1.1.1.22 3-OH-benzopyrene + NAD+ - Rattus norvegicus ? - ? 187831 1.1.1.22 5-azido-UDP-glucose + NAD+ - Homo sapiens 5-azido-UDP-glucuronate + NADH + H+ - ? 383953 1.1.1.22 5-fluorouracil + NAD+ - Bos taurus ? - ? 187829 1.1.1.22 6-azauracil + NAD+ - Bos taurus ? - ? 187830 1.1.1.22 CDP-glucose + NAD+ + H2O 17% of the reaction rate with UDP-glucose Lilium longiflorum CDP-glucuronate + NADH - ? 187826 1.1.1.22 CDP-glucose + NAD+ + H2O reaction rate is 5.5% of that with UDP-glucose Escherichia coli CDP-glucuronate + NADH - ? 187826 1.1.1.22 CTP-glucose + NAD+ 8% of activity with UDP-glucose Saccharum spp. CTP-glucuronate + NADH - ir 372783 1.1.1.22 dTDP-glucose + NAD+ + H2O reaction rate is 16.7% of that with UDPglucose Escherichia coli dTDP-glucuronate + NADH - ? 187827 1.1.1.22 additional information no reaction with ethylnicotinate adenine dinucleotide Papiliotrema laurentii ? - ? 89 1.1.1.22 additional information nicotinamide hypoxanthine dinucleotide Rattus norvegicus ? - ? 89 1.1.1.22 additional information cosubstrates which can replace NAD+: 3-acetylpyridine adenine dinucleotide Escherichia coli ? - ? 89 1.1.1.22 additional information cosubstrates which can replace NAD+: 3-acetylpyridine adenine dinucleotide Bos taurus ? - ? 89 1.1.1.22 additional information cosubstrates which can replace NAD+: 3-acetylpyridine adenine dinucleotide Papiliotrema laurentii ? - ? 89 1.1.1.22 additional information no reaction with alpha-NAD+ Rattus norvegicus ? - ? 89 1.1.1.22 additional information no reaction with alpha-NAD+ Papiliotrema laurentii ? - ? 89 1.1.1.22 additional information 3-pyridinealdehyde adenine dinucleotide Escherichia coli ? - ? 89 1.1.1.22 additional information no reaction with 3-formylpyridine adenine dinucleotide Papiliotrema laurentii ? - ? 89 1.1.1.22 additional information no reaction with NADP+ Bos taurus ? - ? 89 1.1.1.22 additional information no reaction with NADP+ Lilium longiflorum ? - ? 89 1.1.1.22 additional information thionicotinamide adenine dinucleotide Escherichia coli ? - ? 89 1.1.1.22 additional information thionicotinamide adenine dinucleotide Papiliotrema laurentii ? - ? 89 1.1.1.22 additional information no activity with GTP-glucose Escherichia coli ? - ? 89 1.1.1.22 additional information no reaction with: 3-pyridinealdehyde deamino adenosine dinucleotide Escherichia coli ? - ? 89 1.1.1.22 additional information no activity with glucose Bos taurus ? - ? 89 1.1.1.22 additional information deamino adenine dinucleotide Escherichia coli ? - ? 89 1.1.1.22 additional information deamino adenine dinucleotide Bos taurus ? - ? 89 1.1.1.22 additional information no activity with uridine diphosphoacetylgalactosamine Bos taurus ? - ? 89 1.1.1.22 additional information no activity with ethyl alcohol Bos taurus ? - ? 89 1.1.1.22 additional information no reaction with deamino-NAD+ Papiliotrema laurentii ? - ? 89 1.1.1.22 additional information no activity with alpha-D-glucose-1-phosphate Bos taurus ? - ? 89 1.1.1.22 additional information no activity with guanosine diphosphomannose Bos taurus ? - ? 89 1.1.1.22 additional information no activity with uridine diphosphoacetylglucosamine Bos taurus ? - ? 89 1.1.1.22 additional information no activity with ADP-glucose Escherichia coli ? - ? 89 1.1.1.22 additional information no reaction with 3-propionylpyridine adenine dinucleotide Papiliotrema laurentii ? - ? 89 1.1.1.22 additional information no substrate: ADP-glucose Saccharum spp. ? - ? 89 1.1.1.22 additional information no substrate: UDP-galactose, UDP-N-galactosamin, ADP-glucose, GDP-glucose, GDP-mannose Glycine max ? - ? 89 1.1.1.22 additional information no substrate: ADP-glucose, TDP-glucose Arabidopsis thaliana ? - ? 89 1.1.1.22 additional information expression of Ugd(BCAL2946) is 5.4- and 135fold greater than that of Ugd(BCAM0855) and Ugd(BCAM2034), respectively. Combined activity of Ugd(BCAL2946) and Ugd(BCAM0855) is essential for the survival of Burkholderia cenocepacia but only the most highly expressed ugd gene, Ugd(BCAL2946), is required for polymyxin B resistance. UDP-galactose, UDP-acetylglucosamine and GDP-mannose are not substrates Burkholderia cenocepacia J2315 ? - ? 89 1.1.1.22 additional information expression of Ugd(BCAL2946) is 5.4- and 135fold greater than that of Ugd(BCAM0855) and Ugd(BCAM2034), respectively. Combined activity of Ugd(BCAL2946) and Ugd(BCAM0855) is essential for the survival of Burkholderia cenocepacia. UDP-galactose, UDP-acetylglucosamine and GDP-mannose are not substrates Burkholderia cenocepacia J2315 ? - ? 89 1.1.1.22 additional information importance of both UDPDH and mshA gene expression for successful light organ colonization in the sepiolid squid Euprymna tasmanica Aliivibrio fischeri ? - ? 89 1.1.1.22 additional information purified Ugd(BCAM2034) shows no in vitro Ugd activity. Expression of Ugd(BCAL2946) is 5.4- and 135fold greater than that of Ugd(BCAM0855) and Ugd(BCAM2034), respectively. UDP-galactose, UDP-acetylglucosamine and GDP-mannose are not substrates Burkholderia cenocepacia J2315 ? - ? 89 1.1.1.22 additional information enzyme displays hysteresis, observed as a lag in progress curves, and is sensitive to product inhibition during the lag. The inhibition results in a systematic decrease in steady-state velocity and makes the lag appear to have a second-order dependence on enzyme concentration.The lag is in fact due to a substrate and cofactor-induced isomerization of the enzyme. The cofactor binds to the enzyme:substrate complex with negative cooperativity, suggesting that the isomerization may be related to the formation of an asymmetric enzyme complex Homo sapiens ? - ? 89 1.1.1.22 additional information no substrates: UDP-D-galactose, UTP, 5'-UMP and D-galactose Capra hircus ? - ? 89 1.1.1.22 additional information the transient capacity to dissociate and reorganize the hydrogen bond network at the interface between dimeric units is an important element of the normal catalytic cycle Homo sapiens ? - ? 89 1.1.1.22 additional information the enzyme is also not only able to bind RNA but also acts as a ribonuclease. The ribonucleolytic activity occurs independently of the presence of NAD+ and the RNA binding site does not coincide with the NAD+ binding region, kinetics of interaction between UgdG and RNA, overview. The Rossmann structural motifs found in NAD+-dependent dehydrogenases can have a dual function working as a nucleotide cofactor binding domain and as a ribonuclease Sphingomonas elodea ? - ? 89 1.1.1.22 additional information no amide products are found in the presence of added amines. The addition of either ethanolamine, ethanolamine phosphate, serinol, or serinol phosphate has no measurable effect on the catalytic properties Campylobacter jejuni subsp. jejuni ? - - 89 1.1.1.22 additional information no amide products are found in the presence of added amines. The addition of either ethanolamine, ethanolamine phosphate, serinol, or serinol phosphate has no measurable effect on the catalytic properties Campylobacter jejuni subsp. jejuni ATCC 700819 ? - - 89 1.1.1.22 additional information the enzyme is also not only able to bind RNA but also acts as a ribonuclease. The ribonucleolytic activity occurs independently of the presence of NAD+ and the RNA binding site does not coincide with the NAD+ binding region, kinetics of interaction between UgdG and RNA, overview. The Rossmann structural motifs found in NAD+-dependent dehydrogenases can have a dual function working as a nucleotide cofactor binding domain and as a ribonuclease Sphingomonas elodea ATCC 31461 ? - ? 89 1.1.1.22 TDP-glucose + NAD+ 2% of activity with UDP-glucose Saccharum spp. TDP-glucuronate + NADH - ir 374696 1.1.1.22 TDP-glucose + NAD+ + H2O reaction rate is 17% of that with UDPglucose Escherichia coli TDP-glucuronate + NADH - ? 187828 1.1.1.22 TDP-glucose + NAD+ + H2O 38.5% of the rate with UDP-glucose Pseudomonas aeruginosa TDP-glucuronate + NADH - ? 187828 1.1.1.22 UDP-2-deoxy-D-glucose + NAD+ + H2O - Bos taurus UDP-2-deoxy-D-glucuronate + NADH - ? 187825 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Escherichia coli UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Homo sapiens UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - r 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Capra hircus UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Homo sapiens UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Caenorhabditis elegans UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Sphingomonas elodea UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Pyrobaculum islandicum UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Phoma herbarum UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Burkholderia cepacia UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Streptococcus pyogenes UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Haloferax volcanii UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Larix gmelinii UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Rattus norvegicus UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Halobacterium salinarum UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Sphingomonas sanxanigenens UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Granulibacter bethesdensis UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Akkermansia muciniphila UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Campylobacter jejuni subsp. jejuni UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Sphingomonas sanxanigenens UDP-alpha-D-glucuronate + 2 NADH + 2 H+ UDP-alpha-D-glucuronate is a precursor in the synthesis of many exopolysaccharides ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Larix gmelinii UDP-alpha-D-glucuronate + 2 NADH + 2 H+ UDP-glucuronate is a key sugar nucleotide involved in biosynthesis of the plant cell wall ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Granulibacter bethesdensis UDP-alpha-D-glucuronate + 2 NADH + 2 H+ UDP-glucuronic acid is a key precursor in the biosynthesis of glycoconjugates ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O the enzyme is involved in protein N-glycosylation Haloferax volcanii UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O while the enzyme is able to process various sugar nucleotides, of those compounds tested, UDP-glucose is by far the preferred substrate of the enzyme Haloferax volcanii UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Phoma herbarum YS4108 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Streptococcus pyogenes 5448 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Campylobacter jejuni subsp. jejuni ATCC 700819 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Rattus norvegicus Wistar UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Sphingomonas sanxanigenens NX02 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Sphingomonas sanxanigenens NX02 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ UDP-alpha-D-glucuronate is a precursor in the synthesis of many exopolysaccharides ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Sphingomonas elodea ATCC 31461 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O the enzyme is involved in protein N-glycosylation Haloferax volcanii DSM 3757 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O while the enzyme is able to process various sugar nucleotides, of those compounds tested, UDP-glucose is by far the preferred substrate of the enzyme Haloferax volcanii DSM 3757 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Haloferax volcanii ATCC 29605 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O - Halobacterium salinarum ATCC 700922 UDP-alpha-D-glucuronate + 2 NADH + 2 H+ - ? 422088 1.1.1.22 UDP-alpha-D-mannose + 2 NAD+ + H2O while the enzyme is able to process various sugar nucleotides, of those compounds tested, UDP-glucose is by far the preferred substrate of the enzyme Haloferax volcanii UDP-alpha-D-mannuronate + 2 NADH + 2 H+ - ? 429001 1.1.1.22 UDP-alpha-D-mannose + 2 NAD+ + H2O while the enzyme is able to process various sugar nucleotides, of those compounds tested, UDP-glucose is by far the preferred substrate of the enzyme Haloferax volcanii DSM 3757 UDP-alpha-D-mannuronate + 2 NADH + 2 H+ - ? 429001 1.1.1.22 UDP-D-galactose + 2 NAD+ + H2O while the enzyme is able to process various sugar nucleotides, of those compounds tested, UDP-glucose is by far the preferred substrate of the enzyme Haloferax volcanii UDP-alpha-D-galacturonate + 2 NADH + 2 H+ - ? 429002 1.1.1.22 UDP-D-galactose + 2 NAD+ + H2O while the enzyme is able to process various sugar nucleotides, of those compounds tested, UDP-glucose is by far the preferred substrate of the enzyme Haloferax volcanii DSM 3757 UDP-alpha-D-galacturonate + 2 NADH + 2 H+ - ? 429002 1.1.1.22 UDP-galactose + NAD+ + H2O 11.9% of the rate with UDP-glucose Pseudomonas aeruginosa UDP-galacturonate + NADH - ? 398487 1.1.1.22 UDP-galactose + NAD+ + H2O 6.4% of the rate with UDP-glucose Pseudomonas aeruginosa UDP-galacturonate + NADH - ? 398487 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Gallus gallus UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Phaseolus vulgaris UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Cavia porcellus UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Escherichia coli UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Homo sapiens UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Rattus norvegicus UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Bos taurus UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Pisum sativum UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Zea mays UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Glycine max UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Arabidopsis thaliana UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Streptococcus pyogenes UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Lilium longiflorum UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Papiliotrema laurentii UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Saccharum spp. UDP-glucuronate + 2 NADH + 2 H+ - ir 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Streptococcus equi subsp. zooepidemicus UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Caenorhabditis elegans UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Sphingomonas elodea UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Xenopus laevis UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Pseudomonas aeruginosa UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O reversal of reaction cannot be demonstrated Bos taurus UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O NADP+, about 1% of activity of NAD+ Glycine max UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O several different UDPGDH isoenzymes contribute to UDP-glucuronate and hence wall matrix biosynthesis in maize Zea mays UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O the enzyme has a crucial role during development of Xenopus laevis. Silencing of UGDH decreases glycosaminoglycan synthesis causing severe embryonic malformations because of defective gastrulation process Xenopus laevis UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O UDPGDH-A activity has a more important role than UDPGDH-B in synthesis of UDP-glucuronate Zea mays UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O C276 is an active catalytic residue and critically involved in the substrate binding Homo sapiens UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O the enzyme has dual specificity with UDP-glucose and ethanol Nicotiana tabacum UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O recombinant forms Ugd(BCAL2946) and Ugd(BCAM0855) have similar in vitro Ugd activity Burkholderia cenocepacia J2315 UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Streptococcus equi subsp. zooepidemicus FHA0 UDP-glucuronate + 2 NADH + 2 H+ - ? 187824 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Homo sapiens UDP-glucuronic acid + 2 NADH + 2 H+ - ? 413642 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Burkholderia cepacia UDP-glucuronic acid + 2 NADH + 2 H+ - ? 413642 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Sphingomonas elodea UDP-glucuronic acid + 2 NADH + 2 H+ - ? 413642 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Proteus mirabilis UDP-glucuronic acid + 2 NADH + 2 H+ - ? 413642 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Burkholderia cepacia IST408 UDP-glucuronic acid + 2 NADH + 2 H+ - ? 413642 1.1.1.22 UDP-glucose + 2 NAD+ + H2O - Sphingomonas elodea ATCC 31461 UDP-glucuronic acid + 2 NADH + 2 H+ - ? 413642 1.1.1.22 UDP-glucose + 3-acetylpyridine adenine dinucleotide + H2O - Escherichia coli UDP-glucuronate + ? - ? 355763 1.1.1.22 UDP-glucose + 3-acetylpyridine adenine dinucleotide + H2O - Bos taurus UDP-glucuronate + ? - ? 355763 1.1.1.22 UDP-glucose + 3-acetylpyridine adenine dinucleotide + H2O - Papiliotrema laurentii UDP-glucuronate + ? - ? 355763 1.1.1.22 UDP-glucose + 3-pyridinealdehyde adenine dinucleotide - Escherichia coli UDP-glucuronate - ? 355764 1.1.1.22 UDP-glucose + deamino adenine dinucleotide + H2O - Escherichia coli UDP-glucuronate + ? - ? 355766 1.1.1.22 UDP-glucose + deamino adenine dinucleotide + H2O - Bos taurus UDP-glucuronate + ? - ? 355766 1.1.1.22 UDP-glucose + nicotinamide hypoxanthine dinucleotide + H2O - Rattus norvegicus UDP-glucuronate + ? - ? 355767 1.1.1.22 UDP-glucose + thionicotinamide adenine dinucleotide + H2O - Escherichia coli UDP-glucuronate + ? - ? 355765 1.1.1.22 UDP-glucose + thionicotinamide adenine dinucleotide + H2O - Papiliotrema laurentii UDP-glucuronate + ? - ? 355765 1.1.1.22 UDP-N-acetylglucosamine + NAD+ + H2O 35% of the rate with UDP-glucose Pseudomonas aeruginosa ? + NADH - ? 398542 1.1.1.22 UDP-N-acetylglucosamine + NAD+ + H2O 6.3% of the rate with UDP-glucose Pseudomonas aeruginosa ? + NADH - ? 398542 1.1.1.22 UDPglucose + NAD+ + H2O - Gallus gallus UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Phaseolus vulgaris UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Cavia porcellus UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Escherichia coli UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Homo sapiens UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Rattus norvegicus UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Bos taurus UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Pisum sativum UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Glycine max UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O - Papiliotrema laurentii UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O first step of a branched pathway leading to plant cell-wall polysaccharides which contain glucuronic and galacturonic acids and the pentoses xylose, arabinose and apiose Lilium longiflorum UDPglucuronate + NADH - ? 369961 1.1.1.22 UDPglucose + NAD+ + H2O delivers glucuronic acid for the formation of a antiphagocytic polysaccharide capsule that is required for virulence of pathogenic bacteria Streptococcus pyogenes UDPglucuronate + NADH - ? 369961