1.1.1.202	additional information	NADP+ has no coenzyme activity	389488	
1.1.1.202	additional information	no cofactor: NADPH	721395	
1.1.1.202	additional information	PDOR requires NAD(H) as a cofactor, but the highly conserved NAD(H) binding fingerprint pattern G-X-G-X-X-G is not present in the amino acid sequence	740927	
1.1.1.202	NAD+	-	389488, 389490, 655107, 657320, 657406, 670216, 675901, 684171, 684524, 688171, 698602, 721395, 724566, 725951, 740214, 740216, 740927, 760717	
1.1.1.202	NAD+	the enzyme contains a cofactor motif, the conserved sequence G-GG-S-X-X-D. The binding site for cofactor NAD(H) is located in the deep hydrophilic pocket between the PDOR two domains	739886	
1.1.1.202	NADH	-	389488, 389490, 655107, 657406, 664422, 667270, 670216, 675901, 684171, 684524, 688171, 695842, 696785, 699149, 699357, 721395, 724566, 725951, 739886, 740214, 740216, 740927, 761555	
1.1.1.202	NADH	overexpression of PDOR leads to enhanced NADH and production ratio of NADH/NAD+ exceeds after the inducement of isopropyl-beta-D-thiogalactoside for the constructed strain	697666	
1.1.1.202	NADH	the electrostatic energy is the major force discriminating NADH from NADPH. Residue Asp41 is the key residue responsible for the coenzyme specificity	712531	
1.1.1.202	NADH	the enzyme prefers NADH to NAD+ as cofactor. 0.5 mM NADH is chosen as optimum concentration	760717	
1.1.1.202	NADPH	-	695764, 695844