2.1.1.72 additional information S-adenosyl-L-methionine plays a crucial role in reorientation of the enzyme in DNA with mutationally altered Ade residues to 2-aminopurine, overview Tequatrovirus T4 ? - ? 89 2.1.1.72 additional information DNA substrate specificities of wild-type and mutant enzymes Tequatrovirus T4 ? - ? 89 2.1.1.72 additional information enzyme and S-adenosyl-L-methionine form a catalytically active complex Tequatrovirus T4 ? - ? 89 2.1.1.72 additional information enzyme binds also nonspecific to DNA, linear diffusion along the DNA, overview Tequatrovirus T4 ? - ? 89 2.1.1.72 additional information substrate specificity with different oligonucleotides, substrate binding specificity, overview Escherichia coli ? - ? 89 2.1.1.72 additional information the common methyl transfer from S-adenosyl-L-methionine to an exocyclic amino group, catalyzed by many enzymes, does not dictate a common kinetic scheme for MTases, comparison to T4Dam MTase from bacteriophage T4 Bacillus amyloliquefaciens ? - ? 89 2.1.1.72 additional information catalyzes the transfer of a methyl group to the C5 position of the 3'-side cytosine of each strand of the recognition sequence, M.EcoRII binding is diminished by factors of 5-30 but the catalytic activity is either abolished or reduced 4-80fold when trans-anti-B[a]P-N2-dG lesions are introduced into the EcoRII recognition sequence, methylation rates are also diminished and in some cases entirely abolished, depending on the position of the lesion within the recognition sequence Escherichia coli ? - ? 89 2.1.1.72 additional information DNA methylation by DAM may not globally affect gene transcription by physically blocking access of transcription factors to binding sites, Dam is down regulated in the stationary phase, which correlates with the enrichment of GATC in binding sites for CRP and Sigma 38 Escherichia coli ? - ? 89 2.1.1.72 additional information the enzyme is part of the type II restriction-modification system AhdI, overview Aeromonas hydrophila ? - ? 89 2.1.1.72 additional information Dam-dependent regulation of secretion of pathogenicity island 1 is transmitted via transcriptional regulator HilD Salmonella enterica ? - ? 89