2.4.2.64	dihydroqueuine + tRNAguanine	-	Xenopus laevis	guanine + tRNAdihydroqueuine	-	?	359609	
2.4.2.64	guanine34 in tRNA + 7-(aminomethyl)-7-deazaguanine	the affinity of the rat liver tRNA-guanine transglycosylase for queuine is much greater than that for 7-(aminomethyl)-7-deazaguanine and guanine	Rattus norvegicus	7-(aminomethyl)-7-deazaguanine34 in tRNA + guanine	-	?	458032	
2.4.2.64	guanine34 in tRNA + 7-aminomethyl-7-carbaguanine	very low activity with wild-type enzyme. The mutant enzyme V161C exhibits a significant improvement in preQ1 (7-aminomethyl-7-deazaguanine) recognition	Homo sapiens	7-aminomethyl-7-carbaguanine34 in tRNA + guanine	-	?	359605	
2.4.2.64	guanine34 in tRNA + queuine	-	Drosophila melanogaster	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Escherichia coli	queuine34 in tRNA + guanine	-	r	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Rattus norvegicus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Triticum aestivum	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Oryctolagus cuniculus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Zymomonas mobilis	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Homo sapiens	queuine34 in tRNA + guanine	-	r	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Homo sapiens	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	-	Mus musculus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	nucleosides in position 36, 37 and 38 influence the efficiency of conversion of G-34 to queuosine-34	Xenopus laevis	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	catalyses a base-exchange reaction that leads to anticodon modifications of certain tRNAs	Zymomonas mobilis	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	the enzyme is responsible for the formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr	Mus musculus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr	Mus musculus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	human tyrosyl tRNA Tyr. The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNA via a sequential bi-bi mechanism	Homo sapiens	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	in the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine	Oryctolagus cuniculus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	the affinity of the rat liver tRNA-guanine transglycosylase for queuine is much greater than that for 7-(aminomethyl)-7-deazaguanine and guanine	Rattus norvegicus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	the enzyme replaces a guanine in the anticodon of tRNAs for Asn, Asp, His, and Tyr. In the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine	Drosophila melanogaster	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA + queuine	the enzyme replaces a guanine in the anticodon of tRNAs for Asn, Asp, His, and Tyr. In the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine	Oryctolagus cuniculus	queuine34 in tRNA + guanine	-	?	359608	
2.4.2.64	guanine34 in tRNA(Tyr) + queuine	-	Mus musculus	queuine34 in tRNA(Tyr) + guanine	-	?	458033	
2.4.2.64	additional information	-	Escherichia coli	?	-	?	89	
2.4.2.64	additional information	key enzyme involved in the incorporation of the modified base queuine into tRNA	Escherichia coli	?	-	?	89	
2.4.2.64	additional information	higher expression of the subunit TGT60KD in cancer cells than in normal cells. The expression levels of the TGT60KD subunit regulate enzyme activity and the level of queuosine. TGT60KD plays significant roles in carcinogenesis	Homo sapiens	?	-	-	89	
2.4.2.64	additional information	the enzyme is required for virulence	Shigella flexneri	?	-	?	89	
2.4.2.64	additional information	the 60000 Da subunit of the enzyme plays a role in colon carcinogenesis	Homo sapiens	?	-	-	89	
2.4.2.64	tRNAqueuine + guanine	-	Escherichia coli	tRNAguanine + queuine	-	?	393731	
2.4.2.64	tRNAqueuine + hypoxanthine	-	Escherichia coli	tRNAhypoxanthine + queuine	-	?	393732	
2.4.2.64	tRNAqueuine + xanthine	-	Escherichia coli	tRNAxanthine + queuine	-	?	393733	
2.4.2.64	[tRNATyr]queuine + guanine	human TGT is composed of a catalytic subunit, QTRT1, and QTRTD1, not USP14. QTRTD1 is the salvage enzyme that generates free queuine from QMP	Homo sapiens	[tRNATyr]-guanine + queuine	-	?	410666