1.1.1.145 additional information no reaction with 3-acetylpyridine-adenine dinucleotide, nicotinamide-hypoxanthine dinucleotide, 3-acetylpyridine-hypoxanthine dinucleotide 389376 1.1.1.145 additional information no significant activity with NAD+/NADH 684725 1.1.1.145 NAD+ - 2884, 2898, 389370, 389371, 389373, 389374, 389376, 389378, 389379, 389380, 389382, 389383, 389384, 389385, 389386, 389387, 389388, 389389, 389390, 389391, 389392, 389393, 389395, 389396, 389397, 389399, 389400, 389401, 389402, 656091, 656652, 656655, 662371, 667452, 668423, 670036, 670037, 693887, 699845, 700182, 700557, 740503, 740914, 740998, 741250, 741261, 741423, 763397 1.1.1.145 NAD+ cysteinyl and histidyl at NAD+-binding site 389369 1.1.1.145 NAD+ more than 10fold as active as NADP+ 389372 1.1.1.145 NAD+ NADH forms hydrogen bond with Asp35 in the NADH-wild-type 3beta-HSD1 complex 725612 1.1.1.145 NAD+ optimum coenzyme concentration is 1.5 mmol/l 763139 1.1.1.145 NAD+ preferred 389377 1.1.1.145 NADH - 662371, 669061, 699111 1.1.1.145 NADP+ - 389371, 389378, 389402, 684725