1.14.14.148 (+)-columbianetin + [reduced NADPH-hemoprotein reductase] + O2 - Peucedanum praeruptorum angelicin + acetone + [oxidized NADPH-hemoprotein reductase] + H2O - ? 402272 1.14.14.148 (+)-columbianetin + [reduced NADPH-hemoprotein reductase] + O2 the enzyme is involved in angular furanocoumarin pathway Pastinaca sativa angelicin + acetone + [oxidized NADPH-hemoprotein reductase] + H2O negligible amounts of a hydroxylated columbianetin by-product ? 402272 1.14.14.148 (+)-columbianetin + [reduced NADPH-hemoprotein reductase] + O2 angelicin synthase attacks columbianetin by syn-elimination of hydrogen from C-3' Pastinaca sativa angelicin + acetone + [oxidized NADPH-hemoprotein reductase] + H2O negligible amounts of a hydroxylated columbianetin by-product ? 402272 1.14.14.148 syn-[3'D]columbianetin + [reduced NADPH-hemoprotein reductase] + O2 - Pastinaca sativa syn-[3'D](anti-3'-hydroxy)-columbianetin + [oxidized NADPH-hemoprotein reductase] + H2O - ? 406724