2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + 3-mercaptopropanoic acid	-	Methanosarcina barkeri	methyl-3-mercaptopropanoic acid + a [Co(I) methanol-specific corrinoid protein]	-	r	418345	
2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M	-	Methanosarcina barkeri	methyl-CoM + a [Co(I) methanol-specific corrinoid protein]	-	?	417877	
2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M	-	Methanosarcina barkeri	methyl-CoM + a [Co(I) methanol-specific corrinoid protein]	-	r	417877	
2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M	the enzyme methylcobamide:CoM methyltransferase, MT2, catalyzes the transfer of the methyl group from the MT1-bound methylcobamide prosthetic group to coenzyme M	Methanosarcina barkeri	methyl-CoM + a [Co(I) methanol-specific corrinoid protein]	-	r	417877	
2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M	-	Methanosarcina barkeri Fusaro, DSM 804	methyl-CoM + a [Co(I) methanol-specific corrinoid protein]	-	r	417877	
2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M	-	Methanosarcina barkeri Fusaro / DSM 804	methyl-CoM + a [Co(I) methanol-specific corrinoid protein]	-	r	417877	
2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + CoM	-	Methanosarcina barkeri	methyl-CoM + a [Co(I) methanol-specific corrinoid protein]	-	?	454233	
2.1.1.246	a [methyl-Co(III) methanol-specific corrinoid protein] + CoM	-	Methanosarcina barkeri	methyl-CoM + a [Co(I) methanol-specific corrinoid protein]	-	r	454233	
2.1.1.246	additional information	 transferase MtaA catalyzes the transfer of the methyl group from methylated transferase MtaBC to coenzyme M. Instead of methylated transferase MtaBC, MtaA can also use free methylcobalamin as the methyl donor. MtaA activates coenzyme M for nucleophilic attack of the methyl group of the methylcobamide	Methanosarcina barkeri	?	-	?	89	
2.1.1.246	additional information	conversions of monomethylamine and dimethylamine to CH3-SCoM are dependent upon MT2-A, and are not supported by MT2-M. In contrast, MT2-M acts specifically in metabolism of methanol, but does not substitute for MT2-A in conversion of monomethylamine or dimethylamine. Nevertheless, both isozymes are capable of supporting the conversion of trimethylamine	Methanosarcina barkeri	?	-	?	89