2.1.1.157	2 S-adenosyl-L-methionine + sarcosine	(overall reaction)	Halorhodospira halochloris	2 S-adenosyl-L-homocysteine + betaine	-	?	424074	
2.1.1.157	additional information	the enzyme catalyzes the last 2 steps of betaine synthesis from glycine in a 3-step process	Halorhodospira halochloris	?	-	?	89	
2.1.1.157	additional information	the enzyme catalyzes the last 2 steps of betaine synthesis from glycine in a 3-step process	Actinopolyspora halophila	?	-	?	89	
2.1.1.157	additional information	the enzyme catalyzes the last 2 steps of betaine synthesis from glycine in a 3-step process, betaine is required for balancing osmotic pressure under high salt living conditions	Halorhodospira halochloris	?	-	?	89	
2.1.1.157	additional information	the enzyme is involved in the alternate biosynthesis of betaine, which is an important osmoprotectant and is synthesized in response to abiotic stress	Aphanothece halophytica	?	-	?	89	
2.1.1.157	additional information	enzyme shows strict substrate specificity	Aphanothece halophytica	?	-	?	89	
2.1.1.157	additional information	the enzyme has overlapping activities with the enzyme catalyzing the prior reaction steps	Halorhodospira halochloris	?	-	?	89	
2.1.1.157	additional information	the enzyme has overlapping activities with the enzyme catalyzing the prior reaction steps	Actinopolyspora halophila	?	-	?	89	
2.1.1.157	additional information	the enzyme shows strict specificity for glycine and sarcosine as substrates, no activity with ethanolamine, monomethylethanolamine, nor several L-amino acid, overview	Halorhodospira halochloris	?	-	?	89	
2.1.1.157	additional information	the broad substrate methyltransferase, glycine sarcosine dimethylglycine methyltransferase, GSDMT, purified from the halophilic methanoarchaeon Methanohalophilus portucalensis strain FDF1, has been shown to possess glycine N-methyltransferase (GMT), sarcosine N-methyltransferase (SMT) and dimethylglycine N-methyltransferase (DMT) activities. SDMT possesses sarcosine N-methyltransferase (SMT) and dimethylglycine N-methyltransferase (DMT) activities	Methanohalophilus portucalensis	?	-	?	89