1.1.1.267 additional information - additional information inhibition kinetics 673073 1.1.1.267 0.0000019 - [3-[acetyl(hydroxy)amino]-1-(pyridin-3-yl)propyl]phosphonic acid pH 7.5, 22°C 723812 1.1.1.267 0.000002 - phosphoric acid mono-[2-(N-acetyl-N-hydroxy-amino)-ethyl]-ester pH 7.5, 37°C 672538 1.1.1.267 0.0000021 - fosmidomycin - 675580 1.1.1.267 0.0000089 - [3-[formyl(hydroxy)amino]-1-(pyridin-4-yl)propyl]phosphonic acid pH 7.5, 22°C 723812 1.1.1.267 0.000013 - [3-[acetyl(hydroxy)amino]-1-(pyridin-4-yl)propyl]phosphonic acid pH 7.5, 22°C 723812 1.1.1.267 0.000013 - [3-[formyl(hydroxy)amino]-1-(pyridin-3-yl)propyl]phosphonic acid pH 7.5, 22°C 723812 1.1.1.267 0.000014 - fosmidomycin mutant W203Y, pH 7.5, 25°C 740062 1.1.1.267 0.000019 - fosfoxacin pH 7.5, 37°C 672538 1.1.1.267 0.000021 - fosmidomycin pH 7.5, 22°C 723812 1.1.1.267 0.000034 - fosmidomycin pH 7.5, 22°C, IC50 versus proliferation of Plasmodium falciparum strain Dd2 723812 1.1.1.267 0.000035 - [3-[formyl(hydroxy)amino]-1-(pyridin-4-yl)propyl]phosphonic acid pH 7.5, 22°C, IC50 versus proliferation of Plasmodium falciparum strain Dd4 723812 1.1.1.267 0.000042 - [3-[acetyl(hydroxy)amino]-1-(pyridin-3-yl)propyl]phosphonic acid pH 7.5, 22°C, IC50 versus proliferation of Plasmodium falciparum strain Dd5 723812 1.1.1.267 0.000048 - FR900098 pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.000055 - [3-[formyl(hydroxy)amino]-1-(pyridin-3-yl)propyl]phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.000057 - fosmidomycin pH 7.5, 37°C 672538 1.1.1.267 0.00006 - fosmidomycin mutant W203F, pH 7.5, 25°C 740062 1.1.1.267 0.000077 - [1-(3,4-dichlorophenyl)-3-[formyl(hydroxy)amino]propyl]phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.000079 - [3-[formyl(hydroxy)amino]-1-(pyridin-4-yl)propyl]phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.000082 - [3-[acetyl(hydroxy)amino]-1-(pyridin-4-yl)propyl]phosphonic acid pH 7.5, 22°C, IC50 versus proliferation of Plasmodium falciparum strain Dd6 723812 1.1.1.267 0.000085 - fosmidomycin pH 8.0, 37°C, recombinant pseudomature enzyme 673562 1.1.1.267 0.000085 - [3-[acetyl(hydroxy)amino]-1-phenylpropyl]phosphonic acid pH 7.5, 22°C 723812 1.1.1.267 0.000087 - [3-[formyl(hydroxy)amino]-1-(pyridin-3-yl)propyl]phosphonic acid pH 7.5, 22°C, IC50 versus proliferation of Plasmodium falciparum strain Dd3 723812 1.1.1.267 0.00009 - fosmidomycin pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.000093 - fosmidomycin wild-type, pH 7.5, 25°C 740062 1.1.1.267 0.0000989 - fosmidomycin pH 7.8, 22°C 713353 1.1.1.267 0.00017 - FR900098 pH 7.8, 37°C 741292 1.1.1.267 0.00022 - [3-[acetyl(hydroxy)amino]-1-(3,4-dichlorophenyl)propyl]phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.00048 - [3-[formyl(hydroxy)amino]-1-phenylpropyl]phosphonic acid pH 7.5, 22°C 723812 1.1.1.267 0.00053 - [3-[acetyl(hydroxy)amino]-1-(pyridin-4-yl)propyl]phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.0009 - FR900098 pH 7.5, 37°C 672538 1.1.1.267 0.00093 - [3-[acetyl(hydroxy)amino]-1-phenylpropyl]phosphonic acid pH 7.5, 22°C, IC50 versus proliferation of Plasmodium falciparum strain Dd8 723812 1.1.1.267 0.00097 - fosmidomycin pH 7.8, 37°C 741292 1.1.1.267 0.00097 - [3-[acetyl(hydroxy)amino]-1-(pyridin-3-yl)propyl]phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.0014 - 1-hydroxy-5-phenylpyridin-2(1H)-one pH not specified in the publication, temperature not specified in the publication 712689 1.1.1.267 0.0015 - [3-[formyl(hydroxy)amino]-1-phenylpropyl]phosphonic acid pH 7.5, 22°C, IC50 versus proliferation of Plasmodium falciparum strain Dd7 723812 1.1.1.267 0.0021 - [(5-phenylpyridin-2-yl)methyl]phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.0041 - (pyridin-2-ylmethyl)phosphonic acid pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.0133 - theaflavin-3,3'-digallate substrate 1-deoxy-D-xylulose 5-phosphate, pH 7.4, 37°C 741430 1.1.1.267 0.0182 - theaflavin-3,3'-digallate substrate NADPH, pH 7.4, 37°C 741430 1.1.1.267 0.0222 - theaflavin-3'-gallate substrate 1-deoxy-D-xylulose 5-phosphate, pH 7.4, 37°C 741430 1.1.1.267 0.0224 - 4-benzylbenzene-1,2-diol pH not specified in the publication, temperature not specified in the publication 712689 1.1.1.267 0.0224 - theaflavin-3'-gallate substrate NADPH, pH 7.4, 37°C 741430 1.1.1.267 0.0234 - gallocatechin gallate pH 7.0, 37°C, recombinant enzyme, uncompetitive versus NADPH 762667 1.1.1.267 0.0247 - theaflavin-3-gallate substrate NADPH, pH 7.4, 37°C 741430 1.1.1.267 0.0252 - gallocatechin gallate pH 7.0, 37°C, recombinant enzyme, competitive versus 1-deoxy-D-xylulose 5-phosphate 762667 1.1.1.267 0.0256 - 1-hydroxy-5-phenylpyridin-2(1H)-one pH 7.6, 30°C, recombinant enzyme 724543 1.1.1.267 0.03 - theaflavin-3-gallate substrate 1-deoxy-D-xylulose 5-phosphate , pH 7.4, 37°C 741430 1.1.1.267 0.0447 - biphenyl-3,4-diol pH not specified in the publication, temperature not specified in the publication 712689 1.1.1.267 0.1483 - epigallocatechin gallate pH 7.0, 37°C, recombinant enzyme, competitive versus 1-deoxy-D-xylulose 5-phosphate 762667 1.1.1.267 0.1794 - epigallocatechin gallate pH 7.0, 37°C, recombinant enzyme, uncompetitive versus NADPH 762667 1.1.1.267 0.24 - 4-(N-formyl-N-hydroxy-amino)-butyric acid pH 7.5, 37°C 672538 1.1.1.267 0.444 - 3-fluoro-1-deoxy-D-xylulose-5-phosphate - 656890 1.1.1.267 0.63 - 1,2-dideoxy-D-threo-3-hexulose 6-phosphate pH 7.8, 37°C, recombinant wild-type enzyme 671590 1.1.1.267 0.733 - 4-fluoro-1-deoxy-D-xylulose-5-phosphate - 656890 1.1.1.267 1.1 - 1-deoxy-D-xylulose 5-phosphate pH 7.9, 30°C, recombinant His-tagged enzyme 674260 1.1.1.267 2 - 1,1,1-trifluoro-1-deoxy-D-xylulose 5-phosphoric acid pH 7.6, 37°C, recombinant enzyme 675577 1.1.1.267 2.4 - [4-(hydroxyamino)-4-oxobutyl]phosphonic acid pH 7.5, 37°C 672538 1.1.1.267 2.8 - sulfamic acid 2-(N-formyl-N-hydroxy-amino)-ethyl ester pH 7.5, 37°C 672538 1.1.1.267 3.4 - 1,1-difluoro-1-deoxy-D-xylulose 5-phosphoric acid pH 7.6, 37°C, recombinant enzyme 675577 1.1.1.267 3.6 - [3-(N-acetyl-N-methyl-amino)propyl]-phosphonic acid pH 7.5, 37°C 672538 1.1.1.267 5 - [3-(N-formyl-N-methyl-amino)-propyl]-phosphonic acid pH 7.5, 37°C 672538 1.1.1.267 6.2 - 1,2-dideoxy-D-hexulose 6-phosphate pH 7.6, 37°C, recombinant enzyme 675577 1.1.1.267 6.5 - (3-acetamidopropyl)phosphonic acid pH and temperature not specified in the publication 763000