2.3.1.282 homology modeling and docking of modeled mycocerosic acid synthase docked on the structure of PapA5 2.3.1.282 to 2.75 A resoultion. The PapA5 active site includes conserved histidine and aspartic acid residues that are critical to PapA5 acyltransferase activity. Two hydrophobic channels link the PapA5 surface to the active. An additional alpha helix blocks the putative entrance into the PapA5 active site