1.1.1.53 11beta-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12649576&form=6&db=m 11beta-hydroxysteroid dehydrogenase type 1 deficiency ('apparent cortisone reductase deficiency') in a 6-year-old boy. causal interaction,ongoing research,unassigned 3,1,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8370690&form=6&db=m Defects in the HSD11 gene encoding 11 beta-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8923828&form=6&db=m Apparent cortisone reductase deficiency: a unique form of hypercortisolism. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10522997&form=6&db=m Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11150889&form=6&db=m Apparent cortisone reductase deficiency: a rare cause of hyperandrogenemia and hypercortisolism. causal interaction,therapeutic application,unassigned 4,1,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11469811&form=6&db=m Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12858176&form=6&db=m Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. causal interaction,unassigned 2,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15315958&form=6&db=m 11{beta}-Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid Response. causal interaction,therapeutic application,unassigned 3,2,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15466942&form=6&db=m 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. causal interaction,therapeutic application,unassigned 3,2,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15827106&form=6&db=m A study of the hexose-6-phosphate dehydrogenase gene R453Q and 11beta-hydroxysteroid dehydrogenase type 1 gene 83557insA polymorphisms in the polycystic ovary syndrome. ongoing research,unassigned 2,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15956339&form=6&db=m Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16091483&form=6&db=m Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample. causal interaction,unassigned 3,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16551740&form=6&db=m Genetic variation in 11beta-hydroxysteroid dehydrogenase type 1 predicts adrenal hyperandrogenism among lean women with polycystic ovary syndrome. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,2 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16817821&form=6&db=m Variants implicated in cortisone reductase deficiency do not contribute to susceptibility to common forms of polycystic ovary syndrome. unassigned - 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17062770&form=6&db=m Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia. causal interaction,ongoing research,therapeutic application,unassigned 3,2,1,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17240046&form=6&db=m Hexose 6-phosphate dehydrogenase (H6PD) and corticosteroid metabolism. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17368420&form=6&db=m [11beta-hydroxysteroide dehydrogenases. Recent advances] causal interaction,diagnostic usage,therapeutic application,unassigned 4,1,4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18622204&form=6&db=m Physiological roles of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase. causal interaction,ongoing research,unassigned 4,4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18628520&form=6&db=m Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19935835&form=6&db=m Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis. causal interaction,therapeutic application,unassigned 3,4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20417277&form=6&db=m Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS). causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21050867&form=6&db=m Mutations of the hexose-6-phosphate dehydrogenase gene rarely cause hyperandrogenemic polycystic ovary syndrome. causal interaction,unassigned 3,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21325058&form=6&db=m Cortisone-reductase deficiency associated with heterozygous mutations in 11{beta}-hydroxysteroid dehydrogenase type 1. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21622478&form=6&db=m Premature adrenarche: novel lessons from early onset androgen excess. causal interaction,therapeutic application,unassigned 4,1,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21874273&form=6&db=m Role of a Disordered Steroid Metabolome in the Elucidation of Sterol and Steroid Biosynthesis. causal interaction,therapeutic application,unassigned 3,1,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22238371&form=6&db=m Association Study of CYP17 and HSD11B1 in Polycystic Ovary Syndrome Utilizing Comprehensive Gene Coverage. causal interaction,ongoing research,unassigned 4,2,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23132696&form=6&db=m Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23612224&form=6&db=m 11?-hydroxysteroid dehydrogenase 1: translational and therapeutic aspects. diagnostic usage,ongoing research,unassigned 3,2,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25096886&form=6&db=m Novel insight into etiology, diagnosis and management of primary adrenal insufficiency. causal interaction,unassigned 4,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26297192&form=6&db=m Estimation of reference curves for the urinary steroid metabolome in the first year of life in healthy children: Tracing the complexity of human postnatal steroidogenesis. therapeutic application,unassigned 1,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29073307&form=6&db=m A follow-up history of young man with apparent cortisone reductase deficiency (ACRD) - several years after diagnosis. causal interaction,diagnostic usage,therapeutic application,unassigned 4,2,1,0 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29843121&form=6&db=m Alterations of Cortisol Metabolism in Human Disorders. causal interaction,unassigned 3,0 1.1.1.53 Cushing Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8923828&form=6&db=m Apparent cortisone reductase deficiency: a unique form of hypercortisolism. causal interaction,unassigned 4,0 1.1.1.53 Cushing Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11150889&form=6&db=m Apparent cortisone reductase deficiency: a rare cause of hyperandrogenemia and hypercortisolism. causal interaction,therapeutic application,unassigned 4,1,0 1.1.1.53 Hyperandrogenism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16551740&form=6&db=m Genetic variation in 11beta-hydroxysteroid dehydrogenase type 1 predicts adrenal hyperandrogenism among lean women with polycystic ovary syndrome. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,2 1.1.1.53 Hyperandrogenism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17240046&form=6&db=m Hexose 6-phosphate dehydrogenase (H6PD) and corticosteroid metabolism. causal interaction,unassigned 4,0 1.1.1.53 Hyperandrogenism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21050867&form=6&db=m Mutations of the hexose-6-phosphate dehydrogenase gene rarely cause hyperandrogenemic polycystic ovary syndrome. causal interaction,unassigned 3,0 1.1.1.53 Hyperandrogenism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29843121&form=6&db=m Alterations of Cortisol Metabolism in Human Disorders. causal interaction,unassigned 3,0 1.1.1.53 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11469811&form=6&db=m Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase. causal interaction,unassigned 4,0 1.1.1.53 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11469811&form=6&db=m Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase. causal interaction,unassigned 4,0 1.1.1.53 nadph-hemoprotein reductase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20417277&form=6&db=m Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS). causal interaction,unassigned 4,0 1.1.1.53 nadph-hemoprotein reductase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21874273&form=6&db=m Role of a Disordered Steroid Metabolome in the Elucidation of Sterol and Steroid Biosynthesis. causal interaction,therapeutic application,unassigned 3,1,0 1.1.1.53 nadph-hemoprotein reductase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25096886&form=6&db=m Novel insight into etiology, diagnosis and management of primary adrenal insufficiency. causal interaction,unassigned 4,0 1.1.1.53 nadph-hemoprotein reductase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26297192&form=6&db=m Estimation of reference curves for the urinary steroid metabolome in the first year of life in healthy children: Tracing the complexity of human postnatal steroidogenesis. therapeutic application,unassigned 1,0 1.1.1.53 Polycystic Ovary Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12858176&form=6&db=m Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. causal interaction,unassigned 2,0 1.1.1.53 Polycystic Ovary Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15827106&form=6&db=m A study of the hexose-6-phosphate dehydrogenase gene R453Q and 11beta-hydroxysteroid dehydrogenase type 1 gene 83557insA polymorphisms in the polycystic ovary syndrome. ongoing research,unassigned 2,0 1.1.1.53 Polycystic Ovary Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16817821&form=6&db=m Variants implicated in cortisone reductase deficiency do not contribute to susceptibility to common forms of polycystic ovary syndrome. unassigned - 1.1.1.53 Polycystic Ovary Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21050867&form=6&db=m Mutations of the hexose-6-phosphate dehydrogenase gene rarely cause hyperandrogenemic polycystic ovary syndrome. causal interaction,unassigned 3,0 1.1.1.53 steroid sulfotransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21622478&form=6&db=m Premature adrenarche: novel lessons from early onset androgen excess. causal interaction,therapeutic application,unassigned 4,1,0