3.2.1.62 ? x * 135000-140000, SDS-PAGE, mature protein 656061 3.2.1.62 ? x * 138000, SDS-PAGE -, 750706 3.2.1.62 dimer - 208757 3.2.1.62 dimer 2 * 160000, SDS-PAGE 208756, 208757 3.2.1.62 monomer - 208751 3.2.1.62 monomer 1 * 130000, SDS-PAGE 208752 3.2.1.62 monomer 1 * 135000, SDS-PAGE 208750 3.2.1.62 monomer 1 * 160000, SDS-PAGE, mature brush-border form after proteolytic cleavage of the precursor form 208753, 208754, 208755 3.2.1.62 monomer or dimer x * 34000 + x * 25000, SDS-PAGE 749905 3.2.1.62 additional information LPH encompasses four homologous domains, which presumably have evolved from two subsequent duplications of one ancestral gene, domain organization, overview. The profragment, LPHalpha, comprises homologous domains I and II and functions as an intramolecular chaperone in the context of the brush-border LPHbeta region of LPH. Inter-relationship between homologous domains III and IV of LPHbeta implication in the overall structure, function, and trafficking of LPH, overview. Isolated homologous domain III is transport-competent per se and sorted to the apical membrane in polarized cells. Nevertheless, it neither dimerizes nor acquires complete phlorizin hydrolase activity 709142