1.14.14.16 cytochrome P450 - 659747, 698536, 698864, 699170, 699173 1.14.14.16 cytochrome P450 Cyp21 is a cytochrome P450 monooxygenase 715690 1.14.14.16 cytochrome P450S21 steroid 21-hydroxylase system consists of cytochrome P-450S21, NADPH-cytochrome P-450 reductase (EC 1.6.2.4) and steroid 21-monooxygenase (EC 1.14.99.10) 285440 1.14.14.16 heme - 726962, 727898, 728691 1.14.14.16 heme 0.8 mol/mol peptide 285446 1.14.14.16 NADH - 658359, 658562, 659747 1.14.14.16 NADH NADH is 50% as effective as NADPH 285439 1.14.14.16 NADPH - 285439, 698190, 698536, 698864 1.14.14.16 NADPH the redox cofactor provides the electrons required for a P450-dependent hydroxylation 715690