4.2.3.141 (13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate + H2O i.e. 8alpha-hydroxy-copalyl diphosphate Salvia sclarea (13R)-sclareol + diphosphate - ? 444057 4.2.3.141 (13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate + H2O i.e. 8alpha-hydroxy-copalyl diphosphate, the enzyme shows strong stereoselectivity in formation of the (13R)-epimer, residue N431 is responsible Salvia sclarea (13R)-sclareol + diphosphate - ? 444057 4.2.3.141 (13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate + H2O - Salvia sclarea sclareol + diphosphate - ? 444058 4.2.3.141 (9S,10S)-copalyl diphosphate + H2O - Salvia sclarea manool + diphosphate - ? 422200 4.2.3.141 labda-13-en-8-ol diphosphate + H2O - Salvia sclarea sclareol + diphosphate - ? 423797 4.2.3.141 additional information in coupled enzyme assays with labda-13-en-8-ol diphosphate synthase, sclareol is the major product with minor amounts of manool, manoyl oxides and epi-manoyl oxide as secondary products Salvia sclarea ? - ? 89 4.2.3.141 additional information no substrate: geranylgeranyl diphosphate Salvia sclarea ? - ? 89 4.2.3.141 additional information GC-MS reaction product analysis Salvia sclarea ? - ? 89 4.2.3.141 additional information GC-MS reaction product analysis. Molecular docking of enzyme products in to the active site of the enzyme, modeling, overview Salvia sclarea ? - ? 89