3.2.1.46	-	
3.2.1.46	a specific neurologically relevant murine cell-line (145M-Twi) is modified to express common human hGALC-G270D mutant	
3.2.1.46	expression in CHO cells	
3.2.1.46	expression in lentiviral GALC vectors	
3.2.1.46	expression vectors for different fusion-proteins are constructed: GALC, unmodified enzyme, GALC-MH: fusion protein containing a C-terminal myc-tag and six His residues, GALC-TMH: fusion protein containing in addition a Tat-PTD, the protein transduction domain derived from the HIV-1 Tat protein	
3.2.1.46	exression in lentiviral GALC vectors	
3.2.1.46	mutation in Krabbe disease	
3.2.1.46	Newborn screening for Krabbe's disease, several variants in confirmed patients are identified. In some cases, polymorphisms is seen in cis with these variants. These variants are expressed in COS1 cells	
3.2.1.46	nonsense mutation in Krabbe disease