1.5.1.25 dimer 2 * 45000, SDS-PAGE 1.5.1.25 homodimer - 1.5.1.25 homodimer 2 * 33776, sequence calculation 1.5.1.25 additional information each subunit contains two distinct domains linked by an alpha-helix. The first domain (a dinucleotide binding domain) binds NADPH or NADP+ and is built around a Rossmann fold-like motif. The second domain is the dimerization domain and is responsible for recognition and binding of thyroid hormones