1.14.13.83	precorrin-3A + NADH + H+ + O2	the Brucella melitensis enzyme is fully active in vitro (20 mM Tris-HCl buffer, pH 8.0, with 100 mM NaCl, S-adenosyl-L-methionine (SAM), 5-aminolevulinic acid (ALA) and NADPH, aerobic, dark, 4°C) and the mononuclear non-heme iron is reducible by dithionite and then is able to react with NO as oxygen analogue in the presence of the substrate	Brucella melitensis	precorrin-3B + NAD+ + H2O	-	?	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	the Brucella melitensis enzyme is fully active in vitro (20 mM Tris-HCl buffer, pH 8.0, with 100 mM NaCl, S-adenosyl-L-methionine (SAM), 5-aminolevulinic acid (ALA) and NADPH, aerobic, dark, 4°C) and the mononuclear non-heme iron is reducible by dithionite and then is able to react with NO as oxygen analogue in the presence of the substrate	Brucella melitensis 16M	precorrin-3B + NAD+ + H2O	-	?	363718	
1.14.13.83	additional information	biosynthesis of vitamin B12	Pseudomonas denitrificans (nom. rej.)	?	-	?	89	
1.14.13.83	additional information	the enzyme is involved in the mechanism of the ring contraction process during vitamin B12 biosynthesis, comparison to the ring contraction process reaction pathway under anaerobic conditions in Propionibacterium freudenreichii ssp. shermanii, overview	Pseudomonas denitrificans (nom. rej.)	?	-	?	89	
1.14.13.83	precorrin-3 + NADH + H+ + O2	-	Pseudomonas denitrificans (nom. rej.)	precorrin-3x + NAD+ + H2O	-	ir	363719	
1.14.13.83	precorrin-3 + NADH + H+ + O2	biosynthesis of vitamin B12, part of the ring contractase system for oxidative ring contraction	Pseudomonas denitrificans (nom. rej.)	precorrin-3x + NAD+ + H2O	-	ir	363719	
1.14.13.83	precorrin-3A + NADH + H+ + O2	-	Pseudomonas denitrificans (nom. rej.)	precorrin-3B + NAD+ + H2O	-	?	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	-	Pseudomonas denitrificans (nom. rej.)	precorrin-3B + NAD+ + H2O	-	ir	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	-	Pseudomonas denitrificans (nom. rej.)	precorrin-3B + NAD+ + H2O	aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4	ir	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	biosynthesis of vitamin B12	Pseudomonas denitrificans (nom. rej.)	precorrin-3B + NAD+ + H2O	aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4	ir	363718