7.2.2.19 6.5 8.5 at pH 6.5 30% and at pH 8.5 less than 1% of all binding sites are occupied by H+ ions 672636 7.2.2.19 6.8 7.8 pH 6.8: about 60% of maximal activity, pH 7.8: about 45% of maximal activity 246853