4.2.3.87 (2E,6E)-farnesyl diphosphate - Vitis vinifera alpha-guaiene + diphosphate - ? 415852 4.2.3.87 (2E,6E)-farnesyl diphosphate - Aquilaria crassna alpha-guaiene + diphosphate 13% yield ? 415852 4.2.3.87 (2E,6E)-farnesyl diphosphate - Pogostemon cablin alpha-guaiene + diphosphate 13% yield with recombinant enzyme ? 415852 4.2.3.87 (2E,6E)-farnesyl diphosphate - Pogostemon cablin alpha-guaiene + diphosphate main product with 29.4% yield ? 415852 4.2.3.87 additional information GC-MS libraries enable identification of the major products as alpha-guaiene (44%) and alpha-bulnesene (35%, also known as delta-guaiene). A number of minor products are also produced, putatively annotated as epiglobulol, gamma-gurjunene, and pogostol, that also exhibit the characteristic guaiene-type 5,7 bicyclic carbon skeleton of the peppery aroma compound rotundone. Substrate analysis of wild-type and mutant enzymes compared to selinene synthase, EC 4.2.3.86 Vitis vinifera ? - ? 89