1.7.3.3 additional information - additional information 1-methylurate, 3-methylurate, 7-methylurate do not inhibit significantly 394180 1.7.3.3 0.00035 - oxonate mutant enzyme V144A/Y319R, at pH 7.4 and 25°C 765718 1.7.3.3 0.00042 - oxonate mutant enzyme Y319R, at pH 7.4 and 25°C 765718 1.7.3.3 0.00045 - oxonate mutant enzyme V144A, at pH 7.4 and 25°C 765718 1.7.3.3 0.00052 - oxonate wild type enzyme, at pH 7.4 and 25°C 765718 1.7.3.3 0.0021 - 8-nitroxanthine competitive inhibitor versus urate at pH 8.0 671971 1.7.3.3 0.0042 - oxonate mutant enzyme Y319R, at pH 9.2 and 25°C 765718 1.7.3.3 0.0049 - oxonate mutant enzyme V144A, at pH 9.2 and 25°C 765718 1.7.3.3 0.0049 - oxonate mutant enzyme V144A/Y319R, at pH 9.2 and 25°C 765718 1.7.3.3 0.0056 - oxonate wild type enzyme, at pH 9.2 and 25°C 765718 1.7.3.3 0.008 - oxonate unmodified enzyme, 50 mM borate buffer, 25°C, pH 9.2 711515 1.7.3.3 0.041 - xanthine more than 0.03 mM 672697 1.7.3.3 0.055 - xanthine unmodified enzyme, 50 mM borate buffer, 25°C, pH 9.2 711515 1.7.3.3 0.1 - xanthine unmodified enzyme, 50 mM borate buffer, 40°C, pH 9.2 711515 1.7.3.3 4.5 - xanthine competitive with urate 394180