2.5.1.58 (1E)-1-[(2E,6E,10E)-12-azido-3,7,11-trimethyldodeca-2,6,10-trien-1-ylidene]-2-oxodiphosphane + protein-cysteine - Saccharomyces cerevisiae ? - ? 395037 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407477 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407478 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407479 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(prop-2-yn-1-yloxy)octa-2,6-dien-1-yl diphosphate + CCIQ - Rattus norvegicus ? - ? 436591 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(prop-2-yn-1-yloxy)octa-2,6-dien-1-yl diphosphate + CGGDD - Rattus norvegicus ? - ? 436592 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(prop-2-yn-1-yloxy)octa-2,6-dien-1-yl diphosphate + CSVL - Rattus norvegicus ? - ? 436593 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(prop-2-yn-1-yloxy)octa-2,6-dien-1-yl diphosphate + CTIQ - Rattus norvegicus ? - ? 436594 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(prop-2-yn-1-yloxy)octa-2,6-dien-1-yl diphosphate + CVIS - Rattus norvegicus ? - ? 436595 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(prop-2-yn-1-yloxy)octa-2,6-dien-1-yl diphosphate + CVLL - Rattus norvegicus ? - ? 436596 2.5.1.58 (2E,6E)-3,7-dimethyl-8-(prop-2-yn-1-yloxy)octa-2,6-dien-1-yl diphosphate + CVLS - Rattus norvegicus ? - ? 436597 2.5.1.58 (2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407480 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407481 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(3,4,5-trimethoxybenzyl)oxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(3,4,5-trimethoxybenzyl)oxy]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407482 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407483 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407484 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-y)CVLS + diphosphate - ? 407485 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407486 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407487 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407488 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407489 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407490 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407491 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407492 2.5.1.58 (2E,6E)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl)CVLS + diphosphate - ? 407493 2.5.1.58 (2E,6E)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl)CVLS + diphosphate - ? 407494 2.5.1.58 (2E,6E)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407495 2.5.1.58 (2E,6E)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407496 2.5.1.58 (2E,6E)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407497 2.5.1.58 (2E,6E)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407498 2.5.1.58 (2E,6E)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yll)CVLS + diphosphate - ? 407499 2.5.1.58 (2E,6E)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407500 2.5.1.58 (2E,6E)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407501 2.5.1.58 (2E,6E)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407502 2.5.1.58 (2E,6E)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407503 2.5.1.58 (2E,6E)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407504 2.5.1.58 (2E,6E)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407505 2.5.1.58 (2E,6E)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407506 2.5.1.58 (2E,6E)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407507 2.5.1.58 (2E,6E)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yll)CVLS + diphosphate - ? 407508 2.5.1.58 (2E,6E)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407509 2.5.1.58 (2E,6E)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407510 2.5.1.58 (2E,6E)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407511 2.5.1.58 (2E,6E)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407512 2.5.1.58 (2E,6E)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407513 2.5.1.58 (2E,6E)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yll)CVLS + diphosphate - ? 407514 2.5.1.58 (2E,6E)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407515 2.5.1.58 (2E,6E)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407516 2.5.1.58 (2E,6E)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407517 2.5.1.58 (2E,6E)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407518 2.5.1.58 (2E,6E)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407519 2.5.1.58 (2E,6E)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407520 2.5.1.58 (2E,6E)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407521 2.5.1.58 (2E,6E)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407522 2.5.1.58 (2E,6E)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407523 2.5.1.58 (2E,6E)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407524 2.5.1.58 (2E,6E)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407525 2.5.1.58 (2E,6E)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407526 2.5.1.58 (2E,6E)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407527 2.5.1.58 (2E,6E)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407528 2.5.1.58 (2E,6E)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407529 2.5.1.58 (2E,6E)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407530 2.5.1.58 (2E,6E)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407531 2.5.1.58 (2E,6E)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407532 2.5.1.58 (2E,6E)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407533 2.5.1.58 (2E,6E)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl)CVLS + diphosphate - ? 407534 2.5.1.58 (2E,6E)-farnesyl diphosphate + (protein)-L-cysteine - Rattus norvegicus S-(2E,6E)-farnesyl protein + diphosphate - ? 436199 2.5.1.58 (2E,6E)-farnesyl diphosphate + (protein)-L-cysteine - Homo sapiens S-(2E,6E)-farnesyl protein + diphosphate - ? 436199 2.5.1.58 (2E,6E)-farnesyl diphosphate + (protein)-L-cysteine - Saccharomyces cerevisiae S-(2E,6E)-farnesyl protein + diphosphate - ? 436199 2.5.1.58 (2E,6E)-farnesyl diphosphate + CCIQ - Rattus norvegicus S-(2E,6E)-farnesyl-CCIQ + diphosphate - ? 436598 2.5.1.58 (2E,6E)-farnesyl diphosphate + CGGDD - Rattus norvegicus S-(2E,6E)-farnesyl-CGGDD + diphosphate - ? 436599 2.5.1.58 (2E,6E)-farnesyl diphosphate + CSVL - Rattus norvegicus S-(2E,6E)-farnesyl-CSVL + diphosphate - ? 436600 2.5.1.58 (2E,6E)-farnesyl diphosphate + CTIQ - Rattus norvegicus S-(2E,6E)-farnesyl-CTIQ + diphosphate - ? 436601 2.5.1.58 (2E,6E)-farnesyl diphosphate + CVIS - Rattus norvegicus S-(2E,6E)-farnesyl-CVIS + diphosphate - ? 436602 2.5.1.58 (2E,6E)-farnesyl diphosphate + CVLL - Rattus norvegicus S-(2E,6E)-farnesyl-CVLL + diphosphate - ? 436603 2.5.1.58 (2E,6E)-farnesyl diphosphate + CVLS - Rattus norvegicus S-(2E,6E)-farnesyl-CVLS + diphosphate - ? 436604 2.5.1.58 (2E,6E)-farnesyl diphosphate + dansyl-CGVLS assay at pH 7.5, 37°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLS - ? 407546 2.5.1.58 (2E,6E)-farnesyl diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLS + diphosphate - ? 407547 2.5.1.58 (2E,6E)-farnesyl diphosphate + dansyl-GCVLS assay at pH 7.5, 30°C Saccharomyces cerevisiae dansyl-G-(S-(2E,6E)-farnesyl)CVLS + diphosphate - ? 407547 2.5.1.58 (2E,6E)-farnesyl diphosphate + K Ras-cysteine - Rattus norvegicus S-(2E,6E)-farnesyl-[K Ras]-L-cysteine + diphosphate - ? 436605 2.5.1.58 (2E,6E)-farnesyl diphosphate + KGCVIM - Aspergillus fumigatus S-(2E,6E)-farnesyl-KGCVIM + diphosphate - ? 436606 2.5.1.58 (2E,6E)-farnesyl diphosphate + KGCVVM - Aspergillus fumigatus S-(2E,6E)-farnesyl-KGCVVM + diphosphate - ? 436607 2.5.1.58 (2E,6E)-farnesyl diphosphate + [H Ras]-L-cysteine - Rattus norvegicus S-(2E,6E)-farnesyl-[H Ras]-L-cysteine + diphosphate - ? 436201 2.5.1.58 (2E,6E)-farnesyl diphosphate + [H Ras]-L-cysteine - Homo sapiens S-(2E,6E)-farnesyl-[H Ras]-L-cysteine + diphosphate - ? 436201 2.5.1.58 (2E,6E)-farnesyl diphosphate + [K Ras]-L-cysteine - Rattus norvegicus S-(2E,6E)-farnesyl-[K Ras]-L-cysteine + diphosphate - ? 436202 2.5.1.58 (2E,6E)-farnesyl diphosphate + [K Ras]-L-cysteine - Homo sapiens S-(2E,6E)-farnesyl-[K Ras]-L-cysteine + diphosphate - ? 436202 2.5.1.58 (2E,6E)-farnesyl diphosphate + [N Ras]-L-cysteine - Rattus norvegicus S-(2E,6E)-farnesyl-[N Ras]-L-cysteine + diphosphate - ? 436203 2.5.1.58 (2E,6E)-farnesyl diphosphate + [N Ras]-L-cysteine - Homo sapiens S-(2E,6E)-farnesyl-[N Ras]-L-cysteine + diphosphate - ? 436203 2.5.1.58 (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine assay at pH 7.5, 30°C Homo sapiens [protein]-S-((2E,6E)-farnesyl)-L-cysteine + diphosphate - ? 407553 2.5.1.58 (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine - Homo sapiens S-(2E,6E)-farnesyl-[protein]-L-cysteine + diphosphate - ? 436204 2.5.1.58 (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine - Trypanosoma brucei S-(2E,6E)-farnesyl-[protein]-L-cysteine + diphosphate - ? 436204 2.5.1.58 (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine - Aspergillus fumigatus S-(2E,6E)-farnesyl-[protein]-L-cysteine + diphosphate - ? 436204 2.5.1.58 (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine - Candida albicans S-(2E,6E)-farnesyl-[protein]-L-cysteine + diphosphate - ? 436204 2.5.1.58 (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine - Rattus norvegicus S-(2E,6E)-farnesyl-[protein]-L-cysteine + diphosphate - ? 436204 2.5.1.58 (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine the reaction is catalyzed by protein farnesyltransferase on protein substrates bearing the C-terminal CaaX motif Aspergillus fumigatus S-(2E,6E)-farnesyl-[protein]-L-cysteine + diphosphate - ? 436204 2.5.1.58 (2E,6E)-farnesyl diphosphate + [Rho]-L-cysteine - Rattus norvegicus S-(2E,6E)-farnesyl-[Rho]-L-cysteine + diphosphate - ? 436205 2.5.1.58 (2E,6E)-farnesyl diphosphate + [Rho]-L-cysteine - Homo sapiens S-(2E,6E)-farnesyl-[Rho]-L-cysteine + diphosphate - ? 436205 2.5.1.58 (2E,6E,10E)-3,7,11-trimethyl-12-(prop-2-yn-1-yloxy)dodeca-2,6,10-trien-1-yl diphosphate + CCIQ - Rattus norvegicus ? - ? 436608 2.5.1.58 (2E,6E,10E)-3,7,11-trimethyl-12-(prop-2-yn-1-yloxy)dodeca-2,6,10-trien-1-yl diphosphate + CGGDD - Rattus norvegicus ? - ? 436609 2.5.1.58 (2E,6E,10E)-3,7,11-trimethyl-12-(prop-2-yn-1-yloxy)dodeca-2,6,10-trien-1-yl diphosphate + CSVL - Rattus norvegicus ? - ? 436610 2.5.1.58 (2E,6E,10E)-3,7,11-trimethyl-12-(prop-2-yn-1-yloxy)dodeca-2,6,10-trien-1-yl diphosphate + CTIQ - Rattus norvegicus ? - ? 436611 2.5.1.58 (2E,6E,10E)-3,7,11-trimethyl-12-(prop-2-yn-1-yloxy)dodeca-2,6,10-trien-1-yl diphosphate + CVIS - Rattus norvegicus ? - ? 436612 2.5.1.58 (2E,6E,10E)-3,7,11-trimethyl-12-(prop-2-yn-1-yloxy)dodeca-2,6,10-trien-1-yl diphosphate + CVLL - Rattus norvegicus ? - ? 436613 2.5.1.58 (2E,6E,10E)-3,7,11-trimethyl-12-(prop-2-yn-1-yloxy)dodeca-2,6,10-trien-1-yl diphosphate + CVLS - Rattus norvegicus ? - ? 436614 2.5.1.58 (2E,6Z)-3,11-dimethyl-7-(prop-2-yn-1-yl)dodeca-2,6,10-trien-1-yl diphosphate + CCIQ - Rattus norvegicus ? - ? 436615 2.5.1.58 (2E,6Z)-3,11-dimethyl-7-(prop-2-yn-1-yl)dodeca-2,6,10-trien-1-yl diphosphate + CGGDD - Rattus norvegicus ? - ? 436616 2.5.1.58 (2E,6Z)-3,11-dimethyl-7-(prop-2-yn-1-yl)dodeca-2,6,10-trien-1-yl diphosphate + CSVL - Rattus norvegicus ? - ? 436617 2.5.1.58 (2E,6Z)-3,11-dimethyl-7-(prop-2-yn-1-yl)dodeca-2,6,10-trien-1-yl diphosphate + CTIQ - Rattus norvegicus ? - ? 436618 2.5.1.58 (2E,6Z)-3,11-dimethyl-7-(prop-2-yn-1-yl)dodeca-2,6,10-trien-1-yl diphosphate + CVIS - Rattus norvegicus ? - ? 436619 2.5.1.58 (2E,6Z)-3,11-dimethyl-7-(prop-2-yn-1-yl)dodeca-2,6,10-trien-1-yl diphosphate + CVLL - Rattus norvegicus ? - ? 436620 2.5.1.58 (2E,6Z)-3,11-dimethyl-7-(prop-2-yn-1-yl)dodeca-2,6,10-trien-1-yl diphosphate + CVLS - Rattus norvegicus ? - ? 436621 2.5.1.58 (2E,6Z)-7-(but-3-yn-1-yl)-3,11-dimethyldodeca-2,6,10-trien-1-yl diphosphate + CCIQ - Rattus norvegicus ? - ? 436622 2.5.1.58 (2E,6Z)-7-(but-3-yn-1-yl)-3,11-dimethyldodeca-2,6,10-trien-1-yl diphosphate + CGGDD - Rattus norvegicus ? - ? 436623 2.5.1.58 (2E,6Z)-7-(but-3-yn-1-yl)-3,11-dimethyldodeca-2,6,10-trien-1-yl diphosphate + CSVL - Rattus norvegicus ? - ? 436624 2.5.1.58 (2E,6Z)-7-(but-3-yn-1-yl)-3,11-dimethyldodeca-2,6,10-trien-1-yl diphosphate + CTIQ - Rattus norvegicus ? - ? 436625 2.5.1.58 (2E,6Z)-7-(but-3-yn-1-yl)-3,11-dimethyldodeca-2,6,10-trien-1-yl diphosphate + CVIS - Rattus norvegicus ? - ? 436626 2.5.1.58 (2E,6Z)-7-(but-3-yn-1-yl)-3,11-dimethyldodeca-2,6,10-trien-1-yl diphosphate + CVLL - Rattus norvegicus ? - ? 436627 2.5.1.58 (2E,6Z)-7-(but-3-yn-1-yl)-3,11-dimethyldodeca-2,6,10-trien-1-yl diphosphate + CVLS - Rattus norvegicus ? - ? 436628 2.5.1.58 (2Z)-geranylgeranyl diphosphate + protein cysteine - Homo sapiens diphosphate + S-(2Z)-geranylgeranylcysteinyl protein - ? 386861 2.5.1.58 10-benzyloxy-3-methyl-2-decen-1-ol-diphosphate + N-dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus diphosphate + N-dansyl-Gly-S-(10-benzyloxy-3-methyl-2-decenyl)-Cys-Val-Leu-Ser - ? 354410 2.5.1.58 12-propargoxyfarnesyl diphosphate + N-dansyl-Gly-Cys-Val-Ile-Ala-OH - Saccharomyces cerevisiae diphosphate + propargoxyfarnesyl N-dansyl-Gly-Cys-Val-Ile-Ala-OH - ? 395312 2.5.1.58 3-(3-methyl-2-butenyl)-7,11-dimethyldodeca-2(Z),6(E),10-triene 1-diphosphate + dansyl-Gly-Cys-Lys-Thr-Gln - Rattus norvegicus ? + diphosphate - ? 375790 2.5.1.58 3-(3-methyl-2-butenyl)-7,11-dimethyldodeca-2(Z),6(E),10-triene 1-diphosphate + dansyl-Gly-Cys-Lys-Val-Leu - Rattus norvegicus ? + diphosphate - ? 375791 2.5.1.58 3-(3-methyl-2-butenyl)-7,11-dimethyldodeca-2(Z),6(E),10-triene 1-diphosphate + dansyl-Gly-Cys-Val-Ile-Met - Rattus norvegicus ? + diphosphate - ? 375792 2.5.1.58 3-(3-methyl-2-butenyl)-7,11-dimethyldodeca-2(Z),6(E),10-triene 1-diphosphate + dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus ? + diphosphate - ? 375793 2.5.1.58 3-(azidomethyl)-N-[(2E,6E,8E)-2,6-dimethyl-8-(oxodiphosphanylidene)octa-2,6-dien-1-yl]aniline + protein-cysteine - Saccharomyces cerevisiae ? - ? 395699 2.5.1.58 3-(azidomethyl)-N-[(4E,8E,10E)-4,8-dimethyl-10-(oxodiphosphanylidene)deca-4,8-dien-1-yl]aniline + protein-cysteine - Saccharomyces cerevisiae ? - ? 395700 2.5.1.58 6-benzyloxy-3-methyl-2-hexen-1-ol-diphosphate + N-dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus diphosphate + N-dansyl-Gly-S-(6-benzyloxy-3-methyl-2-hexenyl)-Cys-Val-Leu-Ser - ? 354406 2.5.1.58 7-benzyloxy-3-methyl-2-hepten-1-ol-diphosphate + N-dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus diphosphate + N-dansyl-Gly-S-(7-benzyloxy-3-methyl-2-heptenyl)-Cys-Val-Leu-Ser - ? 354407 2.5.1.58 8-benzyloxy-3-methyl-2-octen-1-ol-diphosphate + N-dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus diphosphate + N-dansyl-Gly-S-(8-benzyloxy-3-methyl-2-octenyl)-Cys-Val-Leu-Ser - ? 354408 2.5.1.58 9-benzyloxy-3-methyl-2-nonen-1-ol-diphosphate + N-dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus diphosphate + N-dansyl-Gly-S-(9-benzyloxy-3-methyl-2-nonenyl)-Cys-Val-Leu-Ser - ? 354409 2.5.1.58 AAA-GPP + N-dansyl-GCVLS - Homo sapiens ? - ? 396132 2.5.1.58 APO-GPP + N-dansyl-GCVLS - Homo sapiens ? - ? 396422 2.5.1.58 CALQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CALQ + diphosphate - ? 408816 2.5.1.58 CALV + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CALV + diphosphate - ? 408817 2.5.1.58 CAVQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CAVQ + diphosphate - ? 408824 2.5.1.58 CCIF + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CCIF + diphosphate - ? 408825 2.5.1.58 CCIL + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CCIL + diphosphate - ? 408826 2.5.1.58 CDVK + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CDVK + diphosphate - ? 408827 2.5.1.58 CEIQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CEIQ + diphosphate - ? 408828 2.5.1.58 CFLS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CFLS + diphosphate - ? 408832 2.5.1.58 CFPS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CFPS + diphosphate - ? 408833 2.5.1.58 CFTN + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CFTN + diphosphate - ? 408834 2.5.1.58 CFVN + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CFVN + diphosphate - ? 408835 2.5.1.58 CGIA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CGIA + diphosphate - ? 408836 2.5.1.58 CGIM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CGIM + diphosphate - ? 408837 2.5.1.58 CGLF + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CGLF + diphosphate - ? 408838 2.5.1.58 CGLY + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CGLY + diphosphate - ? 408839 2.5.1.58 CGVV + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CGVV + diphosphate - ? 408840 2.5.1.58 CHIM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CHIM + diphosphate - ? 408843 2.5.1.58 CHIQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CHIQ + diphosphate - ? 408844 2.5.1.58 CHLM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CHLM + diphosphate - ? 408845 2.5.1.58 CHLS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CHLS + diphosphate - ? 408851 2.5.1.58 CHVM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CHVM + diphosphate - ? 408867 2.5.1.58 CHVQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CHVQ + diphosphate - ? 408868 2.5.1.58 CIVA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CIVA + diphosphate - ? 408873 2.5.1.58 CKIF + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CKIF + diphosphate - ? 408874 2.5.1.58 CKIS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CKIS + diphosphate - ? 408876 2.5.1.58 CKIV + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CKIV + diphosphate - ? 408877 2.5.1.58 CLIT + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CLIT + diphosphate - ? 408879 2.5.1.58 CLLM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CLLM + diphosphate - ? 408880 2.5.1.58 CLLV + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CLLV + diphosphate - ? 408881 2.5.1.58 CLML + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CLML + diphosphate - ? 408882 2.5.1.58 CLTS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CLTS + diphosphate - ? 408883 2.5.1.58 CLVM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CLVM + diphosphate - ? 408884 2.5.1.58 CNIM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CNIM + diphosphate - ? 408896 2.5.1.58 CNLF + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CNLF + diphosphate - ? 408897 2.5.1.58 CNLK + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CNLK + diphosphate - ? 408898 2.5.1.58 CNLM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CNLM + diphosphate - ? 408899 2.5.1.58 CNLQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CNLQ + diphosphate - ? 408900 2.5.1.58 CQTA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CQTA + diphosphate - ? 408907 2.5.1.58 CRIS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CRIS + diphosphate - ? 408908 2.5.1.58 CSFM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSFM + diphosphate - ? 408911 2.5.1.58 CSIM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSIM + diphosphate - ? 408912 2.5.1.58 CSIS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSIS + diphosphate - ? 408913 2.5.1.58 CSLA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSLA + diphosphate - ? 408914 2.5.1.58 CSLC + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSLC + diphosphate - ? 408915 2.5.1.58 CSLG + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSLG + diphosphate - ? 408916 2.5.1.58 CSLH + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSLH + diphosphate - ? 408917 2.5.1.58 CSLM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSLM + diphosphate - ? 408918 2.5.1.58 CSVQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSVQ + diphosphate - ? 408919 2.5.1.58 CSVS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CSVS + diphosphate - ? 408920 2.5.1.58 CTII + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTII + diphosphate - ? 408921 2.5.1.58 CTIV + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTIV + diphosphate - ? 408922 2.5.1.58 CTKF + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTKF + diphosphate - ? 408923 2.5.1.58 CTLA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTLA + diphosphate - ? 408924 2.5.1.58 CTLM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTLM + diphosphate - ? 408925 2.5.1.58 CTLQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTLQ + diphosphate - ? 408926 2.5.1.58 CTMS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTMS + diphosphate - ? 408927 2.5.1.58 CTTQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTTQ + diphosphate - ? 408930 2.5.1.58 CTVF + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTVF + diphosphate - ? 408931 2.5.1.58 CTVS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTVS + diphosphate - ? 408932 2.5.1.58 CTVV + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CTVV + diphosphate - ? 408933 2.5.1.58 CVHF + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CVHF + diphosphate - ? 408935 2.5.1.58 CVLA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CVLA + diphosphate - ? 408936 2.5.1.58 CVLH + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CVLH + diphosphate - ? 408937 2.5.1.58 CVLQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CVLQ + diphosphate - ? 408938 2.5.1.58 CVQM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CVQM + diphosphate - ? 408939 2.5.1.58 CVVT + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CVVT + diphosphate - ? 408940 2.5.1.58 CYIS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CYIS + diphosphate - ? 409114 2.5.1.58 CYLA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CYLA + diphosphate - ? 409115 2.5.1.58 CYPD + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CYPD + diphosphate - ? 409116 2.5.1.58 CYVM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus S-(2E,6E)-farnesyl-CYVM + diphosphate - ? 409123 2.5.1.58 dansyl-GCVAA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVAA + diphosphate - ? 409185 2.5.1.58 dansyl-GCVAM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVAM + diphosphate - ? 409186 2.5.1.58 dansyl-GCVAQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVAQ + diphosphate - ? 409187 2.5.1.58 dansyl-GCVAS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVAS + diphosphate - ? 409188 2.5.1.58 dansyl-GCVCA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVCA + diphosphate - ? 409189 2.5.1.58 dansyl-GCVCM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVCM + diphosphate - ? 409190 2.5.1.58 dansyl-GCVCQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVCQ + diphosphate - ? 409191 2.5.1.58 dansyl-GCVCS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVCS + diphosphate - ? 409192 2.5.1.58 dansyl-GCVDA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVDA + diphosphate - ? 409193 2.5.1.58 dansyl-GCVDM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVDM + diphosphate - ? 409194 2.5.1.58 dansyl-GCVDQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVDQ + diphosphate - ? 409195 2.5.1.58 dansyl-GCVDS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVDS + diphosphate - ? 409196 2.5.1.58 dansyl-GCVDS + (2E,6E)-farnesyl diphosphate poor substrate for wild-type Homo sapiens dansyl-G-(S-(2E,6E)-farnesyl)CVDS + diphosphate - ? 409196 2.5.1.58 dansyl-GCVEA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVEA + diphosphate - ? 409197 2.5.1.58 dansyl-GCVEM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVEM + diphosphate - ? 409198 2.5.1.58 dansyl-GCVEQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVEQ + diphosphate - ? 409199 2.5.1.58 dansyl-GCVES + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVES + diphosphate - ? 409200 2.5.1.58 dansyl-GCVFA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVFA + diphosphate - ? 409201 2.5.1.58 dansyl-GCVFM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVFM + diphosphate - ? 409202 2.5.1.58 dansyl-GCVFQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVFQ + diphosphate - ? 409203 2.5.1.58 dansyl-GCVFS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVFS + diphosphate - ? 409204 2.5.1.58 dansyl-GCVGA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVGA + diphosphate - ? 409205 2.5.1.58 dansyl-GCVGM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVGM + diphosphate - ? 409206 2.5.1.58 dansyl-GCVGQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVGQ + diphosphate - ? 409207 2.5.1.58 dansyl-GCVGS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVGS + diphosphate - ? 409208 2.5.1.58 dansyl-GCVHA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVHA + diphosphate - ? 409209 2.5.1.58 dansyl-GCVHM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVHM + diphosphate - ? 409210 2.5.1.58 dansyl-GCVHQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVHQ + diphosphate - ? 409211 2.5.1.58 dansyl-GCVHS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVHS + diphosphate - ? 409212 2.5.1.58 dansyl-GCVIA + (2E,6E)-farnesyl diphosphate 100% enzyme activity, specific activity 0.765 microM/min Saccharomyces cerevisiae dansyl-G-(S-(2E,6E)-farnesyl)CVIA + diphosphate - ? 409213 2.5.1.58 dansyl-GCVIA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVIA + diphosphate - ? 409213 2.5.1.58 dansyl-GCVIA + 1-(4,5-dimethoxy-nitrophenyl)ethyl (2E,6E)-farnesyl diphosphate 7.6% enzyme activity, specific activity 0.058 microM/min Saccharomyces cerevisiae ? - ? 409214 2.5.1.58 dansyl-GCVIA + 2-nitrophenyl (2E,6E)-farnesyl diphosphate 14% enzyme activity, specific activity 0.104 microM/min Saccharomyces cerevisiae ? - ? 409215 2.5.1.58 dansyl-GCVIM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVIM + diphosphate - ? 409216 2.5.1.58 dansyl-GCVIQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVIQ + diphosphate - ? 409217 2.5.1.58 dansyl-GCVIS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVIS + diphosphate - ? 409218 2.5.1.58 dansyl-GCVKA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVKA + diphosphate - ? 409219 2.5.1.58 dansyl-GCVKLQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLQ + diphosphate - ? 409220 2.5.1.58 dansyl-GCVKM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVKM + diphosphate - ? 409221 2.5.1.58 dansyl-GCVKQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVKQ + diphosphate - ? 409222 2.5.1.58 dansyl-GCVKS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVKS + diphosphate - ? 409223 2.5.1.58 dansyl-GCVKS + (2E,6E)-farnesyl diphosphate poor substrate for wild-type Homo sapiens dansyl-G-(S-(2E,6E)-farnesyl)CVKS + diphosphate - ? 409223 2.5.1.58 dansyl-GCVLA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLA + diphosphate - ? 409224 2.5.1.58 dansyl-GCVLM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLM + diphosphate - ? 409225 2.5.1.58 dansyl-GCVLS + (2E,6E)-farnesyl diphosphate - Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLS + diphosphate - ? 409226 2.5.1.58 dansyl-GCVLS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVLS + diphosphate - ? 409226 2.5.1.58 dansyl-GCVLS + (E)-[4-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]phenyl]-methanyl diphosphate - Rattus norvegicus dansyl-G-(S-(E)-[4-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]phenyl]-methanyl)CVLS + diphosphate - ? 423281 2.5.1.58 dansyl-GCVLS + [3-[(3-phenoxyphenoxy)methyl]phenyl]-methanyl diphosphate - Rattus norvegicus dansyl-G-(S-[3-[(3-phenoxyphenoxy)methyl]phenyl]-methanyl)CVLS + diphosphate - ? 423282 2.5.1.58 dansyl-GCVMA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVMA + diphosphate - ? 409227 2.5.1.58 dansyl-GCVMM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVMM + diphosphate - ? 409228 2.5.1.58 dansyl-GCVMQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVMQ + diphosphate - ? 409229 2.5.1.58 dansyl-GCVMS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVMS + diphosphate - ? 409230 2.5.1.58 dansyl-GCVNA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVNA + diphosphate - ? 409231 2.5.1.58 dansyl-GCVNM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVNM + diphosphate - ? 409232 2.5.1.58 dansyl-GCVNQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVNQ + diphosphate - ? 409233 2.5.1.58 dansyl-GCVNS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVNS + diphosphate - ? 409234 2.5.1.58 dansyl-GCVPA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVPA + diphosphate - ? 409235 2.5.1.58 dansyl-GCVPM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVPM + diphosphate - ? 409236 2.5.1.58 dansyl-GCVPQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVPQ + diphosphate - ? 409237 2.5.1.58 dansyl-GCVPS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVPS + diphosphate - ? 409238 2.5.1.58 dansyl-GCVQA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVQA + diphosphate - ? 409239 2.5.1.58 dansyl-GCVQM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVQM + diphosphate - ? 409240 2.5.1.58 dansyl-GCVQQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVQQ + diphosphate - ? 409241 2.5.1.58 dansyl-GCVQs + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVQS + diphosphate - ? 409242 2.5.1.58 dansyl-GCVSA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVSA + diphosphate - ? 409243 2.5.1.58 dansyl-GCVSM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVSM + diphosphate - ? 409244 2.5.1.58 dansyl-GCVSQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVSQ + diphosphate - ? 409245 2.5.1.58 dansyl-GCVSS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVSS + diphosphate - ? 409246 2.5.1.58 dansyl-GCVTA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVTA + diphosphate - ? 409247 2.5.1.58 dansyl-GCVTM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVTM + diphosphate - ? 409248 2.5.1.58 dansyl-GCVTQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVTQ + diphosphate - ? 409249 2.5.1.58 dansyl-GCVTS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVTS + diphosphate - ? 409250 2.5.1.58 dansyl-GCVVA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVVA + diphosphate - ? 409251 2.5.1.58 dansyl-GCVVM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVVM + diphosphate - ? 409252 2.5.1.58 dansyl-GCVVQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVVQ + diphosphate - ? 409253 2.5.1.58 dansyl-GCVVS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVVS + diphosphate - ? 409254 2.5.1.58 dansyl-GCVWA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVWA + diphosphate - ? 409255 2.5.1.58 dansyl-GCVWM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVWM + diphosphate - ? 409256 2.5.1.58 dansyl-GCVWQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVWQ + diphosphate - ? 409257 2.5.1.58 dansyl-GCVWS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVWS + diphosphate - ? 409258 2.5.1.58 dansyl-GCVYA + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVYA + diphosphate - ? 409259 2.5.1.58 dansyl-GCVYM + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVYM + diphosphate - ? 409260 2.5.1.58 dansyl-GCVYQ + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVYQ + diphosphate - ? 409261 2.5.1.58 dansyl-GCVYS + (2E,6E)-farnesyl diphosphate assay at pH 7.8, 25°C Rattus norvegicus dansyl-G-(S-(2E,6E)-farnesyl)CVYS + diphosphate - ? 409262 2.5.1.58 decadienyl azide diphosphate + protein-cysteine - Saccharomyces cerevisiae ? - ? 396971 2.5.1.58 farnesyl diphosphate + biotin-YRASNRSCAIM - Rattus norvegicus diphosphate + biotin-YRASNRS-(S-farnesyl)CAIM - ? 397152 2.5.1.58 farnesyl diphosphate + biotin-YRASNRSCAIM - Plasmodium falciparum diphosphate + biotin-YRASNRS-(S-farnesyl)CAIM - ? 397152 2.5.1.58 farnesyl diphosphate + dansyl-GCEV - Rattus norvegicus diphosphate + farnesyl dansyl-GCEV - ? 457957 2.5.1.58 farnesyl diphosphate + dansyl-GCFT - Rattus norvegicus diphosphate + farnesyl dansyl-GCFT - ? 457958 2.5.1.58 farnesyl diphosphate + dansyl-GCII - Rattus norvegicus diphosphate + farnesyl dansyl-GCII - ? 457959 2.5.1.58 farnesyl diphosphate + dansyl-GCLL - Rattus norvegicus diphosphate + farnesyl dansyl-GCLL - ? 457960 2.5.1.58 farnesyl diphosphate + dansyl-GCNV - Rattus norvegicus diphosphate + farnesyl dansyl-GCNV - ? 457961 2.5.1.58 farnesyl diphosphate + dansyl-GCQL - Rattus norvegicus diphosphate + farnesyl dansyl-GCQL - ? 457962 2.5.1.58 farnesyl diphosphate + dansyl-GCRL - Rattus norvegicus diphosphate + farnesyl dansyl-GCRL - ? 457963 2.5.1.58 farnesyl diphosphate + dansyl-GCSV - Rattus norvegicus diphosphate + farnesyl dansyl-GCSV - ? 457964 2.5.1.58 farnesyl diphosphate + dansyl-GCTV - Rattus norvegicus diphosphate + farnesyl dansyl-GCTV - ? 457965 2.5.1.58 farnesyl diphosphate + dansyl-GCVL - Rattus norvegicus diphosphate + farnesyl dansyl-GCVL - ? 457966 2.5.1.58 farnesyl diphosphate + dansyl-GCVLS - Saccharomyces cerevisiae diphosphate + S-farnesyl dansyl-GCVLS - ? 397154 2.5.1.58 farnesyl diphosphate + dansyl-GCVLS - Rattus norvegicus diphosphate + S-farnesyl dansyl-GCVLS - ? 397154 2.5.1.58 farnesyl diphosphate + dansyl-GCWI - Rattus norvegicus diphosphate + farnesyl dansyl-GCWI - ? 457967 2.5.1.58 farnesyl diphosphate + dansyl-GCYL - Rattus norvegicus diphosphate + farnesyl dansyl-GCYL - ? 457968 2.5.1.58 farnesyl diphosphate + dansyl-Gly-Cys-Lys-Thr-Gln - Rattus norvegicus dansyl-Gly-S-farnesyl-Cys-Lys-Thr-Gln + diphosphate - ? 376774 2.5.1.58 farnesyl diphosphate + dansyl-Gly-Cys-Lys-Val-Leu - Rattus norvegicus dansyl-Gly-S-farnesyl-Cys-Lys-Val-Leu + diphosphate - ? 376775 2.5.1.58 farnesyl diphosphate + dansyl-Gly-Cys-Val-Ile-Met - Rattus norvegicus dansyl-Gly-S-farnesyl-Cys-Val-Ile-Met + diphosphate - ? 376776 2.5.1.58 farnesyl diphosphate + dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus dansyl-Gly-S-farnesyl-Cys-Val-Leu-Ser + diphosphate - ? 376777 2.5.1.58 farnesyl diphosphate + Ds-GCVIA - Saccharomyces cerevisiae diphosphate + ? - ? 376778 2.5.1.58 farnesyl diphosphate + GCVLS - Escherichia coli Gly-S-farnesyl-Cys-Val-Leu-Ser + diphosphate - ? 376779 2.5.1.58 farnesyl diphosphate + GST-CIIL - Saccharomyces cerevisiae diphosphate + S-farnesyl-GST-Cys-Ile-Ile-Ser - ? 354413 2.5.1.58 farnesyl diphosphate + GST-CIIS GST-CIIS is glutathione S-transferase fused to the C-terminal 12 amino acids of yeast RAS2 protein Saccharomyces cerevisiae ? - ? 452210 2.5.1.58 farnesyl diphosphate + human recombinant wild-type H-Ras-CVLS - Entamoeba histolytica diphosphate + ? - ? 376780 2.5.1.58 farnesyl diphosphate + mutant H-Ras-CVLL 20fold less active than human recombinant wild-type H-Ras-CVLS Entamoeba histolytica diphosphate + ? - ? 376781 2.5.1.58 farnesyl diphosphate + N-dansyl-GCVLS assay at pH 7.5, 30°C Rattus norvegicus ? - ? 409396 2.5.1.58 farnesyl diphosphate + N-dansyl-GCVLS - Tripterygium wilfordii S-farnesyl-N-dansyl-GCVLS + diphosphate - ? 457969 2.5.1.58 farnesyl diphosphate + N-dansyl-Gly-Cys-Val-Leu-Ser the best substrate Rattus norvegicus diphosphate + N-dansyl-Gly-S-farnesyl-Cys-Val-Leu-Ser - ? 354404 2.5.1.58 farnesyl diphosphate + protein-cysteine - Mus musculus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Homo sapiens diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Homo sapiens diphosphate + S-farnesyl protein - ir 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Saccharomyces cerevisiae diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Nicotiana tabacum diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Plasmodium falciparum diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Leishmania amazonensis diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Catharanthus roseus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine the specific CAQQ motif of the ANJ1 protein has a low affinity for enzyme in vitro, enzyme specifically farnesylated the RasB-CVIM peptide substrate Solanum lycopersicum diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine posttranslational lipid modification in which a 15-carbon farnesyl isoprenoid is linked via a thioether bond to specific cysteine residues of proteins, the reactive cysteine is located in the C-terminal Ca1a2X motif in which C is the modified cysteine, a1 and a2 are often an aliphatic residue, and X is Ser, Met, Ala or Gln Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine posttranslational lipid modification in which a 15-carbon farnesyl isoprenoid is linked via a thioether bond to specific cysteine residues of proteins, the reactive cysteine is located in the C-terminal Ca1a2X motif in which C is the modified cysteine, a1 and a2 are often an aliphatic residue, and X is Ser, Met, Ala or Gln Bos taurus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine posttranslational lipid modification in which a 15-carbon farnesyl isoprenoid is linked via a thioether bond to specific cysteine residues of proteins, the reactive cysteine is located in the C-terminal Ca1a2X motif in which C is the modified cysteine, a1 and a2 are often an aliphatic residue, and X is Ser, Met, Ala or Gln Pisum sativum diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine Ha-Ras-CVLS, which is a good substrate for mammalian enzyme, not farnesylated by the parasite enzyme, only the mammalian enzyme substrate RAS1-CVIM farnesylated by parasite enzyme Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine Ha-Ras-CVLS, which is a good substrate for mammalian enzyme, not farnesylated by the parasite enzyme, only the mammalian enzyme substrate RAS1-CVIM farnesylated by parasite enzyme Trypanosoma brucei brucei diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine substrate are: Ras superfamiliy and Ras-related proteins for example Rap, Rab, Rac and Ral, large G proteins, nuclear lamins, rhodopsin kinase and the retinal cGMP phosphodiesterase Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine substrate: Biotin lamin-B protein Toxoplasma gondii diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine substrate: Ras-CVIM and GST-PEP Bos taurus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine enzyme prefers Gln and Met at the X position but not Ser, Thr or Cys, which are good substrates for mammalian enzyme Trypanosoma brucei brucei diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine enzyme prefers Gln and Met at the X position but not Ser, Thr or Cys, which are good substrates for mammalian enzyme Trypanosoma cruzi diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine enzyme prefers Gln and Met at the X position but not Ser, Thr or Cys, which are good substrates for mammalian enzyme Leishmania major diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine enzyme prefers linear residues in the X position of the CaaX box over branched residues, enzyme prefers Gln, Met and Ser at the X position Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine substrates are cellular proteins such as Ras at a cysteine residue near their carboxy-terminus Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine prenylation, farnesylation, substrates are Ras, nuclear lamins, transducin gamma subunit, protein substrate motif: Cys-aliphatic-aliphatic-X, X: M, S, Q, A, F Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine prenylation, farnesylation, substrates are Ras, nuclear lamins, transducin gamma subunit, protein substrate motif: Cys-aliphatic-aliphatic-X, X: M, S, Q, A, F Rattus norvegicus diphosphate + S-farnesyl protein - ir 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine prenylation, farnesylation, substrates are Ras, nuclear lamins, transducin gamma subunit, protein substrate motif: Cys-aliphatic-aliphatic-X, X: M, S, Q, A, F Saccharomyces cerevisiae diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine prenylation, farnesylation, substrates are Ras, nuclear lamins, transducin gamma subunit, protein substrate motif: Cys-aliphatic-aliphatic-X, X: M, S, Q, A, F Pisum sativum diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine preferred CaaX-substrate: CAIM Rattus norvegicus diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine preferred CaaX-substrate: CAIM Saccharomyces cerevisiae diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine Ftase has an autonomous recognition sequence, referred to as the CAAX box, where C is a cysteine, A is usually an aliphatic amino acid, and X can be a variety of amino acids Homo sapiens diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Leishmania amazonensis LV78 diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine Ha-Ras-CVLS, which is a good substrate for mammalian enzyme, not farnesylated by the parasite enzyme, only the mammalian enzyme substrate RAS1-CVIM farnesylated by parasite enzyme Trypanosoma brucei brucei EATRO 140 diphosphate + S-farnesyl protein - ? 354401 2.5.1.58 farnesyl diphosphate + protein-cysteine - Homo sapiens S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine - Rattus norvegicus S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine - Saccharomyces cerevisiae S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine process required for the transforming activity of oncogenic variants of Ras, making enzyme a prime target for anticancer therapeutics Homo sapiens S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine process required for the transforming activity of oncogenic variants of Ras, making enzyme a prime target for anticancer therapeutics Rattus norvegicus S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine process required for the transforming activity of oncogenic variants of Ras, making enzyme a prime target for anticancer therapeutics Saccharomyces cerevisiae S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine process necessary for the subcellular localisation of substrate to the plasma membrane Homo sapiens S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine process necessary for the subcellular localisation of substrate to the plasma membrane Rattus norvegicus S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine process necessary for the subcellular localisation of substrate to the plasma membrane Saccharomyces cerevisiae S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine enzyme responsible for catalysing isoprene lipid modifications Rattus norvegicus S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine enzyme responsible for catalysing isoprene lipid modifications Toxoplasma gondii S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine A series of steps modifies the C-terminus of Ras. Enzyme catalyses the first of these steps by transferring the farnesyl group from farnesyl diphosphates to the cysteine side chain in the CAAX sequence motif at the C-terminus of Ras Rattus norvegicus S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine potential role for plant enzyme in cell cycle regulation Pisum sativum S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine potential role for plant enzyme in cell cycle regulation Nicotiana tabacum S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine a possible role for the enzyme during fruit development Solanum lycopersicum S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine potential role for cell cycle Plasmodium falciparum S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine catalyzes the post-translational modification of many important cellular proteins Rattus norvegicus S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine protein farnesylation is essential for early embryonic proliferation but dispensable for postnatal development and adult homeostasis. Ablation of FTase during tumor progression results in significant tumor reduction Mus musculus S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine the enzyme catalyzes posttranslational modification of proteins, the farnesyl moieties attached to the substrates are direcly involved in protein-protein interactions as well as in protein-membrane interactions Homo sapiens S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + protein-cysteine substrate motif: carboxy-terminal -Ca1a2X box Homo sapiens S-farnesyl protein + diphosphate - ? 370439 2.5.1.58 farnesyl diphosphate + Ras oncoprotein p21 - Homo sapiens diphosphate + Ras-S-farnesyl oncoprotein p21 - ? 397159 2.5.1.58 farnesyl diphosphate + Ras protein - Homo sapiens diphosphate + S-farnesyl Ras protein - ? 397160 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Ile-Met - Homo sapiens diphosphate + Ras-S-farnesyl-Cys-Val-Ile-Met - ? 354402 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Ile-Met - Rattus norvegicus diphosphate + Ras-S-farnesyl-Cys-Val-Ile-Met - ? 354402 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Ile-Met - Bos taurus diphosphate + Ras-S-farnesyl-Cys-Val-Ile-Met - ? 354402 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Ile-Met - Trypanosoma brucei brucei diphosphate + Ras-S-farnesyl-Cys-Val-Ile-Met - ? 354402 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Ile-Met best substrate Rattus norvegicus diphosphate + Ras-S-farnesyl-Cys-Val-Ile-Met - ? 354402 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Ile-Met best substrate Solanum lycopersicum diphosphate + Ras-S-farnesyl-Cys-Val-Ile-Met - ? 354402 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Ile-Met - Trypanosoma brucei brucei EATRO 140 diphosphate + Ras-S-farnesyl-Cys-Val-Ile-Met - ? 354402 2.5.1.58 farnesyl diphosphate + Ras-Cys-Val-Leu-Met - Homo sapiens diphosphate + Ras-S-farnesyl-Cys-Val-Leu-Met - ? 397161 2.5.1.58 farnesyl diphosphate + Thr-Lys-Cys-Val-Ile-Leu - Escherichia coli Thr-Lys-S-farnesyl-Cys-Val-Ile-Leu + diphosphate - ? 376782 2.5.1.58 farnesyl diphosphate + Thr-Lys-Cys-Val-Ile-Met - Escherichia coli Thr-Lys-S-farnesyl-Cys-Val-Ile-Met + diphosphate - ? 376783 2.5.1.58 farnesyl diphosphate + Thr-Lys-Cys-Val-Ile-Phe - Escherichia coli Thr-Lys-S-farnesyl-Cys-Val-Ile-Phe + diphosphate - ? 376784 2.5.1.58 farnesyl diphosphate + Thr-Lys-Cys-Val-Ile-Ser - Escherichia coli Thr-Lys-S-farnesyl-Cys-Val-Ile-Ser + diphosphate - ? 376785 2.5.1.58 farnesyl diphosphate + Thr-Lys-Cys-Val-Leu-Ala - Escherichia coli Thr-Lys-S-farnesyl-Cys-Val-Leu-Ala + diphosphate - ? 376786 2.5.1.58 farnesyl diphosphate + Thr-Lys-Val-Ile-Phe - Escherichia coli ? - ? 453936 2.5.1.58 farnesyl diphosphate + [GST]-Cys-Ile-Ile-Ser - Saccharomyces cerevisiae diphosphate + S-farnesyl-[GST]-Cys-Ile-Ile-Ser - ? 354412 2.5.1.58 farnesyl diphosphate + [protein]-L-cysteine assay at pH 7.8, 25°C Rattus norvegicus [protein]-S-((2E,6E)-farnesyl)-L-cysteine + diphosphate - ? 409397 2.5.1.58 farnesyl monophosphate + Gly-Cys-Val-Leu-Ser - Rattus norvegicus phosphate + Gly-S-farnesyl-Cys-Val-Leu-Ser - ? 354411 2.5.1.58 farnesyl triphosphate + [Ras]-Cys-Val-Ile-Met - Homo sapiens triphosphate + [Ras]-S-farnesyl-Cys-Val-Ile-Met - ? 397164 2.5.1.58 geranyl alkyne diphosphate + N-dansyl-GCVIA - Saccharomyces cerevisiae N-dansyl-G-(alkyne geranyl)CVIA + diphosphate - ir 388750 2.5.1.58 geranyl diphosphate + dansyl-GCVLS - Rattus norvegicus dansyl-G-(S-geranyl)CVLS + diphosphate - ? 409486 2.5.1.58 geranylgeranyl diphosphate + N-dansyl-Gly-Cys-Val-Leu-Ser - Rattus norvegicus diphosphate + N-dansyl-Gly-S-geranylgeranyl-Cys-Val-Leu-Ser - ? 354405 2.5.1.58 geranylgeranyl diphosphate + protein-cysteine - Rattus norvegicus diphosphate + S-geranylgeranylcysteinyl protein - ? 354403 2.5.1.58 HOM-GPP + N-dansyl-GCVLS - Homo sapiens ? - ? 397435 2.5.1.58 additional information although farnesyl diphosphate and geranylgeranyl diphosphate bind competitively, the geranyl geranyl diphosphate is not transferred efficiently to the protein substrate by enzyme Rattus norvegicus ? - ? 89 2.5.1.58 additional information not: geranylgeranyl diphosphate Rattus norvegicus ? - ? 89 2.5.1.58 additional information biotin-GPP is not transferred to the peptide substrate to any measurable extent Homo sapiens ? - ? 89 2.5.1.58 additional information steady-state kinetics for modification of peptide substrates shows that the multiple-turnover activity depends on the analogue structure. Analogues in which the first isoprene is replaced with a benzyl group and an analogue in which each isoprene is replaced with an aryl group are good substrates. The single-turnover rate constant for alkylation depends on the Ca1a2X peptide sequence. The isoprenoid transition-state conformation is preferred over the inactive E-FPP-Ca1a2X ternary complex conformation and the farnesyl binding site in the exit groove may be significantly more selective for the farnesyl diphosphate substrate than the active site binding pocket Rattus norvegicus ? - ? 89 2.5.1.58 additional information ligand interaction analysis with FTase alpha subunit, mass spectrometry, overview. The enzyme alpha-subunit interacts with Vps4A protein in vitro and in vivo Rattus norvegicus ? - ? 89 2.5.1.58 additional information ligand interaction analysis with FTase alpha subunit, mass spectrometry, overview. The enzyme alpha-subunit interacts with Vps4A protein in vitro and in vivo Saccharomyces cerevisiae ? - ? 89 2.5.1.58 additional information analogues of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase, reactivity of four alkyne-containing analogs of farnesyl diphosphate with purified protein farnesyltransferase and a small library of dansylated peptides using an in vitro continuous spectrofluorimetric assay, overview. Activity with CGGDD, CVLL, and CSVL peptides is low with farnesyl diphosphate as well as with its analogues Rattus norvegicus ? - ? 89 2.5.1.58 additional information enzyme-substrate interaction study using synthetic peptides as substrates, modelling of the enzyme interaction with substrate protein tyrosine phosphatase, protein-protein docking and molecular dynamics simulation, overview Plasmodium falciparum ? - ? 89 2.5.1.58 additional information FTase-I can transfer isoprenoids to intracellular proteins that contain CAAX motifs. The isoprenoid groups can be selectively recognized by GGTase-I. The 15-carbon isoprenoid geranylgeranyl from its donor farnesyldiphosphate (FPP) is specific to FTase-I. Residues Lysalpha164, Hisbeta248, Argbeta291 and Tyrbeta300 in FTase can form hydrogen bonds with farnesyl diphosphate. When FTase is inhibited by a FTI, N-Ras and K-Ras can be alternatively prenylated by GGTase-I, EC 2.5.1.59, but H-Ras cannot Rattus norvegicus ? - ? 89 2.5.1.58 additional information FTase-I can transfer isoprenoids to intracellular proteins that contain CAAX motifs. The isoprenoid groups can be selectively recognized by GGTase-I. The 15-carbon isoprenoid geranylgeranyl from its donor farnesyldiphosphate (FPP) is specific to FTase-I. Residues Lysalpha164, Hisbeta248, Argbeta291 and Tyrbeta300 in FTase can form hydrogen bonds with farnesyl diphosphate. When FTase is inhibited by a FTI, N-Ras and K-Ras can be alternatively prenylated by GGTase-I, EC 2.5.1.59, but H-Ras cannot Homo sapiens ? - ? 89 2.5.1.58 additional information protein farnesytransferase catalyzes the farnesylation of proteins with a C-terminal tetrapeptide sequence denoted as a Ca1a2X box, determination of substrate recognition sequences, and substrate specificity, screening of the CVa2X library with alkyne-functionalized isoprenoid substrates, detailed overview Candida albicans ? - ? 89 2.5.1.58 additional information protein farnesytransferase catalyzes the farnesylation of proteins with a C-terminal tetrapeptide sequence denoted as a Ca1a2X box, determination of substrate recognition sequences, and substrate specificity, screening of the CVa2X library with alkyne-functionalized isoprenoid substrates, detailed overview Rattus norvegicus ? - ? 89 2.5.1.58 additional information protein farnesytransferase catalyzes the farnesylation of proteins with a C-terminal tetrapeptide sequence denoted as a Ca1a2X box, determination of substrate recognition sequences, and substrate specificity, screening of the CVa2X library with alkyne-functionalized isoprenoid substrates, detailed overview Saccharomyces cerevisiae ? - ? 89 2.5.1.58 additional information enzyme prefers farnesyl diphosphate over geranylgeranyl diphosphate, but catalyzes the reactions of both substrates, i.e. reactions of EC 2.5.1.58 and EC 2.5.1.59, respectively Rattus norvegicus ? - - 89 2.5.1.58 TKCVIA + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIA + diphosphate - ? 389885 2.5.1.58 TKCVIC + farnesyl diphosphate - Rattus norvegicus diphosphate + ? - ? 389886 2.5.1.58 TKCVID + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVID + diphosphate - ? 389887 2.5.1.58 TKCVIF + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIF + diphosphate - ? 389888 2.5.1.58 TKCVII + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVII + diphosphate - ? 389889 2.5.1.58 TKCVIL + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIL + diphosphate - ? 389890 2.5.1.58 TKCVIM + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIM + diphosphate - ? 389891 2.5.1.58 TKCVIN + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIN + diphosphate - ? 389892 2.5.1.58 TKCVIQ + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIQ + diphosphate - ? 389893 2.5.1.58 TKCVIR + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIR + diphosphate - ? 389894 2.5.1.58 TKCVIS + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIS + diphosphate - ? 389895 2.5.1.58 TKCVIT + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIT + diphosphate - ? 389896 2.5.1.58 TKCVIV + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIV + diphosphate - ? 389897 2.5.1.58 TKCVIY + farnesyl diphosphate - Rattus norvegicus TK-(S-farnesyl)CVIY + diphosphate - ? 389898 2.5.1.58 YRASNRSCAIM + farnesyl diphosphate - Plasmodium falciparum YRASNRS-(S-farnesyl)CAIM + diphosphate - ? 390094 2.5.1.58 [(4E,8E,10E)-4,8-dimethyl-10-(oxodiphosphanylidene)deca-4,8-dien-1-yl]oxyacetonitrile + protein-cysteine - Saccharomyces cerevisiae ? - ? 398592