2.7.8.1 CDP-choline + 1,2-diacyl-sn-glycerol - Homo sapiens CMP + a phosphatidylcholine - r 436421 2.7.8.1 CDP-choline + 1,2-diacyl-sn-glycerol - Glycine max CMP + a phosphatidylcholine - ? 436421 2.7.8.1 CDP-choline + 1,2-diacylglycerol - Bos taurus CMP + phosphatidylcholine - ? 359127 2.7.8.1 CDP-choline + 1,2-diacylglycerol - Glycine max CMP + phosphatidylcholine - r 359127 2.7.8.1 CDP-choline + 1,2-diacylglycerol - Arabidopsis thaliana CMP + phosphatidylcholine - r 359127 2.7.8.1 CDP-choline + 1,2-diacylglycerol - Chlamydomonas reinhardtii CMP + phosphatidylcholine - ? 359127 2.7.8.1 CDP-choline + 1,2-diacylglycerol preferred substrates in decreasing order: di-10:0 diacylglycerol, di-16:1 diacylglycerol, di-8:0 diacylglycerol, di-18:1 diacylglycerol, 16:0/22:6 diacylglycerol Homo sapiens CMP + phosphatidylcholine - ? 359127 2.7.8.1 CDP-choline + 1,2-diacylglycerol preferred substrates: di-18:1 diacylglycerol, di-16:1 diacylglycerol, 16:0/18:1 diacylglycerol Homo sapiens CMP + phosphatidylcholine - ? 359127 2.7.8.1 CDP-choline + diacylglycerol only at CDP-choline concentrations higher than 25 micromolar, pH 8, 10 min, 37°C, in presence of 0.0002% Tween 20, 1 mM EGTA, 5 mM MnCl2 Homo sapiens phosphatidylcholine + CMP - ? 400626 2.7.8.1 CDP-dimethylethanolamine + 1,2-diacylglycerol enzyme form Cpt1p Saccharomyces cerevisiae CMP + phosphatidyldimethylethanolamine - ? 379559 2.7.8.1 CDP-ethanolamine + 1,2-diacyl-sn-glycerol - Homo sapiens CMP + a phosphatidylethanolamine - r 436423 2.7.8.1 CDP-ethanolamine + 1,2-diacyl-sn-glycerol - Drosophila melanogaster CMP + a phosphatidylethanolamine - r 436423 2.7.8.1 CDP-ethanolamine + 1,2-diacyl-sn-glycerol - Glycine max CMP + a phosphatidylethanolamine - ? 436423 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Gallus gallus CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Rattus norvegicus CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Rattus norvegicus CMP + a phosphatidylethanolamine - r 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Saccharomyces cerevisiae CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Bos taurus CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Oryctolagus cuniculus CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Pisum sativum CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Solanum tuberosum CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Glycine max CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Glycine max CMP + a phosphatidylethanolamine - r 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Ricinus communis CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Mesocricetus auratus CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Mesocricetus auratus CMP + a phosphatidylethanolamine - r 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Tetrahymena thermophila CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Arabidopsis thaliana CMP + a phosphatidylethanolamine - r 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Chlamydomonas reinhardtii CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol - Rattus norvegicus CMP + a phosphatidylethanolamine 1,2-diacyl-sn-glycero-3-phosphorylethanolamine ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol preferred substrates in decreasing order: di-18:1 diacylglycerol, di-16:1 diacylglycerol, 16:0/18:1 diacylglycerol, 16:0/22:6 diacylglycerol Homo sapiens CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol preferred substrates: 16:0/18:1 diacylglycerol, di-18:1 diacylglycerol Homo sapiens CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol in presence of 5'-CMP Saccharomyces cerevisiae CMP + a phosphatidylethanolamine - r 359124 2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol enzyme specifically uses CDP-ethanolamine as the phosphobase donor Homo sapiens CMP + a phosphatidylethanolamine - ? 359124 2.7.8.1 CDP-ethanolamine + 1,2-dioleoylglycerol - Rattus norvegicus CMP + dioleoylphosphatidylethanolamine - ? 359130 2.7.8.1 CDP-ethanolamine + 1,2-dioleoylglycerol - Saccharomyces cerevisiae CMP + dioleoylphosphatidylethanolamine - ? 359130 2.7.8.1 CDP-ethanolamine + 1,2-dioleoylglycerol highest activity Rattus norvegicus CMP + dioleoylphosphatidylethanolamine - ? 359130 2.7.8.1 CDP-ethanolamine + 1-alkyl-2-acyl-sn-glycerol - Rattus norvegicus CMP + 1-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine - ? 359125 2.7.8.1 CDP-ethanolamine + 1-arachidoyl-2-octadecenoylglycerol - Rattus norvegicus CMP + 1-arachidoyl-2-octadecenoylglycerophosphoethanolamine - r 452436 2.7.8.1 CDP-ethanolamine + 1-dodecanoyl-2-octadecenoylglycerol - Rattus norvegicus CMP + 1-dodecanoyl-2-octadecenoylglycerophosphoethanolamine - r 452437 2.7.8.1 CDP-ethanolamine + 1-heptadecanoyl-2-octadecenoylglycerol - Rattus norvegicus CMP + 1-heptadecanoyl-2-octadecenoylglycerophosphoethanolamine - r 452438 2.7.8.1 CDP-ethanolamine + 1-heptadecanoylglycerol - Rattus norvegicus CMP + ? - ? 359133 2.7.8.1 CDP-ethanolamine + 1-nonadecanoyl-2-octadecenoylglycerol - Rattus norvegicus CMP + 1-nonadecanoyl-2-octadecenoylglycerophosphoethanolamine - r 452439 2.7.8.1 CDP-ethanolamine + 1-O-alk-1'-enyl-2-acyl-sn-glycerol - Oryctolagus cuniculus CMP + 1-O-alk-1'-enyl-2-acyl-sn-glycerol-3-phosphorylethanolamine - ? 359139 2.7.8.1 CDP-ethanolamine + 1-octadecanoyl-2-octadecenoylglycerol - Rattus norvegicus CMP + 1-octadecanoyl-2-octadecenoylglycerophosphoethanolamine - r 452440 2.7.8.1 CDP-ethanolamine + 1-oleoyl-2-lauroylglycerol - Rattus norvegicus CMP + 1-oleoyl-2-lauroylphosphatidylethanolamine - ? 359136 2.7.8.1 CDP-ethanolamine + 1-oleoyl-2-palmitoylglycerol - Rattus norvegicus CMP + 1-oleoyl-2-palmitoylphosphatidylethanolamine - ? 359137 2.7.8.1 CDP-ethanolamine + 1-oleoyl-2-stearoyl-sn-glycerol - Rattus norvegicus CMP + 1-oleoyl-2-stearoyl-sn-glycerol-3-phosphorylethanolamine - ? 359138 2.7.8.1 CDP-ethanolamine + 1-pentadecanoyl-2-octadecenoylglycerol - Rattus norvegicus CMP + 1-pentadecanoyl-2-octadecenoylglycerophosphoethanolamine - r 452441 2.7.8.1 CDP-ethanolamine + 1-stearoyl-2-oleoylglycerol - Rattus norvegicus CMP + 1-stearoyl-2-oleoylphosphatidylethanolamine - ? 359131 2.7.8.1 CDP-ethanolamine + 1-stearoylglycerol - Rattus norvegicus CMP + ? - ? 359134 2.7.8.1 CDP-ethanolamine + 2-oleoylglycerol - Rattus norvegicus CMP + ? - ? 359135 2.7.8.1 CDP-ethanolamine + diacylglycerol - Homo sapiens phosphatidylethanolamine + CMP - ? 398832 2.7.8.1 CDP-ethanolamine + diacylglycerol pH 8, 10 min, 37°C, in presence of 0.0002% Tween 20, 1 mM EGTA, 5 mM MnCl2 Homo sapiens phosphatidylethanolamine + CMP reaction stop with 1:1 (v/v) mixture chloroform:methanol ? 398832 2.7.8.1 CDP-ethanolamine + dipalmitoylglycerol - Rattus norvegicus CMP + dipalmitoylphosphatidylethanolamine - ? 359132 2.7.8.1 CDP-monomethylethanolamine + 1,2-diacylglycerol CDP-monomethylethanolamine is the preferred substrate for enzyme form Ept1p Saccharomyces cerevisiae CMP + phosphatidylmonomethylethanolamine - ? 379561 2.7.8.1 CDP-propanolamine + 1,2-diacylglycerol - Saccharomyces cerevisiae CMP + phosphatidylpropanolamine - ? 379562 2.7.8.1 lysophosphatidylcholine + CMP 75% of the activity with phosphatidylethanolamine Mesocricetus auratus ? - r 359128 2.7.8.1 lysophosphatidylethanolamine + CMP 74% of the activity with phosphatidylethanolamine Mesocricetus auratus ? - r 359129 2.7.8.1 additional information - Gallus gallus ? - ? 89 2.7.8.1 additional information - Saccharomyces cerevisiae ? - ? 89 2.7.8.1 additional information 1,2-diacylglycerols containing fatty acids 6, 12 and 14 carbons in length are no substrates Rattus norvegicus ? - ? 89 2.7.8.1 additional information enzyme selects 1-palmitoyl-2-linoleoyldiacylglycerol as a preferred substrate Pisum sativum ? - ? 89 2.7.8.1 additional information enzyme selects 1-palmitoyl-2-linoleoyldiacylglycerol as a preferred substrate Glycine max ? - ? 89 2.7.8.1 additional information distinctly higher reaction rates with the combined 1-saturated 2-docosahexaenoyl precursors as compared to the corresponding monoenoic, dienoic or tetraenoic substrates, a selectivity towards 1-stearoyl-2-arachidonoyl and 1-stearoyl-2-oleoyl diacylglycerols over their 1-palmitoyl homologues Rattus norvegicus ? - ? 89 2.7.8.1 additional information lung enzyme is relatively nonselective, the concentration of diacylglycerol and the physical state in which it is presented to the enzyme can effect the apparent selectivity of the enzyme for diacylglycerols Rattus norvegicus ? - ? 89 2.7.8.1 additional information 16 fold selectivity for 1-O-alk-1-enyl-2-acyl-sn-glycerol, the primary determinant of substrate selectivity is the covalent nature of the sn-1 aliphatic group of diradyl glycerol acceptors Oryctolagus cuniculus ? - ? 89 2.7.8.1 additional information broad substrate specificity, overview Rattus norvegicus ? - ? 89 2.7.8.1 additional information broad substrate specificity, overview Saccharomyces cerevisiae ? - ? 89 2.7.8.1 additional information broad substrate specificity, overview Glycine max ? - ? 89 2.7.8.1 additional information broad substrate specificity, overview Mesocricetus auratus ? - ? 89 2.7.8.1 additional information substrate specificity overview Rattus norvegicus ? - ? 89 2.7.8.1 additional information several 1-oleoyl-2-saturated types of diacylglycerol are effectively used Rattus norvegicus ? - ? 89 2.7.8.1 additional information fully saturated diacylglycerols like dipalmitoylglycerol are poorly utilized Rattus norvegicus ? - ? 89 2.7.8.1 additional information 1-acyl-2-oleoylglycerols ranging from 1-lauroyl to 1-heptadecanoyl species: 1-heptadecanoyl and 1-stearoyl species used most actively Rattus norvegicus ? - ? 89 2.7.8.1 additional information overview: utilization of endogenous phospholipids in the reverse reaction Rattus norvegicus ? - ? 89 2.7.8.1 additional information no discrimination towards the molecular species of endogenous pool of diacylglycerols Solanum tuberosum ? - ? 89 2.7.8.1 additional information significant selectivity which may be of considerable importance in maintaining the characteristic composition of fatty acyl chains in membrane phospholipids Rattus norvegicus ? - ? 89 2.7.8.1 additional information metabolic pathway for the synthesis of 1-alk-1-enyl-2-acyl-sn-glycero-3-phosphorylethanolamine Rattus norvegicus ? - ? 89 2.7.8.1 additional information catalyzes the final step in synthesis of phosphatidylethanolamine Mesocricetus auratus ? - ? 89 2.7.8.1 additional information nonessential enzyme Saccharomyces cerevisiae ? - ? 89 2.7.8.1 additional information reversibility of phosphoethanolamine transferase and phosphocholine transferase permits the interconversion of the diacylglycerol moieties of choline and ethanolamine glycerophospholipids Rattus norvegicus ? - ? 89 2.7.8.1 additional information glycerophospholipid synthesis is very active in G2/M phase of MCF-7 cells Homo sapiens ? - ? 89 2.7.8.1 additional information CDP-ethanolamine-specific activity Homo sapiens ? - ? 89 2.7.8.1 additional information the enzyme has dual specificity for both CDP-choline, EC 2.7.8.2, and CDP-ethanolamine Homo sapiens ? - ? 89 2.7.8.1 phosphatidylcholine + CMP - Rattus norvegicus CDP-choline + diacylglycerol - ? 359126 2.7.8.1 phosphatidylcholine + CMP - Glycine max CDP-choline + diacylglycerol - r 359126 2.7.8.1 phosphatidylcholine + CMP - Arabidopsis thaliana CDP-choline + diacylglycerol - r 359126 2.7.8.1 phosphatidylcholine + CMP 88% of the activity with phosphatidylethanolamine Mesocricetus auratus CDP-choline + diacylglycerol - r 359126