1.8.98.2 2-Cys peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + GSH - Pisum sativum 2-Cys peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + GSSG - ? 440662 1.8.98.2 additional information no activity with CTP, UTP, dCTP, or dTTP Homo sapiens ? - ? 89 1.8.98.2 additional information catalyzes the reduction of cysteine sulfinic acid to sulfenic acid in oxidized proteins and protects them from inactivation Mus musculus ? - ? 89 1.8.98.2 additional information catalyzes the reduction of cysteine sulfinic acid to sulfenic acid in oxidized proteins and protects them from inactivation Homo sapiens ? - ? 89 1.8.98.2 additional information catalyzes the deglutathionylation of actin Homo sapiens ? - ? 89 1.8.98.2 additional information promotes the reversal of cysteine modified PTP1B to its reduced and enzymatically active form Homo sapiens ? - ? 89 1.8.98.2 additional information reduction of cysteine sulfinic acid to sulfenic acid in proteins subject to oxidative stress Homo sapiens ? - ? 89 1.8.98.2 additional information assay conditions optimization, overview Arabidopsis thaliana ? - ? 89 1.8.98.2 additional information enzyme is able to act as a redox-dependent sulfinic acid reductase and as a redox-independent nuclease enzyme. Sulfiredoxin functions as a nuclease enzyme that can use single-stranded and double-stranded DNAs as substrates. The active site of the reductase function of sulfiredoxin is not involved in its nuclease function Arabidopsis thaliana ? - ? 89 1.8.98.2 additional information AtSrx has sulfinic acid reductase activity to catalyze the reduction of the overoxidized form of 2-Cys Prx in vitro and in vivo Arabidopsis thaliana ? - - 89