4.2.1.45 NAD+ - 33864 4.2.1.45 NAD+ catalytic prosthetic group, NAD+ serves as a hydride carrier receiving the 4H of the substrate in the oxidative half-reaction and passing the reducing equivalents to C-6 in the reductive half-reaction, the substrate is bound to the si-face of the nicotinamide ring 33861 4.2.1.45 NAD+ dependent 649191, 650244 4.2.1.45 NAD+ required 33857, 33858 4.2.1.45 NAD+ two binding sites per enzyme molecule 33859 4.2.1.45 NADP+ 20% of the activity with NAD+ 33864