2.1.1.B84 additional information IpeOMT1 does not catalyze the 7'-O-methylation of 7'-O-demethylcephaeline. IpeOMT1 shows broad substrate specificity towards the intermediates in emetine biosynthesis. IpeOMT1 dominantly catalyzes 6-O-methylation of the 6,7-dihydroxy- and 6-hydroxy-7-methoxyisoquinolines. The regional substrate specificity at the last step of emetine biosynthesis is restricted to 6'-O-methylation Carapichea ipecacuanha ? - ? 89 2.1.1.B84 additional information the enzyme is also active on 7'-O-demethylcephaeline forming cephaeline, overview Carapichea ipecacuanha ? - ? 89 2.1.1.B84 additional information substrate specificity of CiOMT2, overview Carapichea ipecacuanha ? - ? 89 2.1.1.B84 S-adenosyl-L-methionine + (R)-norprotosinomenine - Carapichea ipecacuanha S-adenosyl-L-homocysteine + ? - ? 417581 2.1.1.B84 S-adenosyl-L-methionine + (R,S)-isococlaurine - Carapichea ipecacuanha S-adenosyl-L-homocysteine + ? - ? 417582 2.1.1.B84 S-adenosyl-L-methionine + (R,S)-isoorientaline - Carapichea ipecacuanha S-adenosyl-L-homocysteine + ? - ? 417583 2.1.1.B84 S-adenosyl-L-methionine + (R,S)-norcoclaurine - Carapichea ipecacuanha S-adenosyl-L-homocysteine + ? - ? 417584 2.1.1.B84 S-adenosyl-L-methionine + (R,S)-protosinomenine - Carapichea ipecacuanha S-adenosyl-L-homocysteine + ? - ? 417585 2.1.1.B84 S-adenosyl-L-methionine + (S)-4'-O-methyllaudanosoline - Carapichea ipecacuanha S-adenosyl-L-homocysteine + ? - ? 417586 2.1.1.B84 S-adenosyl-L-methionine + (S)-norprotosinomenine - Carapichea ipecacuanha S-adenosyl-L-homocysteine + ? - ? 417587