1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	-	Methanosarcina barkeri	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	-	Methanosarcina mazei	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	no activity with ferredoxin	Methanosarcina barkeri	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	enzyme is part of a membrane-bound electron transport system in methanogenesis	Methanosarcina barkeri	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	enzyme is part of a membrane-bound electron transport system in methanogenesis	Methanosarcina mazei	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	coenzyme F420-dependent reduction of 2-hydroxyphenazine as catalyzed by the membrane-bound enzyme is coupled to proton translocation across the cytoplasmic membrane, exhibiting a stoichiometry of 0.9 H+ translocated per two electrons transferred. The electrochemical proton gradient thereby generated drives ATP synthesis from ADP and diphosphate	Methanosarcina mazei	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	cofactor F420(H2)-dependent reduction of 2-hydroxyphenazine as catalyzed by the membrane-bound enzyme is coupled to proton translocation across the cytoplasmic membrane, exhibiting a stoichiometry of 0.9 H+ translocated per two electrons transferred	Methanosarcina mazei	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	coenzyme F420-dependent reduction of 2-hydroxyphenazine as catalyzed by the membrane-bound enzyme is coupled to proton translocation across the cytoplasmic membrane, exhibiting a stoichiometry of 0.9 H+ translocated per two electrons transferred. The electrochemical proton gradient thereby generated drives ATP synthesis from ADP and diphosphate	Methanosarcina mazei DSM 3647	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-(2,3-dihydropentaprenyloxy)phenazine	cofactor F420(H2)-dependent reduction of 2-hydroxyphenazine as catalyzed by the membrane-bound enzyme is coupled to proton translocation across the cytoplasmic membrane, exhibiting a stoichiometry of 0.9 H+ translocated per two electrons transferred	Methanosarcina mazei DSM 3647	2-dihydropentaprenyloxyphenazine	-	?	289303	
1.12.98.3	H2 + 2-hydroxyphenazine	-	Methanosarcina mazei	dihydro-2-hydroxyphenazine	-	?	289304	
1.12.98.3	H2 + oxidized methyl viologen	-	Methanosarcina sp.	reduced methyl viologen	-	?	289302	
1.12.98.3	additional information	growth on H2-CO2	Methanosarcina barkeri	?	-	?	89	
1.12.98.3	additional information	no growth on H2-CO2, inability to metabolize hydrogen, the lack of hydrogenase activity in Methanosarcina acetivorans extracts is not due to obvious mutations in either the coding regions or the promoters, hydrogenases are inactivated at the level of transcription and/or translation, Methanosarcina acetivorans possesses the machinery to express hydrogenases, although it does not express its own hydrogenases. This is consistent with specific inactivation of the Methanosarcina acetivorans hydrogenase promoters and highlight the importance of testing hypotheses generated by using genomic data	Methanosarcina acetivorans	?	-	?	89