3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	-	Escherichia coli	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	committed step of folate synthesis in bacteria	Escherichia coli	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	the second step in the pterin branch of the folate synthesis pathway	Lactococcus lactis	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	no activity against deoxynucleoside triphosphates	Lactococcus lactis	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	the enzyme is far more active against dGTP, 8-oxo-GTP, dTTP, and other nucleoside and deoxynucleoside 3'-triphosphates than against 7,8-dihydroneopterin 3'-triphosphate	Arabidopsis thaliana	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	key enzyme in the folate pathway	Escherichia coli	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	the enzyme participates in a folate biosynthesis pathway	Escherichia coli	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	catalytic efficiency of the enzyme is far higher for dGTP	Arabidopsis thaliana	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	no detectable activity with GTP, ATP, TTP, CTP, the corresponding deoxynucleoside triphosphates, 8-oxo-dGTP, NADH, NAD, diadenosine tri- or tetraphosphate, ADP-ribose, UDP-glucose, or coenzyme A (the detection limit is less than 1% of the activity with 7,8-dihydroneopterin 3'-triphosphate)	Lactococcus lactis	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	the second step in the pterin branch of the folate synthesis pathway	Lactococcus lactis NZ9000	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	no activity against deoxynucleoside triphosphates	Lactococcus lactis NZ9000	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	7,8-dihydroneopterin 3'-triphosphate + H2O	no detectable activity with GTP, ATP, TTP, CTP, the corresponding deoxynucleoside triphosphates, 8-oxo-dGTP, NADH, NAD, diadenosine tri- or tetraphosphate, ADP-ribose, UDP-glucose, or coenzyme A (the detection limit is less than 1% of the activity with 7,8-dihydroneopterin 3'-triphosphate)	Lactococcus lactis NZ9000	7,8-dihydroneopterin 3'-phosphate + diphosphate	-	?	427329	
3.6.1.67	dATP + H2O	-	Escherichia coli	dAMP + diphosphate	-	?	141404	
3.6.1.67	additional information	no activity with ATP, GTP, dihydroneopterin phosphate, 4-nitrophenyl hosphate or diphosphate	Escherichia coli	?	-	?	89	
3.6.1.67	additional information	the enzyme also catalyzes the hydrolysis of dATP, 8-hydroxy-dATP, dADP, and 8-hydroxy-dADP	Escherichia coli	?	-	?	89