1.7.1.13	2-amino-5-cyanopyrrolo[2,3-d]pyrimidin-4-one + 2 NADPH + 2 H+	natural substrate	Escherichia coli	2-amino-5-amino-methyl-pyrrolo[2,3-d]pyrimidin-4-one + 2 NADP+	-	?	424479	
1.7.1.13	2-amino-5-cyanopyrrolo[2,3-d]pyrimidine + 2 NADPH + 2 H+	analogue of natural substrate, poor substrate	Escherichia coli	2-amino-5-amino-methyl-pyrrolo[2,3-d]pyrimidine + 2 NADP+	-	?	425399	
1.7.1.13	5-cyanopyrrolo[2,3-d]pyrimidin-4-one + 2 NADPH + 2 H+	analogue of natural substrate	Escherichia coli	5-amino-methyl-pyrrolo[2,3-d]pyrimidin-4-one + 2 NADP+	-	?	425798	
1.7.1.13	7-cyano-7-carba-2-deaminoguanine + 2 NADPH + 2 H+	-	Escherichia coli	7-aminomethyl-7-carba-2-deaminoguanine + 2 NADP+	-	?	440974	
1.7.1.13	7-cyano-7-carbaguanine + 2 NADPH + 2 H+	-	Escherichia coli	7-aminomethyl-7-carbaguanine + 2 NADP+	-	?	440975	
1.7.1.13	7-cyano-7-carbaguanine + 2 NADPH + 2 H+	-	Vibrio cholerae O1	7-aminomethyl-7-carbaguanine + 2 NADP+	-	?	440975	
1.7.1.13	7-cyano-7-carbaguanine + 2 NADPH + 2 H+	-	Pectobacterium carotovorum subsp. carotovorum	7-aminomethyl-7-carbaguanine + 2 NADP+	-	?	440975	
1.7.1.13	7-cyano-7-carbaguanine + 2 NADPH + 2 H+	-	Vibrio cholerae O1 ATCC 39315	7-aminomethyl-7-carbaguanine + 2 NADP+	-	?	440975	
1.7.1.13	7-cyano-7-carbaguanine + 2 NADPH + 2 H+	-	Pectobacterium carotovorum subsp. carotovorum PCC21	7-aminomethyl-7-carbaguanine + 2 NADP+	-	?	440975	
1.7.1.13	7-cyano-7-deazaguanine + 2 NADPH + 2 H+	-	Escherichia coli	queuine + 2 NADP+	-	?	378400