4.1.2.52	(S)-4-hydroxy-2-oxopentanoate	-	Escherichia coli	?	-	?	425200	
4.1.2.52	2-oxo-3-methyl-4-hydroxypentanoate	efficient substrate	Escherichia coli	2-oxobutyrate + acetaldehyde	-	?	425464	
4.1.2.52	2-oxobutanoate + acetaldehyde	-	Escherichia coli	?	-	?	422437	
4.1.2.52	3-deoxy-D-manno-oct-2-ulosonic acid	3-deoxy-D-manno-oct-2-ulosonic acid i.e. KDO	Escherichia coli	?	-	?	422518	
4.1.2.52	4-hydroxy-2-oxo-heptanedioate	-	Escherichia coli	pyruvate + succinic semialdehyde	-	?	421812	
4.1.2.52	4-hydroxy-2-oxoheptane-1,7-dioate	-	Escherichia coli	pyruvate + succinate semialdehyde	-	?	424578	
4.1.2.52	4-hydroxy-2-oxoheptanedioate	-	Escherichia coli	pyruvate + succinate semialdehyde	-	?	421813	
4.1.2.52	4-hydroxy-2-oxohexanoate	-	Escherichia coli	?	-	?	422588	
4.1.2.52	4-hydroxy-2-oxopentanoate	-	Escherichia coli	?	-	?	416308	
4.1.2.52	4-hydroxy-2-oxopentanoic acid	-	Escherichia coli	pyruvate + ?	-	?	422594	
4.1.2.52	additional information	the enzyme exhibits significant oxaloacetate decarboxylase activity, with a kcat value 2.4fold higher than the corresponding value for the aldol cleavage of 4-hydroxy-2-oxopentanoate	Escherichia coli	?	-	?	89	
4.1.2.52	pyruvate + acetaldehyde	-	Escherichia coli	4-hydroxy-2-oxopentanoate	enzyme lacks stereospecific control producing racemic mixtures of 4-hydroxy-2-oxopentanoate i.e. HOPA	?	412795	
4.1.2.52	pyruvate + butyraldehyde	-	Escherichia coli	?	-	?	410147	
4.1.2.52	pyruvate + DL-glyceraldehyde	-	Escherichia coli	?	-	?	393397	
4.1.2.52	pyruvate + glycolaldehyde	-	Escherichia coli	?	-	?	410150	
4.1.2.52	pyruvate + isobutyraldehyde	-	Escherichia coli	?	-	?	410151	
4.1.2.52	pyruvate + pentaldehyde	-	Escherichia coli	?	-	?	410153	
4.1.2.52	pyruvate + propionaldehyde	-	Escherichia coli	?	-	?	410154	
4.1.2.52	pyruvate + succinic semialdehyde	-	Escherichia coli	4-hydroxy-2-oxo-1,7-heptanedioate	enzyme lacks stereospecific control producing racemic mixtures of its physiological substrate, 4-hydroxy-2-oxo-1,7-heptanedioate	?	422030