3.4.23.47	analysis of 19 ligand-bound wild-type enzyme crystal structures, overview. Mutation K57L is experimentally introduced in 8 structures to help the crystallographic process	
3.4.23.47	crystallized by hanging drop method in complex with a reduced amide inhibitor, BI-LA-398	
3.4.23.47	crystals grown by hanging-drop vapor diffusion method, thin tetragonal prisms, space group P4(1)2(1)2 or P4(3)2(1)2 with a=b=62.6 A and c=115.8 A	
3.4.23.47	in complex with inhibitor amprenavir, to 1.5 A resolution, and comparison with HIV-1 protease PR1M	
3.4.23.47	molecular dynamics simulations in complerx with inhibitors amprenvir and darunavir	
3.4.23.47	monoclinic crystals, vapor diffusion, hanging drops, P2(1) space group with a =36.76 A, b=58.44 A, c= 55.11 A and beta=91.20°	
3.4.23.47	Phe-Val-Phe-psi-CH2NH-Leu-Glu-Ile-amide, space group P4(1) or P4(3), unit-cell parameters a=b=55.1 A, c=138.9 A	
3.4.23.47	substrate binding pocket structure analysis