1.14.13.200	tetracenomycin A2 + 2 O2 + 2 NAD(P)H + 2 H+	-	Streptomyces glaucescens	tetracenomycin C + 2 NAD(P)+ + H2O	enzyme is responsible for the hydroxylation of tetracenomycin A2 at positions C-4, C-4a, and C-12a to give tetracenomycin C	?	427550	
1.14.13.200	tetracenomycin A2 + 2 O2 + 2 NAD(P)H + 2 H+	-	Streptomyces olivaceus	tetracenomycin C + 2 NAD(P)+ + H2O	quantitative conversion	?	427550	
1.14.13.200	tetracenomycin A2 + 2 O2 + 2 NAD(P)H + 2 H+	biosynthesis tetracenomycin C, a polyketide antitumor antibiotic	Streptomyces glaucescens	tetracenomycin C + 2 NAD(P)+ + H2O	-	?	427550	
1.14.13.200	tetracenomycin A2 + 2 O2 + 2 NAD(P)H + 2 H+	-	Streptomyces olivaceus Tue2353	tetracenomycin C + 2 NAD(P)+ + H2O	quantitative conversion	?	427550	
1.14.13.200	tetracenomycin A2 + 2 O2 + 2 NADH + 2 H+	tetracenomycin A2 i.e. methyl 10,12-dihydroxy-3,8-dimethoxy-1-methyl-6,11-dioxo-6,11-dihydrotetracene-2-carboxylate. The enzyme prefers NADPH over NADH as an electron donor	Streptomyces glaucescens	tetracenomycin C + 2 NAD+ + H2O	tetracenomycin C = methyl (6aR,7S,10aR)-6a,7,10a,12-tetrahydroxy-3,8-dimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate	?	428967	
1.14.13.200	tetracenomycin A2 + 2 O2 + 2 NADPH + 2 H+	tetracenomycin A2 i.e. methyl 10,12-dihydroxy-3,8-dimethoxy-1-methyl-6,11-dioxo-6,11-dihydrotetracene-2-carboxylate. The enzyme prefers NADPH over NADH as an electron donor	Streptomyces glaucescens	tetracenomycin C + 2 NADP+ + H2O	tetracenomycin C = methyl (6aR,7S,10aR)-6a,7,10a,12-tetrahydroxy-3,8-dimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate	?	428968	
1.14.13.200	tetracenomycin B2 + 2 O2 + 2 NAD(P)H + 2 H+	natural reaction in Streptomyces olivaceus	Streptomyces olivaceus	8-demethyl tetracenomycin C + 2 NAD(P)+ + H2O	-	?	429406	
1.14.13.200	tetracenomycin B2 + 2 O2 + 2 NAD(P)H + 2 H+	natural reaction in Streptomyces olivaceus	Streptomyces olivaceus Tue2353	8-demethyl tetracenomycin C + 2 NAD(P)+ + H2O	-	?	429406