4.3.1.15 2,3-diaminopropanoate + H2O precursor of a neurotoxin in Lathyrus sativus seed extracts Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + NH3 - ? 390585 4.3.1.15 2,3-diaminopropanoate + H2O precursor of a neurotoxin in Lathyrus sativus seed extracts Salmonella enterica subsp. enterica serovar Typhimurium PU011 pyruvate + NH3 - ? 390585 4.3.1.15 2,3-diaminopropanoate + H2O specific role for the enzyme in degrading 2,3-diaminopropanoate to avoid metabolic stress Salmonella enterica pyruvate + 2 NH3 - ? 444137 4.3.1.15 2,3-diaminopropanoate + H2O diaminopropionate ammonia-lyase-dependent degradation of 2,3-diaminopropanoate to pyruvate proceeds through an unbound 2-aminoacrylate intermediate Salmonella enterica pyruvate + 2 NH3 - ? 444137 4.3.1.15 2,3-diaminopropanoate + H2O specific role for the enzyme in degrading 2,3-diaminopropanoate to avoid metabolic stress Salmonella enterica DM14828 pyruvate + 2 NH3 - ? 444137 4.3.1.15 2,3-diaminopropanoate + H2O diaminopropionate ammonia-lyase-dependent degradation of 2,3-diaminopropanoate to pyruvate proceeds through an unbound 2-aminoacrylate intermediate Salmonella enterica DM14828 pyruvate + 2 NH3 - ? 444137 4.3.1.15 2-[5-amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-(1-benzyl-2-oxo-2-thiazol-2-yl-ethyl)-acetamide + H2O - Salmonella enterica subsp. enterica serovar Typhimurium ? - ? 453534 4.3.1.15 D-2,3-diaminopropanoate + 2 H2O - Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + 2 NH3 - ? 430079 4.3.1.15 D-2,3-Diaminopropanoate + H2O - Salmonella enterica subsp. enterica serovar Typhimurium Pyruvate + NH3 - ? 2237 4.3.1.15 D-2,3-Diaminopropanoate + H2O - Pseudomonas fluorescens Pyruvate + NH3 - ? 2237 4.3.1.15 D-2,3-Diaminopropanoate + H2O - Devosia riboflavina Pyruvate + NH3 - ? 2237 4.3.1.15 D-2,3-Diaminopropanoate + H2O - Pseudomonas sp. Pyruvate + NH3 - ? 2237 4.3.1.15 D-2,3-Diaminopropanoate + H2O - Streptomyces ruber Pyruvate + NH3 - ? 2237 4.3.1.15 D-2,3-Diaminopropanoate + H2O - Escherichia coli Pyruvate + NH3 - ? 2237 4.3.1.15 D-2,3-Diaminopropanoate + H2O only 12% of the activity with L-2,3-diaminopropanoate Pseudomonas sp. Pyruvate + NH3 - ? 2237 4.3.1.15 D-2,3-diaminopropanoate + H2O - Escherichia coli pyruvate + 2 NH3 - ? 445374 4.3.1.15 D-2,3-diaminopropanoate + H2O the enzyme degrades both the D and L forms of diaminopropionic acid. A phosphate group is located in the active site of the enzyme and expulsion of this phosphate is probably essential to bring Asp125 to a conformation suitable for proton abstraction from the substrate Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + 2 NH3 - ? 445374 4.3.1.15 D-2,3-diaminopropanoate + H2O the enzyme degrades both the D and L forms of diaminopropionic acid. A phosphate group is located in the active site of the enzyme and expulsion of this phosphate is probably essential to bring Asp125 to a conformation suitable for proton abstraction from the substrate Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720 pyruvate + 2 NH3 - ? 445374 4.3.1.15 D-serine - Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + NH3 - ? 2238 4.3.1.15 D-serine + H2O - Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + NH3 - ? 368442 4.3.1.15 D-serine + H2O - Escherichia coli pyruvate + NH3 - ? 368442 4.3.1.15 DL-2,3-diaminopropanoate + 2 H2O - Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + 2 NH3 - ? 430132 4.3.1.15 DL-2,3-diaminopropanoate + H2O - Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + NH3 - ? 368441 4.3.1.15 DL-2,3-diaminopropanoate + H2O - Escherichia coli pyruvate + NH3 - ? 368441 4.3.1.15 L-2,3-diaminopropanoate + 2 H2O - Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + 2 NH3 - ? 430282 4.3.1.15 L-2,3-Diaminopropanoate + H2O - Salmonella enterica subsp. enterica serovar Typhimurium Pyruvate + NH3 - ? 2236 4.3.1.15 L-2,3-Diaminopropanoate + H2O - Pseudomonas fluorescens Pyruvate + NH3 - ? 2236 4.3.1.15 L-2,3-Diaminopropanoate + H2O - Devosia riboflavina Pyruvate + NH3 - ? 2236 4.3.1.15 L-2,3-Diaminopropanoate + H2O - Pseudomonas sp. Pyruvate + NH3 - ? 2236 4.3.1.15 L-2,3-Diaminopropanoate + H2O - Streptomyces ruber Pyruvate + NH3 - ? 2236 4.3.1.15 L-2,3-Diaminopropanoate + H2O - Escherichia coli Pyruvate + NH3 - ? 2236 4.3.1.15 L-2,3-diaminopropanoate + H2O - Escherichia coli pyruvate + 2 NH3 - ? 445584 4.3.1.15 L-2,3-diaminopropanoate + H2O the enzyme degrades both the D and L forms of diaminopropionic acid. A phosphate group is located in the active site of the enzyme and expulsion of this phosphate is probably essential to bring Asp125 to a conformation suitable for proton abstraction from the substrate Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + 2 NH3 - ? 445584 4.3.1.15 L-2,3-diaminopropanoate + H2O the enzyme degrades both the D and L forms of diaminopropionic acid. A phosphate group is located in the active site of the enzyme and expulsion of this phosphate is probably essential to bring Asp125 to a conformation suitable for proton abstraction from the substrate Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720 pyruvate + 2 NH3 - ? 445584 4.3.1.15 L-cysteine - Salmonella enterica subsp. enterica serovar Typhimurium ? - ? 2224 4.3.1.15 L-serine - Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + NH3 - ? 1922 4.3.1.15 L-serine - Escherichia coli pyruvate + NH3 - ? 1922 4.3.1.15 additional information the enzyme is induced only by L-2,3-diaminopropionate or D-2,3-diaminopropanoate Salmonella enterica subsp. enterica serovar Typhimurium ? - ? 89