4.2.1.B7 (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate generation of (8Z)-colneleic acid from the (8R)-deuterated (9S)-hydroperoxide is accompanied by retention (98%) of most of the deuterium label Clematis vitalba (8Z)-9-[(1E,3E)-nona-1,3-dien-1-yloxy]non-8-enoic acid + H2O i.e. (8Z)-colneleic acid ? 407611 4.2.1.B7 (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate - Clematis vitalba (8Z)-9-[(1E,3Z)-nona-1,3-dien-1-yloxy]non-8-enoic acid + H2O i.e. (8Z)-colneleic acid ? 407612 4.2.1.B7 (9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate - Clematis vitalba (8Z)-9-[(1E,3Z,6Z)-nona-1,3,6-trien-1-yloxy]non-8-enoic acid i.e. (8Z)-colnelenic acid ? 407616 4.2.1.B7 additional information irrespective of which hydroperoxide regioisomer served as the substrate, divinyl ether synthases abstracting the pro-R hydrogen generate divinyl ethers having an (E)-vinyl ether double bond, whereas enzymes abstracting the pro-S hydrogen produce divinyl ethers having a (Z)-vinyl ether double bond Clematis vitalba ? - ? 89