1.7.3.3 6 - more than 80% of maximum activity 743735 1.7.3.3 6 9 the enzyme is mostly active over a broad pH range of 6.0 to 9.0 764830 1.7.3.3 6 11 the enzyme activity remains stable after 15 min at pH 6.0-11.0 (4, 25 and 37°C) 763780 1.7.3.3 6.5 9.5 free uricase shows at least 50% relative activity between pH 6.5 and 9.5, around pH 7.5, free uricase remains 81.16% of its maximum activity, while the uricase loaded in the lipid vesicles remains almost the same high activity (178.26%) as its optimum activity (179.72%) 712197 1.7.3.3 6.5 11 pH 6.5: about 40% of maximal activity, pH 10.0: about 50% of maximal activity 701416 1.7.3.3 7 11 more than 50% activity between pH 7.0 and 11.0 764897 1.7.3.3 7 11 pH 7: about 50% of activity maximum, pH 11: about 40% of activity maximum 394146 1.7.3.3 7.4 9.6 50% of activity maximum at pH 7.4 and pH 9.6, free enzyme 394156 1.7.3.3 7.5 8.5 - 712513 1.7.3.3 8 9 - 394190 1.7.3.3 8 10.2 pH 8.0: about 35% of activity maximum, pH 10.2: about 55% of activity maximum 394141 1.7.3.3 8 11 50% of activity maximum at pH 8 and pH 11, immobilized enzyme 394156 1.7.3.3 8.5 9.1 - 394190 1.7.3.3 8.5 9.5 - 394182 1.7.3.3 8.5 10.5 50% of activity maximum at pH 8.5 and pH 10.5 394150 1.7.3.3 8.6 9.5 - 394190 1.7.3.3 9 - more than 80% of maximum activity 743735 1.7.3.3 9 9.7 - 394190 1.7.3.3 9 10.5 - 672697