4.1.3.16	2-Keto-4-hydroxybutyrate	D-isomer favoured	Bos taurus	Pyruvate + formaldehyde	-	?	1843	
4.1.3.16	2-Keto-4-hydroxybutyrate	metabolism of L-homoserine	Bos taurus	?	-	?	369435	
4.1.3.16	3-(4-hydroxyphenyl)pyruvate + glyoxylate	-	Rattus norvegicus	?	-	?	453464	
4.1.3.16	3-(4-imidazole)pyruvate + glyoxylate	-	Rattus norvegicus	?	-	?	453465	
4.1.3.16	4-Hydroxy-2-oxoglutarate	-	Homo sapiens	Pyruvate + glyoxylate	-	?	1842	
4.1.3.16	4-Hydroxy-2-oxoglutarate	-	Rattus norvegicus	Pyruvate + glyoxylate	-	?	1842	
4.1.3.16	4-Hydroxy-2-oxoglutarate	-	Bos taurus	Pyruvate + glyoxylate	-	?	1842	
4.1.3.16	4-Hydroxy-2-oxoglutarate	-	Homo sapiens	Pyruvate + glyoxylate	-	r	1842	
4.1.3.16	4-Hydroxy-2-oxoglutarate	-	Escherichia coli	Pyruvate + glyoxylate	-	r	1842	
4.1.3.16	4-Hydroxy-2-oxoglutarate	both stereoisomers	Rattus norvegicus	Pyruvate + glyoxylate	-	?	1842	
4.1.3.16	4-Hydroxy-2-oxoglutarate	both stereoisomers	Bos taurus	Pyruvate + glyoxylate	-	?	1842	
4.1.3.16	4-hydroxy-2-oxoglutarate	-	Rattus norvegicus	?	-	?	369436	
4.1.3.16	4-hydroxy-2-oxoglutarate	catabolism of hydroxyproline, condensation physiologically less important	Mammalia	?	-	?	369436	
4.1.3.16	acetaldehyde + glyoxylate	-	Rattus norvegicus	?	-	?	453466	
4.1.3.16	D-4-hydroxy-2-oxoglutarate	-	Rattus norvegicus	pyruvate + glyoxylate	-	?	423238	
4.1.3.16	D-4-hydroxy-2-oxoglutarate	-	Bos taurus	pyruvate + glyoxylate	-	r	423238	
4.1.3.16	Glyoxylate + pyruvate	specific, codensation favoured, Keq: 0.73 mM	Rattus norvegicus	4-Hydroxy-2-ketoglutarate	-	?	1845	
4.1.3.16	Glyoxylate + pyruvate	3-substituted analogs	Rattus norvegicus	4-Hydroxy-2-ketoglutarate	-	?	1845	
4.1.3.16	Glyoxylate + pyruvate	higher specificity for pyruvate than for glyoxylate	Bos taurus	4-Hydroxy-2-ketoglutarate	-	?	1845	
4.1.3.16	L-4-hydroxy-2-oxoglutarate	-	Rattus norvegicus	pyruvate + glyoxylate	-	?	423711	
4.1.3.16	L-4-hydroxy-2-oxoglutarate	-	Bos taurus	pyruvate + glyoxylate	-	?	423711	
4.1.3.16	L-4-hydroxy-2-oxoglutarate	-	Bos taurus	pyruvate + glyoxylate	-	r	423711	
4.1.3.16	additional information	-	Rattus norvegicus	?	-	?	89	
4.1.3.16	additional information	mechanism	Bos taurus	?	-	?	89	
4.1.3.16	additional information	specific for glyoxylate and pyruvate	Rattus norvegicus	?	-	?	89	
4.1.3.16	additional information	functional role of SH-groups, conformational changes during catalysis	Bos taurus	?	-	?	89	
4.1.3.16	additional information	Keq: 11 mM	Bos taurus	?	-	?	89	
4.1.3.16	additional information	equilibrium favours condensation, Keq: 0.73 1/mM	Rattus norvegicus	?	-	?	89	
4.1.3.16	additional information	2-keto-4-hydroxy-4-methylglutarate, 2-keto-3-deoxy-6-phosphoclucanate cleaved at slow rate	Bos taurus	?	-	?	89	
4.1.3.16	additional information	acts on both stereoisomers	Rattus norvegicus	?	-	?	89	
4.1.3.16	additional information	acts on both stereoisomers	Bos taurus	?	-	?	89	
4.1.3.16	additional information	2-keto-3-deoxyglucarate and 2-keto-4,5-dihydroxyvalerate cleaved at slow rate	Rattus norvegicus	?	-	?	89	
4.1.3.16	additional information	2-keto-3-deoxyglucarate and 2-keto-4,5-dihydroxyvalerate cleaved at slow rate	Bos taurus	?	-	?	89	
4.1.3.16	additional information	enzyme performs a retro-aldol cleavage reaction reminiscent of the trimeric 2-keto-3-deoxy-6-phosphogluconate aldolases	Homo sapiens	?	-	?	89	
4.1.3.16	additional information	enzyme shows no stereospecificity in catalyzing the aldol cleavage of the two optical isomers of 2-keto-4-hydroxyglutarate. Enzyme also catalyzes the beta-decarboxylation of oxalacetate, its decarboxylase/aldolae activity ratio is lower than that seen with the pure enzyme from either bovine liver or Escherichia coli	Bos taurus	?	-	?	89	
4.1.3.16	Oxaloacetate	-	Rattus norvegicus	CO2 + pyruvate	-	?	1844	
4.1.3.16	Oxaloacetate	-	Bos taurus	CO2 + pyruvate	-	?	1844	
4.1.3.16	Oxaloacetate	beta-decarboxylation, about 50% as effective as aldolase	Bos taurus	CO2 + pyruvate	-	?	1844	
4.1.3.16	pyruvaldehyde + glyoxylate	-	Rattus norvegicus	?	-	?	453467	
4.1.3.16	Pyruvate + formaldehyde	Keq: 4.1 mM	Bos taurus	2-Keto-4-hydroxybutyrate	-	?	1846	
4.1.3.16	pyruvate + glyoxylate	-	Bos taurus	D-4-hydroxy-2-oxoglutarate	-	r	423985	
4.1.3.16	pyruvic acid ethyl ester + glyoxylate	-	Rattus norvegicus	?	-	?	453468	
4.1.3.16	pyruvic acid methyl ester + glyoxylate	-	Rattus norvegicus	?	-	?	453469