2.5.1.39	4-hydroxybenzoate + solanesyl-diphosphate	i.e.all-trans nonaprenyl diphosphate	Rattus norvegicus	4-hydroxy-3-nonaprenylbenzoate + diphosphate	-	?	408095	
2.5.1.39	a polyprenyl diphosphate + 4-hydroxybenzoate	-	Mus musculus	diphosphate + a 4-hydroxy-3-polyprenylbenzoate	-	?	421832	
2.5.1.39	a polyprenyl diphosphate + 4-hydroxybenzoate	Coq2 is quite unspecific with regard to its substrates	Mus musculus	diphosphate + a 4-hydroxy-3-polyprenylbenzoate	-	?	421832	
2.5.1.39	decaprenyl diphosphate + 4-hydroxybenzoate	-	Saccharomyces cerevisiae	diphosphate + decaprenyl-4-hydroxybenzoate	-	?	375105	
2.5.1.39	decaprenyl diphosphate + 4-hydroxybenzoate	-	Homo sapiens	diphosphate + decaprenyl-4-hydroxybenzoate	-	?	375105	
2.5.1.39	decaprenyl diphosphate + 4-hydroxybenzoate	preferred substrate	Homo sapiens	diphosphate + decaprenyl-4-hydroxybenzoate	-	?	375105	
2.5.1.39	farnesyl diphosphate + 4-hydroxybenzoate	-	Escherichia coli	farnesyl-4-hydroxybenzoate + diphosphate	-	?	354021	
2.5.1.39	farnesyl diphosphate + 4-hydroxybenzoate	at 1% of the activity with nonaprenyl diphosphate	Pseudomonas putida	farnesyl-4-hydroxybenzoate + diphosphate	-	?	354021	
2.5.1.39	farnesyl diphosphate + 4-hydroxybenzoate	-	Oryza sativa	3-farnesyl-4-hydroxybenzoate + diphosphate	-	?	388675	
2.5.1.39	geranyl diphosphate + 4-hydroxybenzoate	-	Escherichia coli	3-geranyl-4-hydroxybenzoate + diphosphate	-	?	354023	
2.5.1.39	geranyl diphosphate + 4-hydroxybenzoate	-	Mus musculus	diphosphate + 3-geranyl-4-hydroxybenzoate	-	?	376841	
2.5.1.39	geranyl diphosphate + 4-hydroxybenzoate	-	Oryza sativa	diphosphate + 3-geranyl-4-hydroxybenzoate	-	?	376841	
2.5.1.39	geranyl diphosphate + 4-hydroxybenzoate	-	Arabidopsis thaliana	diphosphate + 3-geranyl-4-hydroxybenzoate	-	?	376841	
2.5.1.39	geranylgeranyl diphosphate + 4-hydroxybenzoate	-	Escherichia coli	geranylgeranyl-4-hydroxybenzoate + diphosphate	-	?	354024	
2.5.1.39	geranylgeranyl diphosphate + 4-hydroxybenzoate	various derivatives of 4-hydroxybenzoate can be used as substrate	Escherichia coli	geranylgeranyl-4-hydroxybenzoate + diphosphate	-	?	354024	
2.5.1.39	geranylgeranyl diphosphate + 4-hydroxybenzoate	-	Oryza sativa	3-geranylgeranyl-4-hydroxybenzoate + diphosphate	-	?	388753	
2.5.1.39	hexaprenyl diphosphate + 4-hydroxybenzoate	at 68% of the activity with nonaprenyl diphosphate	Pseudomonas putida	hexaprenyl-4-hydroxybenzoate + diphosphate	-	?	354018	
2.5.1.39	additional information	no substrate: geranyl monophosphate	Escherichia coli	?	-	?	89	
2.5.1.39	additional information	detergents can affect the specificity of the mitochondrial system synthesizing polyprenyl diphosphates	Cavia porcellus	?	-	?	89	
2.5.1.39	additional information	detergents can affect the specificity of the mitochondrial system synthesizing polyprenyl diphosphates	Rattus norvegicus	?	-	?	89	
2.5.1.39	additional information	no substrate: nonaprenyl monophosphate	Cavia porcellus	?	-	?	89	
2.5.1.39	additional information	no substrate: nonaprenyl monophosphate	Rattus norvegicus	?	-	?	89	
2.5.1.39	additional information	key enzyme in biosynthesis of ubiquinone, the enzyme is required for embryo development	Arabidopsis thaliana	?	-	?	89	
2.5.1.39	additional information	the enzyme is required for biosynthesis of CoQ2, i.e. ubiquinone	Saccharomyces cerevisiae	?	-	?	89	
2.5.1.39	additional information	the enzyme is required for biosynthesis of CoQ2, i.e. ubiquinone	Homo sapiens	?	-	?	89	
2.5.1.39	additional information	enzyme shows broad substrate specificity in terms of prenyl substrates	Arabidopsis thaliana	?	-	?	89	
2.5.1.39	additional information	the enzyme catalyzes the prenylation of 4-hydroxybenzoate with an all-trans polyprenyl group	Saccharomyces cerevisiae	?	-	?	89	
2.5.1.39	additional information	the enzyme catalyzes the prenylation of 4-hydroxybenzoate with an all-trans polyprenyl group	Homo sapiens	?	-	?	89	
2.5.1.39	additional information	in the presence of Mg2+ the enzyme is also able to hydrolyze geranyl diphosphate without forming geranylgeranyl-4-hydroxybenzoate	Escherichia coli	?	-	?	89	
2.5.1.39	additional information	one active site selected to be the most likely one for the docking of oligoprenyl diphosphate and 4-hydroxybenzoic acid is located near the N-terminus of the enzyme. An additional highly conserved region in the amino acid sequence of the ubiA enzyme is detected, which can be considered a putative active site	Escherichia coli	?	-	?	89	
2.5.1.39	additional information	decaprenyl diphosphate and 4-hydroxybenzoate are condensed in a reaction catalyzed by 4-hydroxybenzoate:polyprenyl transferase, i.e. COQ2	Homo sapiens	?	-	?	89	
2.5.1.39	octaprenyl diphosphate + 4-hydroxybenzoate	-	Escherichia coli	4-hydroxy-3-octaprenylbenzoate + diphosphate	-	?	409991	
2.5.1.39	pentaprenyl diphosphate + 4-hydroxybenzoate	86% of the activity with nonaprenyl diphosphate	Pseudomonas putida	pentaprenyl-4-hydroxybenzoate + diphosphate	-	?	354019	
2.5.1.39	phytyl diphosphate + 4-hydroxybenzoate	at 1% of the activity with nonaprenyl diphosphate	Pseudomonas putida	phytyl-4-hydroxybenzoate + diphosphate	-	?	354022	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Escherichia coli	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Homo sapiens	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Homo sapiens	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	ir	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Schizosaccharomyces pombe	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	ir	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	i.e. nonaprenyl diphosphate	Rattus norvegicus	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	i.e. nonaprenyl diphosphate	Pseudomonas putida	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	i.e. nonaprenyl diphosphate	Cavia porcellus	diphosphate + 3-solanesyl-4-hydroxybenzoate	3-nonaprenyl-4-hydroxybenzoate	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	i.e. nonaprenyl diphosphate	Rattus norvegicus	diphosphate + 3-solanesyl-4-hydroxybenzoate	3-nonaprenyl-4-hydroxybenzoate	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	i.e. nonaprenyl diphosphate	Rattus norvegicus	diphosphate + 3-solanesyl-4-hydroxybenzoate	small amounts of decaprenyl-4-hydroxybenzoate and octaprenylhydroxybenzoate can be found, depending on source of enzyme and substrate used to provide polyprenyl side chains	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	key enzyme in ubiquinone synthesis, it catalyzes the step which brings together the precursor of the benzoquinone ring and the polyisoprenoid side chain, in rat liver the major product is 3-nonaprenyl-4-hydroxybenzoate, in human and guinea pig it is 3-decaprenyl-4-hydroxybenzoate	Rattus norvegicus	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	involved in the biosynthesis of ubiquinone	Escherichia coli	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	involved in the biosynthesis of ubiquinone	Rattus norvegicus	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	involved in the biosynthesis of ubiquinone	Schizosaccharomyces pombe	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	involved in biosynthesis of ubiquinone and vitamin E	Escherichia coli	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	i.e. nonaprenyl diphosphate	Pseudomonas putida IAM 1219	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	?	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Schizosaccharomyces pombe SPQ-01	diphosphate + 3-solanesyl-4-hydroxybenzoate	-	ir	354017	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Saccharomyces cerevisiae	diphosphate + nonaprenyl-4-hydroxybenzoate	-	?	375302	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Homo sapiens	diphosphate + nonaprenyl-4-hydroxybenzoate	-	?	375302	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Arabidopsis thaliana	diphosphate + nonaprenyl-4-hydroxybenzoate	-	?	375302	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	-	Rattus norvegicus	diphosphate + 4-hydroxy-3-nonaprenylbenzoate	-	?	410309	
2.5.1.39	solanesyl diphosphate + 4-hydroxybenzoate	i.e. all-trans nonaprenyl diphosphate	Spinacia oleracea	diphosphate + 4-hydroxy-3-nonaprenylbenzoate	-	?	410309	
2.5.1.39	tetraprenyl diphosphate + 4-hydroxybenzoate	6% of the activity with nonaprenyl diphosphate	Pseudomonas putida	tetraprenyl-4-hydroxybenzoate + diphosphate	-	?	354020