3.2.2.30 5'-butylthioadenosine + H2O - Arabidopsis thaliana ? - ? 428088 3.2.2.30 5'-chloroadenosine + H2O - Arabidopsis thaliana ? - ? 428089 3.2.2.30 5'-deoxyadenosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 adenine + 5-deoxyribose - ? 446851 3.2.2.30 5'-deoxyadenosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 ATCC 700819 adenine + 5-deoxyribose - ? 446851 3.2.2.30 5'-iodoadenosine + H2O - Arabidopsis thaliana ? - ? 428093 3.2.2.30 5'-isobutylthioadenosine + H2O - Arabidopsis thaliana ? - ? 428094 3.2.2.30 5'-methylthioadenosine + H2O - Arabidopsis thaliana ? - ? 369811 3.2.2.30 5'-methylthioadenosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 adenine + S-methyl-5'-thioribose - ? 446859 3.2.2.30 5'-methylthioadenosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 ATCC 700819 adenine + S-methyl-5'-thioribose - ? 446859 3.2.2.30 5'-phenylthioadenosine + H2O - Arabidopsis thaliana ? - ? 428096 3.2.2.30 5,5'-dithiobis-2-nitrobenzoic acid + H2O - Staphylococcus aureus ? - ? 428098 3.2.2.30 6-amino-6-deoxyfutalosine + H2O - Staphylococcus aureus dehypoxanthine futalosine + adenine - ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O - Escherichia coli dehypoxanthine futalosine + adenine - ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O - Neisseria meningitidis dehypoxanthine futalosine + adenine - ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O - Helicobacter pylori dehypoxanthine futalosine + adenine - ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O the enzyme is part of a modified futalosine pathway for menaquinone biosynthesis Campylobacter jejuni dehypoxanthine futalosine + adenine - ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O 6-amino-6-deoxyfutalosine i.e. 3-[3-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]propanoyl]benzoate. The activity with futalosine ist 2% compared to the activity with 6-amino-6-deoxyfutalosine. The enzyme also has the activity of EC 3.2.2.9, adenosylhomocysteine nucleosidase Campylobacter jejuni dehypoxanthine futalosine + adenine dehypoxanthine futalosine i.e. 3-[3-[(2R,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]propanoyl]benzoate ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O the enzyme is part of a modified futalosine pathway for menaquinone biosynthesis Campylobacter jejuni NCTC 11168 dehypoxanthine futalosine + adenine - ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O 6-amino-6-deoxyfutalosine i.e. 3-[3-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]propanoyl]benzoate. The activity with futalosine ist 2% compared to the activity with 6-amino-6-deoxyfutalosine. The enzyme also has the activity of EC 3.2.2.9, adenosylhomocysteine nucleosidase Campylobacter jejuni NCTC 11168 dehypoxanthine futalosine + adenine dehypoxanthine futalosine i.e. 3-[3-[(2R,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]propanoyl]benzoate ? 416450 3.2.2.30 6-amino-6-deoxyfutalosine + H2O - Helicobacter pylori adenine + dehypoxanthinyl futalosine - ? 431434 3.2.2.30 6-amino-6-deoxyfutalosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 adenine + dehypoxanthinyl futalosine - ? 431434 3.2.2.30 6-amino-6-deoxyfutalosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 ATCC 700819 adenine + dehypoxanthinyl futalosine - ? 431434 3.2.2.30 adenosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 adenine + D-ribose - ? 94810 3.2.2.30 adenosine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 ATCC 700819 adenine + D-ribose - ? 94810 3.2.2.30 adenosine + H2O - Arabidopsis thaliana ? - ? 428131 3.2.2.30 deaminated S-adenosyl-L-homocysteine + H2O 33% activity compared to 5'-methylthioadenosine Escherichia coli ? - ? 428554 3.2.2.30 decarboxylated S-adenosyl-L-homocysteine + H2O 18% activity compared to 5'-methylthioadenosine Escherichia coli ? - ? 428559 3.2.2.30 additional information 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase is a multifunctional enzyme that catalyzes the hydrolysis of the N-ribosidic bond of at least four different adenosine-based metabolites: S-adenosyl-L-homocysteine, 5'-methylthioadenosine, 5'-deoxyadenosine, and 6-amino-6-deoxyfutalosine Helicobacter pylori ? - ? 89 3.2.2.30 additional information no activity toward 5'-methylthioinosine, 5'-isobutylthioinosine, 5'-isobutylthio-3-deaza-adenosine, 5'-methylthio-3-deaza-adenosine, 5'-chloroformycin, 5'-methylthioformycin, 5'-ethylthiotubercidin, S-tubercidinylhomocysteine, S-inosyl-L-homocysteine, S-guanosyl-L-homocysteine, S-cytidylhomocysteine, S-8-aza adenosyl-L-homocysteine, S-n-methyl-3-deaza-adenosyl-L-homocysteine, S-n6-dimethyl-3-deaza-adenosyl-L-homocysteine, sinefungin, S-adenosyl-L-homocysteine dialdehyde, and acyclic adenosyl-L-homocysteine Escherichia coli ? - ? 89 3.2.2.30 S-2-aza-adenosyl-L-homocysteine + H2O 27% activity compared to 5'-methylthioadenosine Escherichia coli ? - ? 428921 3.2.2.30 S-5'-adenosyl-L-homocysteine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 adenine + S-ribosyl-L-homocysteine - ? 448102 3.2.2.30 S-5'-adenosyl-L-homocysteine + H2O - Campylobacter jejuni subsp. jejuni serotype O:2 ATCC 700819 adenine + S-ribosyl-L-homocysteine - ? 448102 3.2.2.30 S-adenosyl-D-homocysteine + H2O 26% activity compared to 5'-methylthioadenosine Escherichia coli ? - ? 428926