3.2.1.18 3 5.8 - 171134 3.2.1.18 3 6 - 171112 3.2.1.18 3 6 pH 3.0: about 65% of maximal activity, pH 6.0: about 50% of maximal activity, sialidase isoenzyme NA1 665425 3.2.1.18 3.5 5 pH 3.5: about 30% of maximal activity, pH 5.0: about 60% of maximal activity 666315 3.2.1.18 3.5 5.5 - 171164 3.2.1.18 3.5 6.5 pH 3.5: about 55% of maximal activity, pH 6.5: about 55% of maximal activity, sialidase isoenzyme NA2 665425 3.2.1.18 4 6 - 171182 3.2.1.18 4 6.8 - 655754 3.2.1.18 4 7.5 - 171185 3.2.1.18 4 8 - 171167 3.2.1.18 4 8.5 complete cessation of activity at pH 4 and 8.5 664546 3.2.1.18 4 9 - 171180, 655830 3.2.1.18 4 9 isoform Am0707 shows considerable enzymatic activity between pH 4.0 and 9.0 750235 3.2.1.18 4 11 - 171149 3.2.1.18 4.5 6 - 171135, 171150 3.2.1.18 4.5 6.5 activity range, almost inactive at pH 4.0 and pH 7.0 718101 3.2.1.18 4.5 7.5 - 171184 3.2.1.18 4.5 8 - 171173 3.2.1.18 5 9 - 171177 3.2.1.18 5.5 9 - 655830 3.2.1.18 6 8 more than 70% of activity is maintained from pH 6.0 to 8.0 729295 3.2.1.18 6 9.5 - 655779 3.2.1.18 8 - the enzyme shows broad pH specificity of sialidase activity even at neutral and alkaline pH with 30% activity remaining at pH 8.0 729760 3.2.1.18 9 - at pH 9.0, the activity of all three sialidase isoforms has decreased by about 50% 729041