20393016&form=6&db=m 3-Bromopyruvate induces endoplasmic reticulum stress, overcomes autophagy and causes apoptosis in human HCC cell lines. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20511187&form=6&db=m Identification of valid endogenous control genes for determining gene expression in human glioma. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20552634&form=6&db=m The mitochondrial bioenergetic capacity of carcinomas. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20620471&form=6&db=m Protective effects of Toll-like receptor 4 inhibitor eritoran on renal ischemia-reperfusion injury. causal interaction,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20622334&form=6&db=m [Proteomic analysis of morphine rabbit myocardium with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry] diagnostic usage,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20682026&form=6&db=m A sequence-based approach to identify reference genes for gene expression analysis. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20727968&form=6&db=m The diverse functions of GAPDH: Views from different subcellular compartments. causal interaction,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20880300&form=6&db=m Relative down-regulation of apoptosis and autophagy genes in colorectal cancer. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20941832&form=6&db=m Functional and molecular characterization of glioblastoma multiforme-derived cancer stem cells. causal interaction,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21524534&form=6&db=m Technical note: Validation of candidate reference genes for normalization of quantitative PCR in bovine mammary epithelial cells responding to inflammatory stimuli. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21749859&form=6&db=m Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells. causal interaction,ongoing research,unassigned 3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21827717&form=6&db=m Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22357885&form=6&db=m Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22614725&form=6&db=m On the Relevance of Glycolysis Process on Brain Gliomas. causal interaction,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22668015&form=6&db=m Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,3 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22847419&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,2,1 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22851445&form=6&db=m Basic Biology of GAPDH. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22869254&form=6&db=m Removing the cells from adult bone marrow derived stem cell therapy does not eliminate cardioprotection. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22884252&form=6&db=m Two-stage hepatectomy with effective perioperative chemotherapy does not induce tumor growth or growth factor expression in liver metastases from colorectal cancer. causal interaction,diagnostic usage,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22964488&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22964641&form=6&db=m CIB1 prevents nuclear GAPDH accumulation and non-apoptotic tumor cell death via AKT and ERK signaling. causal interaction,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23060553&form=6&db=m IGF1R gene expression as a predictive marker of response to ionizing radiation for patients with locally advanced HPV16-positive cervical cancer. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23155364&form=6&db=m Quantification of BCR-ABL mRNA in plasma/serum of patients with chronic myelogenous leukemia. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23239881&form=6&db=m Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23377192&form=6&db=m Cytotoxicity of chemotherapeutic agents in glyceraldehyde-3-phosphate dehydrogenase-depleted human lung carcinoma A549 cells with the accelerated senescence phenotype. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23379564&form=6&db=m Localization of non-native D-glyceraldehyde-3-phosphate dehydrogenase in growing and apoptotic HeLa cells. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23445303&form=6&db=m Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a therapeutic target. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23597945&form=6&db=m Tumor hypoxia and metabolism -- towards novel anticancer approaches. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23620736&form=6&db=m The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (GACC) genes correlates with cancer stage and poor survival in patients with solid tumors. causal interaction,diagnostic usage,unassigned 4,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23645209&form=6&db=m GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23811755&form=6&db=m Evaluation of potential reference genes for qRT-PCR studies in human hepatoma cell lines treated with TNF-?. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,3 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24362262&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal. ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24367685&form=6&db=m C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia. causal interaction,therapeutic application,unassigned 1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24450150&form=6&db=m [Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans]. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24496476&form=6&db=m Modulation of glyceraldehyde-3-phosphate dehydrogenase activity by surface functionalized quantum dots. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24778322&form=6&db=m Influenza virus infection elicits protective antibodies and T cells specific for host cell antigens also expressed as tumor-associated antigens: a new view of cancer immunosurveillance. ongoing research,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24851941&form=6&db=m Expression Profile and Subcellular Localization of GAPDH in the Smooth Muscle Cells of Human Atherosclerotic Plaque: An Immunohistochemical and Ultrastructural Study with Biological Therapeutic Perspectives. causal interaction,ongoing research,unassigned 4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24859296&form=6&db=m Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25034412&form=6&db=m Modulatory roles of glycolytic enzymes in cell death. therapeutic application,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25063577&form=6&db=m Analyzing time-series microarray data reveals key genes in spinal cord injury. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25188891&form=6&db=m Metabolic markers and HSP60 in chemonaive serous solid ovarian cancer versus ascites. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25307767&form=6&db=m Reference gene selection for quantitative real-time reverse-transcriptase PCR in orchardgrass subjected to various abiotic stresses. ongoing research,therapeutic application,unassigned 1,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25308277&form=6&db=m Chemical targeting of GAPDH moonlighting function in cancer cells reveals its role in tubulin regulation. ongoing research,therapeutic application,unassigned 2,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25394713&form=6&db=m GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-?B-dependent induction of HIF-1? causal interaction,diagnostic usage,unassigned 2,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25397880&form=6&db=m Detection of tumor cell-specific mRNA and protein in exosome-like microvesicles from blood and saliva. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25451934&form=6&db=m A Dimer Interface Mutation in Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Its Binding to AU-rich RNA. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25550585&form=6&db=m Deregulation of glyceraldehyde-3-phosphate dehydrogenase expression during tumor progression of human cutaneous melanoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,1 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25785838&form=6&db=m Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNF?-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25844669&form=6&db=m Inferring genome-wide functional modulatory network: a case study on NF-?B/RelA transcription factor. causal interaction,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25859407&form=6&db=m Critical protein GAPDH and its regulatory mechanisms in cancer cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25928893&form=6&db=m Association of Cone-Rod Homeobox Transcription Factor Messenger RNA With Pediatric Metastatic Retinoblastoma. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25944651&form=6&db=m Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25944804&form=6&db=m Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,3,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26136865&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase expression indicates higher survival rates in male patients with hepatitis B virus-accociated hepatocellular carcinoma and cirrhosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26167073&form=6&db=m TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26188100&form=6&db=m Smoking Modulates Gene Expression of Type I Collagen, Bone Sialoprotein, and Osteocalcin in Human Alveolar Bone. diagnostic usage,ongoing research,unassigned 1,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26190920&form=6&db=m Acetyl Eburicoic Acid from Laetiporus sulphureus var. miniatus Suppresses Inflammation in Murine Macrophage RAW 264.7 Cells. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26384826&form=6&db=m Consensus reference gene(s) for gene expression studies in human cancers: end of the tunnel visible? therapeutic application,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26452026&form=6&db=m High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma. causal interaction,diagnostic usage,unassigned 1,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26508976&form=6&db=m Antitumor Efficacy and Mechanism in Hepatoma H22-Bearing Mice of Brucea javanica Oil. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26528183&form=6&db=m Lactate does not activate NF-?B in oxidative tumor cells. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26586769&form=6&db=m Vitamin C Targets GAPDH to Kill KRAS- and BRAF-Mutant Cancer Cells. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26629320&form=6&db=m Disruption of NAD(+) binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactions. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26631806&form=6&db=m Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala). therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26869854&form=6&db=m Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells. causal interaction,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26911935&form=6&db=m Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27013493&form=6&db=m Dysregulated bioenergetics: a key regulator of joint inflammation. causal interaction,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27099857&form=6&db=m Alteration of GLIS3 gene expression pattern in patients with breast cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,4,4,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27185638&form=6&db=m GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,3,3,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27389089&form=6&db=m Identification of human serum protein targets of Qianggu Decoction () in primary type I osteoporosis based on tandem mass tag labeling and liquid chromatography-tandem mass spectrometry technology. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27501924&form=6&db=m Expression, purification and characterization of GAPDH-ChSase ABC I from Proteus vulgaris in Escherichia coli. ongoing research,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27678473&form=6&db=m In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27840795&form=6&db=m Chaperonin-Dendrimer Conjugates for siRNA Delivery. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27867269&form=6&db=m Platyphylloside Isolated From Betula platyphylla Inhibit Adipocyte Differentiation and Induce Lipolysis Via Regulating Adipokines Including PPAR? in 3T3-L1 Cells. causal interaction,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27878251&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression. causal interaction,ongoing research,unassigned 4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28225552&form=6&db=m Potential clinical significance of perioperative levels of mRNA in plasma from patients with cancer of the larynx or hypopharynx. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28382556&form=6&db=m Acute progressive paravascular placoid neuroretinopathy with negative-type electroretinography in paraneoplastic retinopathy. diagnostic usage,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28387968&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase. causal interaction,ongoing research,unassigned 3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28432433&form=6&db=m Glypican-3 mRNA expression level in Wilms tumor: correlation with histological type, stage, and outcome. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28451145&form=6&db=m Competitive method-based electrochemiluminescent assay with protein-nucleotide conversion for ratio detection to efficiently monitor the drug resistance of cancer cells. diagnostic usage,ongoing research,therapeutic application,unassigned 2,3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28608814&form=6&db=m Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study. diagnostic usage,ongoing research,unassigned 2,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28650490&form=6&db=m Hypoxia-induced tumor cell resistance is overcome by synergistic GAPDH-siRNA and chemotherapy co-delivered by long-circulating and cationic-interior liposomes. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28753256&form=6&db=m A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation. causal interaction,ongoing research,therapeutic application,unassigned 3,3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28962872&form=6&db=m UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism. causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29039977&form=6&db=m Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29171745&form=6&db=m Retracted: Resveratrol inhibits oesophageal adenocarcinoma cell proliferation via AMP-activated protein kinase signaling ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29225201&form=6&db=m 3-Bromopyruvate as a potential pharmaceutical in the light of experimental data. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29286140&form=6&db=m Identification of key genes implicated in the suppressive function of human FOXP3+CD25+CD4+ regulatory T cells through the analysis of time?series data. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29369729&form=6&db=m DEVELOPMENT AND VALIDATION OF QUANTITATIVE PCR ASSAYS TO MEASURE CYTOKINE TRANSCRIPT LEVELS IN THE FLORIDA MANATEE ( TRICHECHUS MANATUS LATIROSTRIS). diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29517391&form=6&db=m Evolution of GAPDH as a druggable target of tumor glycolysis? therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29664161&form=6&db=m Affinity-Driven Covalent Modulator of the Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Cascade. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29966509&form=6&db=m HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30077773&form=6&db=m GAPDH with NAD+-binding site mutation competitively inhibits the wild-type and affects glucose metabolism in cancer. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30195603&form=6&db=m Inhibiting a spinal cord signaling pathway protects against ischemia injury in rats. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30209795&form=6&db=m Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases. causal interaction,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30296496&form=6&db=m Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30395437&form=6&db=m Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3-Bromopyruvate Targets beyond Glycolysis. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30581507&form=6&db=m Correlation study of GAPDH, Bcl-2, and Bax protein immunoexpression in patients with colorectal adenocarcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,3 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30640524&form=6&db=m Trafficking of a multifunctional protein by endosomal micro-autophagy: linking two independent unconventional secretory pathways. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30700763&form=6&db=m Progesterone Treatment Attenuates Glycolytic Metabolism and Induces Senescence in Glioblastoma. ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30735319&form=6&db=m [The vascular endothelial growth factor in patients with advanced ovarian cancer on the background of chemotherapy according to the AP scheme.] causal interaction,diagnostic usage,ongoing research,unassigned 1,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30786811&form=6&db=m The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30827861&form=6&db=m GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30881377&form=6&db=m Pan-Cancer Analysis of TCGA Data Revealed Promising Reference Genes for qPCR Normalization. causal interaction,diagnostic usage,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30898012&form=6&db=m Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30917710&form=6&db=m The Effect of IL-26 on TNF-?-Induced CXCL8 Responses by Colonic Epithelial Cell Lines. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30966861&form=6&db=m Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30967137&form=6&db=m The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30975552&form=6&db=m Diagnostic and prognostic value of the detection of hTERT mRNA in renal tumors. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30990365&form=6&db=m Mitigation of cocaine-mediated mitochondrial damage, defective mitophagy and microglial activation by superoxide dismutase mimetics. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31027346&form=6&db=m Regulation of Autophagy by Nuclear GAPDH and Its Aggregates in Cancer and Neurodegenerative Disorders. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31133878&form=6&db=m Stressors Due to Handling Impair Gut Immunity in Meagre (Argyrosomus regius): The Compensatory Role of Dietary L-Tryptophan. ongoing research,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31239764&form=6&db=m Nuclear GAPDH is vital for hypoxia-induced hepatic stellate cell apoptosis and is indicative of aggressive hepatocellular carcinoma behavior. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31324208&form=6&db=m Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31387164&form=6&db=m Structural Study of Monomethyl Fumarate-Bound Human GAPDH. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31564201&form=6&db=m Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31567534&form=6&db=m Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31612140&form=6&db=m 2-Deoxyglucose and Newcastle Disease Virus Synergize to Kill Breast Cancer Cells by Inhibition of Glycolysis Pathway Through Glyceraldehyde3-Phosphate Downregulation. causal interaction,therapeutic application,unassigned 4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31696776&form=6&db=m STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31700673&form=6&db=m Single-cell protein profiling in microchambers with barcoded beads. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31796664&form=6&db=m Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31868102&form=6&db=m Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31983282&form=6&db=m DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32028064&form=6&db=m Discovery of novel glyceraldehyde-3-phosphate dehydrogenase inhibitor via docking-based virtual screening. causal interaction,ongoing research,therapeutic application,unassigned 4,1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32197454&form=6&db=m Identification and Quantification of Transient Receptor Potential Vanilloid 1 (TRPV1) in Equine Articular Tissue. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32214977&form=6&db=m Modulation of immunity and inflammatory gene expression in buffalo (Bubalus bubalis) with some digestive disorders. diagnostic usage,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32365590&form=6&db=m Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,3,1 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32424999&form=6&db=m Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,2 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32443898&form=6&db=m Cytokine Expression by Human Macrophage-Like Cells Derived from the Monocytic Cell Line THP-1 Differs Between Treatment With Milk from Preterm- and Term-Delivering Mothers and Pasteurized Donor Milk. diagnostic usage,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32505664&form=6&db=m Pharmacological targets and molecular mechanisms of plumbagin to treat colorectal cancer: A systematic pharmacology study. diagnostic usage,therapeutic application,unassigned 1,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32525764&form=6&db=m Elucidation of colon-protective efficacy of diosgenin in experimental TNBS-induced colitis: inhibition of NF-?B/IkB-? and Bax/Caspase-1 signaling pathways. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32627648&form=6&db=m MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 2,1,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32681951&form=6&db=m Expression of a heptelidic acid-insensitive recombinant GAPDH from Trichoderma virens, and its biochemical and biophysical characterization. therapeutic application,unassigned 3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32705257&form=6&db=m A frequent somatic mutation in the 3'UTR of GAPDH facilitates the development of ovarian cancer by creating a miR?125b binding site. causal interaction,ongoing research,unassigned 2,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32785215&form=6&db=m Relative quantification of BCL2 mRNA for diagnostic usage needs stable uncontrolled genes as reference. causal interaction,diagnostic usage,unassigned 2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32806075&form=6&db=m 3-Bromopyruvate-Conjugated Nanoplatform-Induced Pro-Death Autophagy for Enhanced Photodynamic Therapy against Hypoxic Tumor. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32866426&form=6&db=m Keratinocyte autophagy enables the activation of keratinocytes and fibroblasts and facilitates wound healing. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32880800&form=6&db=m Calcium Fructoborate Prevents Skin Cancer Development in Balb-c Mice: Next Part, Reverse Inflammation, and Metabolic Alteration. causal interaction,therapeutic application,unassigned 2,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32944178&form=6&db=m miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas. ongoing research,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33035689&form=6&db=m Diagnostic value of circulating cell-free mtDNA in patients with suspected thyroid cancer: ND4/ND1 ratio as a new potential plasma marker. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33140730&form=6&db=m [Expression of sperm-specific glyceraldehyde-3-phosphate dehydrogenase in melanoma cells changes their energy metabolism]. causal interaction,ongoing research,unassigned 1,4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33140880&form=6&db=m Ectophosphatase activity in the triple-negative breast cancer cell line MDA-MB-231. unassigned - 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33379345&form=6&db=m Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33430251&form=6&db=m Different Modulatory Effects of Four Methicillin-Resistant Staphylococcus aureus Clones on MG-63 Osteoblast-Like Cells. causal interaction,ongoing research,unassigned 1,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33457124&form=6&db=m GAPDH and PUM1: Optimal Housekeeping Genes for Quantitative Polymerase Chain Reaction-Based Analysis of Cancer Stem Cells and Epithelial-Mesenchymal Transition Gene Expression in Rectal Tumors. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33501690&form=6&db=m Validation of common reference genes stability in exosomal mRNA-isolated from liver and breast cancer cell lines. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33539530&form=6&db=m Diseasome and comorbidities complexities of SARS-CoV-2 infection with common malignant diseases. therapeutic application,unassigned 1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33545174&form=6&db=m Determining the quantitative relationship between glycolysis and GAPDH in cancer cells exhibiting Warburg effect. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,1 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33546324&form=6&db=m Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress. causal interaction,ongoing research,therapeutic application,unassigned 2,3,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33640700&form=6&db=m Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33651246&form=6&db=m The role of posttranslational modification in moonlighting glyceraldehyde-3-phosphate dehydrogenase structure and function. causal interaction,unassigned 4,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33817128&form=6&db=m Up-regulation of Key Glycolysis Proteins in Cancer Development. causal interaction,diagnostic usage,ongoing research,unassigned 2,1,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33850276&form=6&db=m Natural product 1,2,3,4,6-penta-O-galloyl-?-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase. therapeutic application,unassigned 2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33978420&form=6&db=m Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells. ongoing research,therapeutic application,unassigned 3,2,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34048311&form=6&db=m MicroRNA let-7i-3p affects osteoblast differentiation in ankylosing spondylitis via targeting PDK1. diagnostic usage,ongoing research,therapeutic application,unassigned 2,2,1,0 1.2.1.59 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34527050&form=6&db=m Aminoquinolines as Translational Models for Drug Repurposing: Anticancer Adjuvant Properties and Toxicokinetic-Related Features. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Neoplastic Cells, Circulating http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28608814&form=6&db=m Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study. diagnostic usage,ongoing research,unassigned 2,3,0 1.2.1.59 Nephritis, Hereditary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8793804&form=6&db=m Expression of type IV collagen alpha 3 and alpha 4 chain mRNA in X-linked Alport syndrome. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Nephrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9175058&form=6&db=m Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,4 1.2.1.59 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8712219&form=6&db=m Increased mRNA expression of metalloproteinase-9 in peripheral blood monocytes from patients with immunoglobulin A nephropathy. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.2.1.59 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31759082&form=6&db=m Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease. therapeutic application,unassigned 1,0 1.2.1.59 Neuralgia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18493752&form=6&db=m Proteomic analysis of differential proteins related to the neuropathic pain and neuroprotection in the dorsal root ganglion following its chronic compression in rats. causal interaction,unassigned 4,0 1.2.1.59 Neuralgia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20804730&form=6&db=m Identification and validation of reference genes for expression studies in a rat model of neuropathic pain. ongoing research,unassigned 3,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2121331&form=6&db=m Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues. causal interaction,diagnostic usage,unassigned 3,4,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9041562&form=6&db=m Possible involvement of ADP-ribosylation of particular enzymes in cell death induced by nitric oxide-donors in human neuroblastoma cells. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9407389&form=6&db=m Melatonin alters the metabolism of the beta-amyloid precursor protein in the neuroendocrine cell line PC12. therapeutic application,unassigned 3,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12576454&form=6&db=m Real-time analysis of tyrosine hydroxylase gene expression: a sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma. diagnostic usage,ongoing research,therapeutic application,unassigned 4,2,1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12960120&form=6&db=m Development of a real-time polymerase chain reaction assay for prediction of the uptake of meta-[(131)I]iodobenzylguanidine by neuroblastoma tumors. diagnostic usage,ongoing research,unassigned 2,3,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16297863&form=6&db=m NK sensitivity of neuroblastoma cells determined by a highly sensitive coupled luminescent method. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16942854&form=6&db=m A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19874799&form=6&db=m An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells. ongoing research,unassigned 3,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20022592&form=6&db=m A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. ongoing research,unassigned 4,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21624650&form=6&db=m Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery. ongoing research,unassigned 3,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21775503&form=6&db=m Novel mechanism of Hsp70 chaperone-mediated prevention of polyglutamine aggregates in a cellular model of huntington disease. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22788371&form=6&db=m Alterations in metabolism-related genes induced in SHSY5Y cells by okadaic acid exposure. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25805836&form=6&db=m Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26725192&form=6&db=m Active site cysteine-null glyceraldehyde-3-phosphate dehydrogenase (GAPDH) rescues nitric oxide-induced cell death. causal interaction,unassigned 4,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26748070&form=6&db=m Small molecules preventing GAPDH aggregation are therapeutically applicable in cell and rat models of oxidative stress. causal interaction,ongoing research,therapeutic application,unassigned 1,3,2,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26785692&form=6&db=m Homocysteine induces glyceraldehyde-3-phosphate dehydrogenase acetylation and apoptosis in the neuroblastoma cell line Neuro2a. ongoing research,therapeutic application,unassigned 1,1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28916476&form=6&db=m Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis. ongoing research,therapeutic application,unassigned 4,4,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29016861&form=6&db=m DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29777694&form=6&db=m GAPDH-targeted therapy - A new approach for secondary damage after traumatic brain injury on rats. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33996900&form=6&db=m Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and Neuroblastoma Cells. unassigned - 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34216695&form=6&db=m GAPDH siRNA Regulates SH-SY5Y Cell Apoptosis Induced by Exogenous ?-Synuclein Protein. ongoing research,unassigned 4,0 1.2.1.59 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34358965&form=6&db=m Prolyl oligopeptidase participates in the cytosine arabinoside-induced nuclear translocation of glyceraldehyde 3-phosphate dehydrogenase in a human neuroblastoma cell line. ongoing research,therapeutic application,unassigned 3,2,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8872471&form=6&db=m Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9213215&form=6&db=m Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology. causal interaction,diagnostic usage,unassigned 4,3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10407139&form=6&db=m New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase. causal interaction,diagnostic usage,unassigned 3,3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10740219&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase and apoptosis. ongoing research,unassigned 1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11205159&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11208907&form=6&db=m Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12428732&form=6&db=m Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders? causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12503091&form=6&db=m Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts. causal interaction,ongoing research,unassigned 4,2,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12657368&form=6&db=m Proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase: a possible site of action of antiapoptotic drugs. therapeutic application,unassigned 4,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15486605&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15822178&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. causal interaction,therapeutic application,unassigned 3,2,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16186172&form=6&db=m Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease. causal interaction,unassigned 4,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16574384&form=6&db=m GAPDH as a sensor of NO stress. causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17613523&form=6&db=m The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death. unassigned - 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19154771&form=6&db=m Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse. causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19445904&form=6&db=m Involvement of glyceraldehyde-3-phosphate dehydrogenase in rotenone-induced cell apoptosis: relevance to protein misfolding and aggregation. causal interaction,unassigned 3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20727968&form=6&db=m The diverse functions of GAPDH: Views from different subcellular compartments. causal interaction,unassigned 4,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22851452&form=6&db=m Multiple binding partners. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23651214&form=6&db=m Nuclear translocation and accumulation of glyceraldehyde-3-phosphate dehydrogenase involved in diclazuril-induced apoptosis in Eimeria tenella (E. tenella). causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23819039&form=6&db=m Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis. causal interaction,ongoing research,unassigned 2,1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24018444&form=6&db=m Properties and functional diversity of glyceraldehyde-3-phosphate dehydrogenase. unassigned - 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24059224&form=6&db=m Effect of Resveratrol and Tiron on The Inactivation of Glyceraldehyde-3-Phosphate Dehydrogenase Induced by Superoxide Anion Radical. causal interaction,unassigned 4,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24662796&form=6&db=m The biological significance of oxidative modifications of cysteine residues in proteins illustrated with the example of glyceraldehyde-3-phosphate dehydrogenase. causal interaction,unassigned 3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24671416&form=6&db=m Structural Characterization of Heparin-induced GAPDH Protofibrils Preventing ?-synuclein Oligomeric Species Toxicity. causal interaction,ongoing research,therapeutic application,unassigned 4,1,1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24988620&form=6&db=m [The biological significance of oxidative modifications of cysteine residues in proteins illustrated with the example of glyceraldehyde-3-phosphate dehydrogenase]. causal interaction,unassigned 3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25022884&form=6&db=m A Proteomic Approach for the Involvement of the GAPDH in Alzheimer Disease in the Blood of Moroccan FAD Cases. causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,2,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27143373&form=6&db=m [Oxidative modification of glyceraldehyde-3-phosphate dehydrogenase influences its interaction with endogenous neuroprotector isatin]. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27215901&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase: Aggregation mechanisms and impact on amyloid neurodegenerative diseases. causal interaction,ongoing research,unassigned 4,3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30254002&form=6&db=m Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30658140&form=6&db=m Glycation of ?-synuclein amplifies the binding with glyceraldehyde-3-phosphate dehydrogenase. causal interaction,unassigned 1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30966861&form=6&db=m Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease. unassigned - 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31027346&form=6&db=m Regulation of Autophagy by Nuclear GAPDH and Its Aggregates in Cancer and Neurodegenerative Disorders. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,4 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31826695&form=6&db=m Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis. unassigned - 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32646244&form=6&db=m Moonlighting glyceraldehyde-3-phosphate dehydrogenase: posttranslational modification, protein and nucleic acid interactions in normal cells and in human pathology. causal interaction,ongoing research,unassigned 3,1,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33385367&form=6&db=m Glycation of glyceraldehyde-3-phosphate dehydrogenase inhibits the binding with ?-synuclein and RNA. diagnostic usage,unassigned 3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34196425&form=6&db=m Increased expression of GAPDH in cynomolgus monkeys with spontaneous cognitive decline and amyloidopathy reminiscent of an Alzheimer's-type disease is reflected in the circulation. causal interaction,unassigned 3,0 1.2.1.59 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34406601&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase Facilitates Macroautophagic Degradation of Mutant Huntingtin Protein Aggregates. therapeutic application,unassigned 1,0 1.2.1.59 Neuroectodermal Tumors, Primitive, Peripheral http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30474100&form=6&db=m Ultrasensitive quantification of tumor mRNAs in extracellular vesicles with an integrated microfluidic digital analysis chip. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Neuroendocrine Tumors http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17456737&form=6&db=m GeneChip, geNorm, and gastrointestinal tumors: novel reference genes for real-time PCR. causal interaction,diagnostic usage,therapeutic application,unassigned 1,1,1,0 1.2.1.59 Neuroendocrine Tumors http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27802291&form=6&db=m ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology. diagnostic usage,unassigned 1,0 1.2.1.59 Nevus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12544092&form=6&db=m Gene expression profiling of melanocytic lesions. causal interaction,unassigned 1,0 1.2.1.59 Nevus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30537064&form=6&db=m Prognostic implications of markers of the metabolic phenotype in human cutaneous melanoma. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 1.2.1.59 Non-alcoholic Fatty Liver Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29511485&form=6&db=m Protein interaction mapping interpretation of none alcoholic fatty liver disease model of rats after fat diet feeding. therapeutic application,unassigned 1,0 1.2.1.59 Non-alcoholic Fatty Liver Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32597296&form=6&db=m The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB. ongoing research,unassigned 1,0 1.2.1.59 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3178770&form=6&db=m Adipose-tissue-specific increase in glyceraldehyde-3-phosphate dehydrogenase activity and mRNA amounts in suckling pre-obese Zucker rats. Effect of weaning. ongoing research,unassigned 4,0 1.2.1.59 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14731357&form=6&db=m [Apolipoprotein E gene expression in peripheral blood monocyte in children with obesity] causal interaction,diagnostic usage,unassigned 2,1,0 1.2.1.59 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19997558&form=6&db=m Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications. causal interaction,unassigned 3,0 1.2.1.59 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25579404&form=6&db=m Comparative secretome analysis of rat stomach under different nutritional status. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32597296&form=6&db=m The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB. ongoing research,unassigned 1,0 1.2.1.59 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33193860&form=6&db=m An overview on recent in vivo biological application of cerium oxide nanoparticles. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 1.2.1.59 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33330591&form=6&db=m High-Fat Diet Alters the Expression of Reference Genes in Male Mice. causal interaction,unassigned 3,0 1.2.1.59 Onchocerciasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15955451&form=6&db=m Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH). therapeutic application,unassigned 1,0 1.2.1.59 Oncogene Addiction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23603840&form=6&db=m Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Osteoarthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17284318&form=6&db=m Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. ongoing research,therapeutic application,unassigned 2,2,0 1.2.1.59 Osteoarthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23124986&form=6&db=m Monosodium iodoacetate induces apoptosis via the mitochondrial pathway involving ROS production and caspase activation in rat chondrocytes in vitro. therapeutic application,unassigned 1,0 1.2.1.59 Osteophyte http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32510505&form=6&db=m Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats. causal interaction,unassigned 3,0 1.2.1.59 Osteoporosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27389089&form=6&db=m Identification of human serum protein targets of Qianggu Decoction () in primary type I osteoporosis based on tandem mass tag labeling and liquid chromatography-tandem mass spectrometry technology. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,4 1.2.1.59 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9874511&form=6&db=m Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines. diagnostic usage,ongoing research,unassigned 1,2,0 1.2.1.59 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16253101&form=6&db=m Biological evaluation of chitosan nanofiber membrane for guided bone regeneration. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22855186&form=6&db=m Identification of valid reference housekeeping genes for gene expression analysis in tumor neovascularization studies. ongoing research,unassigned 2,0 1.2.1.59 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25063577&form=6&db=m Analyzing time-series microarray data reveals key genes in spinal cord injury. unassigned - 1.2.1.59 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27826623&form=6&db=m [Corrigendum] Adenovirus-mediated overexpression of BMP-9 inhibits human osteosarcoma cell growth and migration through downregulation of the PI3K/AKT pathway. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32945076&form=6&db=m Decreased long non-coding RNA lincFOXF1 indicates poor progression and promotes cell migration and metastasis in osteosarcoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,1 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15867372&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase binds to the AU-Rich 3' untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells: possible role in CSF-1 posttranscriptional regulation and tumor phenotype. causal interaction,ongoing research,unassigned 2,3,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17108216&form=6&db=m Quantification of total plasma cell-free DNA in ovarian cancer using real-time PCR. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,1,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18708368&form=6&db=m The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,4,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21979951&form=6&db=m Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22265591&form=6&db=m Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response. diagnostic usage,unassigned 2,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24252137&form=6&db=m Metabolic markers GAPDH, PKM2, ATP5B and BEC-index in advanced serous ovarian cancer. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30174558&form=6&db=m Cytosolic and Transmembrane Protein Extraction Methods of Breast and Ovarian Cancer Cells: A Comparative Study. diagnostic usage,ongoing research,unassigned 3,4,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32705257&form=6&db=m A frequent somatic mutation in the 3'UTR of GAPDH facilitates the development of ovarian cancer by creating a miR?125b binding site. causal interaction,ongoing research,unassigned 2,3,0 1.2.1.59 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32754300&form=6&db=m Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer. diagnostic usage,unassigned 3,0 1.2.1.59 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12138232&form=6&db=m Ribosomal highly basic 23-kDa protein as a reliable standard for gene expression analysis. causal interaction,diagnostic usage,unassigned 3,3,0 1.2.1.59 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16441422&form=6&db=m Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,3,0 1.2.1.59 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30296496&form=6&db=m Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31324208&form=6&db=m Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 1.2.1.59 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31927104&form=6&db=m Comparative peptidome profiling reveals critical roles for peptides in the pathology of pancreatic cancer. causal interaction,unassigned 4,0 1.2.1.59 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9207211&form=6&db=m Pancreatic GAPDH gene expression during ontogeny and acute pancreatitis induced by caerulein. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 1.2.1.59 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12138232&form=6&db=m Ribosomal highly basic 23-kDa protein as a reliable standard for gene expression analysis. causal interaction,diagnostic usage,unassigned 3,3,0 1.2.1.59 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15115683&form=6&db=m Maldi-TOF analysis of portal sera of pancreatic cancer patients: identification of diabetogenic and antidiabetogenic peptides. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16441422&form=6&db=m Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,3,0 1.2.1.59 Papilloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18291599&form=6&db=m On the mechanism of phenotypic conversion of human cervical adenocarcinoma HeLa cells surviving infection by influenza B virus: Potential implications for biological management of adenocarcinomas. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4047509&form=6&db=m Inhibition of glyceraldehyde-3-phosphate dehydrogenase in tissues of the rat by acrylamide and related compounds. therapeutic application,unassigned 1,0 1.2.1.59 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6100457&form=6&db=m Unimpaired energy metabolism in experimental neuropathy induced by p-bromophenylacetylurea. unassigned - 1.2.1.59 Paramyxoviridae Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8798741&form=6&db=m Specific interaction in vitro and in vivo of glyceraldehyde-3-phosphate dehydrogenase and LA protein with cis-acting RNAs of human parainfluenza virus type 3. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,3,1 1.2.1.59 Paramyxoviridae Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10729139&form=6&db=m Specific phosphorylated forms of glyceraldehyde 3-phosphate dehydrogenase associate with human parainfluenza virus type 3 and inhibit viral transcription in vitro. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Parasitic Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10712729&form=6&db=m Production of Sm37-GAPDH, a major therapeutical target in human schistosomiasis. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Parasitic Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12613827&form=6&db=m Development and characterization of an immobilized enzyme reactor based on glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies. therapeutic application,unassigned 4,0 1.2.1.59 Parasitic Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32472399&form=6&db=m Enhancing the Stability of Haemonchus contortus Glyceraldehyde-3-Phosphate Dehydrogenase and Binding of Host Albumin to the Parasite Enzyme. therapeutic application,unassigned 2,0 1.2.1.59 Parathyroid Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10843188&form=6&db=m Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11031081&form=6&db=m Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. causal interaction,unassigned 2,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12428732&form=6&db=m Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders? causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12880486&form=6&db=m Peroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson's disease. therapeutic application,unassigned 1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15486605&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16574384&form=6&db=m GAPDH as a sensor of NO stress. causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21314614&form=6&db=m Novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase: covalent modification of NAD-binding site by aromatic thiols. causal interaction,unassigned 1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21706495&form=6&db=m Identification of tyrosine nitration in UCH-L1 and GAPDH. causal interaction,unassigned 3,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21736921&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase: activity inhibition and protein overexpression in rotenone models for Parkinson's disease. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22134915&form=6&db=m Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in ?-synuclein aggregation. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23696560&form=6&db=m Deprenyl enhances the teratogenicity of hydroxyurea in organogenesis stage mouse embryos. therapeutic application,unassigned 3,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24671416&form=6&db=m Structural Characterization of Heparin-induced GAPDH Protofibrils Preventing ?-synuclein Oligomeric Species Toxicity. causal interaction,ongoing research,therapeutic application,unassigned 4,1,1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26258539&form=6&db=m Genetic variants in GAPDH confer susceptibility to sporadic Parkinson's disease in a Chinese Han population. causal interaction,unassigned 3,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26303854&form=6&db=m Parkinson disease: GAPDH mutations can increase or decrease the risk of PD. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27859598&form=6&db=m Reduction of GAPDH in lenses of Parkinson's disease patients: A possible new biomarker. causal interaction,therapeutic application,unassigned 3,2,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28830811&form=6&db=m Inactivation of glyceraldehyde-3-phosphate dehydrogenase by the dopamine metabolite, 3,4-dihydroxyphenylacetaldehyde. unassigned - 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29408361&form=6&db=m Binding of alpha-synuclein to partially oxidized glyceraldehyde-3-phosphate dehydrogenase induces subsequent inactivation of the enzyme. causal interaction,unassigned 1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29886133&form=6&db=m GAPDH rs1136666 SNP indicates a high risk of Parkinson's disease. causal interaction,diagnostic usage,unassigned 2,2,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30254002&form=6&db=m Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30966861&form=6&db=m Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease. unassigned - 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30983487&form=6&db=m Age-dependent accumulation of oligomeric SNCA/?-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31759082&form=6&db=m Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease. therapeutic application,unassigned 1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32286126&form=6&db=m A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons. ongoing research,unassigned 1,0 1.2.1.59 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33300446&form=6&db=m Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441G mice. unassigned - 1.2.1.59 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19445904&form=6&db=m Involvement of glyceraldehyde-3-phosphate dehydrogenase in rotenone-induced cell apoptosis: relevance to protein misfolding and aggregation. causal interaction,unassigned 3,0 1.2.1.59 Peripheral Nerve Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21863315&form=6&db=m Quantification of Gene Expression after Painful Nerve Injury: Validation of Optimal Reference Genes. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Persistent Hyperplastic Primary Vitreous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31462148&form=6&db=m Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease. ongoing research,unassigned 2,0 1.2.1.59 Pheochromocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16178438&form=6&db=m [Expression of adrenomedullin and its receptor mRNA in the tissues of normal adrenal medulla and pheochromocytoma] therapeutic application,unassigned 1,0 1.2.1.59 Pheochromocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21736921&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase: activity inhibition and protein overexpression in rotenone models for Parkinson's disease. causal interaction,therapeutic application,unassigned 3,4,0 1.2.1.59 Phytoplasma Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21637692&form=6&db=m The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthoraperniciosa, the causal agent of witches' broom disease of Theobroma cacao. ongoing research,therapeutic application,unassigned 1,1,0 1.2.1.59 Pituitary Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10902805&form=6&db=m Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion. unassigned - 1.2.1.59 Pneumococcal Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28088526&form=6&db=m Subcutaneous immunization with Streptococcus pneumoniae GAPDH confers effective protection in mice via TLR2 and TLR4. diagnostic usage,ongoing research,therapeutic application,unassigned 2,2,1,0 1.2.1.59 Pneumococcal Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29366563&form=6&db=m Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4. causal interaction,unassigned 3,0 1.2.1.59 Pneumonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34133917&form=6&db=m Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 1.2.1.59 Pneumonia, Pneumocystis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19571493&form=6&db=m Evaluation of a real-time PCR assay for the diagnosis of Pneumocystis pneumonia. diagnostic usage,therapeutic application,unassigned 2,2,0 1.2.1.59 Polycystic Kidney Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18923744&form=6&db=m Abnormal glyceraldehyde-3-phosphate dehydrogenase binding and glycolytic flux in Autosomal Dominant Polycystic Kidney Disease after a mild oxidative stress. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Polycystic Kidney Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32543276&form=6&db=m PKD2/polycystin-2 induces autophagy by forming a complex with BECN1. unassigned - 1.2.1.59 Polycystic Kidney, Autosomal Dominant http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18923744&form=6&db=m Abnormal glyceraldehyde-3-phosphate dehydrogenase binding and glycolytic flux in Autosomal Dominant Polycystic Kidney Disease after a mild oxidative stress. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Polycystic Kidney, Autosomal Dominant http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32543276&form=6&db=m PKD2/polycystin-2 induces autophagy by forming a complex with BECN1. unassigned - 1.2.1.59 Porcine Reproductive and Respiratory Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34160254&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity. causal interaction,ongoing research,therapeutic application,unassigned 4,2,2,0 1.2.1.59 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11327094&form=6&db=m Altered mRNA expression of ecNOS and iNOS in myometrium and placenta from women with preeclampsia. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12651901&form=6&db=m Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia. causal interaction,diagnostic usage,unassigned 3,1,0 1.2.1.59 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26105334&form=6&db=m PP011. Increased placental expression of angiogenin inhibitor (Ribonuclease inhibitor), a novel gene in pre-eclampsia. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,1,0 1.2.1.59 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31774373&form=6&db=m LncRNA MALAT1 regulates trophoblast cells migration and invasion via miR-206/IGF-1 axis. diagnostic usage,unassigned 3,0 1.2.1.59 Precursor Cell Lymphoblastic Leukemia-Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11160874&form=6&db=m A novel protein complex distinct from mismatch repair binds thioguanylated DNA. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Prostatic Hyperplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7524903&form=6&db=m Expression of human prostatic acid phosphatase and prostate specific antigen genes in neoplastic and benign tissues. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 1.2.1.59 Prostatic Hyperplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20003831&form=6&db=m DD3(PCA3) gene expression in cancer and prostatic hyperplasia. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Prostatic Hyperplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24512523&form=6&db=m Diagnostic and prognostic scoring system for prostate cancer using urine and plasma biomarkers. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8481901&form=6&db=m Association of glyceraldehyde-3-phosphate dehydrogenase expression with cell motility and metastatic potential of rat prostatic adenocarcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8650074&form=6&db=m There are multiple forms of glyceraldehyde-3-phosphate dehydrogenase in prostate cancer cells and normal prostate tissue. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9826470&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,4 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10407139&form=6&db=m New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase. causal interaction,diagnostic usage,unassigned 3,3,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11205159&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11955624&form=6&db=m Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,4,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12496918&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in late pathological stage human prostate cancer. diagnostic usage,ongoing research,therapeutic application,unassigned 4,4,1,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16326072&form=6&db=m Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,2,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17553795&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18586020&form=6&db=m Expression analysis and clinical utility of L-Dopa decarboxylase (DDC) in prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,1 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18651557&form=6&db=m Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,2,1 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23269617&form=6&db=m Reference gene for primary culture of prostate cancer cells. diagnostic usage,unassigned 4,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25999710&form=6&db=m Effective small interfering RNA delivery in vitro via a new stearylated cationic peptide. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26527100&form=6&db=m The Quantified Level of Circulating Prostate Stem Cell Antigen mRNA relative to GAPDH Level Is a Clinically Significant Indictor for Predicting Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,2,0 1.2.1.59 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28131897&form=6&db=m Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer. causal interaction,therapeutic application,unassigned 2,1,0 1.2.1.59 Proteinuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9175058&form=6&db=m Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,4 1.2.1.59 Proteinuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12087577&form=6&db=m Can glomerular mRNAs in human type 1 diabetes be used to predict transition from normoalbuminuria to microalbuminuria? diagnostic usage,ongoing research,therapeutic application,unassigned 4,2,1,0 1.2.1.59 Psoriasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10721821&form=6&db=m Variation in epidermal housekeeping gene expression in different pathological states. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23277075&form=6&db=m Urban PM2.5 activates GAPDH and induces RBC damage in COPD patients. unassigned - 1.2.1.59 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31996072&form=6&db=m Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers. diagnostic usage,unassigned 1,0 1.2.1.59 Rabies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8411369&form=6&db=m Differential effects of rabies and borna disease viruses on immediate-early- and late-response gene expression in brain tissues. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Rectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33457124&form=6&db=m GAPDH and PUM1: Optimal Housekeeping Genes for Quantitative Polymerase Chain Reaction-Based Analysis of Cancer Stem Cells and Epithelial-Mesenchymal Transition Gene Expression in Rectal Tumors. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 1.2.1.59 Relapsing Fever http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8557349&form=6&db=m A glyceraldehyde-3-phosphate dehydrogenase homolog in Borrelia burgdorferi and Borrelia hermsii. ongoing research,unassigned 2,0 1.2.1.59 Respiratory Distress Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24902773&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice. causal interaction,therapeutic application,unassigned 2,3,0 1.2.1.59 Respiratory Tract Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12668266&form=6&db=m Quantitation of respiratory syncytial virus RNA in nasal aspirates of children by real-time RT-PCR assay. diagnostic usage,ongoing research,unassigned 4,1,0 1.2.1.59 Retinal Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28503176&form=6&db=m Impact of Autoantibodies against Glycolytic Enzymes on Pathogenicity of Autoimmune Retinopathy and Other Autoimmune Disorders. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Retinitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13958738&form=6&db=m [Activity of glyceraldehyde-3-phosphate dehydrogenase in the rabbit retina and in experimental pigmentary retinitis induced by monoiodoacetate. Histochemi-study.] ongoing research,unassigned 1,0 1.2.1.59 Retinitis Pigmentosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19096719&form=6&db=m Evaluation of splicing efficiency in lymphoblastoid cell lines from patients with splicing-factor retinitis pigmentosa. unassigned - 1.2.1.59 Retinitis Pigmentosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32744119&form=6&db=m Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. unassigned - 1.2.1.59 Retinoblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11597600&form=6&db=m Endogenous CRX expression and IRBP promoter activity in retinoblastoma cells. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Sarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19747091&form=6&db=m Molecular characterization of tumor associated glyceraldehyde-3-phosphate dehydrogenase. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,4,0 1.2.1.59 Sarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29950132&form=6&db=m Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. ongoing research,unassigned 1,0 1.2.1.59 Sarcoma, Avian http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16920200&form=6&db=m Urea-nuclease treatment of concentrated retrovirions preserves viral RNA and removes polymerase chain reaction-amplifiable cellular RNA and DNA. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Sarcoma, Ewing http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30410352&form=6&db=m Identification of driver genes associated with chemotherapy resistance of Ewing's sarcoma. therapeutic application,unassigned 1,0 1.2.1.59 Schistosomiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11269278&form=6&db=m Production of interleukin-10 by peripheral blood mononuclear cells from residents of a marshland area in China endemic for Schistosoma japonicum. ongoing research,unassigned 2,0 1.2.1.59 Schistosomiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15463423&form=6&db=m The functional and immunological significance of some schistosome surface molecules. causal interaction,unassigned 1,0 1.2.1.59 Schistosomiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23684788&form=6&db=m Identification of proteins inducing short-lived antibody responses from excreted/secretory products of Schistosoma japonicum adult worms by immunoproteomic analysis. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,2,3,4 1.2.1.59 Schistosomiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33524435&form=6&db=m Structure determination and analyses of the GAPDH from the parasite Schistosoma mansoni, the first one from a platyhelminth. therapeutic application,unassigned 1,0 1.2.1.59 Schistosomiasis japonica http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8406870&form=6&db=m Cloning, molecular characterization, and functional activity of Schistosoma japonicum glyceraldehyde-3-phosphate dehydrogenase, a putative vaccine candidate against schistosomiasis japonica. ongoing research,therapeutic application,unassigned 3,1,0 1.2.1.59 Schistosomiasis japonica http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23684788&form=6&db=m Identification of proteins inducing short-lived antibody responses from excreted/secretory products of Schistosoma japonicum adult worms by immunoproteomic analysis. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,2,3,4 1.2.1.59 Schistosomiasis mansoni http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28346516&form=6&db=m Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase. ongoing research,therapeutic application,unassigned 2,3,0 1.2.1.59 Scoliosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23289769&form=6&db=m Familial or Sporadic Idiopathic Scoliosis - classification based on artificial neural network and GAPDH and ACTB transcription profile. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27816501&form=6&db=m GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 1.2.1.59 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30143487&form=6&db=m Disruption of GluR2/GAPDH Complex Interaction by TAT-GluR2NT1-3-2 Peptide Protects against Neuronal Death Induced by Epilepsy. ongoing research,unassigned 2,0 1.2.1.59 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32717922&form=6&db=m Reference Gene Validation in the Brain Regions of Young Rats after Pentylenetetrazole-Induced Seizures. unassigned - 1.2.1.59 Seminoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15823405&form=6&db=m Standardization strategy for quantitative PCR in human seminoma and normal testis. unassigned - 1.2.1.59 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24858725&form=6&db=m Glyceraldehyde-3-phosphate Dehydrogenase is an Inappropriate Housekeeping Gene for Normalising Gene Expression in Sepsis. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28753256&form=6&db=m A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation. causal interaction,ongoing research,therapeutic application,unassigned 3,3,2,0 1.2.1.59 Severe Acute Respiratory Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15735160&form=6&db=m Development of a quantitative assay for SARS coronavirus and correlation of GAPDH mRNA with SARS coronavirus in clinical specimens. diagnostic usage,unassigned 4,0 1.2.1.59 Shock, Septic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8521087&form=6&db=m [Does nitric oxide stress exist?] causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Shock, Septic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30147344&form=6&db=m Identification of key genes and pathways using bioinformatics analysis in septic shock children. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 1.2.1.59 Skin Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18191230&form=6&db=m Quantitative real-time RT-PCR measurement of cytokine mRNA expression in the skin of normal cats and cats with allergic skin disease. ongoing research,unassigned 3,0 1.2.1.59 Skin Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31811175&form=6&db=m Reference gene screening of Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans for quantitative real-time PCR studies. ongoing research,unassigned 1,0 1.2.1.59 Sleep Apnea, Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33256145&form=6&db=m Redox-Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy. causal interaction,diagnostic usage,therapeutic application,unassigned 2,1,1,0 1.2.1.59 Sleep Deprivation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19445681&form=6&db=m Validation of commonly used reference genes for sleep-related gene expression studies. ongoing research,unassigned 3,0 1.2.1.59 Small Cell Lung Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23988223&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients. causal interaction,diagnostic usage,unassigned 1,1,0 1.2.1.59 Spinal Cord Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30195603&form=6&db=m Inhibiting a spinal cord signaling pathway protects against ischemia injury in rats. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 1.2.1.59 Spinocerebellar Ataxias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8872471&form=6&db=m Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 1.2.1.59 Spinocerebellar Ataxias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9779656&form=6&db=m Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 1.2.1.59 Spinocerebellar Ataxias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30335591&form=6&db=m Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. ongoing research,unassigned 1,0 1.2.1.59 Spondylitis, Ankylosing http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34048311&form=6&db=m MicroRNA let-7i-3p affects osteoblast differentiation in ankylosing spondylitis via targeting PDK1. diagnostic usage,ongoing research,therapeutic application,unassigned 2,2,1,0 1.2.1.59 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12926130&form=6&db=m RT-PCR amplification of RNA extracted from formalin-fixed, paraffin-embedded oral cancer sections: analysis of p53 pathway. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19650912&form=6&db=m Reference gene selection for head and neck squamous cell carcinoma gene expression studies. diagnostic usage,ongoing research,unassigned 3,1,0 1.2.1.59 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22668015&form=6&db=m Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,3 1.2.1.59 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26452026&form=6&db=m High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma. causal interaction,diagnostic usage,unassigned 1,3,0 1.2.1.59 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32944178&form=6&db=m miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas. ongoing research,unassigned 2,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=186035&form=6&db=m Inosine-stimulated insulin release and metabolism of inosine in isolated mouse pancreatic islets. causal interaction,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824452&form=6&db=m Control of glycolysis by glyceraldehyde-3-phosphate dehydrogenase in Streptococcus cremoris and Streptococcus lactis. causal interaction,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7491910&form=6&db=m Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation. unassigned - 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7622588&form=6&db=m Selective induction of cell cycle regulatory genes cdk1 (p34cdc2), cyclins A/B, and the tumor suppressor gene Rb in transformed cells by okadaic acid. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10966377&form=6&db=m Changes in glycolytic activity of Lactococcus lactis induced by low temperature. unassigned - 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12054048&form=6&db=m The Candida albicans cell wall-associated glyceraldehyde-3-phosphate dehydrogenase activity increases in response to starvation and temperature upshift. unassigned - 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12770239&form=6&db=m Metabolic changes in the African fruit beetle, Pachnoda sinuata, during starvation. therapeutic application,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14654434&form=6&db=m Starvation and temperature upshift cause an increase in the enzymatically active cell wall-associated glyceraldehyde-3-phosphate dehydrogenase protein in yeast. ongoing research,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15964159&form=6&db=m Embryotoxicity of the nitric oxide donor sodium nitroprusside in preimplantation bovine embryos in vitro. causal interaction,unassigned 2,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19528073&form=6&db=m Translation inhibition reveals interaction of 2'-deoxy and 2'-O-methyl molecular beacons with mRNA targets in living cells. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21647598&form=6&db=m Increased expression of GAPDH protein is not indicative of nitrosative stress or apoptosis in liver of starved rainbow trout (Oncorhynchus mykiss). causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22570597&form=6&db=m Testing biochemistry revisited: how in vivo metabolism can be understood from in vitro enzyme kinetics. diagnostic usage,ongoing research,unassigned 1,1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25725130&form=6&db=m GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway. causal interaction,unassigned 4,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26626483&form=6&db=m AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation. unassigned - 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26858929&form=6&db=m Effects of prebiotic oligosaccharides consumption on the growth and expression profile of cell surface-associated proteins of a potential probiotic Lactobacillus rhamnosus FSMM15. unassigned - 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28448606&form=6&db=m A feeding protocol for delivery of agents to assess development in Varroa mites. diagnostic usage,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28533178&form=6&db=m Mucin- and carbohydrate-stimulated adhesion and subproteome changes of the probiotic bacterium Lactobacillus acidophilus NCFM. diagnostic usage,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30209366&form=6&db=m GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis. causal interaction,therapeutic application,unassigned 4,2,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30232003&form=6&db=m CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer. causal interaction,ongoing research,therapeutic application,unassigned 4,4,1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30640524&form=6&db=m Trafficking of a multifunctional protein by endosomal micro-autophagy: linking two independent unconventional secretory pathways. unassigned - 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30831195&form=6&db=m Regulation of endothelial cell survival and death by the MAP kinase/ERK kinase kinase 3 - glyceraldehyde-3-phosphate dehydrogenase signaling axis. ongoing research,unassigned 2,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31185291&form=6&db=m Evaluation and validation of experimental condition-specific reference genes for normalization of gene expression in Asia II-I Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae). causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31242129&form=6&db=m MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4. diagnostic usage,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31790793&form=6&db=m GAPDH, rhbC, and vapA gene expression in Rhodococcus equi cultured under different iron concentrations. causal interaction,unassigned 2,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31971848&form=6&db=m Atg11 is required for initiation of glucose starvation-induced autophagy. unassigned - 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32360412&form=6&db=m Screening and evaluation of the stability of expression of reference genes in Lymantria dispar (Lepidoptera: Erebidae) using qRT-PCR. causal interaction,therapeutic application,unassigned 1,1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33319828&form=6&db=m Selection and validation of experimental condition-specific reference genes for qRT-PCR in Metopolophium dirhodum (Walker) (Hemiptera: Aphididae). causal interaction,unassigned 1,0 1.2.1.59 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33758077&form=6&db=m AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer. therapeutic application,unassigned 2,0 1.2.1.59 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19302034&form=6&db=m MYC quantitation in cell-free plasma DNA by real-time PCR for gastric cancer diagnosis. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25081706&form=6&db=m Optimization of reference genes for normalization of the quantitative polymerase chain reaction in tissue samples of gastric cancer. diagnostic usage,ongoing research,therapeutic application,unassigned 1,4,1,0 1.2.1.59 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25785838&form=6&db=m Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNF?-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. diagnostic usage,ongoing research,unassigned 3,3,0 1.2.1.59 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30425814&form=6&db=m Comparative study of gastric cancer and chronic gastritis via network analysis. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32219571&form=6&db=m Identification of novel biomarkers, MUC5AC, MUC1, KRT7, GAPDH, CD44 for gastric cancer. unassigned - 1.2.1.59 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33491552&form=6&db=m Differential regulation of LRRC37A2 in gastric cancer by DNA methylation. diagnostic usage,therapeutic application,unassigned 3,1,0 1.2.1.59 Streptococcal Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9362524&form=6&db=m Regulation of the phosphorylation of human pharyngeal cell proteins by group A streptococcal surface dehydrogenase: signal transduction between streptococci and pharyngeal cells. causal interaction,unassigned 4,0 1.2.1.59 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25882840&form=6&db=m Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. causal interaction,therapeutic application,unassigned 3,1,0 1.2.1.59 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28490769&form=6&db=m Increased cerebral expressions of MMPs, CLDN5, OCLN, ZO1 and AQPs are associated with brain edema following fatal heat stroke. unassigned - 1.2.1.59 Synovitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33258403&form=6&db=m Silencing long non-coding RNA NEAT1 attenuates rheumatoid arthritis via the MAPK/ERK signalling pathway by downregulating microRNA-129 and microRNA-204. diagnostic usage,unassigned 1,0 1.2.1.59 Synucleinopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22134915&form=6&db=m Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in ?-synuclein aggregation. causal interaction,therapeutic application,unassigned 3,3,0 1.2.1.59 Synucleinopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29408361&form=6&db=m Binding of alpha-synuclein to partially oxidized glyceraldehyde-3-phosphate dehydrogenase induces subsequent inactivation of the enzyme. causal interaction,unassigned 1,0 1.2.1.59 Synucleinopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32571190&form=6&db=m ?-Synuclein Overexpression in SH-SY5Y Human Neuroblastoma Cells Leads to the Accumulation of Thioflavin S-positive Aggregates and Impairment of Glycolysis. causal interaction,unassigned 1,0 1.2.1.59 Tauopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18647502&form=6&db=m Identification of non-Alzheimer's disease tauopathies-related proteins by proteomic analysis. unassigned - 1.2.1.59 Tendinopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15138331&form=6&db=m Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies. diagnostic usage,ongoing research,unassigned 3,2,0 1.2.1.59 Teratocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34351536&form=6&db=m In vitro anticancer activity of ethanol extract of Adhatoda vasica Nees on human ovarian cancer cell lines. diagnostic usage,ongoing research,unassigned 1,4,0 1.2.1.59 Testicular Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18489135&form=6&db=m Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells. unassigned - 1.2.1.59 Thrombosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18417195&form=6&db=m Variations in platelet protein associated with arterial thrombosis. causal interaction,unassigned 1,0 1.2.1.59 Thymoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12616366&form=6&db=m Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA levels in thymoma. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,4,0 1.2.1.59 Thymoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27678473&form=6&db=m In vivo and in vitro maturation of rabbit oocytes differently affects the gene expression profile, mitochondrial distribution, apoptosis and early embryo development. ongoing research,unassigned 1,0 1.2.1.59 Thymoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29950132&form=6&db=m Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. ongoing research,unassigned 1,0 1.2.1.59 Thymoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31448672&form=6&db=m PAQR3 suppresses the growth of non-small cell lung cancer cells via modulation of EGFR-mediated autophagy. ongoing research,unassigned 1,0 1.2.1.59 Thyroid Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11437410&form=6&db=m Quantitative measurement of thyroglobulin mRNA in peripheral blood of patients after total thyroidectomy. diagnostic usage,ongoing research,unassigned 4,4,0 1.2.1.59 Thyroid Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17540725&form=6&db=m Involvement of glyceraldehyde-3-phosphate dehydrogenase in tumor necrosis factor-related apoptosis-inducing ligand-mediated death of thyroid cancer cells. causal interaction,ongoing research,therapeutic application,unassigned 1,4,3,0 1.2.1.59 Thyroid Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33035689&form=6&db=m Diagnostic value of circulating cell-free mtDNA in patients with suspected thyroid cancer: ND4/ND1 ratio as a new potential plasma marker. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 1.2.1.59 Toxoplasmosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23026549&form=6&db=m Identification of antigenic proteins of Toxoplasma gondii RH strain recognized by human immunoglobulin G using immunoproteomics. diagnostic usage,unassigned 4,0 1.2.1.59 Triple Negative Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33315498&form=6&db=m Thioridazine hydrochloride: an antipsychotic agent that inhibits tumor growth and lung metastasis in triple-negative breast cancer via inducing G0/G1 arrest and apoptosis. therapeutic application,unassigned 1,0 1.2.1.59 Trypanosomiasis, African http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11063610&form=6&db=m Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine. therapeutic application,unassigned 2,0 1.2.1.59 Trypanosomiasis, African http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19748525&form=6&db=m Genetic validation of aldolase and glyceraldehyde-3-phosphate dehydrogenase as drug targets in Trypanosoma brucei. therapeutic application,unassigned 4,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10702355&form=6&db=m Sequence and characterization of the glyceraldehyde-3-phosphate dehydrogenase of Mycobacterium avium: correlation with an epidermal growth factor binding protein. ongoing research,unassigned 2,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24161676&form=6&db=m Kinetic and mechanistic characterization of the glyceraldehyde 3-phosphate dehydrogenase from Mycobacterium tuberculosis. ongoing research,unassigned 4,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28285168&form=6&db=m Design and use of mouse control DNA for DNA biomarker extraction and PCR detection from urine: Application for transrenal Mycobacterium tuberculosis DNA detection. ongoing research,unassigned 1,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28642848&form=6&db=m Mycobacterium tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Functions as a Receptor for Human Lactoferrin. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30208760&form=6&db=m Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1. unassigned - 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30689890&form=6&db=m Repurposing ethyl bromopyruvate as a broad-spectrum antibacterial. unassigned - 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30710621&form=6&db=m Expression of glyceraldehyde-3-phosphate dehydrogenase from M. tuberculosis in E. coli. Purification and characteristics of the untagged recombinant enzyme. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31760917&form=6&db=m Inhibitors of Glyceraldehyde 3-Phosphate Dehydrogenase and Unexpected Effects of Its Reduced Activity. therapeutic application,unassigned 2,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32079455&form=6&db=m Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block. ongoing research,unassigned 2,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33459133&form=6&db=m Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy. ongoing research,unassigned 2,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33486886&form=6&db=m Mycobacterium tuberculosis glyceraldehyde-3-phosphate dehydrogenase plays a dual role-As an adhesin and as a receptor for plasmin(ogen). therapeutic application,unassigned 3,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34214294&form=6&db=m Discovery of new targeting agents against GAPDH receptor for antituberculosis drug delivery. causal interaction,therapeutic application,unassigned 4,3,0 1.2.1.59 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34341117&form=6&db=m Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity. therapeutic application,unassigned 1,0 1.2.1.59 Ureteral Obstruction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15371768&form=6&db=m Unilateral ureteral obstruction induces renal tubular cell production of tumor necrosis factor-alpha independent of inflammatory cell infiltration. causal interaction,unassigned 4,0 1.2.1.59 Ureteral Obstruction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21565186&form=6&db=m 28S-ribosomal RNA is superior to glyceraldehyde-3-phosphate dehydrogenase as a RNA reference gene in p53-deficient mice with unilateral ureteral obstruction. causal interaction,unassigned 3,0 1.2.1.59 Urinary Bladder Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11113367&form=6&db=m Expression of vascular endothelial growth factor isoforms and platelet-derived endothelial cell growth factor in bladder cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 1.2.1.59 Urinary Bladder Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12165018&form=6&db=m Clinical significance of thymidylate synthase expression in bladder cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,3,0 1.2.1.59 Urinary Bladder Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17060081&form=6&db=m Prognostic significance of homozygous deletions and multiple duplications at the CDKN2A (p16INK4a)/ARF (p14ARF) locus in urinary bladder cancer. diagnostic usage,ongoing research,unassigned 4,2,0 1.2.1.59 Urinary Bladder Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22911551&form=6&db=m Novel insight into the role of GAPDH playing in tumor. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,3 1.2.1.59 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9826470&form=6&db=m Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,4 1.2.1.59 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10645776&form=6&db=m Antisense oligodeoxynucleotide of glyceraldehyde-3-phosphate dehydrogenase gene inhibits cell proliferation and induces apoptosis in human cervical carcinoma cell lines. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,4 1.2.1.59 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18547710&form=6&db=m Expression of RAR beta2 gene by real-time RT-PCR: Differential expression in normal subjects compared to cervical cancer patients normalised against GAPDH as a housekeeping gene. diagnostic usage,ongoing research,unassigned 1,3,0 1.2.1.59 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23060553&form=6&db=m IGF1R gene expression as a predictive marker of response to ionizing radiation for patients with locally advanced HPV16-positive cervical cancer. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Vaccinia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10729139&form=6&db=m Specific phosphorylated forms of glyceraldehyde 3-phosphate dehydrogenase associate with human parainfluenza virus type 3 and inhibit viral transcription in vitro. ongoing research,therapeutic application,unassigned 4,1,0 1.2.1.59 Vaccinia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14515148&form=6&db=m Modulation of GAPDH expression and cellular localization after vaccinia virus infection of human adherent monocytes. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 1.2.1.59 Vesicular Stomatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17488287&form=6&db=m A GAPDH mutant defective in Src-dependent tyrosine phosphorylation impedes Rab2-mediated events. unassigned - 1.2.1.59 Vibrio Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17953570&form=6&db=m Characterization of OmpK, GAPDH and their fusion OmpK-GAPDH derived from Vibrio harveyi outer membrane proteins: their immunoprotective ability against vibriosis in large yellow croaker (Pseudosciaena crocea). ongoing research,therapeutic application,unassigned 3,2,0 1.2.1.59 Vibrio Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26344624&form=6&db=m Pleurocidin Peptide Enhances Grouper Anti-Vibrio harveyi Immunity Elicited by Poly(lactide-co-glycolide)-Encapsulated Recombinant Glyceraldehyde-3-phosphate Dehydrogenase. therapeutic application,unassigned 3,0 1.2.1.59 Viremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18799222&form=6&db=m CD4+CD25+ regulatory T cells are infected and activated during acute FIV infection. diagnostic usage,ongoing research,unassigned 4,3,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8411369&form=6&db=m Differential effects of rabies and borna disease viruses on immediate-early- and late-response gene expression in brain tissues. causal interaction,diagnostic usage,unassigned 2,3,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14515148&form=6&db=m Modulation of GAPDH expression and cellular localization after vaccinia virus infection of human adherent monocytes. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15081603&form=6&db=m Real time PCR for monitoring regulation of host gene expression in herpes simplex virus type 1-infected human diploid cells. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,3,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18692141&form=6&db=m Differential modulations of two glyceraldehyde 3-phosphate dehydrogenase mRNAs in response to bacterial and viral challenges in a marine teleost Oplegnathus fasciatus (Perciformes). ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19580983&form=6&db=m Host cell proteins interacting with the 3' end of TGEV coronavirus genome influence virus replication. therapeutic application,unassigned 3,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21053249&form=6&db=m Using host 28S ribosomal RNA as a housekeeping gene for quantitative real-time reverse transcription-PCR (qRT-PCR) in virus-infected animal cells. ongoing research,unassigned 2,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21925148&form=6&db=m Systematic selection of housekeeping genes for gene expression normalization in chicken embryo fibroblasts infected with Newcastle disease virus. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,2,1 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23043930&form=6&db=m 18S rRNA is a reliable normalisation gene for real time PCR based on influenza virus infected cells. ongoing research,unassigned 3,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23994079&form=6&db=m Assessment of reference gene stability influenced by extremely divergent disease symptoms in Solanum lycopersicum L. ongoing research,unassigned 1,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28232024&form=6&db=m Selection and validation of candidate reference genes for quantitative real-time PCR studies in the shrimp Penaeus vannamei under viral infection. ongoing research,therapeutic application,unassigned 2,1,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28548037&form=6&db=m Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30071880&form=6&db=m Endogenous gene selection for relative quantification PCR and IL6 transcript levels in the PBMC's of severe and non-severe dengue cases. diagnostic usage,ongoing research,therapeutic application,unassigned 1,3,1,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33185982&form=6&db=m Interferon-stimulated gene products as regulators of central carbon metabolism. causal interaction,therapeutic application,unassigned 4,1,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34160254&form=6&db=m Glyceraldehyde-3-Phosphate Dehydrogenase Restricted in Cytoplasmic Location by Viral GP5 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication via Its Glycolytic Activity. causal interaction,ongoing research,therapeutic application,unassigned 4,2,2,0 1.2.1.59 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34313529&form=6&db=m Rice black-streaked dwarf virus P10 promotes phosphorylation of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) to induce autophagy in Laodelphax striatellus. causal interaction,therapeutic application,unassigned 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