2.4.2.44 5'-methylthioinosine + phosphate - Pseudomonas aeruginosa hypoxanthine + 5-methylthio-alpha-D-ribose 1-phosphate - 354420 2.4.2.44 adenosine + phosphate weak substrate Pseudomonas aeruginosa adenine + alpha-D-ribose 1-phosphate - 323170 2.4.2.44 adenosine + phosphate - Pseudomonas aeruginosa adenine + D-ribose 1-phosphate - 354432 2.4.2.44 inosine + phosphate the catalytic efficiency (kcat/Km) for S-methyl-5'-thioinosine is 290 times larger than for inosine Pseudomonas aeruginosa hypoxanthine + alpha-D-ribose 1-phosphate - 323149 2.4.2.44 inosine + phosphate - Pseudomonas aeruginosa hypoxanthine + D-ribose 1-phosphate - 354433 2.4.2.44 additional information S-methyl-5'-thioadenosine is not a substrate Pseudomonas aeruginosa ? - 89 2.4.2.44 S-methyl-5'-thioinosine + phosphate the enzyme is involved in catabolism of 5'-methylthioadenosine in Pseudomonas aeruginosa. S-Methyl-5'-thioadenosine is converted to S-methyl-5'-thioinosine and hypoxanthine but not to adenine Pseudomonas aeruginosa hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate - 411012 2.4.2.44 S-methyl-5'-thioinosine + phosphate the methylthio group of S-methyl-5'-thioinosine is important for both substrate binding and catalysis Pseudomonas aeruginosa hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate - 411012