2.1.1.208 S-adenosyl-L-methionine + uridine2479 in 23S rRNA - 411009 2.1.1.208 S-adenosyl-L-methionine + uridine2479 in 23S rRNA AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of uridine2479 of the 23S ribosomal RNA in Gram-positive bacteria and thus mediates resistance to the oligosaccharide antibiotic avilamycin 411009 2.1.1.208 S-adenosyl-L-methionine + uridine2479 in 23S rRNA AviRb modifies the 2'-O-ribose position of nucleotide uridine2479 within helix 89 411009 2.1.1.208 S-adenosyl-L-methionine + uridine2479 in 23S rRNA AviRb modifies the 2'-O-ribose position of nucleotide uridine2479 within helix 89. The exact position of the modification is conformed by MALDI mass spectrometry, a single methyl group is added. No methylation activity with 16S rRNA 411009