2.1.1.201 NADH NAFH is required form optimal activity in in vitro assay with mitochondrial lysate. It is likely that the function of NADH is the reduction of the oxidized 2-methoxy-6-polyprenyl-1,4-benzoquinone substrate to the hydroquinone form (2-methoxy-6-polyprenyl-1,4-benzoquinol), which presumably acts as the methyl acceptor 704388 2.1.1.201 S-adenosyl-L-methionine - 735364