2.1.1.304 additional information activity with L-DOPA is 1% of the activity with L-tyrosine 89 2.1.1.304 additional information activity with L-DOPA is 2% of the activity with L-tyrosine 89 2.1.1.304 S-adenosyl-L-methionine + D-tyrosine 24% of the activity as compared to L-tyrosine 456462 2.1.1.304 S-adenosyl-L-methionine + D-tyrosine 64% of the activity as compared to L-tyrosine 456462 2.1.1.304 S-adenosyl-L-methionine + L-tyrosine - 425019 2.1.1.304 S-adenosyl-L-methionine + L-tyrosine the enzyme is involved in biosynthesis of saframycin A, a potent antitumor antibiotic that belongs to the tetrahydroisoquinoline family 425019 2.1.1.304 S-adenosyl-L-methionine + L-tyrosine the enzyme is highly selective with regard to their natural substrate. The enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Saframycin (antibiotic) 425019 2.1.1.304 S-adenosyl-L-methionine + L-tyrosine the enzyme is involved in the biosynthesis of 3'-methyltyrosine, which is the precursor of the tetrahydroisoquinoline moiety in Safracin (antibiotic) 425019 2.1.1.304 S-adenosyl-L-methionine + L-tyrosine the enzyme is highly selective with regard to their natural substrate 425019