3.5.1.98 ATP required for deacetylation of histone H4 in purified nucleosomes by isoforms HDAC1 and HDAC3. ATP also enhances cleavage of free, non-nucleosomal histones by HDAC1 and HDAC3 680623 3.5.1.98 additional information deacetylation by isoform dHDAC1 does not require any additional cofactors 680614 3.5.1.98 NAD+ - 711880