2.5.1.6 additional information - additional information Ki values for several phosphonate analogues and nucleotides 639050, 639051 2.5.1.6 0.000002 - diimidotriphosphate pH 8.0 658062 2.5.1.6 0.0031 - L-2-Amino-4-methoxy-cis-but-3-enoic acid isoenzyme II 639047 2.5.1.6 0.0057 - L-2-Amino-4-methylthio-cis-but-3-enoic acid isoenzyme II 639047 2.5.1.6 0.0063 - L-2-Amino-4-methoxy-cis-but-3-enoic acid isoenzyme I 639047 2.5.1.6 0.02 - S-adenosyl-L-methionine 37°C, pH 8.0, wild-type enzyme 759009 2.5.1.6 0.021 - L-2-Amino-4-methylthio-cis-but-3-enoic acid isoenzyme I 639047 2.5.1.6 0.035 - tripolyphosphate - 639063 2.5.1.6 0.05 - S-adenosylmethionine inhibits the A isoform 639048 2.5.1.6 0.05 - S-adenosylmethionine S-adenosylmethionine synthetase A 639048 2.5.1.6 0.05 - tripolyphosphate - 639050 2.5.1.6 0.12 - S-adenosyl-L-methionine 37°C, pH 8.0, mutant enzyme I303V 759009 2.5.1.6 0.18 - Tetrapolyphosphate - 639050 2.5.1.6 0.2 - tripolyphosphate inhibition with respect to L-methionine 639075 2.5.1.6 0.24 - S-adenosylmethionine - 639046 2.5.1.6 0.25 - tripolyphosphate inhibition with respect to ATP 639075 2.5.1.6 0.3 - diphosphate inhibition with respect to ATP 639075 2.5.1.6 0.35 - diphosphate inhibition with respect to L-methionine 639075 2.5.1.6 0.4 - D-methionine - 639046 2.5.1.6 0.51 - seleno-L-methionine - 639046 2.5.1.6 0.71 - DL-Ethionine - 639046 2.5.1.6 0.8 - ATP noncompetitive inhibition at 0.5-5 mM ATP concentrations 639075 2.5.1.6 0.8 - S-adenosylmethionine ATP concentrations of 0.5-5 mM 639078 2.5.1.6 1.6 - Sodium diphosphate - 639046 2.5.1.6 3.6 - cycloleucine pH 8.2, 37°C 658771 2.5.1.6 3.7 - Azathioprine 37°C, pH 8.2 658351 2.5.1.6 4 - S-adenosylmethionine L-methionine concentrations of 0.5-5 mM 639078 2.5.1.6 4 - S-adenosylmethionine noncompetitive inhibition at 0.5-5 mM L-methionine concentrations 639075 2.5.1.6 4.7 - 8-Azaguanine 37°C, pH 8.2 658351 2.5.1.6 17 - cycloleucine - 639046 2.5.1.6 250 - Na+ in presence of Mg2+ 639046