3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O - Escherichia coli 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O committed step of folate synthesis in bacteria Escherichia coli 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O the second step in the pterin branch of the folate synthesis pathway Lactococcus lactis 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O no activity against deoxynucleoside triphosphates Lactococcus lactis 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O the enzyme is far more active against dGTP, 8-oxo-GTP, dTTP, and other nucleoside and deoxynucleoside 3'-triphosphates than against 7,8-dihydroneopterin 3'-triphosphate Arabidopsis thaliana 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O key enzyme in the folate pathway Escherichia coli 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O the enzyme participates in a folate biosynthesis pathway Escherichia coli 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O catalytic efficiency of the enzyme is far higher for dGTP Arabidopsis thaliana 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O no detectable activity with GTP, ATP, TTP, CTP, the corresponding deoxynucleoside triphosphates, 8-oxo-dGTP, NADH, NAD, diadenosine tri- or tetraphosphate, ADP-ribose, UDP-glucose, or coenzyme A (the detection limit is less than 1% of the activity with 7,8-dihydroneopterin 3'-triphosphate) Lactococcus lactis 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329 3.6.1.67 7,8-dihydroneopterin 3'-triphosphate + H2O the second step in the pterin branch of the folate synthesis pathway Lactococcus lactis NZ9000 7,8-dihydroneopterin 3'-phosphate + diphosphate - ? 427329